Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Cupriavidus basilensis FW507-4G11 | RR42_RS27825 | | 4-hydroxyphenylacetate isomerase | insig. | 100 | 100 |
o | Ralstonia sp. UNC404CL21Col | ABZR87_RS13535 | | fumarylacetoacetate hydrolase family protein | insig. | 58 | 90 |
o | Paraburkholderia sabiae LMG 24235 | QEN71_RS34375 | | fumarylacetoacetate hydrolase family protein | insig. | 49 | 89 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS12025 | | fumarylacetoacetate hydrolase family protein | insig. | 54 | 81 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03258 | | 5-carboxy-2-oxohept-3-enedioate decarboxylase HpaG1 subunit (EC 4.1.1.68) | insig. | 51 | 84 |
| Burkholderia phytofirmans PsJN | BPHYT_RS28875 | | 5-oxo-1,2,5-tricarboxylic-3-penten acid decarboxylase | insig. | 54 | 81 |
o | Acidovorax sp. GW101-3H11 | Ac3H11_1488 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 54 | 87 |
| Paraburkholderia graminis OAS925 | ABIE53_005229 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 51 | 83 |
o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1307 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 46 | 86 |
o | Pseudomonas simiae WCS417 | PS417_17830 | | 4-hydroxyphenylacetate isomerase | insig. | 48 | 86 |
o | Pseudomonas fluorescens FW300-N2C3 | AO356_25595 | | 4-hydroxyphenylacetate isomerase | insig. | 46 | 86 |
o | Pseudomonas fluorescens SBW25 | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | insig. | 45 | 86 |
o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | strong | 45 | 86 |
o | Magnetospirillum magneticum AMB-1 | AMB_RS04125 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase | cofit | 44 | 90 |
o | Variovorax sp. OAS795 | ABID97_RS03760 | | fumarylacetoacetate hydrolase family protein | sig. | 45 | 81 |
o | Azospirillum sp. SherDot2 | MPMX19_06800 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 44 | 90 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3278 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 39 | 81 |
o | Variovorax sp. SCN45 | GFF5091 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) | insig. | 45 | 81 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03710 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 38 | 81 |
| Escherichia coli BL21 | ECD_04230 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 38 | 82 |
| Escherichia coli ECOR27 | NOLOHH_03715 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | cofit | 37 | 82 |
| Escherichia coli ECRC62 | BNILDI_07885 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 37 | 82 |
| Enterobacter sp. TBS_079 | MPMX20_00642 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 39 | 81 |
| Enterobacter asburiae PDN3 | EX28DRAFT_3547 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit/4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit | insig. | 37 | 81 |
| Klebsiella michiganensis M5al | BWI76_RS03870 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 35 | 93 |
| Klebsiella michiganensis M5al | BWI76_RS03875 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 36 | 89 |
o | Serratia liquefaciens MT49 | IAI46_02725 | | fumarylacetoacetate hydrolase family protein | insig. | 37 | 81 |
o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1829 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 39 | 88 |
| Variovorax sp. SCN45 | GFF7104 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) | insig. | 37 | 80 |
| Castellaniella sp019104865 MT123 | ABCV34_RS09310 | | fumarylacetoacetate hydrolase family protein | cofit | 36 | 96 |
| Castellaniella sp019104865 MT123 | ABCV34_RS09315 | | fumarylacetoacetate hydrolase family protein | insig. | 36 | 86 |
| Serratia liquefaciens MT49 | IAI46_02730 | | fumarylacetoacetate hydrolase family protein | insig. | 33 | 96 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS27830 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 34 | 96 |
| Pseudomonas fluorescens SBW25 | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 34 | 96 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | strong | 34 | 96 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3278 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 34 | 80 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS13530 | | fumarylacetoacetate hydrolase family protein | insig. | 35 | 98 |
| Magnetospirillum magneticum AMB-1 | AMB_RS04120 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | cofit | 31 | 96 |
| Acidovorax sp. GW101-3H11 | Ac3H11_1487 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 32 | 93 |
| Pseudomonas simiae WCS417 | PS417_17835 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 33 | 86 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1828 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 31 | 95 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS34380 | | fumarylacetoacetate hydrolase family protein | insig. | 31 | 93 |
| Azospirillum sp. SherDot2 | MPMX19_03313 | | Ureidoglycolate lyase | insig. | 33 | 86 |
| Azospirillum brasilense Sp245 | AZOBR_RS15905 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 33 | 75 |
| Azospirillum sp. SherDot2 | MPMX19_06799 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 32 | 94 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1308 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 31 | 86 |
| Variovorax sp. SCN45 | GFF5092 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 29 | 95 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03257 | | 5-carboxy-2-oxohept-3-enedioate decarboxylase HpaG2 subunit | no data | 31 | 93 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_25590 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 31 | 86 |
| Burkholderia phytofirmans PsJN | BPHYT_RS28880 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 31 | 93 |
