| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_06735 | | methylisocitrate lyase | 1.0 | CSW01_12885 | | fructose 1,6-bisphosphatase | 0.87 | 13 |
| Alteromonas macleodii MIT1002 | 0.67 | MIT1002_03129 | | Methylisocitrate lyase | 0.35 | MIT1002_00169 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Shewanella loihica PV-4 | 0.67 | Shew_1820 | prpB | 2-methylisocitrate lyase (RefSeq) | 0.35 | Shew_0773 | | fructose-1,6-bisphosphatase (RefSeq) | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.65 | DY961_RS08515 | prpB;go_function=methylisocitrate | methylisocitrate lyase | 0.39 | DY961_RS11375 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas aeruginosa PA14 | 0.65 | IKLFDK_03445 | | methylisocitrate lyase | 0.40 | IKLFDK_27970 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas aeruginosa PUPa3 | 0.65 | DQ20_RS44335 | prpB;go_function=methylisocitrate | methylisocitrate lyase | 0.39 | DQ20_RS50720 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.64 | AO353_00900 | | 2-methylisocitrate lyase | 0.38 | AO353_12205 | | fructose 1,6-bisphosphatase | — | — |
| Pseudomonas sp. RS175 | 0.64 | PFR28_02928 | | 2-methylisocitrate lyase | 0.38 | PFR28_04956 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.64 | AO356_20865 | | 2-methylisocitrate lyase | 0.38 | AO356_09670 | | fructose 1,6-bisphosphatase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.63 | Pf1N1B4_3819 | | Methylisocitrate lyase (EC 4.1.3.30) | 0.39 | Pf1N1B4_1596 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.63 | Pf6N2E2_6061 | | Methylisocitrate lyase (EC 4.1.3.30) (from data) | 0.38 | Pf6N2E2_3813 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Pseudomonas sp. DMC3 | 0.63 | GFF5230 | | 2-methylisocitrate lyase | 0.38 | GFF4070 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas stutzeri RCH2 | 0.63 | Psest_2321 | | methylisocitrate lyase | 0.39 | Psest_3956 | | Fructose-1,6-bisphosphatase | — | — |
| Pseudomonas putida KT2440 | 0.63 | PP_2334 | | 2-methylisocitrate lyase | 0.39 | PP_5040 | | fructose-1,6-bisphosphatase, class 1 | — | — |
| Pseudomonas sp. SVBP6 | 0.63 | COO64_RS09900 | prpB | methylisocitrate lyase | 0.39 | COO64_RS13370 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas simiae WCS417 | 0.63 | PS417_21080 | | 2-methylisocitrate lyase | 0.38 | PS417_01690 | | fructose 1,6-bisphosphatase | — | — |
| Shewanella sp. ANA-3 | 0.63 | Shewana3_3825 | prpB | 2-methylisocitrate lyase (RefSeq) | 0.35 | Shewana3_0648 | | fructose-1,6-bisphosphatase (RefSeq) | low | > 73 |
| Pseudomonas sp. BP01 | 0.63 | JOY50_RS25750 | prpB | methylisocitrate lyase | 0.38 | JOY50_RS09485 | | class 1 fructose-bisphosphatase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.63 | HSERO_RS15660 | | 2-methylisocitrate lyase | 0.41 | HSERO_RS17715 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Shewanella oneidensis MR-1 | 0.63 | SO0345 | prpB | methylisocitrate lyase (NCBI ptt file) | 0.35 | SO3991 | fbp | fructose-1,6-bisphosphatase (NCBI ptt file) | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.63 | RALBFv3_RS02670 | | methylisocitrate lyase | 0.40 | RALBFv3_RS03275 | | class 1 fructose-bisphosphatase | — | — |
| Ralstonia solanacearum UW163 | 0.63 | UW163_RS11055 | | methylisocitrate lyase | 0.40 | UW163_RS10450 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.63 | PfGW456L13_4118 | | Methylisocitrate lyase (EC 4.1.3.30) | 0.39 | PfGW456L13_335 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Pseudomonas orientalis W4I3 | 0.63 | QF045_RS22905 | | methylisocitrate lyase | 0.38 | QF045_RS04755 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas fluorescens SBW25 | 0.62 | PFLU_RS22690 | | methylisocitrate lyase | 0.37 | PFLU_RS01745 | | class 1 fructose-bisphosphatase | — | — |
