Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4501 | | 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) [enterobactin] siderophore | insig. | 100 | 100 |
o | Escherichia fergusonii Becca | EFB2_03498 | | Enterobactin synthase component E | insig. | 87 | 100 |
o | Escherichia coli ECOR27 | NOLOHH_23945 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | cofit | 86 | 100 |
o | Escherichia coli ECRC62 | BNILDI_21955 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | insig. | 86 | 100 |
o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03112 | | Enterobactin synthase component E | insig. | 86 | 100 |
o | Escherichia coli BW25113 | b0594 | entE | 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex (NCBI) | insig. | 86 | 100 |
o | Escherichia coli BL21 | ECD_00561 | | 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex | insig. | 86 | 100 |
o | Escherichia coli Nissle 1917 | ECOLIN_RS03260 | | (2,3-dihydroxybenzoyl)adenylate synthase EntE | insig. | 86 | 100 |
o | Escherichia coli ECRC101 | OKFHMN_07570 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | insig. | 86 | 100 |
o | Escherichia coli ECRC101 | MCAODC_26785 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | insig. | 86 | 100 |
o | Escherichia coli ECRC102 | NIAGMN_05625 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | insig. | 86 | 100 |
o | Escherichia coli ECRC98 | JDDGAC_11215 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | no data | 86 | 100 |
o | Escherichia coli ECRC99 | KEDOAH_20400 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | no data | 86 | 100 |
o | Escherichia coli ECOR38 | HEPCGN_00710 | entE | (2,3-dihydroxybenzoyl)adenylate synthase EntE | cofit | 86 | 100 |
o | Klebsiella michiganensis M5al | BWI76_RS07750 | | 2,3-dihydroxybenzoate-AMP ligase | insig. | 80 | 99 |
o | Enterobacter asburiae PDN3 | EX28DRAFT_2373 | | 2,3-dihydroxybenzoate-AMP ligase | insig. | 80 | 100 |
o | Enterobacter sp. TBS_079 | MPMX20_01248 | | Enterobactin synthase component E | insig. | 79 | 100 |
o | Serratia liquefaciens MT49 | IAI46_18320 | | (2,3-dihydroxybenzoyl)adenylate synthase | insig. | 70 | 99 |
o | Dickeya dianthicola ME23 | DZA65_RS15595 | | (2,3-dihydroxybenzoyl)adenylate synthase | insig. | 66 | 99 |
o | Dickeya dadantii 3937 | DDA3937_RS14710 | | (2,3-dihydroxybenzoyl)adenylate synthase | insig. | 67 | 99 |
o | Dickeya dianthicola 67-19 | HGI48_RS14650 | | (2,3-dihydroxybenzoyl)adenylate synthase | insig. | 67 | 99 |
o | Pectobacterium carotovorum WPP14 | HER17_RS19015 | | (2,3-dihydroxybenzoyl)adenylate synthase | insig. | 61 | 99 |
o | Azospirillum brasilense Sp245 | AZOBR_RS29555 | | enterobactin synthase subunit E | insig. | 55 | 100 |
o | Pseudomonas fluorescens FW300-N2E3 | AO353_23995 | | 2,3-dihydroxybenzoate-AMP ligase | sig. | 55 | 100 |
o | Vibrio cholerae E7946 ATCC 55056 | CSW01_04005 | | 2,3-dihydroxybenzoate-AMP ligase | insig. | 46 | 99 |
o | Pseudomonas simiae WCS417 | PS417_13215 | | Triostin synthetase I | insig. | 47 | 98 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS18985 | | salicylate synthase | insig. | 43 | 94 |
| Ralstonia solanacearum UW163 | UW163_RS20145 | | salicylate synthase | insig. | 43 | 94 |
| Klebsiella michiganensis M5al | BWI76_RS14550 | | 2,3-dihydroxybenzoate-AMP ligase | insig. | 43 | 91 |
| Escherichia fergusonii Becca | EFB2_01937 | | 2,3-dihydroxybenzoate-AMP ligase | insig. | 42 | 91 |
| Escherichia coli ECOR38 | HEPCGN_03550 | ybtE | yersiniabactin biosynthesis salycil-AMP ligase YbtE | cofit | 42 | 91 |
| Escherichia coli Nissle 1917 | ECOLIN_RS11415 | | yersiniabactin biosynthesis salycil-AMP ligase YbtE | no data | 42 | 91 |
