Conservation of cofitness between PS417_28050 and PS417_24600 in Pseudomonas simiae WCS417

62 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_28050 hypothetical protein 1.0 PS417_24600 hydrogenase 0.66 2
Pseudomonas fluorescens SBW25-INTG 1.00 PFLU_RS29735 HlyC/CorC family transporter 0.98 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens SBW25 1.00 PFLU_RS29735 HlyC/CorC family transporter 0.98 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_09865 hypothetical protein 0.90 AO353_06350 hydrogenase 0.34 25
Pseudomonas fluorescens FW300-N2E2 0.91 Pf6N2E2_4068 Phosphate regulon metal ion transporter containing CBS domains 0.79 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 103
Pseudomonas fluorescens FW300-N2C3 0.91 AO356_11010 hypothetical protein 0.89 AO356_15435 hydrogenase low > 104
Pseudomonas sp. RS175 0.91 PFR28_04481 hypothetical protein 0.86 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 88
Pseudomonas fluorescens GW456-L13 0.89 PfGW456L13_760 Phosphate regulon metal ion transporter containing CBS domains 0.89 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.89 Psyr_5034 CBS:Protein of unknown function DUF21:Transporter-associated region 0.84 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas syringae pv. syringae B728a 0.89 Psyr_5034 CBS:Protein of unknown function DUF21:Transporter-associated region 0.84 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas fluorescens FW300-N1B4 0.89 Pf1N1B4_2042 Phosphate regulon metal ion transporter containing CBS domains 0.80 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas putida KT2440 0.85 PP_5322 putative metal ion transporter 0.83 PP_4782 Phosphomethylpyrimidine kinase low > 96
Pseudomonas stutzeri RCH2 0.81 Psest_3847 Hemolysins and related proteins containing CBS domains 0.77 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 67
Pseudomonas sp. S08-1 0.78 OH686_13455 Phosphate regulon metal ion transporter containing CBS domains 0.81 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD low > 80
Paraburkholderia bryophila 376MFSha3.1 0.44 H281DRAFT_06055 Hemolysin, contains CBS domains 0.22 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase — —
Herbaspirillum seropedicae SmR1 0.43 HSERO_RS05435 hemolysin protein 0.29 HSERO_RS02135 phosphomethylpyrimidine kinase low > 78
Burkholderia phytofirmans PsJN 0.43 BPHYT_RS33815 hypothetical protein 0.20 BPHYT_RS12250 phosphomethylpyrimidine kinase — —
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS17705 hemolysin family protein 0.20 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Paraburkholderia graminis OAS925 0.42 ABIE53_004821 CBS domain containing-hemolysin-like protein 0.20 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.3404.1 FIG01211089: hypothetical protein 0.23 Xcc-8004.3091.1 hypothetical protein low > 74
Rhodopseudomonas palustris CGA009 0.27 TX73_002605 hemolysin family protein 0.21 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Pedobacter sp. GW460-11-11-14-LB5 0.24 CA265_RS23615 hemolysin 0.19 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.21 ABZR88_RS17090 hemolysin family protein 0.24 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Synechococcus elongatus PCC 7942 0.18 Synpcc7942_2595 hypothetical protein 0.16 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase low > 38
Mycobacterium tuberculosis H37Rv 0.17 Rv1842c Conserved hypothetical membrane protein 0.17 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) — —
Sinorhizobium meliloti 1021 0.16 SMc00240 hypothetical protein 0.20 SM_b20962 phoshomethylpyrimidine kinase low > 103
Bifidobacterium breve UCC2003 0.16 BBR_RS10445 HlyC/CorC family transporter 0.24 BBR_RS17215 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 34
Dyella japonica UNC79MFTsu3.2 0.16 ABZR86_RS19900 hemolysin family protein 0.22 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Bacteroides stercoris CC31F 0.16 HMPREF1181_RS05310 HlyC/CorC family transporter 0.25 HMPREF1181_RS14705 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 56
Rhodanobacter sp. FW510-T8 0.15 OKGIIK_02350 tlyC Hemolysin-related protein, contains CBS domains, UPF0053 family 0.20 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 52
