Conservation of cofitness between CSW01_07180 and CSW01_06735 in Vibrio cholerae E7946 ATCC 55056

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_07180 tRNA 2-thiocytidine(32) synthetase TtcA 1.0 CSW01_06735 methylisocitrate lyase 0.61 7
Escherichia coli ECRC62 0.77 BNILDI_18020 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.62 BNILDI_23190 prpB methylisocitrate lyase low > 75
Escherichia coli ECRC99 0.77 KEDOAH_26600 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.61 KEDOAH_19065 prpB methylisocitrate lyase — —
Escherichia coli ECRC101 0.77 MCAODC_16100 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.61 MCAODC_28130 prpB methylisocitrate lyase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.77 OHPLBJKB_02337 tRNA-cytidine(32) 2-sulfurtransferase 0.62 OHPLBJKB_03339 2-methylisocitrate lyase low > 74
Escherichia coli Nissle 1917 0.77 ECOLIN_RS08065 tRNA 2-thiocytidine(32) synthetase TtcA 0.61 ECOLIN_RS02150 methylisocitrate lyase — —
Escherichia coli BL21 0.77 ECD_01321 tRNA s(2)C32 thioltransferase, iron sulfur cluster protein 0.62 ECD_00286 2-methylisocitrate lyase low > 61
Escherichia coli BW25113 0.77 b1344 ydaO predicted C32 tRNA thiolase (NCBI) 0.62 b0331 prpB 2-methylisocitrate lyase (NCBI) low > 76
Escherichia coli ECRC102 0.77 NIAGMN_26325 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.61 NIAGMN_06955 prpB methylisocitrate lyase low > 80
Escherichia coli ECOR27 0.77 NOLOHH_19870 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.62 NOLOHH_01775 prpB methylisocitrate lyase low > 76
Escherichia fergusonii Becca 0.76 EFB2_02583 tRNA-cytidine(32) 2-sulfurtransferase 0.62 EFB2_03706 2-methylisocitrate lyase low > 86
Escherichia coli ECRC100 0.76 OKFHMN_02155 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.61 OKFHMN_08900 prpB methylisocitrate lyase — —
Escherichia coli ECOR38 0.76 HEPCGN_26005 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.62 HEPCGN_07485 prpB methylisocitrate lyase low > 88
Escherichia coli ECRC98 0.76 JDDGAC_04715 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.61 JDDGAC_12555 prpB methylisocitrate lyase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.76 GFF2648 tRNA(Cytosine32)-2-thiocytidine synthetase 0.59 GFF4263 Methylisocitrate lyase (EC 4.1.3.30) low > 78
Dickeya dianthicola ME23 0.76 DZA65_RS12850 tRNA 2-thiocytidine(32) synthetase TtcA 0.14 DZA65_RS07470 phosphoenolpyruvate mutase low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS12410 tRNA 2-thiocytidine(32) synthetase TtcA 0.14 HGI48_RS06990 phosphoenolpyruvate mutase low > 71
Alteromonas macleodii MIT1002 0.72 MIT1002_02139 tRNA 2-thiocytidine biosynthesis protein TtcA 0.67 MIT1002_03129 Methylisocitrate lyase low > 70
Kangiella aquimarina DSM 16071 0.65 B158DRAFT_2154 tRNA s(2)C-32 sulfurtransferase (EC 2.8.1.4) 0.64 B158DRAFT_1343 methylisocitrate lyase 0.43 3
Pseudomonas sp. S08-1 0.64 OH686_05145 tRNA-(cytosine32)-2-thiocytidine synthetase TtcA 0.56 OH686_01690 methylisocitrate lyase low > 80
Pseudomonas stutzeri RCH2 0.64 Psest_3033 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control 0.63 Psest_2321 methylisocitrate lyase low > 67
Shewanella amazonensis SB2B 0.64 Sama_1801 hypothetical protein (RefSeq) 0.61 Sama_3294 prpB 2-methylisocitrate lyase (RefSeq) low > 62
Shewanella sp. ANA-3 0.64 Shewana3_2117 PP-loop domain-containing protein (RefSeq) 0.63 Shewana3_3825 prpB 2-methylisocitrate lyase (RefSeq) low > 73