o | Mycobacterium tuberculosis H37Rv | Rv2384 | | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | insig. | 41 | 98 |
o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF439 | | 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) | insig. | 39 | 99 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3540 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 34 | 97 |
o | Cupriavidus basilensis FW507-4G11 | RR42_RS24145 | | hypothetical protein | insig. | 32 | 98 |
| Escherichia coli BW25113 | b1701 | fadK | short chain acyl-CoA synthetase, anaerobic (RefSeq) | insig. | 33 | 97 |
| Escherichia coli ECOR38 | HEPCGN_05535 | fadK | medium-chain fatty-acid--CoA ligase | cofit | 33 | 97 |
| Escherichia coli BL21 | ECD_01670 | | short chain acyl-CoA synthetase, anaerobic | no data | 32 | 97 |
| Escherichia coli ECRC101 | OKFHMN_27150 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 32 | 97 |
| Escherichia coli ECRC102 | NIAGMN_00915 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 32 | 97 |
| Escherichia coli ECRC98 | JDDGAC_01725 | fadK | medium-chain fatty-acid--CoA ligase | no data | 32 | 97 |
| Escherichia coli ECRC99 | KEDOAH_00960 | fadK | medium-chain fatty-acid--CoA ligase | no data | 32 | 97 |
| Escherichia fergusonii Becca | EFB2_02290 | | Medium-chain fatty-acid--CoA ligase | insig. | 33 | 97 |
| Escherichia coli ECOR27 | NOLOHH_17670 | fadK | medium-chain fatty-acid--CoA ligase | no data | 33 | 97 |
| Escherichia coli Nissle 1917 | ECOLIN_RS09505 | | medium-chain fatty-acid--CoA ligase | no data | 33 | 97 |
| Acinetobacter radioresistens SK82 | MPMX26_01930 | | Medium-chain fatty-acid--CoA ligase | no data | 29 | 96 |
| Variovorax sp. SCN45 | GFF4304 | | Cyclohexanecarboxylate--CoA ligase | insig. | 31 | 95 |
| Rhodopseudomonas palustris CGA009 | TX73_003375 | | cyclohexanecarboxylate-CoA ligase | insig. | 30 | 95 |
| Escherichia coli ECRC62 | BNILDI_16460 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 32 | 93 |
| Burkholderia phytofirmans PsJN | BPHYT_RS31895 | | hypothetical protein | insig. | 30 | 97 |
| Marinobacter adhaerens HP15 | HP15_4144 | | short chain acyl-CoA synthetase | cofit | 28 | 96 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS23705 | | cyclohexanecarboxylate--CoA ligase | insig. | 30 | 90 |
| Castellaniella sp019104865 MT123 | ABCV34_RS03750 | | cyclohexanecarboxylate-CoA ligase | insig. | 28 | 97 |
| Escherichia coli ECRC101 | MCAODC_18260 | fadK | medium-chain fatty-acid--CoA ligase | insig. | 33 | 90 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_0256 | | AMP-dependent synthetase and ligase (RefSeq) | sig. | 29 | 94 |
| Sinorhizobium meliloti 1021 | SMa0150 | | malonyl-CoA synthase | insig. | 28 | 94 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF907 | | 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) | insig. | 27 | 97 |
| Rhodopseudomonas palustris CGA009 | TX73_022915 | | class I adenylate-forming enzyme family protein | insig. | 30 | 94 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS19225 | | AMP-dependent synthetase | insig. | 29 | 98 |
| Ralstonia solanacearum UW163 | UW163_RS19905 | | AMP-dependent synthetase | insig. | 29 | 98 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU1453 | fadD | long-chain-fatty-acid--CoA ligase (TIGR) | insig. | 29 | 96 |
| Serratia liquefaciens MT49 | IAI46_12690 | | long-chain fatty acid--CoA ligase | insig. | 30 | 91 |
| Methanococcus maripaludis S2 | MMP_RS02990 | | AMP-binding protein | insig. | 27 | 92 |
| Azospirillum sp. SherDot2 | MPMX19_02790 | | Long-chain-fatty-acid--CoA ligase | insig. | 30 | 92 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS36410 | | acyl-CoA synthetase | insig. | 30 | 90 |
