Conservation of cofitness between CSW01_02270 and CSW01_07490 in Vibrio cholerae E7946 ATCC 55056

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02270 malate dehydrogenase 1.0 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.63 3
Escherichia coli ECOR27 0.82 NOLOHH_09595 mdh malate dehydrogenase 0.72 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.74 23
Escherichia coli ECRC62 0.82 BNILDI_01940 mdh malate dehydrogenase 0.72 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.74 5
Escherichia coli ECRC98 0.82 JDDGAC_21420 mdh malate dehydrogenase 0.72 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase low > 87
Escherichia coli Nissle 1917 0.82 ECOLIN_RS18555 malate dehydrogenase 0.72 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli BL21 0.82 ECD_03096 malate dehydrogenase, NAD(P)-binding 0.72 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.43 20
Escherichia coli ECRC101 0.82 MCAODC_08315 mdh malate dehydrogenase 0.72 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.66 12
Escherichia coli BW25113 0.82 b3236 mdh malate dehydrogenase (NCBI) 0.72 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.54 56
Escherichia fergusonii Becca 0.82 EFB2_00594 Malate dehydrogenase 0.72 EFB2_03126 Dihydroorotate dehydrogenase (quinone) low > 86
Escherichia coli ECRC102 0.82 NIAGMN_15555 mdh malate dehydrogenase 0.72 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.82 24
Escherichia coli HS(pFamp)R (ATCC 700891) 0.82 OHPLBJKB_00468 Malate dehydrogenase 0.72 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) low > 74
Escherichia coli ECRC99 0.82 KEDOAH_10355 mdh malate dehydrogenase 0.72 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase — —
Escherichia coli ECRC100 0.82 OKFHMN_17795 mdh malate dehydrogenase 0.72 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase low > 79
Escherichia coli ECOR38 0.82 HEPCGN_16660 mdh malate dehydrogenase 0.72 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.43 56
Shewanella sp. ANA-3 0.81 Shewana3_3509 malate dehydrogenase (RefSeq) 0.65 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.79 33
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.81 GFF2149 Malate dehydrogenase (EC 1.1.1.37) 0.71 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) low > 78
Enterobacter asburiae PDN3 0.81 EX28DRAFT_3285 malate dehydrogenase (NAD) (EC 1.1.1.37) 0.73 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) — —
Enterobacter sp. TBS_079 0.81 MPMX20_04140 Malate dehydrogenase 0.73 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) low > 85
Klebsiella michiganensis M5al 0.81 BWI76_RS25420 malate dehydrogenase 0.71 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) low > 92
Klebsiella pneumoniae MKP103 0.81 KDGMDA_06200 malate dehydrogenase 0.72 KDGMDA_18145 quinone-dependent dihydroorotate dehydrogenase low > 95
Shewanella oneidensis MR-1 0.81 SO0770 mdh malate dehydrogenase (NCBI ptt file) 0.63 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.64 35
Shewanella amazonensis SB2B 0.80 Sama_0672 malate dehydrogenase (RefSeq) 0.64 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) low > 62
Pantoea agglomerans CFBP13505 P0401 0.80 PagCFBP13505_RS11115 malate dehydrogenase 0.74 PagCFBP13505_RS04625 quinone-dependent dihydroorotate dehydrogenase low > 74
Pectobacterium carotovorum WPP14 0.80 HER17_RS18390 malate dehydrogenase 0.72 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase low > 75
Pantoea sp. MT58 0.80 IAI47_02520 malate dehydrogenase 0.74 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase low > 76
Erwinia tracheiphila HP pepo 2.2 0.79 IJEDHG_13655 mdh malate dehydrogenase 0.73 IJEDHG_20465 pyrD quinone-dependent dihydroorotate dehydrogenase low > 61
Erwinia tracheiphila SCR3 0.79 LU632_RS21365 mdh malate dehydrogenase 0.73 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase low > 73
Shewanella loihica PV-4 0.79 Shew_0867 malate dehydrogenase (RefSeq) 0.64 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.65 55
Rahnella sp. WP5 0.79 EX31_RS08645 malate dehydrogenase 0.72 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase low > 89
Serratia liquefaciens MT49 0.79 IAI46_01825 malate dehydrogenase 0.72 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase low > 87
Dickeya dianthicola ME23 0.79 DZA65_RS03130 malate dehydrogenase 0.71 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase low > 75
Dickeya dadantii 3937 0.79 DDA3937_RS02970 malate dehydrogenase 0.71 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.79 HGI48_RS03135 malate dehydrogenase 0.70 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase low > 71
Erwinia amylovora T8 0.77 OLJFJH_06980 malate dehydrogenase 0.74 OLJFJH_15990 quinone-dependent dihydroorotate dehydrogenase low > 58
