Conservation of cofitness between PS417_18585 and PS417_18530 in Pseudomonas simiae WCS417

51 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas simiae WCS417 1.0 PS417_18585 3-isopropylmalate dehydrogenase 1.0 PS417_18530 O-succinylhomoserine sulfhydrylase 0.91 8
Pseudomonas fluorescens SBW25-INTG 0.99 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.99 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.87 6
Pseudomonas fluorescens SBW25 0.99 PFLU_RS20565 3-isopropylmalate dehydrogenase 0.99 PFLU_RS20510 O-succinylhomoserine sulfhydrylase 0.86 3
Pseudomonas fluorescens FW300-N2E2 0.97 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.94 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.94 7
Pseudomonas fluorescens FW300-N2C3 0.97 AO356_21415 3-isopropylmalate dehydrogenase 0.94 AO356_21470 O-succinylhomoserine sulfhydrylase 0.96 4
Pseudomonas sp. RS175 0.95 PFR28_02821 3-isopropylmalate dehydrogenase 0.95 PFR28_02810 O-succinylhomoserine sulfhydrylase 0.52 29
Pseudomonas fluorescens GW456-L13 0.95 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.94 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.97 4
Pseudomonas syringae pv. syringae B728a 0.94 Psyr_1985 3-isopropylmalate dehydrogenase 0.96 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.97 2
Pseudomonas syringae pv. syringae B728a ΔmexB 0.94 Psyr_1985 3-isopropylmalate dehydrogenase 0.96 Psyr_1669 O-succinylhomoserine sulfhydrylase 0.97 1
Pseudomonas fluorescens FW300-N2E3 0.94 AO353_20635 3-isopropylmalate dehydrogenase 0.95 AO353_20695 O-succinylhomoserine sulfhydrylase 0.96 8
Pseudomonas putida KT2440 0.93 PP_1988 3-isopropylmalate dehydrogenase 0.88 PP_2001 O-succinylhomoserine sulfhydrylase 0.89 15
Pseudomonas sp. S08-1 0.88 OH686_04470 3-isopropylmalate dehydrogenase 0.82 OH686_04415 O-succinylhomoserine sulfhydrylase 0.83 17
Pseudomonas stutzeri RCH2 0.87 Psest_2589 3-isopropylmalate dehydrogenase 0.85 Psest_2578 O-succinylhomoserine sulfhydrylase 0.95 2
Acinetobacter radioresistens SK82 0.73 MPMX26_00348 3-isopropylmalate dehydrogenase 0.66 MPMX26_01645 O-succinylhomoserine sulfhydrylase 0.90 26
Marinobacter adhaerens HP15 0.71 HP15_1832 3-isopropylmalate dehydrogenase 0.62 HP15_1820 methionine gamma-lyase 0.91 10
Dechlorosoma suillum PS 0.69 Dsui_3198 3-isopropylmalate dehydrogenase 0.57 Dsui_3185 O-succinylhomoserine sulfhydrylase — —
Variovorax sp. OAS795 0.64 ABID97_RS08455 3-isopropylmalate dehydrogenase 0.54 ABID97_RS21630 O-succinylhomoserine sulfhydrylase — —
Paraburkholderia bryophila 376MFSha3.1 0.64 H281DRAFT_06072 3-isopropylmalate dehydrogenase 0.54 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase 0.73 6
Paraburkholderia graminis OAS925 0.64 ABIE53_004804 3-isopropylmalate dehydrogenase 0.55 ABIE53_004817 O-succinylhomoserine sulfhydrylase 0.96 3
Variovorax sp. SCN45 0.64 GFF3888 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.55 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) — —
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS14385 3-isopropylmalate dehydrogenase 0.55 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.80 13
Hydrogenophaga sp. GW460-11-11-14-LB1 0.63 GFF3360 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.52 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) 0.82 18
Burkholderia phytofirmans PsJN 0.63 BPHYT_RS33900 3-isopropylmalate dehydrogenase 0.54 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.96 3
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS17620 3-isopropylmalate dehydrogenase 0.54 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Phaeobacter inhibens DSM 17395 0.60 PGA1_c29830 3-isopropylmalate dehydrogenase LeuB 0.43 PGA1_c23540 O-succinylhomoserine sulfhydrylase MetZ 0.85 27
Dinoroseobacter shibae DFL-12 0.59 Dshi_0081 3-isopropylmalate dehydrogenase (RefSeq) 0.46 Dshi_2410 O-succinylhomoserine sulfhydrylase (RefSeq) — —
Sinorhizobium meliloti 1021 0.59 SMc04405 3-isopropylmalate dehydrogenase 0.42 SMc02217 O-succinylhomoserine sulfhydrylase 0.97 7
