Conservation of cofitness between ECD_00652 and ECD_02594 in Escherichia coli BL21

65 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00652 fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein 1.0 ECD_02594 broad specificity 5'(3')-nucleotidase and polyphosphatase 0.45 50
Escherichia coli ECRC100 1.00 OKFHMN_07075 kdpD two-component system sensor histidine kinase KdpD 1.00 OKFHMN_20480 surE 5'/3'-nucleotidase SurE low > 80
Escherichia coli ECRC98 1.00 JDDGAC_10725 kdpD two-component system sensor histidine kinase KdpD 1.00 JDDGAC_24145 surE 5'/3'-nucleotidase SurE low > 86
Escherichia coli ECRC102 1.00 NIAGMN_05130 kdpD two-component system sensor histidine kinase KdpD 1.00 NIAGMN_18250 surE 5'/3'-nucleotidase SurE — —
Escherichia coli ECRC99 1.00 KEDOAH_20895 kdpD two-component system sensor histidine kinase KdpD 1.00 KEDOAH_07660 surE 5'/3'-nucleotidase SurE — —
Escherichia coli ECRC101 1.00 MCAODC_26290 kdpD two-component system sensor histidine kinase KdpD 1.00 MCAODC_11005 surE 5'/3'-nucleotidase SurE low > 87
Escherichia coli BW25113 1.00 b0695 kdpD fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein (NCBI) 1.00 b2744 surE acid phosphatase (NCBI) low > 76
Escherichia coli ECOR38 1.00 HEPCGN_01160 kdpD two-component system sensor histidine kinase KdpD 0.99 HEPCGN_19660 surE 5'/3'-nucleotidase SurE low > 87
Escherichia coli ECOR27 1.00 NOLOHH_23455 kdpD two-component system sensor histidine kinase KdpD 1.00 NOLOHH_12295 surE 5'/3'-nucleotidase SurE low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_03022 Sensor protein KdpD 1.00 OHPLBJKB_00989 '5'/3'-nucleotidase SurE' transl_table=11 low > 73
Escherichia coli ECRC62 1.00 BNILDI_21460 kdpD two-component system sensor histidine kinase KdpD 1.00 BNILDI_10845 surE 5'/3'-nucleotidase SurE low > 75
Escherichia coli Nissle 1917 0.99 ECOLIN_RS03755 two-component system sensor histidine kinase KdpD 1.00 ECOLIN_RS15345 5'/3'-nucleotidase SurE low > 55
Escherichia fergusonii Becca 0.99 EFB2_03401 Sensor protein KdpD 1.00 EFB2_01166 5'/3'-nucleotidase SurE low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.88 GFF4607 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.92 GFF4792 5-nucleotidase SurE (EC 3.1.3.5) @ Exopolyphosphatase (EC 3.6.1.11) low > 78
Enterobacter asburiae PDN3 0.83 EX28DRAFT_2283 Osmosensitive K+ channel histidine kinase 0.92 EX28DRAFT_2840 3'-nucleotidase (EC 3.1.3.6)/5'-nucleotidase (EC 3.1.3.5)/exopolyphosphatase (EC 3.6.1.11) low > 76
Enterobacter sp. TBS_079 0.83 MPMX20_01338 Sensor protein KdpD 0.92 MPMX20_03630 5'/3'-nucleotidase SurE low > 85
Klebsiella michiganensis M5al 0.83 BWI76_RS08305 two-component sensor histidine kinase 0.92 BWI76_RS22660 5'/3'-nucleotidase SurE low > 92
Rahnella sp. WP5 0.68 EX31_RS23335 two-component system sensor histidine kinase KdbD 0.79 EX31_RS07840 5'/3'-nucleotidase SurE low > 89
Serratia liquefaciens MT49 0.68 IAI46_06165 two-component system sensor histidine kinase KdbD 0.83 IAI46_03775 5'/3'-nucleotidase SurE low > 86
Pantoea sp. MT58 0.66 IAI47_01250 two-component system sensor histidine kinase KdbD 0.87 IAI47_04220 5'/3'-nucleotidase SurE low > 76
Erwinia tracheiphila SCR3 0.66 LU632_RS00800 kdpD two-component system sensor histidine kinase KdpD 0.85 LU632_RS06465 surE 5'/3'-nucleotidase SurE low > 74
