Conservation of cofitness between CSW01_04930 and CSW01_07190 in Vibrio cholerae E7946 ATCC 55056

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_04930 phosphoenolpyruvate-protein phosphotransferase PtsI 1.0 CSW01_07190 transcriptional regulator FNR 0.69 4
Rahnella sp. WP5 0.75 EX31_RS20185 phosphoenolpyruvate-protein phosphotransferase PtsI 0.86 EX31_RS07200 FNR family transcription factor low > 89
Klebsiella michiganensis M5al 0.74 BWI76_RS20650 phosphoenolpyruvate--protein phosphotransferase 0.85 BWI76_RS16185 transcriptional regulator FNR — —
Erwinia tracheiphila SCR3 0.74 LU632_RS06615 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.83 LU632_RS11420 FNR family transcription factor low > 73
Erwinia tracheiphila HP pepo 2.2 0.74 IJEDHG_17645 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.83 IJEDHG_23150 crp transcriptional regulator FNR low > 61
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.74 GFF2047 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) 0.85 GFF2656 Fumarate and nitrate reduction regulatory protein low > 78
Enterobacter asburiae PDN3 0.74 EX28DRAFT_0212 phosphoenolpyruvate-protein phosphotransferase 0.84 EX28DRAFT_1540 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases — —
Escherichia coli BW25113 0.73 b2416 ptsI PEP-protein phosphotransferase of PTS system (enzyme I) (NCBI) 0.85 b1334 fnr DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) — —
Klebsiella pneumoniae MKP103 0.73 KDGMDA_27495 phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 KDGMDA_21005 fumarate/nitrate reduction transcriptional regulator Fnr low > 95
Enterobacter sp. TBS_079 0.73 MPMX20_03310 Phosphoenolpyruvate-protein phosphotransferase 0.85 MPMX20_02035 Fumarate and nitrate reduction regulatory protein low > 85
Escherichia coli ECOR38 0.73 HEPCGN_21370 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 HEPCGN_25925 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 88
Escherichia coli ECRC102 0.73 NIAGMN_19960 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 NIAGMN_26410 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 80
Escherichia coli ECRC101 0.73 MCAODC_12720 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 MCAODC_16030 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 87
Escherichia coli ECRC62 0.73 BNILDI_12735 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 BNILDI_18090 fnr fumarate/nitrate reduction transcriptional regulator Fnr — —
Escherichia fergusonii Becca 0.73 EFB2_01460 Phosphoenolpyruvate-protein phosphotransferase 0.85 EFB2_02593 Fumarate and nitrate reduction regulatory protein — —
Escherichia coli ECRC100 0.73 OKFHMN_22190 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 OKFHMN_02240 fnr fumarate/nitrate reduction transcriptional regulator Fnr low > 79
Escherichia coli ECRC98 0.73 JDDGAC_26140 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 JDDGAC_04785 fnr fumarate/nitrate reduction transcriptional regulator Fnr — —
Escherichia coli ECRC99 0.73 KEDOAH_06030 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 KEDOAH_26530 fnr fumarate/nitrate reduction transcriptional regulator Fnr — —
Escherichia coli ECOR27 0.73 NOLOHH_13870 ptsI phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 NOLOHH_19940 fnr fumarate/nitrate reduction transcriptional regulator Fnr — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_01307 Phosphoenolpyruvate-protein phosphotransferase 0.85 OHPLBJKB_02348 Fumarate and nitrate reduction regulatory protein — —