Bacteroides thetaiotaomicron VPI-5482 0.15 BT0148 putative hemolysin (NCBI ptt file) 0.26 BT0790 phosphomethylpyrimidine kinase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.15 BACOVA_01289 hypothetical protein 0.25 BACOVA_02530 phosphomethylpyrimidine kinase low > 94
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS00430 hemolysin family protein 0.20 HMPREF1078_RS03470 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 61
Lysobacter sp. OAE881 0.15 ABIE51_RS06575 hemolysin family protein 0.20 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Desulfovibrio vulgaris Hildenborough JW710 0.14 DVU2148 CBS/transporter associated domain protein (TIGR) 0.18 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) — —
Pectobacterium carotovorum WPP14 0.14 HER17_RS03970 hemolysin family protein 0.25 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Pantoea sp. MT58 0.13 IAI47_02710 HlyC/CorC family transporter 0.21 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Variovorax sp. SCN45 0.13 GFF2520 UPF0053 inner membrane protein YtfL 0.16 GFF2149 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 127
Serratia liquefaciens MT49 0.13 IAI46_01760 HlyC/CorC family transporter 0.23 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Variovorax sp. OAS795 0.13 ABID97_RS07170 hemolysin family protein 0.19 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.13 GFF871 Putative membrane protein 0.23 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Ralstonia solanacearum GMI1000 0.13 RS_RS11430 HlyC/CorC family transporter 0.25 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Klebsiella michiganensis M5al 0.12 BWI76_RS02765 membrane protein 0.23 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Dickeya dadantii 3937 0.12 DDA3937_RS17170 HlyC/CorC family transporter 0.21 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Dickeya dianthicola ME23 0.12 DZA65_RS18310 HlyC/CorC family transporter 0.20 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Dickeya dianthicola 67-19 0.12 HGI48_RS17225 HlyC/CorC family transporter 0.21 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Escherichia coli ECRC102 0.12 NIAGMN_09865 paeA Polyamine export protein 0.24 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli Nissle 1917 0.12 ECOLIN_RS24495 hemolysin family protein 0.24 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC99 0.12 KEDOAH_16140 paeA Polyamine export protein 0.24 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.12 OHPLBJKB_03816 hypothetical protein 0.24 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia coli ECOR27 0.12 NOLOHH_04280 paeA Polyamine export protein 0.24 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 57
Escherichia coli BL21 0.12 ECD_04089 UPF0053 family inner membrane protein 0.24 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase low > 60
Enterobacter sp. TBS_079 0.12 MPMX20_00495 hypothetical protein 0.23 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 85
Escherichia coli ECRC101 0.12 OKFHMN_12015 paeA Polyamine export protein 0.24 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC101 0.12 MCAODC_02530 paeA Polyamine export protein 0.24 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC98 0.12 JDDGAC_15655 paeA Polyamine export protein 0.24 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli BW25113 0.12 b4218 ytfL predicted inner membrane protein (NCBI) 0.24 b2103 thiD phosphomethylpyrimidine kinase (NCBI) low > 76
Escherichia coli ECOR38 0.12 HEPCGN_10215 paeA Polyamine export protein 0.24 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 85
Enterobacter asburiae PDN3 0.12 EX28DRAFT_3404 Hemolysins and related proteins containing CBS domains 0.23 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Escherichia coli ECRC62 0.12 BNILDI_07240 tlyC Polyamine export protein 0.24 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia fergusonii Becca 0.12 EFB2_04311 hypothetical protein 0.24 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Erwinia tracheiphila SCR3 0.12 LU632_RS02100 hemolysin family protein 0.22 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Rahnella sp. WP5 0.12 EX31_RS08705 HlyC/CorC family transporter 0.23 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89

Not shown: 5 genomes with orthologs for PS417_28050 only; 31 genomes with orthologs for PS417_24600 only