Conservation of cofitness between CSW01_01465 and CSW01_10265 in Vibrio cholerae E7946 ATCC 55056

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01465 ketohydroxyglutarate aldolase 1.0 CSW01_10265 c-type cytochrome biogenesis protein CcmF 0.70 3
Pantoea sp. MT58 0.44 IAI47_08500 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.65 IAI47_06090 heme lyase CcmF/NrfE family subunit low > 76
Pantoea agglomerans CFBP13505 P0401 0.44 PagCFBP13505_RS02380 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.64 PagCFBP13505_RS00045 heme lyase CcmF/NrfE family subunit low > 74
Serratia liquefaciens MT49 0.44 IAI46_23180 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.65 IAI46_18085 heme lyase CcmF/NrfE family subunit 0.53 16
Shewanella oneidensis MR-1 0.44 SO2486 eda 2-deydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (NCBI ptt file) 0.49 SO0266 ccmF-1 cytochrome c-type biogenesis protein CcmF (NCBI ptt file) — —
Rahnella sp. WP5 0.43 EX31_RS10625 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.67 EX31_RS19745 heme lyase CcmF/NrfE family subunit low > 89
Pectobacterium carotovorum WPP14 0.43 HER17_RS11775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.63 HER17_RS09055 heme lyase CcmF/NrfE family subunit low > 75
Shewanella sp. ANA-3 0.43 Shewana3_2148 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.50 Shewana3_0234 cytochrome c-type biogenesis protein CcmF (RefSeq) — —
Shewanella loihica PV-4 0.43 Shew_2045 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.51 Shew_0193 cytochrome c-type biogenesis protein CcmF (RefSeq) — —
Shewanella amazonensis SB2B 0.42 Sama_1809 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (RefSeq) 0.51 Sama_0248 cytochrome c-type biogenesis protein CcmF (RefSeq) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.42 GFF1629 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.58 GFF4877 Cytochrome c heme lyase subunit CcmF — —
Alteromonas macleodii MIT1002 0.42 MIT1002_02403 KHG/KDPG aldolase 0.56 MIT1002_00965 Cytochrome c-type biogenesis protein CcmF — —
Phaeobacter inhibens DSM 17395 0.40 PGA1_c28010 KHG/KDPG aldolase 0.41 PGA1_c17010 cytochrome c-type biogenesis protein CcmF — —
Escherichia coli Nissle 1917 0.40 ECOLIN_RS10305 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 ECOLIN_RS12835 cytochrome c-type biogenesis heme lyase CcmF — —
Escherichia fergusonii Becca 0.40 EFB2_02093 KHG/KDPG aldolase 0.60 EFB2_01660 Cytochrome c-type biogenesis protein CcmF low > 86
Escherichia coli ECRC99 0.40 KEDOAH_01760 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 KEDOAH_04880 ccmF cytochrome c-type biogenesis heme lyase CcmF — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.40 OHPLBJKB_01879 KHG/KDPG aldolase 0.60 OHPLBJKB_01515 Cytochrome c-type biogenesis protein CcmF low > 74
Escherichia coli ECRC100 0.40 OKFHMN_26345 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 OKFHMN_23305 ccmF cytochrome c-type biogenesis heme lyase CcmF low > 79
Escherichia coli ECRC102 0.40 NIAGMN_01715 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 NIAGMN_21070 ccmF cytochrome c-type biogenesis heme lyase CcmF — —
Escherichia coli BL21 0.40 ECD_01821 KHG/KDPG aldolase; 2-dehydro-3-deoxy-phosphogluconate/4-hydroxy-2- oxoglutarate aldolase 0.60 ECD_02123 heme lyase, CcmF subunit — —
Escherichia coli ECOR38 0.40 HEPCGN_04750 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 HEPCGN_22570 ccmF cytochrome c-type biogenesis heme lyase CcmF low > 88
Escherichia coli ECRC101 0.40 MCAODC_19060 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 MCAODC_14355 ccmF cytochrome c-type biogenesis heme lyase CcmF low > 87
Escherichia coli BW25113 0.40 b1850 eda keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) 0.60 b2196 ccmF heme lyase, CcmF subunit (NCBI) low > 76
