Homologs of Synpcc7942_1377 from Synechococcus elongatus PCC 7942

metal dependent phosphohydrolase
SEED: GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
KEGG: guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Synechococcus elongatus PCC 7942 Synpcc7942_1377 metal dependent phosphohydrolase strong 100 100
o Desulfovibrio vulgaris Hildenborough JW710 DVU2083 relA GTP pyrophosphokinase (TIGR) sig. 42 92
o Mycobacterium tuberculosis H37Rv Rv2583c Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase) strong 42 93
o Desulfovibrio vulgaris Miyazaki F DvMF_0787 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) strong 43 92
o Shewanella oneidensis MR-1 SO0359 spoT guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) strong 42 91
o Shewanella sp. ANA-3 Shewana3_3812 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) strong 42 91
o Bifidobacterium breve UCC2003 BBR_RS16410 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase no data 40 93
o Enterobacter asburiae PDN3 EX28DRAFT_3899 (p)ppGpp synthetase, RelA/SpoT family sig. 41 91
o Enterobacter sp. TBS_079 MPMX20_00086 Bifunctional (p)ppGpp synthase/hydrolase SpoT strong 41 91
o Shewanella amazonensis SB2B Sama_0264 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) strong 41 92
o Shewanella loihica PV-4 Shew_3499 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) strong 40 91
o Klebsiella michiganensis M5al BWI76_RS27430 (p)ppGpp synthetase strong 41 91
o Escherichia fergusonii Becca EFB2_00138 Bifunctional (p)ppGpp synthase/hydrolase SpoT insig. 40 91
o Escherichia coli ECOR27 NOLOHH_07435 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 40 91
o Escherichia coli ECOR38 HEPCGN_14375 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase cofit 40 91
o Escherichia coli ECRC101 OKFHMN_15555 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase insig. 40 91
o Escherichia coli ECRC101 MCAODC_06065 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase insig. 40 91
o Escherichia coli ECRC102 NIAGMN_13315 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase insig. 40 91
o Escherichia coli ECRC62 BNILDI_04080 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase insig. 40 91
o Escherichia coli ECRC98 JDDGAC_19180 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 40 91
o Escherichia coli ECRC99 KEDOAH_12590 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 40 91
o Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_00051 Bifunctional (p)ppGpp synthase/hydrolase SpoT cofit 40 91
o Escherichia coli Nissle 1917 ECOLIN_RS20790 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase strong 40 91
o Escherichia coli BW25113 b3650 spoT bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) strong 40 91
o Escherichia coli BL21 ECD_03507 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase sig. 40 91
o Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF357 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 strong 40 91
o Kangiella aquimarina DSM 16071 B158DRAFT_0574 (p)ppGpp synthetase, RelA/SpoT family no data 42 91
o Pantoea sp. MT58 IAI47_00510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase sig. 41 91
o Dickeya dianthicola ME23 DZA65_RS22150 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 41 91
o Dickeya dianthicola 67-19 HGI48_RS21180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 41 91
o Vibrio cholerae E7946 ATCC 55056 CSW01_13675 bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase insig. 40 91
o Erwinia tracheiphila SCR3 LU632_RS22200 spoT bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase insig. 40 91
o Alteromonas macleodii MIT1002 MIT1002_00108 Bifunctional (p)ppGpp synthase/hydrolase SpoT strong 40 92
o Rahnella sp. WP5 EX31_RS15810 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase sig. 40 91
o Serratia liquefaciens MT49 IAI46_24895 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase insig. 40 91
o Pectobacterium carotovorum WPP14 HER17_RS21385 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase cofit 40 91
o Pseudomonas sp. S08-1 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I cofit 38 96
o Fusobacterium nucleatum SB010 HUW76_09030 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase strong 39 91
o Pseudomonas fluorescens FW300-N2C3 AO356_19060 (p)ppGpp synthetase strong 39 95
o Dickeya dadantii 3937 DDA3937_RS00180 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 41 91
o Pseudomonas sp. RS175 PFR28_03223 GTP pyrophosphokinase strong 39 95
o Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) strong 39 95
o Pseudomonas putida KT2440 PP_5302 bifunctional (p)ppGpp synthase/hydrolase no data 40 92
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_4361 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) no data 40 92
o Azospirillum brasilense Sp245 AZOBR_RS22045 GTP pyrophosphokinase insig. 41 89
