Conservation of cofitness between BNILDI_14455 and BNILDI_18390 in Escherichia coli ECRC62

63 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC62 1.0 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 BNILDI_18390 acnA aconitate hydratase AcnA 0.70 9
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_15690 acnA aconitate hydratase AcnA low > 87
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_26190 acnA aconitate hydratase AcnA — —
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NIAGMN_26745 acnA aconitate hydratase AcnA — —
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NOLOHH_20240 acnA aconitate hydratase AcnA low > 75
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.99 ECOLIN_RS07705 aconitate hydratase AcnA — —
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 OKFHMN_02575 acnA aconitate hydratase AcnA low > 80
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 JDDGAC_05120 acnA aconitate hydratase AcnA low > 86
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 0.99 EFB2_02649 Aconitate hydratase A low > 86
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b1276 acnA aconitate hydratase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_02406 Aconitate hydratase A low > 73
Escherichia coli BL21 0.99 ECD_01980 multidrug efflux system, subunit B 1.00 ECD_01253 aconitate hydratase 1; aconitase A low > 61
Escherichia coli ECOR38 0.99 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 HEPCGN_25625 acnA aconitate hydratase AcnA low > 87
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.88 BWI76_RS11940 aconitate hydratase 1 low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3854 Multidrug transporter MdtB 0.92 GFF2709 Aconitate hydratase (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_03061 Multidrug resistance protein MdtB 0.90 MPMX20_02499 Aconitate hydratase A low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0483 Cation/multidrug efflux pump 0.90 EX28DRAFT_0949 aconitate hydratase 1 low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.79 IAI46_13950 aconitate hydratase AcnA low > 86
Pantoea sp. MT58 0.80 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.80 IAI47_09250 aconitate hydratase AcnA low > 76
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.75 HER17_RS09315 aconitate hydratase AcnA low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.71 DDA3937_RS12555 aconitate hydratase AcnA low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.71 DZA65_RS13065 aconitate hydratase AcnA low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.70 HGI48_RS12610 aconitate hydratase AcnA low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.50 HSERO_RS14940 aconitate hydratase — —
Ralstonia solanacearum UW163 0.65 UW163_RS21010 multidrug transporter subunit MdtB 0.50 UW163_RS11035 aconitate hydratase AcnA — —
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.50 RALBFv3_RS02690 aconitate hydratase AcnA — —
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.50 RPSI07_RS14625 aconitate hydratase AcnA — —
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.50 ABZR87_RS14605 aconitate hydratase AcnA low > 80
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.50 RS_RS10065 aconitate hydratase AcnA low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.50 RR42_RS14490 aconitate hydratase low > 128
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.68 PFR28_01099 Aconitate hydratase A low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.69 AO356_02385 aconitate hydratase low > 104
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.69 Pf6N2E2_2301 Aconitate hydratase (EC 4.2.1.3) low > 103
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.68 PP_2112 aconitate hydratase 1 low > 96
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.77 EX31_RS09885 aconitate hydratase AcnA low > 89
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.67 OH686_02100 aconitate hydratase 1 low > 80
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.67 PfGW456L13_4052 Aconitate hydratase (EC 4.2.1.3) low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.67 AO353_00565 aconitate hydratase low > 101
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 PFLU_RS07595 aconitate hydratase AcnA low > 109
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 PFLU_RS07595 aconitate hydratase AcnA low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.68 PS417_07515 aconitate hydratase 0.23 35
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.67 Pf1N1B4_3888 Aconitate hydratase (EC 4.2.1.3) low > 87
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.49 QEN71_RS17535 aconitate hydratase AcnA low > 153
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.50 H281DRAFT_06606 aconitase — —
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.48 Ac3H11_1140 2-methylisocitrate dehydratase (EC 4.2.1.99) (from data) low > 79
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.68 Psyr_3404 aconitase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.68 Psyr_3404 aconitase low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.65 Psest_2521 aconitate hydratase 1 low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.49 BPHYT_RS33980 aconitate hydratase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.42 ABIE53_004758 aconitate hydratase — —
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.57 ABCV34_RS13800 aconitate hydratase AcnA low > 48
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.48 GFF3909 Aconitate hydratase (EC 4.2.1.3) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.50 GFF3382 Aconitate hydratase (EC 4.2.1.3) low > 90
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.49 ABID97_RS08550 aconitate hydratase AcnA low > 91
Azospirillum sp. SherDot2 0.53 MPMX19_05477 Multidrug resistance protein MdtB 0.65 MPMX19_02045 Aconitate hydratase A 0.45 47
Magnetospirillum magneticum AMB-1 0.52 AMB_RS17370 acriflavine resistance protein B 0.50 AMB_RS18485 aconitate hydratase AcnA low > 64
Rhodanobacter denitrificans MT42 0.50 LRK55_RS09505 efflux RND transporter permease subunit 0.56 LRK55_RS00560 aconitate hydratase AcnA — —
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS09845 efflux RND transporter permease subunit 0.56 LRK54_RS00785 aconitate hydratase AcnA — —
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS16320 efflux RND transporter permease subunit 0.56 ABZR86_RS02165 aconitate hydratase AcnA low > 74
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB 0.55 OKGIIK_06455 acnA aconitate hydratase AcnA — —
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4792.1 Acriflavin resistance protein 0.57 Xcc-8004.2894.1 Aconitate hydratase (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) low > 74
Rhodopseudomonas palustris CGA009 0.49 TX73_013310 efflux RND transporter permease subunit 0.61 TX73_001045 aconitate hydratase AcnA — —
Bacteroides thetaiotaomicron VPI-5482 0.25 BT2252 multidrug efflux membrane fusion protein (NCBI ptt file) 0.10 BT2072 aconitate hydratase (NCBI ptt file) low > 81
Phaeobacter inhibens DSM 17395 0.13 PGA1_78p00510 multidrug transporter MdtB 0.60 PGA1_c18830 aconitate hydratase AcnA — —

Not shown: 2 genomes with orthologs for BNILDI_14455 only; 31 genomes with orthologs for BNILDI_18390 only