| Ralstonia solanacearum PSI07 | 0.62 | RPSI07_RS14645 | | methylisocitrate lyase | 0.40 | RPSI07_RS14035 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas lactucae CFBP13502 | 0.62 | GEMAOFIL_04361 | | 2-methylisocitrate lyase | 0.38 | GEMAOFIL_00560 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.62 | PFLU_RS22690 | | methylisocitrate lyase | 0.37 | PFLU_RS01745 | | class 1 fructose-bisphosphatase | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.62 | Psyr_2085 | | methylisocitrate lyase | 0.38 | Psyr_0370 | | D-fructose 1,6-bisphosphatase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.62 | Psyr_2085 | | methylisocitrate lyase | 0.38 | Psyr_0370 | | D-fructose 1,6-bisphosphatase | — | — |
| Methylophilus sp. DMC18 | 0.62 | GFF469 | | 2-methylisocitrate lyase | 0.31 | GFF2746 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Pseudomonas segetis P6 | 0.62 | MPMX49_02628 | | 2-methylisocitrate lyase | 0.40 | MPMX49_04276 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Ralstonia solanacearum GMI1000 | 0.62 | RS_RS10050 | | methylisocitrate lyase | 0.41 | RS_RS10665 | | fructose 1,6-bisphosphatase | — | — |
| Ralstonia sp. UNC404CL21Col | 0.62 | ABZR87_RS14590 | | methylisocitrate lyase | 0.41 | ABZR87_RS15125 | | class 1 fructose-bisphosphatase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.62 | QEN71_RS17555 | | methylisocitrate lyase | 0.41 | QEN71_RS03770 | | class 1 fructose-bisphosphatase | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.62 | OHPLBJKB_03339 | | 2-methylisocitrate lyase | 0.76 | OHPLBJKB_03803 | | Fructose-1,6-bisphosphatase class 1 | low | > 74 |
| Cupriavidus basilensis FW507-4G11 | 0.62 | RR42_RS11260 | | Methylisocitrate lyase (EC 4.1.3.30) (from data) | 0.40 | RR42_RS05195 | | fructose 1,6-bisphosphatase | — | — |
| Escherichia coli ECRC62 | 0.62 | BNILDI_23190 | prpB | methylisocitrate lyase | 0.76 | BNILDI_07310 | fbp | class 1 fructose-bisphosphatase | low | > 75 |
| Escherichia coli ECOR38 | 0.62 | HEPCGN_07485 | prpB | methylisocitrate lyase | 0.76 | HEPCGN_10145 | fbp | class 1 fructose-bisphosphatase | low | > 88 |
| Escherichia coli ECOR27 | 0.62 | NOLOHH_01775 | prpB | methylisocitrate lyase | 0.76 | NOLOHH_04205 | fbp | class 1 fructose-bisphosphatase | low | > 76 |
| Escherichia coli BW25113 | 0.62 | b0331 | prpB | 2-methylisocitrate lyase (NCBI) | 0.76 | b4232 | fbp | fructose-1,6-bisphosphatase (NCBI) | low | > 76 |
| Escherichia fergusonii Becca | 0.62 | EFB2_03706 | | 2-methylisocitrate lyase | 0.76 | EFB2_04301 | | Fructose-1,6-bisphosphatase class 1 | low | > 86 |
| Escherichia coli BL21 | 0.62 | ECD_00286 | | 2-methylisocitrate lyase | 0.76 | ECD_04100 | | fructose-1,6-bisphosphatase I | low | > 61 |
| Escherichia coli ECRC101 | 0.61 | MCAODC_28130 | prpB | methylisocitrate lyase | 0.76 | MCAODC_02450 | fbp | class 1 fructose-bisphosphatase | low | > 87 |
| Escherichia coli ECRC102 | 0.61 | NIAGMN_06955 | prpB | methylisocitrate lyase | 0.76 | NIAGMN_09795 | fbp | class 1 fructose-bisphosphatase | low | > 80 |
| Shewanella amazonensis SB2B | 0.61 | Sama_3294 | prpB | 2-methylisocitrate lyase (RefSeq) | 0.37 | Sama_0599 | | fructose-1,6-bisphosphatase (RefSeq) | — | — |
| Escherichia coli Nissle 1917 | 0.61 | ECOLIN_RS02150 | | methylisocitrate lyase | 0.76 | ECOLIN_RS24555 | | class 1 fructose-bisphosphatase | low | > 55 |
| Escherichia coli ECRC100 | 0.61 | OKFHMN_08900 | prpB | methylisocitrate lyase | 0.76 | OKFHMN_11945 | fbp | class 1 fructose-bisphosphatase | low | > 79 |
| Escherichia coli ECRC99 | 0.61 | KEDOAH_19065 | prpB | methylisocitrate lyase | 0.76 | KEDOAH_16210 | fbp | class 1 fructose-bisphosphatase | — | — |