  Pseudomonas sp. S08-1 OH686_13550 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II insig. 40 92
o Pseudomonas stutzeri RCH2 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family strong 40 88
  Pseudomonas sp. RS175 PFR28_04424 Bifunctional (p)ppGpp synthase/hydrolase SpoT no data 40 92
o Pseudomonas fluorescens GW456-L13 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) strong 38 95
o Castellaniella sp019104865 MT123 ABCV34_RS03095 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase no data 39 91
  Pseudomonas fluorescens FW300-N2C3 AO356_12480 (p)ppGpp synthetase no data 40 92
o Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) strong 38 95
o Pseudomonas simiae WCS417 PS417_20150 (p)ppGpp synthetase no data 39 95
o Pseudomonas fluorescens FW300-N2E3 AO353_09280 (p)ppGpp synthetase no data 39 92
o Pseudomonas syringae pv. syringae B728a Psyr_3695 RelA/SpoT protein strong 38 96
o Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_3695 RelA/SpoT protein strong 38 96
  Pseudomonas fluorescens GW456-L13 PfGW456L13_780 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) no data 40 92
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_2113 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) no data 39 92
  Pseudomonas putida KT2440 PP_1656 ATP:GTP 3'-pyrophosphotransferase strong 38 95
  Pseudomonas syringae pv. syringae B728a Psyr_0209 RelA/SpoT protein no data 40 92
  Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_0209 RelA/SpoT protein no data 40 92
o Azospirillum sp. SherDot2 MPMX19_00838 GTP pyrophosphokinase rsh sig. 39 92
o Pseudomonas fluorescens SBW25 PFLU_RS22095 GTP diphosphokinase strong 38 95
o Pseudomonas fluorescens SBW25-INTG PFLU_RS22095 GTP diphosphokinase strong 38 95
  Pseudomonas fluorescens SBW25 PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 39 92
  Pseudomonas fluorescens SBW25-INTG PFLU_RS29510 bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase no data 39 92
  Pseudomonas simiae WCS417 PS417_27830 (p)ppGpp synthetase no data 39 92
o Dechlorosoma suillum PS Dsui_0500 (p)ppGpp synthetase, RelA/SpoT family strong 38 91
  Pseudomonas fluorescens FW300-N2E3 AO353_02710 (p)ppGpp synthetase strong 38 95
  Pseudomonas stutzeri RCH2 Psest_3817 (p)ppGpp synthetase, RelA/SpoT family no data 40 92
  Dickeya dianthicola ME23 DZA65_RS18145 GTP diphosphokinase sig. 38 91
  Dickeya dianthicola 67-19 HGI48_RS17070 GTP diphosphokinase cofit 40 86
  Pantoea sp. MT58 IAI47_04120 GTP diphosphokinase strong 39 86
  Dickeya dadantii 3937 DDA3937_RS17015 GTP diphosphokinase strong 40 86
o Herbaspirillum seropedicae SmR1 HSERO_RS10635 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase no data 38 97
  Erwinia tracheiphila SCR3 LU632_RS06350 relA GTP diphosphokinase cofit 37 97
  Rahnella sp. WP5 EX31_RS07955 GTP diphosphokinase strong 37 97
  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 strong 37 91
  Vibrio cholerae E7946 ATCC 55056 CSW01_12405 GTP diphosphokinase insig. 40 86
  Enterobacter asburiae PDN3 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family strong 38 91
  Shewanella amazonensis SB2B Sama_1033 GTP diphosphokinase (RefSeq) strong 40 86
  Pectobacterium carotovorum WPP14 HER17_RS04115 GTP diphosphokinase strong 37 97
  Enterobacter sp. TBS_079 MPMX20_03653 GTP pyrophosphokinase strong 39 88
  Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_00947 GTP pyrophosphokinase cofit 37 93
  Escherichia coli BL21 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase strong 37 92
  Escherichia coli ECOR27 NOLOHH_12125 relA GTP diphosphokinase cofit 37 92
  Escherichia coli ECOR38 HEPCGN_19500 relA GTP diphosphokinase insig. 37 92
  Escherichia coli ECRC101 OKFHMN_20250 relA GTP diphosphokinase insig. 37 92
  Escherichia coli ECRC101 MCAODC_10775 relA GTP diphosphokinase insig. 37 92
  Escherichia coli ECRC102 NIAGMN_18020 relA GTP diphosphokinase insig. 37 92
  Escherichia coli ECRC62 BNILDI_10630 relA GTP diphosphokinase insig. 37 92
  Escherichia coli ECRC98 JDDGAC_23915 relA GTP diphosphokinase no data 37 92
  Escherichia coli ECRC99 KEDOAH_07880 relA GTP diphosphokinase no data 37 92
  Escherichia coli Nissle 1917 ECOLIN_RS15515 GTP diphosphokinase cofit 37 92
  Escherichia coli BW25113 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) strong 37 92
o Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_04004 (p)ppGpp synthetase I, SpoT/RelA strong 37 96
o Burkholderia phytofirmans PsJN BPHYT_RS15305 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase strong 36 96
  Klebsiella michiganensis M5al BWI76_RS22805 GTP diphosphokinase strong 39 86
  Shewanella oneidensis MR-1 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) strong 39 89
  Escherichia fergusonii Becca EFB2_01133 GTP pyrophosphokinase strong 37 92