Conservation of cofitness between Atu0486 and Atu0298 in Agrobacterium fabrum C58

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu0486 dihydroorotate dehydrogenase 1.0 Atu0298 orotidine 5 0.94 1
Sinorhizobium meliloti 1021 0.73 SMc02245 dihydroorotate dehydrogenase 2 0.75 SMc00412 orotidine 5'-phosphate decarboxylase 0.95 3
Rhizobium sp. OAE497 0.72 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.79 ABIE40_RS01345 orotidine-5'-phosphate decarboxylase — —
Azospirillum sp. SherDot2 0.45 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.26 MPMX19_02208 Orotidine 5'-phosphate decarboxylase — —
Azospirillum brasilense Sp245 0.45 AZOBR_RS13520 dihydroorotate dehydrogenase 0.29 AZOBR_RS03135 orotidine 5'-phosphate decarboxylase 0.43 66
Phaeobacter inhibens DSM 17395 0.45 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.36 PGA1_c32450 orotidine 5'-phosphate decarboxylase PyrF 0.96 4
Rhodopseudomonas palustris CGA009 0.45 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.51 TX73_001750 orotidine-5'-phosphate decarboxylase — —
Magnetospirillum magneticum AMB-1 0.42 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase 0.26 AMB_RS20255 orotidine-5'-phosphate decarboxylase — —
Dinoroseobacter shibae DFL-12 0.42 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.31 Dshi_0615 orotidine 5'-phosphate decarboxylase (RefSeq) 0.92 2
Sphingomonas koreensis DSMZ 15582 0.42 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.32 Ga0059261_0234 orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) — —
Rhodospirillum rubrum S1H 0.41 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.29 Rru_A3424 Orotidine-5'-phosphate decarboxylase (NCBI) 0.84 17
Caulobacter crescentus NA1000 Δfur 0.41 CCNA_00562 dihydroorotate dehydrogenase 0.44 CCNA_00104 orotidine 5'-phosphate decarboxylase 0.79 3
Caulobacter crescentus NA1000 0.41 CCNA_00562 dihydroorotate dehydrogenase 0.44 CCNA_00104 orotidine 5'-phosphate decarboxylase 0.97 2
Brevundimonas sp. GW460-12-10-14-LB2 0.41 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.37 A4249_RS14665 orotidine-5'-phosphate decarboxylase — —
Bosea sp. OAE506 0.41 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.53 ABIE41_RS00050 orotidine-5'-phosphate decarboxylase 0.87 1
Pantoea sp. MT58 0.40 IAI47_12705 quinone-dependent dihydroorotate dehydrogenase 0.30 IAI47_09275 orotidine-5'-phosphate decarboxylase 0.97 9
Acinetobacter radioresistens SK82 0.40 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.30 MPMX26_01242 Orotidine 5'-phosphate decarboxylase 0.99 1
Pectobacterium carotovorum WPP14 0.39 HER17_RS12005 quinone-dependent dihydroorotate dehydrogenase 0.30 HER17_RS09390 orotidine-5'-phosphate decarboxylase 0.97 13
Alteromonas macleodii MIT1002 0.39 MIT1002_02035 Dihydroorotate dehydrogenase (quinone) 0.36 MIT1002_02184 Orotidine 5'-phosphate decarboxylase 0.83 10
Dickeya dadantii 3937 0.39 DDA3937_RS12855 quinone-dependent dihydroorotate dehydrogenase 0.31 DDA3937_RS12525 orotidine-5'-phosphate decarboxylase 0.80 8
Pseudomonas stutzeri RCH2 0.39 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.28 Psest_1714 orotidine 5'-phosphate decarboxylase, subfamily 1 — —
Vibrio cholerae E7946 ATCC 55056 0.39 CSW01_07490 dihydroorotate dehydrogenase (quinone) 0.33 CSW01_09560 orotidine-5'-phosphate decarboxylase 0.62 8
Pseudomonas simiae WCS417 0.39 PS417_20935 dihydroorotate dehydrogenase 0.29 PS417_09055 orotidine 5'-phosphate decarboxylase — —
