Conservation of cofitness between CSW01_02450 and CSW01_01485 in Vibrio cholerae E7946 ATCC 55056

75 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02450 pyrroline-5-carboxylate reductase 1.0 CSW01_01485 transcriptional regulator 0.89 1
Serratia liquefaciens MT49 0.69 IAI46_21415 pyrroline-5-carboxylate reductase 0.54 IAI46_23965 gluconate operon transcriptional repressor GntR low > 87
Pectobacterium carotovorum WPP14 0.69 HER17_RS03805 pyrroline-5-carboxylate reductase 0.52 HER17_RS01450 gluconate operon transcriptional repressor GntR — —
Dickeya dadantii 3937 0.68 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.55 DDA3937_RS19785 gluconate operon transcriptional repressor GntR low > 74
Dickeya dianthicola 67-19 0.68 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.55 HGI48_RS19900 gluconate operon transcriptional repressor GntR — —
Dickeya dianthicola ME23 0.67 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.55 DZA65_RS20970 gluconate operon transcriptional repressor GntR — —
Rahnella sp. WP5 0.65 EX31_RS02690 pyrroline-5-carboxylate reductase 0.54 EX31_RS05060 gluconate operon transcriptional repressor GntR low > 89
Alteromonas macleodii MIT1002 0.60 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.31 MIT1002_03475 Gluconate utilization system GNT-I transcriptional repressor low > 70
Pseudomonas sp. BP01 0.37 JOY50_RS20905 proC pyrroline-5-carboxylate reductase 0.31 JOY50_RS23605 LacI family DNA-binding transcriptional regulator low > 84
Pseudomonas lactucae CFBP13502 0.37 GEMAOFIL_05483 Pyrroline-5-carboxylate reductase 0.34 GEMAOFIL_04536 HTH-type transcriptional regulator GntR — —
Pseudomonas orientalis W4I3 0.37 QF045_RS01130 pyrroline-5-carboxylate reductase 0.34 QF045_RS24095 LacI family DNA-binding transcriptional regulator low > 93
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.34 PFLU_RS23595 LacI family DNA-binding transcriptional regulator — —
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.34 PFLU_RS23595 LacI family DNA-binding transcriptional regulator — —
Pseudomonas putida KT2440 0.37 PP_5095 pyrroline-5-carboxylate reductase 0.31 PP_3415 Transcriptional regulator, LacI family low > 96
Pseudomonas sp. SVBP6 0.36 COO64_RS12995 proC pyrroline-5-carboxylate reductase 0.34 COO64_RS25590 LacI family DNA-binding transcriptional regulator — —
Pseudomonas simiae WCS417 0.36 PS417_26730 pyrroline-5-carboxylate reductase 0.33 PS417_21990 LacI family transcriptional regulator low > 88
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS26600 pyrroline-5-carboxylate reductase 0.29 QEN71_RS13585 LacI family DNA-binding transcriptional regulator low > 153
Pseudomonas segetis P6 0.36 ACVTMO_RS03015 proC pyrroline-5-carboxylate reductase 0.33 ACVTMO_RS11810 gntR HTH-type transcriptional regulator GntR — —
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.32 Psyr_3336 transcriptional regulator, LacI family — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.32 Psyr_3336 transcriptional regulator, LacI family low > 86
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13420 pyrroline-5-carboxylate reductase 0.34 AO356_05065 LacI family transcriptional regulator — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.33 AO353_03255 LacI family transcriptional regulator low > 101
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.34 PfGW456L13_1925 Gluconate utilization system Gnt-I transcriptional repressor low > 87
Paraburkholderia bryophila 376MFSha3.1 0.35 H281DRAFT_04679 pyrroline-5-carboxylate reductase 0.30 H281DRAFT_05920 transcriptional regulator, LacI family low > 103
Pseudomonas aeruginosa MRSN321 0.35 DY961_RS21945 proC;go_function=pyrroline-5-carboxylate pyrroline-5-carboxylate reductase 0.36 DY961_RS17990 gntR;inference=COORDINATES LacI family DNA-binding transcriptional regulator GntR low > 100
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.34 Pf6N2E2_2865 Gluconate utilization system Gnt-I transcriptional repressor — —
