Conservation of cofitness between BNILDI_14455 and BNILDI_21035 in Escherichia coli ECRC62

63 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC62 1.0 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 BNILDI_21035 bioF 8-amino-7-oxononanoate synthase 0.70 7
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 0.90 JDDGAC_10030 bioF 8-amino-7-oxononanoate synthase low > 86
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 0.90 MCAODC_25610 bioF 8-amino-7-oxononanoate synthase low > 87
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 0.90 NIAGMN_04440 bioF 8-amino-7-oxononanoate synthase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.91 ECOLIN_RS04135 8-amino-7-oxononanoate synthase — —
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 0.89 KEDOAH_21515 bioF 8-amino-7-oxononanoate synthase — —
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 0.90 OKFHMN_06395 bioF 8-amino-7-oxononanoate synthase low > 80
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 0.88 NOLOHH_22765 bioF 8-amino-7-oxononanoate synthase low > 75
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 0.90 b0776 bioF 8-amino-7-oxononanoate synthase (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 0.91 EFB2_03329 8-amino-7-oxononanoate synthase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 0.89 OHPLBJKB_02937 8-amino-7-oxononanoate synthase low > 73
Escherichia coli BL21 0.99 ECD_01980 multidrug efflux system, subunit B 0.89 ECD_00743 8-amino-7-oxononanoate synthase low > 61
Escherichia coli ECOR38 0.99 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 0.88 HEPCGN_01645 bioF 8-amino-7-oxononanoate synthase low > 87
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.65 BWI76_RS08765 8-amino-7-oxononanoate synthase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3854 Multidrug transporter MdtB 0.77 GFF672 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_03061 Multidrug resistance protein MdtB 0.69 MPMX20_01404 8-amino-7-oxononanoate synthase low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0483 Cation/multidrug efflux pump 0.70 EX28DRAFT_2215 8-amino-7-oxononanoate synthase low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.59 IAI46_06530 8-amino-7-oxononanoate synthase low > 86
Pantoea sp. MT58 0.80 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.57 IAI47_13525 8-amino-7-oxononanoate synthase low > 76
Erwinia tracheiphila SCR3 0.79 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.60 LU632_RS09135 bioF 8-amino-7-oxononanoate synthase — —
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.63 HER17_RS13455 8-amino-7-oxononanoate synthase low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.64 DDA3937_RS08515 8-amino-7-oxononanoate synthase low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.64 DZA65_RS08970 8-amino-7-oxononanoate synthase low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.63 HGI48_RS08680 8-amino-7-oxononanoate synthase low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.35 HSERO_RS12245 8-amino-7-oxononanoate synthase low > 78
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.30 RALBFv3_RS00820 8-amino-7-oxononanoate synthase low > 76
Ralstonia solanacearum UW163 0.65 UW163_RS21010 multidrug transporter subunit MdtB 0.30 UW163_RS14155 8-amino-7-oxononanoate synthase — —
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.29 RPSI07_RS16700 8-amino-7-oxononanoate synthase low > 81
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.31 RS_RS07435 8-amino-7-oxononanoate synthase low > 80
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.30 ABZR87_RS12340 8-amino-7-oxononanoate synthase low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.35 RR42_RS00930 8-amino-7-oxononanoate synthase low > 128
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.39 PFR28_04102 8-amino-7-oxononanoate synthase low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.36 AO356_14140 8-amino-7-oxononanoate synthase low > 104
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.60 EX31_RS23700 8-amino-7-oxononanoate synthase low > 89
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.37 PP_0363 8-amino-7-oxononanoate synthase low > 96
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.38 Pf6N2E2_4761 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 103
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.38 OH686_10350 8-amino-7-oxononanoate synthase 0.65 26
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.39 PfGW456L13_1148 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.38 AO353_07520 8-amino-7-oxononanoate synthase low > 101
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.39 PFLU_RS27645 8-amino-7-oxononanoate synthase low > 109
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.39 PFLU_RS27645 8-amino-7-oxononanoate synthase low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.39 PS417_26000 8-amino-7-oxononanoate synthase low > 88
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.39 Pf1N1B4_2488 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 87
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.35 QEN71_RS01095 8-amino-7-oxononanoate synthase — —
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.35 H281DRAFT_02095 8-amino-7-oxononanoate synthase low > 103
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.33 Ac3H11_3830 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 79
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.40 Psyr_4686 8-amino-7-oxononanoate synthase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.40 Psyr_4686 8-amino-7-oxononanoate synthase low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.39 Psest_0412 8-amino-7-oxononanoate synthase low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.36 BPHYT_RS02160 8-amino-7-oxononanoate synthase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.36 ABIE53_000579 8-amino-7-oxononanoate synthase low > 113
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.30 ABCV34_RS15295 8-amino-7-oxononanoate synthase low > 48
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.32 GFF144 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.36 GFF3995 8-amino-7-oxononanoate synthase (EC 2.3.1.47) low > 90
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.33 ABID97_RS16260 8-amino-7-oxononanoate synthase low > 91
Magnetospirillum magneticum AMB-1 0.52 AMB_RS17370 acriflavine resistance protein B 0.30 AMB_RS13875 8-amino-7-oxononanoate synthase — —
Rhodanobacter denitrificans MT42 0.50 LRK55_RS09505 efflux RND transporter permease subunit 0.35 LRK55_RS09895 8-amino-7-oxononanoate synthase low > 63
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS09845 efflux RND transporter permease subunit 0.36 LRK54_RS10255 8-amino-7-oxononanoate synthase low > 59
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS16320 efflux RND transporter permease subunit 0.35 ABZR86_RS15835 8-amino-7-oxononanoate synthase low > 74
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB 0.34 OKGIIK_13655 bioF 8-amino-7-oxononanoate synthase low > 52
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4792.1 Acriflavin resistance protein 0.33 Xcc-8004.504.1 8-amino-7-oxononanoate synthase (EC 2.3.1.47) 0.32 10
Bacteroides thetaiotaomicron VPI-5482 0.25 BT2252 multidrug efflux membrane fusion protein (NCBI ptt file) 0.27 BT1443 8-amino-7-oxononanoate synthase (NCBI ptt file) low > 81
Parabacteroides merdae CL09T00C40 0.24 HMPREF1078_RS05470 efflux RND transporter permease subunit 0.26 HMPREF1078_RS15290 8-amino-7-oxononanoate synthase 0.45 35
Phaeobacter inhibens DSM 17395 0.13 PGA1_78p00510 multidrug transporter MdtB 0.23 PGA1_c09130 8-amino-7-oxononanoate synthase BioF low > 62

Not shown: 2 genomes with orthologs for BNILDI_14455 only; 18 genomes with orthologs for BNILDI_21035 only