Pseudomonas aeruginosa PA14 0.64 IKLFDK_05600 tRNA 2-thiocytidine(32) synthetase TtcA 0.65 IKLFDK_03445 methylisocitrate lyase low > 98
Pseudomonas aeruginosa PUPa3 0.64 DQ20_RS46340 ttcA;go_process=tRNA tRNA 2-thiocytidine(32) synthetase TtcA 0.65 DQ20_RS44335 prpB;go_function=methylisocitrate methylisocitrate lyase low > 101
Pseudomonas aeruginosa MRSN321 0.64 DY961_RS06455 ttcA;go_process=tRNA tRNA 2-thiocytidine(32) synthetase TtcA 0.65 DY961_RS08515 prpB;go_function=methylisocitrate methylisocitrate lyase low > 100
Marinobacter adhaerens HP15 0.64 HP15_2116 PP-loop domain protein 0.68 HP15_1932 methylisocitrate lyase 2 — —
Pseudomonas segetis P6 0.63 MPMX49_01806 tRNA-cytidine(32) 2-sulfurtransferase 0.62 MPMX49_02628 2-methylisocitrate lyase low > 75
Shewanella oneidensis MR-1 0.63 SO2354 conserved hypothetical protein (NCBI ptt file) 0.63 SO0345 prpB methylisocitrate lyase (NCBI ptt file) low > 76
Pseudomonas sp. DMC3 0.63 GFF4833 tRNA-cytidine(32) 2-sulfurtransferase 0.63 GFF5230 2-methylisocitrate lyase low > 89
Pseudomonas sp. RS175 0.63 PFR28_03236 tRNA-cytidine(32) 2-sulfurtransferase 0.64 PFR28_02928 2-methylisocitrate lyase low > 88
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS28595 tRNA 2-thiocytidine(32) synthetase TtcA 0.62 QEN71_RS17555 methylisocitrate lyase low > 153
Pseudomonas simiae WCS417 0.63 PS417_16415 tRNA 2-thiocytidine biosynthesis protein TtcA 0.63 PS417_21080 2-methylisocitrate lyase — —
Pseudomonas lactucae CFBP13502 0.63 GEMAOFIL_03610 tRNA-cytidine(32) 2-sulfurtransferase 0.62 GEMAOFIL_04361 2-methylisocitrate lyase low > 96
Pseudomonas sp. BP01 0.63 JOY50_RS23840 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.63 JOY50_RS25750 prpB methylisocitrate lyase low > 84
Pseudomonas putida KT2440 0.63 PP_1641 tRNA 2-thiocytidine biosynthesis protein TtcA 0.63 PP_2334 2-methylisocitrate lyase low > 96
Pseudomonas fluorescens GW456-L13 0.63 PfGW456L13_2020 tRNA(Cytosine32)-2-thiocytidine synthetase 0.63 PfGW456L13_4118 Methylisocitrate lyase (EC 4.1.3.30) low > 87
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_5711 tRNA(Cytosine32)-2-thiocytidine synthetase 0.63 Pf6N2E2_6061 Methylisocitrate lyase (EC 4.1.3.30) (from data) low > 103
Pseudomonas fluorescens FW300-N2E3 0.63 AO353_02780 tRNA 2-thiocytidine biosynthesis protein TtcA 0.64 AO353_00900 2-methylisocitrate lyase low > 101
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_3491 tRNA(Cytosine32)-2-thiocytidine synthetase 0.63 Pf1N1B4_3819 Methylisocitrate lyase (EC 4.1.3.30) low > 87
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_19000 tRNA 2-thiocytidine biosynthesis protein TtcA 0.64 AO356_20865 2-methylisocitrate lyase low > 104
Paraburkholderia bryophila 376MFSha3.1 0.62 H281DRAFT_05824 tRNA s(2)C-32 sulfurtransferase 0.30 H281DRAFT_06209 carboxyvinyl-carboxyphosphonate phosphorylmutase low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_3705 conserved hypothetical protein 0.62 Psyr_2085 methylisocitrate lyase low > 86
Pseudomonas sp. SVBP6 0.62 COO64_RS07395 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.63 COO64_RS09900 prpB methylisocitrate lyase low > 93
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_3705 conserved hypothetical protein 0.62 Psyr_2085 methylisocitrate lyase low > 86
Pseudomonas orientalis W4I3 0.62 QF045_RS18170 tRNA 2-thiocytidine(32) synthetase TtcA 0.63 QF045_RS22905 methylisocitrate lyase low > 93