Pseudomonas putida KT2440 0.39 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.30 PP_1815 Orotidine 5'-phosphate decarboxylase — —
Pseudomonas fluorescens SBW25-INTG 0.39 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.30 PFLU_RS09110 orotidine-5'-phosphate decarboxylase — —
Pseudomonas fluorescens SBW25 0.39 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.30 PFLU_RS09110 orotidine-5'-phosphate decarboxylase — —
Pseudomonas fluorescens FW300-N2E3 0.39 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.31 AO353_01670 orotidine 5'-phosphate decarboxylase — —
Dickeya dianthicola ME23 0.39 DZA65_RS13390 quinone-dependent dihydroorotate dehydrogenase 0.30 DZA65_RS13030 orotidine-5'-phosphate decarboxylase 0.95 2
Shewanella sp. ANA-3 0.39 Shewana3_1786 dihydroorotate dehydrogenase 2 (RefSeq) 0.32 Shewana3_1981 orotidine 5'-phosphate decarboxylase (RefSeq) 0.94 4
Shewanella loihica PV-4 0.39 Shew_1810 dihydroorotate dehydrogenase 2 (RefSeq) 0.30 Shew_1958 orotidine 5'-phosphate decarboxylase (RefSeq) — —
Rahnella sp. WP5 0.38 EX31_RS18095 quinone-dependent dihydroorotate dehydrogenase 0.29 EX31_RS09855 orotidine-5'-phosphate decarboxylase 0.93 33
Pseudomonas fluorescens FW300-N1B4 0.38 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.29 Pf1N1B4_514 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) — —
Klebsiella michiganensis M5al 0.38 BWI76_RS09910 dihydroorotate dehydrogenase (quinone) 0.29 BWI76_RS11965 orotidine-5'-phosphate decarboxylase 0.86 4
Dickeya dianthicola 67-19 0.38 HGI48_RS12925 quinone-dependent dihydroorotate dehydrogenase 0.30 HGI48_RS12580 orotidine-5'-phosphate decarboxylase 0.85 6
Pseudomonas syringae pv. syringae B728a ΔmexB 0.38 Psyr_2106 dihydroorotate oxidase A 0.29 Psyr_1836 orotidine-5'-phosphate decarboxylase — —
Pseudomonas syringae pv. syringae B728a 0.38 Psyr_2106 dihydroorotate oxidase A 0.29 Psyr_1836 orotidine-5'-phosphate decarboxylase — —
Pseudomonas fluorescens GW456-L13 0.38 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.31 PfGW456L13_2056 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) — —
Pseudomonas fluorescens FW300-N2C3 0.38 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.29 AO356_19850 orotidine 5'-phosphate decarboxylase — —
Shewanella amazonensis SB2B 0.38 Sama_1593 dihydroorotate dehydrogenase 2 (RefSeq) 0.31 Sama_1740 orotidine 5'-phosphate decarboxylase (RefSeq) 0.83 4
Serratia liquefaciens MT49 0.38 IAI46_08805 quinone-dependent dihydroorotate dehydrogenase 0.28 IAI46_13915 orotidine-5'-phosphate decarboxylase 0.81 18
Pseudomonas fluorescens FW300-N2E2 0.38 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.29 Pf6N2E2_5887 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) — —
Pseudomonas sp. S08-1 0.38 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.28 OH686_00580 Orotidine 5'-phosphate decarboxylase — —
Marinobacter adhaerens HP15 0.38 HP15_1377 dihydroorotate dehydrogenase 0.32 HP15_1370 orotidine 5'-phosphate decarboxylase — —
Shewanella oneidensis MR-1 0.38 SO2592 pyrD dihydroorotate dehydrogenase (NCBI ptt file) 0.31 SO2398 pyrF orotidine 5`-phosphate decarboxylase (NCBI ptt file) 0.96 3
Escherichia fergusonii Becca 0.38 EFB2_03126 Dihydroorotate dehydrogenase (quinone) 0.29 EFB2_02644 Orotidine 5'-phosphate decarboxylase low > 86
Pseudomonas sp. RS175 0.38 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.29 PFR28_03064 'Orotidine 5'-phosphate decarboxylase' transl_table=11 — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.38 GFF3236 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.27 GFF2704 'Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)' transl_table=11 low > 78