Marinobacter adhaerens HP15 0.40 HP15_2177 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 0.51 HP15_2281 cytochrome c assembly protein — —
Escherichia coli ECRC98 0.40 JDDGAC_00920 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 JDDGAC_27265 ccmF cytochrome c-type biogenesis heme lyase CcmF low > 87
Escherichia coli ECRC62 0.40 BNILDI_15650 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 BNILDI_13800 ccmF cytochrome c-type biogenesis heme lyase CcmF low > 75
Escherichia coli ECOR27 0.39 NOLOHH_16855 kdgA bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.60 NOLOHH_14880 ccmF cytochrome c-type biogenesis heme lyase CcmF low > 76
Pseudomonas stutzeri RCH2 0.39 Psest_0854 Entner-Doudoroff aldolase 0.51 Psest_1759 c-type cytochrome biogenesis protein CcmF — —
Klebsiella pneumoniae MKP103 0.38 KDGMDA_25360 keto-deoxy-phosphogluconate aldolase 0.62 KDGMDA_23845 cytochrome c maturation protein CcmE low > 95
Sinorhizobium meliloti 1021 0.38 SMc03153 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 0.42 SMc02363 cytochrome C-type biogenesis transmembrane protein low > 103
Pseudomonas aeruginosa MRSN321 0.38 DY961_RS01030 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.49 DY961_RS05510 heme lyase CcmF/NrfE family subunit — —
Pseudomonas aeruginosa PA14 0.38 IKLFDK_16165 keto-deoxy-phosphogluconate aldolase 0.49 IKLFDK_07040 Cytochrome c-type biogenesis protein CcmF — —
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_0356 Entner-Doudoroff aldolase 0.30 Ga0059261_0172 Cytochrome c biogenesis factor — —
Dyella japonica UNC79MFTsu3.2 0.37 ABZR86_RS14685 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.48 ABZR86_RS06445 heme lyase CcmF/NrfE family subunit — —
Pseudomonas aeruginosa PUPa3 0.37 DQ20_RS34505 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.49 DQ20_RS47280 heme lyase CcmF/NrfE family subunit — —
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_05150 keto-deoxy-phosphogluconate aldolase 0.52 AO356_03635 cytochrome C biogenesis protein CcmF — —
Sphingobium sp. HT1-2 0.37 GFF1595 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.36 GFF83 Cytochrome c heme lyase subunit CcmF — —
Pseudomonas fluorescens FW300-N2E2 0.36 Pf6N2E2_2883 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.51 Pf6N2E2_2555 Cytochrome c heme lyase subunit CcmF — —
Pseudomonas sp. RS175 0.36 PFR28_00575 2-dehydro-3-deoxy-phosphogluconate aldolase 0.52 PFR28_00870 Cytochrome c-type biogenesis protein CcmF — —
Xanthobacter sp. DMC5 0.36 GFF237 KHG/KDPG aldolase 0.41 GFF1779 Cytochrome c-type biogenesis protein CcmF — —
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.2446.1 hypothetical protein 0.47 Xcc-8004.3190.1 Cytochrome c heme lyase subunit CcmF — —
Pseudomonas lactucae CFBP13502 0.36 GEMAOFIL_04556 2-dehydro-3-deoxy-phosphogluconate aldolase 0.51 GEMAOFIL_01875 Cytochrome c-type biogenesis protein CcmF — —
Pseudomonas fluorescens FW300-N1B4 0.36 Pf1N1B4_587 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.51 Pf1N1B4_3644 Cytochrome c heme lyase subunit CcmF — —
Pseudomonas sp. SVBP6 0.36 COO64_RS04600 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.50 COO64_RS25715 heme lyase CcmF/NrfE family subunit — —
Rhodanobacter sp000427505 FW510-R12 0.36 LRK53_RS00660 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.45 LRK53_RS12730 heme lyase CcmF/NrfE family subunit — —
Pseudomonas sp. DMC3 0.36 GFF5138 2-dehydro-3-deoxy-phosphogluconate aldolase 0.51 GFF2490 Cytochrome c-type biogenesis protein CcmF — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1903 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) @ 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14) 0.53 PfGW456L13_4311 Cytochrome c heme lyase subunit CcmF — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_1122 2-keto-3-deoxy-phosphogluconate aldolase 0.52 Psyr_3388 Cytochrome c-type biogenesis protein CcmF — —