Pseudomonas fluorescens SBW25-INTG 0.62 PFLU_RS18455 tRNA 2-thiocytidine(32) synthetase TtcA 0.62 PFLU_RS22690 methylisocitrate lyase low > 109
Pseudomonas fluorescens SBW25 0.62 PFLU_RS18455 tRNA 2-thiocytidine(32) synthetase TtcA 0.62 PFLU_RS22690 methylisocitrate lyase low > 109
Ralstonia sp. UNC404CL21Col 0.61 ABZR87_RS05700 tRNA 2-thiocytidine(32) synthetase TtcA 0.62 ABZR87_RS14590 methylisocitrate lyase low > 80
Ralstonia solanacearum PSI07 0.61 RPSI07_RS23130 tRNA 2-thiocytidine(32) synthetase TtcA 0.62 RPSI07_RS14645 methylisocitrate lyase low > 81
Shewanella loihica PV-4 0.61 Shew_1995 PP-loop domain-containing protein (RefSeq) 0.67 Shew_1820 prpB 2-methylisocitrate lyase (RefSeq) low > 60
Ralstonia solanacearum UW163 0.61 UW163_RS03335 tRNA 2-thiocytidine(32) synthetase TtcA 0.63 UW163_RS11055 methylisocitrate lyase — —
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS22035 tRNA 2-thiocytidine biosynthesis protein TtcA 0.63 HSERO_RS15660 2-methylisocitrate lyase — —
Ralstonia solanacearum IBSBF1503 0.61 RALBFv3_RS10245 tRNA 2-thiocytidine(32) synthetase TtcA 0.63 RALBFv3_RS02670 methylisocitrate lyase low > 76
Ralstonia solanacearum GMI1000 0.61 RS_RS00865 tRNA 2-thiocytidine(32) synthetase TtcA 0.62 RS_RS10050 methylisocitrate lyase low > 80
Dyella japonica UNC79MFTsu3.2 0.60 ABZR86_RS16485 tRNA 2-thiocytidine(32) synthetase TtcA 0.56 ABZR86_RS08480 methylisocitrate lyase low > 74
Cupriavidus basilensis FW507-4G11 0.60 RR42_RS01445 tRNA 2-thiocytidine biosynthesis protein TtcA 0.62 RR42_RS11260 Methylisocitrate lyase (EC 4.1.3.30) (from data) low > 128
Hydrogenophaga sp. GW460-11-11-14-LB1 0.60 GFF1658 tRNA(Cytosine32)-2-thiocytidine synthetase 0.30 GFF3032 Methylisocitrate lyase (EC 4.1.3.30) — —
Castellaniella sp019104865 MT123 0.59 ABCV34_RS10450 tRNA 2-thiocytidine(32) synthetase TtcA 0.58 ABCV34_RS01670 methylisocitrate lyase low > 48
Variovorax sp. OAS795 0.59 ABID97_RS06505 tRNA 2-thiocytidine(32) synthetase TtcA 0.32 ABID97_RS18835 oxaloacetate decarboxylase low > 91
Methylophilus sp. DMC18 0.58 GFF1541 tRNA-cytidine(32) 2-sulfurtransferase 0.62 GFF469 2-methylisocitrate lyase — —
Lysobacter sp. OAE881 0.58 ABIE51_RS01305 tRNA 2-thiocytidine(32) synthetase TtcA 0.57 ABIE51_RS06015 methylisocitrate lyase low > 62
Acinetobacter baumannii LAC-4 0.55 RR41_RS04315 tRNA 2-thiocytidine(32) synthetase TtcA 0.60 RR41_RS18485 methylisocitrate lyase low > 55
Rhodanobacter denitrificans MT42 0.55 LRK55_RS10320 tRNA 2-thiocytidine(32) synthetase TtcA 0.58 LRK55_RS00470 methylisocitrate lyase low > 63
Rhodanobacter denitrificans FW104-10B01 0.54 LRK54_RS10680 tRNA 2-thiocytidine(32) synthetase TtcA 0.58 LRK54_RS00695 methylisocitrate lyase low > 59
Acinetobacter radioresistens SK82 0.54 MPMX26_00810 tRNA-cytidine(32) 2-sulfurtransferase 0.60 MPMX26_01289 2-methylisocitrate lyase — —
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_13200 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.59 OKGIIK_06565 prpB methylisocitrate lyase low > 53
Xanthomonas campestris pv. campestris strain 8004 0.51 Xcc-8004.5211.1 tRNA(Cytosine32)-2-thiocytidine synthetase 0.58 Xcc-8004.3981.1 Methylisocitrate lyase (EC 4.1.3.30) low > 74
Dinoroseobacter shibae DFL-12 0.45 Dshi_0330 PP-loop domain protein (RefSeq) 0.29 Dshi_0689 isocitrate lyase family protein (RefSeq) 0.40 38

Not shown: 21 genomes with orthologs for CSW01_07180 only; 7 genomes with orthologs for CSW01_06735 only