Escherichia coli ECOR38 0.38 HEPCGN_23225 pyrD quinone-dependent dihydroorotate dehydrogenase 0.29 HEPCGN_25650 pyrF orotidine-5'-phosphate decarboxylase low > 85
Escherichia coli Nissle 1917 0.38 ECOLIN_RS04965 quinone-dependent dihydroorotate dehydrogenase 0.28 ECOLIN_RS07730 orotidine-5'-phosphate decarboxylase — —
Escherichia coli ECRC102 0.37 NIAGMN_03015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.29 NIAGMN_26720 pyrF orotidine-5'-phosphate decarboxylase — —
Escherichia coli ECRC99 0.37 KEDOAH_22440 pyrD quinone-dependent dihydroorotate dehydrogenase 0.29 KEDOAH_26215 pyrF orotidine-5'-phosphate decarboxylase — —
Escherichia coli ECRC101 0.37 MCAODC_24685 pyrD quinone-dependent dihydroorotate dehydrogenase 0.29 MCAODC_15715 pyrF orotidine-5'-phosphate decarboxylase — —
Escherichia coli BW25113 0.37 b0945 pyrD dihydroorotate dehydrogenase (NCBI) 0.30 b1281 pyrF orotidine 5'-phosphate decarboxylase (NCBI) 0.94 3
Escherichia coli ECRC62 0.37 BNILDI_20015 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 BNILDI_18365 pyrF orotidine-5'-phosphate decarboxylase — —
Escherichia coli ECRC98 0.37 JDDGAC_08905 pyrD quinone-dependent dihydroorotate dehydrogenase 0.29 JDDGAC_05095 pyrF orotidine-5'-phosphate decarboxylase — —
Escherichia coli BL21 0.37 ECD_00949 dihydro-orotate oxidase, FMN-linked 0.30 ECD_01258 orotidine-5'-phosphate decarboxylase 0.72 34
Escherichia coli ECOR27 0.37 NOLOHH_21850 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 NOLOHH_20215 pyrF orotidine-5'-phosphate decarboxylase low > 57
Escherichia coli ECRC101 0.37 OKFHMN_05295 pyrD quinone-dependent dihydroorotate dehydrogenase 0.29 OKFHMN_02550 pyrF orotidine-5'-phosphate decarboxylase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.37 OHPLBJKB_02721 Dihydroorotate dehydrogenase (quinone) 0.30 OHPLBJKB_02401 'Orotidine 5'-phosphate decarboxylase' transl_table=11 0.71 5
Enterobacter asburiae PDN3 0.37 EX28DRAFT_1998 dihydroorotate oxidase A (EC 1.3.3.1) 0.29 EX28DRAFT_0954 orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) — —
Enterobacter sp. TBS_079 0.37 MPMX20_01596 Dihydroorotate dehydrogenase (quinone) 0.28 MPMX20_02494 Orotidine 5'-phosphate decarboxylase 0.97 2
Kangiella aquimarina DSM 16071 0.36 B158DRAFT_2228 dihydroorotate oxidase A (EC 1.3.3.1) 0.35 B158DRAFT_2331 orotidine-5'-phosphate decarboxylase (EC 4.1.1.23) — —
Erwinia tracheiphila SCR3 0.36 LU632_RS09955 pyrD quinone-dependent dihydroorotate dehydrogenase 0.30 LU632_RS12500 pyrF orotidine-5'-phosphate decarboxylase 0.94 5
Xanthomonas campestris pv. campestris strain 8004 0.36 Xcc-8004.3032.1 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.29 Xcc-8004.5259.1 Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23) — —
Fusobacterium nucleatum SB010 0.08 HUW76_08740 dihydroorotate dehydrogenase 0.29 HUW76_08730 orotidine-5'-phosphate decarboxylase 0.99 4
Desulfovibrio vulgaris Hildenborough JW710 0.08 DVU3316 pyrD dihydroorotate dehydrogenase (TIGR) 0.24 DVU0901 pyrF orotidine 5`-phosphate decarboxylase (TIGR) — —
Desulfovibrio vulgaris Miyazaki F 0.07 DvMF_2143 dihydroorotate dehydrogenase family protein (RefSeq) 0.26 DvMF_1137 orotidine 5'-phosphate decarboxylase (RefSeq) 0.92 3

Not shown: 31 genomes with orthologs for Atu0486 only; 1 genomes with orthologs for Atu0298 only