Agrobacterium fabrum C58 0.59 Atu2791 3-isopropylmalate dehydrogenase 0.43 Atu0432 O-succinylhomoserine sulfhydrylase 0.96 6
Azospirillum sp. SherDot2 0.59 MPMX19_00607 3-isopropylmalate dehydrogenase 0.40 MPMX19_01364 O-succinylhomoserine sulfhydrylase 0.95 3
Rhizobium sp. OAE497 0.59 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.42 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase 0.98 7
Synechococcus elongatus PCC 7942 0.58 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase 0.35 Synpcc7942_0370 metY O-acetylhomoserine/O-acetylserine sulfhydrylase — —
Rhodospirillum rubrum S1H 0.58 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) 0.43 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) 0.81 32
Magnetospirillum magneticum AMB-1 0.56 AMB_RS20570 3-isopropylmalate dehydrogenase 0.47 AMB_RS21365 O-succinylhomoserine sulfhydrylase — —
Azospirillum brasilense Sp245 0.56 AZOBR_RS14130 3-isopropylmalate dehydrogenase 0.43 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase 0.87 6
Sphingomonas koreensis DSMZ 15582 0.56 Ga0059261_3190 3-isopropylmalate dehydrogenase 0.41 Ga0059261_3194 O-acetylhomoserine sulfhydrylase (EC:2.5.1.49) (from data) 0.87 57
Rhodopseudomonas palustris CGA009 0.55 TX73_001175 3-isopropylmalate dehydrogenase 0.43 TX73_024775 O-succinylhomoserine sulfhydrylase — —
Bosea sp. OAE506 0.54 ABIE41_RS11860 3-isopropylmalate dehydrogenase 0.44 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase — —
Caulobacter crescentus NA1000 0.52 CCNA_00193 3-isopropylmalate dehydrogenase 0.42 CCNA_02321 O-succinylhomoserine sulfhydrylase 0.93 22
Caulobacter crescentus NA1000 Δfur 0.52 CCNA_00193 3-isopropylmalate dehydrogenase 0.42 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 67
Pantoea sp. MT58 0.50 IAI47_16005 3-isopropylmalate dehydrogenase 0.29 IAI47_00880 cystathionine gamma-synthase 0.98 4
Lysobacter sp. OAE881 0.49 ABIE51_RS17585 3-isopropylmalate dehydrogenase 0.39 ABIE51_RS04295 cystathionine gamma-synthase low > 62
Pedobacter sp. GW460-11-11-14-LB5 0.48 CA265_RS15850 3-isopropylmalate dehydrogenase 0.48 CA265_RS13080 O-succinylhomoserine sulfhydrylase 0.92 20
Echinicola vietnamensis KMM 6221, DSM 17526 0.46 Echvi_2062 3-isopropylmalate dehydrogenase 0.49 Echvi_2283 Cystathionine beta-lyases/cystathionine gamma-synthases — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.43 CA264_09445 3-isopropylmalate dehydrogenase 0.45 CA264_02530 O-succinylhomoserine sulfhydrylase low > 74
Parabacteroides merdae CL09T00C40 0.43 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase 0.34 HMPREF1078_RS07330 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 61
Bacteroides stercoris CC31F 0.43 HMPREF1181_RS14125 3-isopropylmalate dehydrogenase 0.37 HMPREF1181_RS05290 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 56
Phocaeicola vulgatus CL09T03C04 0.42 HMPREF1058_RS14565 3-isopropylmalate dehydrogenase 0.38 HMPREF1058_RS17635 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 67
Phocaeicola dorei CL03T12C01 0.41 ABI39_RS10215 3-isopropylmalate dehydrogenase 0.38 ABI39_RS13825 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 72
Bacteroides thetaiotaomicron VPI-5482 0.41 BT1857 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.38 BT2387 O-acetylhomoserine (thiol)-lyase (NCBI ptt file) low > 81
Bacteroides ovatus ATCC 8483 0.41 BACOVA_04600 3-isopropylmalate dehydrogenase 0.38 BACOVA_03030 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 94
Mycobacterium tuberculosis H37Rv 0.28 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.43 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) — —
Bifidobacterium breve UCC2003 0.27 BBR_RS12870 3-isopropylmalate dehydrogenase 0.34 BBR_RS14595 O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase low > 34

Not shown: 51 genomes with orthologs for PS417_18585 only; 0 genomes with orthologs for PS417_18530 only