Pseudomonas aeruginosa PA14 0.35 IKLFDK_23455 pyrroline-5-carboxylate reductase 0.36 IKLFDK_11375 LacI family DNA-binding transcriptional regulator GntR low > 98
Pseudomonas aeruginosa PUPa3 0.35 DQ20_RS37355 proC;go_function=pyrroline-5-carboxylate pyrroline-5-carboxylate reductase 0.36 DQ20_RS59230 gntR;inference=COORDINATES LacI family DNA-binding transcriptional regulator GntR low > 101
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS03490 pyrroline-5-carboxylate reductase 0.32 BPHYT_RS00410 LacI family transcription regulator — —
Ralstonia sp. UNC404CL21Col 0.35 ABZR87_RS01230 pyrroline-5-carboxylate reductase 0.26 ABZR87_RS18255 LacI family DNA-binding transcriptional regulator — —
Pseudomonas sp. RS175 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase 0.34 PFR28_00593 HTH-type transcriptional regulator GntR — —
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.35 Pf1N1B4_558 Gluconate utilization system Gnt-I transcriptional repressor — —
Pseudomonas stutzeri RCH2 0.34 Psest_0283 pyrroline-5-carboxylate reductase 0.34 Psest_2126 Transcriptional regulators — —
Pseudomonas sp. DMC3 0.34 GFF210 Pyrroline-5-carboxylate reductase 0.33 GFF5268 HTH-type transcriptional regulator GntR — —
Ralstonia solanacearum GMI1000 0.33 RS_RS13440 pyrroline-5-carboxylate reductase 0.26 RS_RS24865 LacI family DNA-binding transcriptional regulator — —
Ralstonia solanacearum IBSBF1503 0.32 RALBFv3_RS05580 pyrroline-5-carboxylate reductase 0.24 RALBFv3_RS16125 GntR family transcriptional regulator low > 76
Ralstonia solanacearum UW163 0.32 UW163_RS08045 pyrroline-5-carboxylate reductase 0.24 UW163_RS16860 GntR family transcriptional regulator — —
Ralstonia solanacearum PSI07 0.32 RPSI07_RS11720 pyrroline-5-carboxylate reductase 0.26 RPSI07_RS07575 LacI family DNA-binding transcriptional regulator low > 81
Variovorax sp. OAS795 0.32 ABID97_RS01555 pyrroline-5-carboxylate reductase 0.29 ABID97_RS01205 LacI family DNA-binding transcriptional regulator — —
Castellaniella sp019104865 MT123 0.32 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.26 ABCV34_RS12285 LacI family DNA-binding transcriptional regulator low > 48
Acidovorax sp. GW101-3H11 0.32 Ac3H11_788 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.29 Ac3H11_3230 Gluconate utilization system Gnt-I transcriptional repressor — —
Variovorax sp. SCN45 0.31 GFF5553 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.30 GFF7257 KEGG: LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor — —
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS17360 pyrroline-5-carboxylate reductase 0.26 RR42_RS22645 GntR family transcriptional regulator — —
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS18990 pyrroline-5-carboxylate reductase 0.34 HSERO_RS05460 LacI family transcription regulator low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF2806 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.30 GFF5509 Gluconate utilization system Gnt-I transcriptional repressor 0.64 14
Enterobacter asburiae PDN3 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.51 EX28DRAFT_4274 transcriptional regulator, LacI family low > 76
Escherichia fergusonii Becca 0.27 EFB2_03670 Pyrroline-5-carboxylate reductase 0.52 EFB2_00382 HTH-type transcriptional regulator GntR low > 86
Enterobacter sp. TBS_079 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.52 MPMX20_04319 HTH-type transcriptional regulator GntR low > 85
Klebsiella pneumoniae MKP103 0.27 KDGMDA_14250 pyrroline-5-carboxylate reductase 0.51 KDGMDA_07120 gluconate operon transcriptional repressor GntR low > 95
Klebsiella michiganensis M5al 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.51 BWI76_RS26245 transcriptional regulator — —
Escherichia coli ECOR38 0.27 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.52 HEPCGN_15660 gntR gluconate operon transcriptional repressor GntR low > 88