Alteromonas macleodii MIT1002 0.69 MIT1002_03492 Malate dehydrogenase 0.58 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) — —
Azospirillum brasilense Sp245 0.18 AZOBR_RS14060 malate dehydrogenase 0.38 AZOBR_RS13520 dihydroorotate dehydrogenase — —
Pedobacter sp. GW460-11-11-14-LB5 0.17 CA265_RS03080 malate dehydrogenase 0.45 CA265_RS14005 dihydroorotate dehydrogenase (quinone) — —
Rhodospirillum rubrum S1H 0.17 Rru_A1210 Malate dehydrogenase, NAD-dependent (NCBI) 0.38 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.17 CA264_13275 malate dehydrogenase 0.41 CA264_00865 dihydroorotate dehydrogenase (quinone) — —
Azospirillum sp. SherDot2 0.17 MPMX19_00107 Malate dehydrogenase 0.38 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) — —
Dinoroseobacter shibae DFL-12 0.17 Dshi_2876 malate dehydrogenase, NAD-dependent (RefSeq) 0.32 Dshi_0847 Dihydroorotate oxidase (RefSeq) — —
Magnetospirillum magneticum AMB-1 0.17 AMB_RS20025 malate dehydrogenase 0.38 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase — —
Sphingobium sp. HT1-2 0.16 GFF2450 Malate dehydrogenase (EC 1.1.1.37) 0.37 GFF977 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.16 Echvi_2076 malate dehydrogenase, NAD-dependent 0.43 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 — —
Phaeobacter inhibens DSM 17395 0.16 PGA1_c03650 malate dehydrogenase Mdh 0.34 PGA1_c12150 dihydroorotate dehydrogenase PyrD — —
Synechocystis sp000284455 PCC 6803 0.15 SGL_RS14885 malate dehydrogenase 0.35 SGL_RS17005 quinone-dependent dihydroorotate dehydrogenase — —
Sphingomonas koreensis DSMZ 15582 0.15 Ga0059261_1338 malate dehydrogenase (NAD) (EC 1.1.1.37) 0.40 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) — —
Bosea sp. OAE506 0.15 ABIE41_RS08960 malate dehydrogenase 0.36 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase — —
Rhodopseudomonas palustris CGA009 0.14 TX73_000995 malate dehydrogenase 0.39 TX73_004110 quinone-dependent dihydroorotate dehydrogenase — —
Xanthobacter sp. DMC5 0.14 GFF4411 Malate dehydrogenase 0.35 GFF4317 Dihydroorotate dehydrogenase (quinone) — —
Agrobacterium fabrum C58 0.14 Atu2639 putative malate dehydrogenase 0.41 Atu0486 dihydroorotate dehydrogenase — —
Bacteroides thetaiotaomicron VPI-5482 0.14 BT3911 malate dehydrogenase (NCBI ptt file) 0.24 BT1009 dihydroorotate dehydrogenase (NCBI ptt file) low > 81
Brevundimonas sp. GW460-12-10-14-LB2 0.14 A4249_RS12675 malate dehydrogenase 0.38 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase — —
Rhizobium sp. OAE497 0.14 ABIE40_RS18000 malate dehydrogenase 0.40 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase — —
Sinorhizobium meliloti 1021 0.13 SMc02479 malate dehydrogenase 0.42 SMc02245 dihydroorotate dehydrogenase 2 — —
Cellulophaga baltica 18 0.13 M666_RS00410 malate dehydrogenase 0.43 M666_RS19110 quinone-dependent dihydroorotate dehydrogenase — —
Caulobacter crescentus NA1000 0.13 CCNA_03770 malate dehydrogenase 0.35 CCNA_00562 dihydroorotate dehydrogenase — —
Caulobacter crescentus NA1000 Δfur 0.13 CCNA_03770 malate dehydrogenase 0.35 CCNA_00562 dihydroorotate dehydrogenase — —
Methanococcus maripaludis JJ 0.12 MMJJ_RS01675 malate dehydrogenase 0.13 MMJJ_RS02945 dihydroorotate dehydrogenase — —
Pseudomonas sp. BP01 0.12 JOY50_RS27245 malate dehydrogenase 0.56 JOY50_RS22105 quinone-dependent dihydroorotate dehydrogenase — —
Methanococcus maripaludis S2 0.11 MMP_RS03390 malate dehydrogenase 0.12 MMP_RS02330 dihydroorotate dehydrogenase — —
Acidovorax sp. GW101-3H11 0.11 Ac3H11_3153 Malate dehydrogenase (EC 1.1.1.37) 0.50 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Bifidobacterium breve UCC2003 0.10 BBR_RS16995 L-lactate dehydrogenase 0.21 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter sp000427505 FW510-R12 0.10 LRK53_RS09435 malate dehydrogenase 0.49 LRK53_RS12795 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. SCN45 0.10 GFF3901 Malate dehydrogenase (EC 1.1.1.37) 0.50 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) — —
Rhodanobacter denitrificans MT42 0.10 LRK55_RS00495 malate dehydrogenase 0.51 LRK55_RS15740 quinone-dependent dihydroorotate dehydrogenase — —
Rhodanobacter denitrificans FW104-10B01 0.10 LRK54_RS00720 malate dehydrogenase 0.50 LRK54_RS15985 quinone-dependent dihydroorotate dehydrogenase — —
Variovorax sp. OAS795 0.10 ABID97_RS08515 malate dehydrogenase 0.49 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.09 GFF3372 Malate dehydrogenase (EC 1.1.1.37) 0.49 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) — —
Rhodanobacter sp. FW510-T8 0.09 OKGIIK_06530 mdh malate dehydrogenase 0.50 OKGIIK_09010 pyrD quinone-dependent dihydroorotate dehydrogenase — —

Not shown: 4 genomes with orthologs for CSW01_02270 only; 47 genomes with orthologs for CSW01_07490 only