| Pseudomonas putida KT2440 | PP_3458 | | Butyrate--CoA ligase | sig. | 29 | 92 |
| Rhodopseudomonas palustris CGA009 | TX73_003840 | | long-chain fatty acid--CoA ligase | insig. | 29 | 94 |
| Methanococcus maripaludis JJ | MMJJ_RS02080 | | AMP-binding protein | insig. | 26 | 92 |
| Mycobacterium tuberculosis H37Rv | Rv0119 | | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | no data | 27 | 93 |
| Mycobacterium tuberculosis H37Rv | Rv1058 | | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | sig. | 29 | 96 |
| Magnetospirillum magneticum AMB-1 | AMB_RS18140 | | malonyl-CoA synthase | insig. | 28 | 91 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS19075 | | acyl-CoA synthetase | insig. | 26 | 94 |
| Shewanella amazonensis SB2B | Sama_1904 | | AMP-binding domain protein (RefSeq) | insig. | 27 | 94 |
| Ralstonia solanacearum PSI07 | RPSI07_RS04070 | | AMP-dependent synthetase | insig. | 27 | 98 |
| Shewanella sp. ANA-3 | Shewana3_2475 | | AMP-binding domain protein (RefSeq) | insig. | 26 | 94 |
| Alteromonas macleodii MIT1002 | MIT1002_03360 | | Long-chain-fatty-acid--CoA ligase | insig. | 26 | 94 |
| Variovorax sp. SCN45 | GFF5683 | | Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 27 | 93 |
| Pseudomonas fluorescens SBW25 | PFLU_RS18960 | | AMP-binding protein | cofit | 27 | 93 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS18960 | | AMP-binding protein | insig. | 27 | 93 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_0835 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 27 | 98 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_2521 | | Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD3 | insig. | 27 | 92 |
| Marinobacter adhaerens HP15 | HP15_3926 | | acyl-CoA synthetase | insig. | 26 | 98 |
| Mycobacterium tuberculosis H37Rv | Rv2505c | | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | insig. | 29 | 90 |
| Pseudomonas simiae WCS417 | PS417_17010 | | AMP-binding protein | insig. | 28 | 92 |
| Shewanella oneidensis MR-1 | SO1971 | | AMP-binding family protein (NCBI ptt file) | insig. | 26 | 94 |
| Azospirillum brasilense Sp245 | AZOBR_RS21705 | | 2-aminobenzoate-CoA ligase | strong | 29 | 94 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2190 | | Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) | insig. | 28 | 93 |
| Agrobacterium fabrum C58 | Atu4822 | | acyl-CoA synthetase | insig. | 26 | 95 |
| Rhodopseudomonas palustris CGA009 | TX73_005160 | | AMP-binding protein | insig. | 28 | 94 |
| Acidovorax sp. GW101-3H11 | Ac3H11_4478 | | Acetyl-coenzyme A synthetase (EC 6.2.1.1) | insig. | 28 | 94 |
| Acinetobacter radioresistens SK82 | MPMX26_00634 | | 3-[(3aS,4S,7aS)-7a-methyl-1, 5-dioxo-octahydro-1H-inden-4-yl]propanoyl:CoA ligase | insig. | 26 | 93 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS29430 | | acyl-CoA synthetase | insig. | 31 | 83 |
| Shewanella loihica PV-4 | Shew_2593 | | acyl-CoA synthetase (RefSeq) | insig. | 26 | 94 |
| Caulobacter crescentus NA1000 | CCNA_03292 | | long-chain-fatty-acid--CoA ligase | cofit | 29 | 93 |
| Caulobacter crescentus NA1000 Δfur | CCNA_03292 | | long-chain-fatty-acid--CoA ligase | cofit | 29 | 93 |
| Pseudomonas putida KT2440 | PP_2795 | | AMP-binding domain protein | sig. | 28 | 91 |
| Variovorax sp. OAS795 | ABID97_RS28255 | | long-chain-fatty-acid--CoA ligase | insig. | 28 | 99 |
| Sphingomonas koreensis DSMZ 15582 | Ga0059261_1004 | | Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II | insig. | 28 | 100 |
| Paraburkholderia sabiae LMG 24235 | QEN71_RS27455 | | long-chain fatty acid--CoA ligase | cofit | 27 | 90 |