Pectobacterium carotovorum WPP14 0.73 HER17_RS17180 phosphoenolpyruvate-protein phosphotransferase PtsI 0.86 HER17_RS10525 fumarate/nitrate reduction transcriptional regulator Fnr low > 75
Dickeya dadantii 3937 0.73 DDA3937_RS04480 phosphoenolpyruvate-protein phosphotransferase PtsI 0.86 DDA3937_RS10950 fumarate/nitrate reduction transcriptional regulator Fnr low > 74
Erwinia amylovora T8 0.73 OLJFJH_10855 phosphoenolpyruvate-protein phosphotransferase PtsI 0.83 OLJFJH_13925 transcriptional regulator FNR low > 58
Serratia liquefaciens MT49 0.73 IAI46_18460 phosphoenolpyruvate-protein phosphotransferase PtsI 0.86 IAI46_13260 FNR family transcription factor low > 87
Dickeya dianthicola ME23 0.73 DZA65_RS04355 phosphoenolpyruvate-protein phosphotransferase PtsI 0.86 DZA65_RS11360 fumarate/nitrate reduction transcriptional regulator Fnr 0.47 37
Dickeya dianthicola 67-19 0.73 HGI48_RS04440 phosphoenolpyruvate-protein phosphotransferase PtsI 0.86 HGI48_RS10900 fumarate/nitrate reduction transcriptional regulator Fnr low > 71
Pantoea agglomerans CFBP13505 P0401 0.73 PagCFBP13505_RS19970 phosphoenolpyruvate-protein phosphotransferase PtsI 0.86 PagCFBP13505_RS06575 fumarate/nitrate reduction transcriptional regulator Fnr low > 74
Pantoea sp. MT58 0.73 IAI47_05425 phosphoenolpyruvate-protein phosphotransferase PtsI 0.85 IAI47_09580 FNR family transcription factor 0.42 24
Desulfovibrio vulgaris Hildenborough JW710 0.35 DVU0829 ptsI phosphoenolpyruvate-protein phosphotransferase (TIGR) 0.14 DVU2547 transcriptional regulator, putative (TIGR) low > 55
Cupriavidus basilensis FW507-4G11 0.34 RR42_RS01795 phosphoenolpyruvate-protein phosphotransferase 0.40 RR42_RS12875 transcriptional regulator low > 128
Desulfovibrio vulgaris Miyazaki F 0.34 DvMF_2877 phosphoenolpyruvate-protein phosphotransferase (RefSeq) 0.14 DvMF_0993 transcriptional regulator, Crp/Fnr family (RefSeq) low > 51
Azospirillum brasilense Sp245 0.34 AZOBR_RS30470 phosphoenolpyruvate-protein phosphotransferase 0.26 AZOBR_RS01145 Crp/Fnr family transcriptional regulator 0.63 2
Burkholderia phytofirmans PsJN 0.33 BPHYT_RS02575 phosphoenolpyruvate-protein phosphotransferase 0.38 BPHYT_RS31300 Crp/Fnr family transcriptional regulator low > 109
Rhodospirillum rubrum S1H 0.32 Rru_A3445 Phosphoenolpyruvate-protein phosphotransferase (NCBI) 0.22 Rru_A3322 Transcriptional Regulator, Crp/Fnr family (NCBI) low > 58
Ralstonia solanacearum GMI1000 0.32 RS_RS01715 phosphoenolpyruvate--protein phosphotransferase 0.38 RS_RS06430 fumarate/nitrate reduction transcriptional regulator Fnr low > 80
Magnetospirillum magneticum AMB-1 0.32 AMB_RS22220 phosphoenolpyruvate--protein phosphotransferase 0.22 AMB_RS22105 transcriptional regulator low > 64
Herbaspirillum seropedicae SmR1 0.32 HSERO_RS00450 phosphoenolpyruvate-protein phosphotransferase 0.41 HSERO_RS16020 transcriptional regulator — —
Paraburkholderia graminis OAS925 0.32 ABIE53_000660 phosphotransferase system enzyme I (PtsI) 0.35 ABIE53_004332 CRP/FNR family transcriptional regulator low > 113
Paraburkholderia sabiae LMG 24235 0.32 QEN71_RS01430 phosphoenolpyruvate--protein phosphotransferase 0.38 QEN71_RS17975 helix-turn-helix domain-containing protein 0.65 52
Azospirillum sp. SherDot2 0.32 MPMX19_02625 Phosphoenolpyruvate-protein phosphotransferase 0.26 MPMX19_00212 Nitrogen fixation regulation protein FixK low > 112
Ralstonia sp. UNC404CL21Col 0.32 ABZR87_RS06725 phosphoenolpyruvate--protein phosphotransferase 0.39 ABZR87_RS11180 fumarate/nitrate reduction transcriptional regulator Fnr low > 80