Pseudomonas fluorescens SBW25-INTG 0.35 PFLU_RS23715 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.51 PFLU_RS08670 heme lyase CcmF/NrfE family subunit — —
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_1122 2-keto-3-deoxy-phosphogluconate aldolase 0.52 Psyr_3388 Cytochrome c-type biogenesis protein CcmF — —
Pseudomonas orientalis W4I3 0.35 QF045_RS24235 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.51 QF045_RS11430 heme lyase CcmF/NrfE family subunit — —
Rhodanobacter denitrificans MT42 0.35 LRK55_RS07615 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.48 LRK55_RS15815 heme lyase CcmF/NrfE family subunit — —
Rhodanobacter denitrificans FW104-10B01 0.35 LRK54_RS07885 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.48 LRK54_RS16065 heme lyase CcmF/NrfE family subunit — —
Pseudomonas simiae WCS417 0.35 PS417_22100 keto-deoxy-phosphogluconate aldolase 0.52 PS417_08715 cytochrome C biogenesis protein CcmF — —
Pseudomonas fluorescens SBW25 0.35 PFLU_RS23715 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.51 PFLU_RS08670 heme lyase CcmF/NrfE family subunit — —
Pseudomonas sp. BP01 0.35 JOY50_RS11460 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.49 JOY50_RS00480 heme lyase CcmF/NrfE family subunit — —
Pseudomonas fluorescens FW300-N2E3 0.35 AO353_03350 keto-deoxy-phosphogluconate aldolase 0.51 AO353_18875 cytochrome C biogenesis protein CcmF — —
Pseudomonas putida KT2440 0.35 PP_1024 KHG/KDPG aldolase 0.50 PP_4322 holocytochrome c synthetase — —
Agrobacterium fabrum C58 0.35 Atu4494 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 0.44 Atu0975 cytochrome c-type synthesis protein — —
Rhodanobacter sp. FW510-T8 0.35 OKGIIK_14375 eda 2-keto-3-deoxy-6-phosphogluconate aldolase 0.46 OKGIIK_08585 ccmF c-type cytochrome biogenesis protein CcmF — —
Pseudomonas segetis P6 0.34 MPMX49_02829 2-dehydro-3-deoxy-phosphogluconate aldolase 0.55 MPMX49_03107 Cytochrome c-type biogenesis protein CcmF — —
Bosea sp. OAE506 0.34 ABIE41_RS23505 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.41 ABIE41_RS21455 heme lyase CcmF/NrfE family subunit — —
Rhizobium sp. OAE497 0.32 ABIE40_RS16720 2-dehydro-3-deoxy-phosphogluconate aldolase 0.43 ABIE40_RS05685 heme lyase CcmF/NrfE family subunit — —
Dinoroseobacter shibae DFL-12 0.31 Dshi_1768 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase (RefSeq) 0.44 Dshi_4051 cytochrome c-type biogenesis protein CcmF (RefSeq) — —
Lysobacter sp. OAE881 0.30 ABIE51_RS02890 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.48 ABIE51_RS08700 heme lyase CcmF/NrfE family subunit low > 62
Azospirillum brasilense Sp245 0.28 AZOBR_RS29850 ketohydroxyglutarate aldolase 0.45 AZOBR_RS00740 heme lyase subunit CcmF — —
Brevundimonas sp. GW460-12-10-14-LB2 0.23 A4249_RS10775 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase 0.34 A4249_RS10825 heme lyase CcmF/NrfE family subunit — —
Azospirillum sp. SherDot2 0.22 MPMX19_06076 KHG/KDPG aldolase 0.45 MPMX19_02533 Cytochrome c-type biogenesis protein CcmF — —
Caulobacter crescentus NA1000 Δfur 0.22 CCNA_01562 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase 0.38 CCNA_02848 heme chaperone-apocytochrome heme-lyase low > 67
Caulobacter crescentus NA1000 0.22 CCNA_01562 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxyphosphogluconate aldolase 0.38 CCNA_02848 heme chaperone-apocytochrome heme-lyase low > 66

Not shown: 38 genomes with orthologs for CSW01_01465 only; 9 genomes with orthologs for CSW01_10265 only