Pseudomonas fluorescens FW300-N2E3 0.50 AO353_28955 sensor protein KdpD 0.43 AO353_16600 stationary phase survival protein SurE low > 101
Dechlorosoma suillum PS 0.45 Dsui_0272 osmosensitive K+ channel histidine kinase 0.44 Dsui_1968 5''/3''-nucleotidase SurE low > 51
Paraburkholderia sabiae LMG 24235 0.43 QEN71_RS24345 DUF4118 domain-containing protein 0.44 QEN71_RS22255 5'/3'-nucleotidase SurE low > 153
Burkholderia phytofirmans PsJN 0.42 BPHYT_RS06460 histidine kinase 0.44 BPHYT_RS09100 stationary phase survival protein SurE 0.17 47
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS00495 histidine kinase 0.42 RR42_RS13200 stationary phase survival protein SurE 0.37 49
Paraburkholderia bryophila 376MFSha3.1 0.42 H281DRAFT_04532 two-component system, OmpR family, sensor histidine kinase KdpD 0.43 H281DRAFT_00840 5'-nucleotidase /3'-nucleotidase /exopolyphosphatase low > 103
Paraburkholderia graminis OAS925 0.41 ABIE53_001556 two-component system sensor histidine kinase KdpD 0.44 ABIE53_002054 5'-nucleotidase low > 113
Acidovorax sp. GW101-3H11 0.41 Ac3H11_2408 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.41 Ac3H11_1784 5-nucleotidase SurE (EC 3.1.3.5) low > 79
Ralstonia solanacearum PSI07 0.40 RPSI07_RS08140 sensor histidine kinase KdpD 0.42 RPSI07_RS18155 5'/3'-nucleotidase SurE low > 81
Ralstonia solanacearum GMI1000 0.40 RS_RS16960 sensor histidine kinase KdpD 0.42 RS_RS06030 5'-nucleotidase SurE low > 80
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS09130 sensor histidine kinase KdpD 0.42 RALBFv3_RS15220 5'/3'-nucleotidase SurE low > 76
Variovorax sp. SCN45 0.40 GFF3520 Osmosensitive K+ channel histidine kinase KdpD 0.44 GFF2845 5'-nucleotidase SurE (EC 3.1.3.5) low > 127
Ralstonia solanacearum UW163 0.40 UW163_RS04465 sensor histidine kinase KdpD 0.42 UW163_RS12685 5'/3'-nucleotidase SurE — —
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS18855 sensor protein KdpD 0.43 HSERO_RS14845 stationary phase survival protein SurE 0.24 48
Variovorax sp. OAS795 0.39 ABID97_RS01010 DUF4118 domain-containing protein 0.44 ABID97_RS10715 5'/3'-nucleotidase SurE low > 91
Ralstonia sp. UNC404CL21Col 0.39 ABZR87_RS04525 sensor histidine kinase KdpD 0.42 ABZR87_RS10860 5'/3'-nucleotidase SurE — —
Agrobacterium fabrum C58 0.34 Atu3787 two component sensor kinase 0.31 Atu1702 stationary-phase survival protein low > 89
Rhizobium sp. OAE497 0.33 ABIE40_RS24610 sensor histidine kinase KdpD 0.31 ABIE40_RS08480 5'/3'-nucleotidase SurE low > 107
Azospirillum brasilense Sp245 0.33 AZOBR_RS23975 histidine kinase 0.36 AZOBR_RS15460 5'-nucleotidase low > 97
Rhodopseudomonas palustris CGA009 0.31 TX73_015550 sensor histidine kinase KdpD 0.32 TX73_014710 5'/3'-nucleotidase SurE low > 86
Magnetospirillum magneticum AMB-1 0.31 AMB_RS09655 sensor histidine kinase KdpD 0.35 AMB_RS12675 5'-nucleotidase SurE — —
Azospirillum sp. SherDot2 0.31 MPMX19_03748 Sensor protein KdpD 0.33 MPMX19_01169 5'-nucleotidase SurE low > 112
Rhodospirillum rubrum S1H 0.31 Rru_A1158 Osmosensitive K+ channel Signal Transduction Histidine Kinase (NCBI) 0.34 Rru_A1769 Acid phosphatase (NCBI) — —
Bosea sp. OAE506 0.30 ABIE41_RS24230 sensor histidine kinase KdpD 0.33 ABIE41_RS15015 5'/3'-nucleotidase SurE low > 77
Dyella japonica UNC79MFTsu3.2 0.28 ABZR86_RS13210 sensor histidine kinase KdpD 0.53 ABZR86_RS06595 5'/3'-nucleotidase SurE low > 74