Ralstonia solanacearum UW163 0.32 UW163_RS02705 phosphoenolpyruvate--protein phosphotransferase 0.38 UW163_RS13110 fumarate/nitrate reduction transcriptional regulator Fnr — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS10875 phosphoenolpyruvate--protein phosphotransferase 0.38 RALBFv3_RS15650 fumarate/nitrate reduction transcriptional regulator Fnr low > 76
Ralstonia solanacearum PSI07 0.32 RPSI07_RS22435 phosphoenolpyruvate--protein phosphotransferase 0.38 RPSI07_RS17705 fumarate/nitrate reduction transcriptional regulator Fnr low > 81
Xanthomonas campestris pv. campestris strain 8004 0.31 Xcc-8004.1655.1 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) 0.22 Xcc-8004.2952.1 transcriptional regulator, Crp/Fnr family low > 74
Dechlorosoma suillum PS 0.31 Dsui_0742 phosphoenolpyruvate-protein phosphotransferase 0.40 Dsui_1646 cAMP-binding protein low > 51
Methylophilus sp. DMC18 0.31 GFF2263 Phosphoenolpyruvate-protein phosphotransferase 0.38 GFF1089 Transcriptional activator protein Anr low > 43
Hydrogenophaga sp. GW460-11-11-14-LB1 0.31 GFF2931 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) 0.39 GFF4142 transcriptional regulator, Crp/Fnr family low > 90
Variovorax sp. SCN45 0.30 GFF3653 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) 0.22 GFF6947 transcriptional regulator, Crp/Fnr family low > 127
Shewanella sp. ANA-3 0.30 Shewana3_2257 phosphoenolpyruvate--protein phosphotransferase (RefSeq) 0.77 Shewana3_2115 fumarate/nitrate reduction transcriptional regulator (RefSeq) — —
Shewanella oneidensis MR-1 0.30 SO2237 ptsI phosphoenolpyruvate-protein phosphotransferase (NCBI ptt file) 0.76 SO2356 etrA electron transport regulator a (NCBI ptt file) low > 76
Castellaniella sp019104865 MT123 0.30 ABCV34_RS04780 phosphoenolpyruvate--protein phosphotransferase 0.34 ABCV34_RS06835 helix-turn-helix domain-containing protein low > 48
Acidovorax sp. GW101-3H11 0.30 Ac3H11_2115 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) 0.38 Ac3H11_975 transcriptional regulator, Crp/Fnr family — —
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS19785 phosphoenolpyruvate--protein phosphotransferase 0.25 ABZR86_RS04345 cyclic nucleotide-binding domain-containing protein low > 74
Rhodanobacter sp. FW510-T8 0.29 OKGIIK_02235 ptsP phosphoenolpyruvate--protein phosphotransferase 0.37 OKGIIK_00820 CRP-like protein Clp low > 53
Lysobacter sp. OAE881 0.29 ABIE51_RS16000 phosphoenolpyruvate--protein phosphotransferase 0.37 ABIE51_RS03805 fumarate/nitrate reduction transcriptional regulator Fnr low > 62
Rhodanobacter denitrificans FW104-10B01 0.29 LRK54_RS12845 phosphoenolpyruvate--protein phosphotransferase 0.35 LRK54_RS05830 helix-turn-helix domain-containing protein low > 59
Shewanella amazonensis SB2B 0.29 Sama_1650 phosphotransferase system, enzyme I (RefSeq) 0.76 Sama_1799 fumarate/nitrate reduction transcriptional regulator (RefSeq) low > 62
Rhodanobacter denitrificans MT42 0.29 LRK55_RS12545 phosphoenolpyruvate--protein phosphotransferase 0.35 LRK55_RS05585 helix-turn-helix domain-containing protein low > 63
Rhodanobacter sp000427505 FW510-R12 0.28 LRK53_RS15735 phosphoenolpyruvate--protein phosphotransferase 0.35 LRK53_RS14515 cyclic nucleotide-binding domain-containing protein — —
Shewanella loihica PV-4 0.28 Shew_1865 phosphoenolpyruvate-protein phosphotransferase (RefSeq) 0.76 Shew_1993 fumarate/nitrate reduction transcriptional regulator (RefSeq) — —

Not shown: 3 genomes with orthologs for CSW01_04930 only; 35 genomes with orthologs for CSW01_07190 only