Escherichia coli BL21 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.51 ECD_03289 d-gluconate inducible gluconate regulon transcriptional repressor low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.52 OHPLBJKB_00264 HTH-type transcriptional regulator GntR low > 74
Escherichia coli ECRC62 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.52 BNILDI_02870 gntR gluconate operon transcriptional repressor GntR low > 75
Escherichia coli BW25113 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.52 b3438 gntR DNA-binding transcriptional repressor (NCBI) low > 76
Escherichia coli Nissle 1917 0.27 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.52 ECOLIN_RS19675 gluconate operon transcriptional repressor GntR low > 55
Escherichia coli ECOR27 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.51 NOLOHH_08635 gntR gluconate operon transcriptional repressor GntR low > 76
Escherichia coli ECRC101 0.27 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.52 MCAODC_07365 gntR gluconate operon transcriptional repressor GntR low > 87
Escherichia coli ECRC99 0.27 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.52 KEDOAH_11305 gntR gluconate operon transcriptional repressor GntR — —
Escherichia coli ECRC100 0.27 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.52 OKFHMN_16835 gntR gluconate operon transcriptional repressor GntR low > 79
Escherichia coli ECRC102 0.27 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.52 NIAGMN_14605 gntR gluconate operon transcriptional repressor GntR low > 80
Escherichia coli ECRC98 0.27 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.52 JDDGAC_20465 gntR gluconate operon transcriptional repressor GntR low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.26 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.49 GFF570 Gluconate utilization system Gnt-I transcriptional repressor low > 78
Erwinia amylovora T8 0.26 OLJFJH_18285 pyrroline-5-carboxylate reductase 0.56 OLJFJH_04280 gluconate operon transcriptional repressor GntR — —
Pantoea sp. MT58 0.26 IAI47_14945 pyrroline-5-carboxylate reductase 0.52 IAI47_01650 gluconate operon transcriptional repressor GntR low > 76
Pantoea agglomerans CFBP13505 P0401 0.26 PagCFBP13505_RS10205 pyrroline-5-carboxylate reductase 0.50 PagCFBP13505_RS18155 gluconate operon transcriptional repressor GntR low > 74
Azospirillum sp. SherDot2 0.25 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.29 MPMX19_05332 HTH-type transcriptional regulator GntR — —
Agrobacterium fabrum C58 0.24 Atu2209 pyrroline-5-carboxylate reductase 0.28 Atu4685 LacI family transcriptional regulator low > 89
Sinorhizobium meliloti 1021 0.24 SMc02677 pyrroline-5-carboxylate reductase 0.29 SM_b20667 LacI family transcriptional regulator low > 103
Erwinia tracheiphila HP pepo 2.2 0.23 IJEDHG_26195 proC pyrroline-5-carboxylate reductase 0.54 IJEDHG_08040 gntR gluconate operon transcriptional repressor GntR — —
Erwinia tracheiphila SCR3 0.23 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.53 LU632_RS19160 gntR gluconate operon transcriptional repressor GntR low > 73
Azospirillum brasilense Sp245 0.23 AZOBR_RS06245 pyrroline-5-carboxylate reductase 0.31 AZOBR_RS15720 LacI family transcription regulator — —
Rhizobium sp. OAE497 0.23 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.25 ABIE40_RS04445 LacI family DNA-binding transcriptional regulator low > 107
Xanthobacter sp. DMC5 0.22 GFF1925 Pyrroline-5-carboxylate reductase 0.31 GFF1533 HTH-type transcriptional regulator GntR — —
Dinoroseobacter shibae DFL-12 0.20 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.27 Dshi_3322 transcriptional regulator, LacI family (RefSeq) — —
Phaeobacter inhibens DSM 17395 0.19 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.28 PGA1_c33870 putative HTH-type transcriptional regulator GntR low > 62

Not shown: 45 genomes with orthologs for CSW01_02450 only; 0 genomes with orthologs for CSW01_01485 only