| Variovorax sp. OAS795 | ABID97_RS03755 | | fumarylacetoacetate hydrolase family protein | sig. | 30 | 93 |
| Variovorax sp. SCN45 | GFF7103 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 35 | 73 |
| Variovorax sp. SCN45 | GFF3754 | | Fumarylacetoacetate hydrolase family protein | insig. | 30 | 87 |
| Rhizobium sp. OAE497 | ABIE40_RS19950 | | fumarylacetoacetate hydrolase family protein | insig. | 31 | 86 |
| Sinorhizobium meliloti 1021 | SM_b21112 | | L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase (from data) | strong | 32 | 86 |
| Methanococcus maripaludis JJ | MMJJ_RS04665 | | fumarylacetoacetate hydrolase family protein | insig. | 30 | 73 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS12030 | | fumarylacetoacetate hydrolase family protein | insig. | 30 | 91 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS00385 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 32 | 84 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU0875 | | fumarylacetoacetate hydrolase family protein (TIGR) | insig. | 32 | 85 |
| Paraburkholderia graminis OAS925 | ABIE53_005228 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 29 | 94 |
| Enterobacter sp. TBS_079 | MPMX20_00642 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 34 | 64 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3618 | | Putative fumarylacetoacetate (FAA) hydrolase | insig. | 32 | 83 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03710 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 32 | 83 |
| Rhodopseudomonas palustris CGA009 | TX73_022935 | | fumarylacetoacetate hydrolase family protein | insig. | 32 | 74 |
| Escherichia coli ECOR27 | NOLOHH_03715 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | cofit | 32 | 83 |
| Escherichia coli ECRC62 | BNILDI_07885 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 32 | 83 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_2636 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 32 | 97 |
| Methanococcus maripaludis S2 | MMP_RS00825 | | fumarylacetoacetate hydrolase family protein | insig. | 30 | 73 |
| Agrobacterium fabrum C58 | Atu0014 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | strong | 30 | 84 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.5166.1 | | hypothetical protein | insig. | 32 | 76 |
| Enterobacter asburiae PDN3 | EX28DRAFT_3547 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit/4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit | insig. | 35 | 63 |
| Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS07700 | | fumarylacetoacetate hydrolase family protein | insig. | 32 | 81 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS19960 | | fumarylacetoacetate hydrolase family protein | insig. | 30 | 74 |
| Burkholderia phytofirmans PsJN | BPHYT_RS34210 | | 2,4-diketo-3-deoxy-L-rhamnonate hydrolase (EC 3.7.1.-) (from data) | strong | 33 | 74 |
| Variovorax sp. OAS795 | ABID97_RS26355 | | fumarylacetoacetate hydrolase family protein | insig. | 28 | 87 |
| Escherichia coli BL21 | ECD_04230 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 31 | 83 |
| Azospirillum sp. SherDot2 | MPMX19_06074 | | Ureidoglycolate lyase | insig. | 30 | 96 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03528 | | ureidoglycolate lyase | sig. | 32 | 74 |
| Ralstonia solanacearum PSI07 | RPSI07_RS21875 | | FAA hydrolase family protein | insig. | 31 | 87 |
| Rhizobium sp. OAE497 | ABIE40_RS19310 | | fumarylacetoacetate hydrolase family protein | strong | 31 | 84 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS17220 | | ureidoglycolate lyase | insig. | 32 | 71 |
| Variovorax sp. SCN45 | GFF4615 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase | insig. | 32 | 73 |
| Paraburkholderia graminis OAS925 | ABIE53_004732 | | ureidoglycolate lyase | strong | 32 | 74 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_24305 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 32 | 74 |
| Acidovorax sp. GW101-3H11 | Ac3H11_4136 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. | insig. | 35 | 65 |
| Azospirillum brasilense Sp245 | AZOBR_RS26375 | | hypothetical protein | insig. | 32 | 73 |
| Phaeobacter inhibens DSM 17395 | PGA1_c04530 | | ureidoglycolate lyase | insig. | 31 | 74 |
| Ralstonia solanacearum GMI1000 | RS_RS09200 | | FAA hydrolase family protein | sig. | 28 | 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4225 | | Fumarylacetoacetate hydrolase family protein | insig. | 31 | 73 |
| Variovorax sp. OAS795 | ABID97_RS05835 | | fumarylacetoacetate hydrolase family protein | strong | 31 | 73 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01325 | | fumarylacetoacetate hydrolase family protein | insig. | 30 | 77 |
| Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS08350 | | ureidoglycolate lyase | insig. | 31 | 78 |
| Variovorax sp. OAS795 | ABID97_RS25485 | | fumarylacetoacetate hydrolase family protein | insig. | 31 | 85 |
| Mycobacterium tuberculosis H37Rv | Rv2993c | | Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) | insig. | 32 | 72 |
| Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_05461 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 33 | 72 |
| Klebsiella michiganensis M5al | BWI76_RS05690 | | fumarylacetoacetate (FAA) hydrolase | insig. | 33 | 73 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_00660 | | 5-carboxymethyl-2-hydroxymuconate isomerase | insig. | 31 | 73 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS06355 | | 2,4-diketo-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) (from data) | strong | 31 | 71 |
| Dinoroseobacter shibae DFL-12 | Dshi_2542 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase (RefSeq) | insig. | 28 | 73 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS20835 | | ureidoglycolate lyase | insig. | 34 | 71 |