Pseudomonas fluorescens FW300-N2E2 0.28 Pf6N2E2_2491 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.40 Pf6N2E2_3040 5-nucleotidase SurE (EC 3.1.3.5) low > 103
Pseudomonas sp. S08-1 0.27 OH686_01890 Osmosensitive K+ channel histidine kinase KdpD 0.45 OH686_18170 5'/3'-nucleotidase SurE low > 80
Pseudomonas sp. RS175 0.27 PFR28_00942 Sensor protein KdpD 0.40 PFR28_00424 '5'-nucleotidase SurE' transl_table=11 low > 88
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_03300 histidine kinase 0.40 AO356_05900 stationary phase survival protein SurE low > 104
Sinorhizobium meliloti 1021 0.27 SMa2327 sensor protein 0.32 SMc02063 stationary phase survival protein SurE — —
Sphingomonas koreensis DSMZ 15582 0.27 Ga0059261_3881 Osmosensitive K+ channel histidine kinase 0.30 Ga0059261_0278 3'-nucleotidase (EC 3.1.3.6)/5'-nucleotidase (EC 3.1.3.5)/exopolyphosphatase (EC 3.6.1.11) low > 68
Caulobacter crescentus NA1000 Δfur 0.27 CCNA_01666 osmosensitive K+ channel histidine kinase kdpD 0.34 CCNA_02077 5'(3')-nucleotidase/polyphosphatase SurE low > 67
Caulobacter crescentus NA1000 0.27 CCNA_01666 osmosensitive K+ channel histidine kinase kdpD 0.34 CCNA_02077 5'(3')-nucleotidase/polyphosphatase SurE low > 66
Hydrogenophaga sp. GW460-11-11-14-LB1 0.26 GFF4474 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.43 GFF3879 5-nucleotidase SurE (EC 3.1.3.5) low > 90
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_2204 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.43 PfGW456L13_4678 5-nucleotidase SurE (EC 3.1.3.5) @ Exopolyphosphatase (EC 3.6.1.11) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.26 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.44 Psyr_1371 5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase low > 86
Pseudomonas syringae pv. syringae B728a 0.26 Psyr_2050 ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Osmosensitive K+ channel His kinase sensor:UspA 0.44 Psyr_1371 5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase low > 86
Pseudomonas simiae WCS417 0.26 PS417_08300 histidine kinase 0.43 PS417_06350 stationary phase survival protein SurE low > 88
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS08240 sensor histidine kinase KdpD 0.43 PFLU_RS06415 5'/3'-nucleotidase SurE low > 109
Pseudomonas fluorescens SBW25 0.26 PFLU_RS08240 sensor histidine kinase KdpD 0.43 PFLU_RS06415 5'/3'-nucleotidase SurE low > 109
Xanthomonas campestris pv. campestris strain 8004 0.25 Xcc-8004.4379.1 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.51 Xcc-8004.3131.1 hypothetical protein low > 74
Pseudomonas putida KT2440 0.25 PP_4158 sensor protein 0.44 PP_1620 5'(3')-nucleotidase and polyphosphatase low > 96
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_312 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) 0.43 Pf1N1B4_3112 5-nucleotidase SurE (EC 3.1.3.5) @ Exopolyphosphatase (EC 3.6.1.11) low > 87
Brevundimonas sp. GW460-12-10-14-LB2 0.24 A4249_RS15630 sensor histidine kinase KdpD 0.34 A4249_RS04645 5'/3'-nucleotidase SurE low > 48
Acinetobacter radioresistens SK82 0.23 MPMX26_02241 Sensor protein KdpD 0.36 MPMX26_01054 5'-nucleotidase SurE — —

Not shown: 5 genomes with orthologs for ECD_00652 only; 30 genomes with orthologs for ECD_02594 only