| Escherichia coli ECRC98 | 0.61 | JDDGAC_12555 | prpB | methylisocitrate lyase | 0.76 | JDDGAC_15585 | fbp | class 1 fructose-bisphosphatase | low | > 87 |
| Rhodanobacter sp000427505 FW510-R12 | 0.60 | LRK53_RS09460 | | methylisocitrate lyase | 0.35 | LRK53_RS00140 | | class 1 fructose-bisphosphatase | low | > 59 |
| Acinetobacter radioresistens SK82 | 0.60 | MPMX26_01289 | | 2-methylisocitrate lyase | 0.37 | MPMX26_02197 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Acinetobacter baumannii LAC-4 | 0.60 | RR41_RS18485 | | methylisocitrate lyase | 0.39 | RR41_RS04640 | | class 1 fructose-bisphosphatase | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.59 | GFF4263 | | Methylisocitrate lyase (EC 4.1.3.30) | 0.76 | GFF880 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | low | > 78 |
| Rhodanobacter sp. FW510-T8 | 0.59 | OKGIIK_06565 | prpB | methylisocitrate lyase | 0.36 | OKGIIK_15125 | fbp | class 1 fructose-bisphosphatase | low | > 53 |
| Rhodanobacter denitrificans FW104-10B01 | 0.58 | LRK54_RS00695 | | methylisocitrate lyase | 0.36 | LRK54_RS08365 | | class 1 fructose-bisphosphatase | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.58 | LRK55_RS00470 | | methylisocitrate lyase | 0.36 | LRK55_RS08130 | | class 1 fructose-bisphosphatase | low | > 63 |
| Castellaniella sp019104865 MT123 | 0.58 | ABCV34_RS01670 | | methylisocitrate lyase | 0.40 | ABCV34_RS02565 | | class 1 fructose-bisphosphatase | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.58 | Xcc-8004.3981.1 | | Methylisocitrate lyase (EC 4.1.3.30) | 0.38 | Xcc-8004.127.1 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | low | > 74 |
| Lysobacter sp. OAE881 | 0.57 | ABIE51_RS06015 | | methylisocitrate lyase | 0.36 | ABIE51_RS00860 | | class 1 fructose-bisphosphatase | low | > 62 |
| Dyella japonica UNC79MFTsu3.2 | 0.56 | ABZR86_RS08480 | | methylisocitrate lyase | 0.36 | ABZR86_RS15255 | | class 1 fructose-bisphosphatase | low | > 74 |
| Pseudomonas sp. S08-1 | 0.56 | OH686_01690 | | methylisocitrate lyase | 0.39 | OH686_10290 | | Fructose-1,6-bisphosphatase, type I | — | — |
| Rhodospirillum rubrum S1H | 0.34 | Rru_A2320 | | Ankyrin (NCBI) | 0.37 | Rru_A2403 | | Inositol phosphatase/fructose-1,6-bisphosphatase (NCBI) | low | > 58 |
| Rhodopseudomonas palustris CGA009 | 0.33 | TX73_012370 | | methylisocitrate lyase | 0.28 | TX73_024120 | | class 1 fructose-bisphosphatase | — | — |
| Xanthobacter sp. DMC5 | 0.32 | GFF2763 | | 2,3-dimethylmalate lyase | 0.30 | GFF1141 | | Fructose-1,6-bisphosphatase class 1 | — | — |
| Variovorax sp. OAS795 | 0.32 | ABID97_RS18835 | | oxaloacetate decarboxylase | 0.43 | ABID97_RS12875 | | class 1 fructose-bisphosphatase | low | > 91 |
| Azospirillum sp. SherDot2 | 0.31 | MPMX19_04657 | | 2,3-dimethylmalate lyase | 0.37 | MPMX19_02944 | | Fructose-1,6-bisphosphatase class 1 | low | > 112 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.30 | H281DRAFT_06209 | | carboxyvinyl-carboxyphosphonate phosphorylmutase | 0.42 | H281DRAFT_03991 | | D-fructose 1,6-bisphosphatase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.30 | GFF3032 | | Methylisocitrate lyase (EC 4.1.3.30) | 0.40 | GFF274 | | Fructose-1,6-bisphosphatase, type I (EC 3.1.3.11) | — | — |
| Dickeya dianthicola ME23 | 0.14 | DZA65_RS07470 | | phosphoenolpyruvate mutase | 0.76 | DZA65_RS19645 | | class 1 fructose-bisphosphatase | low | > 75 |
| Dickeya dianthicola 67-19 | 0.14 | HGI48_RS06990 | | phosphoenolpyruvate mutase | 0.76 | HGI48_RS18510 | | class 1 fructose-bisphosphatase | low | > 71 |
Not shown: 5 genomes with orthologs for CSW01_06735 only; 33 genomes with orthologs for CSW01_12885 only