| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1870 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase (EC 2.2.1.9) | insig. | 100 | 100 |
| o | Escherichia coli BL21 | ECD_02191 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; SEPHCHC synthase | insig. | 91 | 100 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01446 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | insig. | 91 | 100 |
| o | Escherichia coli BW25113 | b2264 | menD | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase (NCBI) | sig. | 91 | 100 |
| o | Escherichia coli ECRC100 | OKFHMN_22935 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 91 | 100 |
| o | Escherichia coli ECRC101 | MCAODC_13975 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 91 | 100 |
| o | Escherichia coli ECRC102 | NIAGMN_20705 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 91 | 100 |
| o | Escherichia coli ECRC62 | BNILDI_13475 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | cofit | 91 | 100 |
| o | Escherichia coli ECRC98 | JDDGAC_26900 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | sig. | 91 | 100 |
| o | Escherichia coli ECRC99 | KEDOAH_05260 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | no data | 91 | 100 |
| o | Escherichia coli ECOR38 | HEPCGN_22150 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 90 | 100 |
| o | Escherichia coli ECOR27 | NOLOHH_14560 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene- 1-carboxylic-acid synthase | insig. | 91 | 100 |
| o | Escherichia fergusonii Becca | EFB2_01591 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | insig. | 90 | 100 |
| o | Escherichia coli Nissle 1917 | ECOLIN_RS13185 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 90 | 100 |
| o | Enterobacter sp. TBS_079 | MPMX20_03200 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | insig. | 85 | 100 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_0340 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | insig. | 84 | 100 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_26990 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | insig. | 84 | 100 |
| o | Klebsiella michiganensis M5al | BWI76_RS20075 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | sig. | 83 | 100 |
| o | Serratia liquefaciens MT49 | IAI46_17560 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 72 | 100 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS15555 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 68 | 100 |
| o | Dickeya dadantii 3937 | DDA3937_RS05915 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 67 | 99 |
| o | Dickeya dianthicola 67-19 | HGI48_RS05960 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 67 | 100 |
| o | Dickeya dianthicola ME23 | DZA65_RS06295 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 66 | 100 |
| o | Rahnella sp. WP5 | EX31_RS19355 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 65 | 100 |
| o | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_18170 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | insig. | 61 | 99 |
| o | Erwinia tracheiphila SCR3 | LU632_RS08105 | menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 61 | 99 |
| o | Vibrio cholerae E7946 ATCC 55056 | CSW01_09860 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase | cofit | 44 | 99 |
| o | Shewanella amazonensis SB2B | Sama_3460 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase (RefSeq) | strong | 43 | 99 |
| o | Shewanella sp. ANA-3 | Shewana3_3965 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase (RefSeq) | strong | 41 | 99 |
| o | Shewanella loihica PV-4 | Shew_3599 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase (RefSeq) | strong | 41 | 98 |
| o | Shewanella oneidensis MR-1 | SO4573 | menD | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase (NCBI ptt file) | strong | 40 | 99 |
| o | Synechococcus elongatus PCC 7942 | Synpcc7942_1435 | menD | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase | no data | 32 | 93 |
| o | Synechocystis sp000284455 PCC 6803 | SGL_RS14335 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | strong | 31 | 99 |
| o | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_08835 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | no data | 29 | 96 |
| o | Cellulophaga baltica 18 | M666_RS13690 | | thiamine pyrophosphate-binding protein | no data | 28 | 91 |
| o | Bacteroides thetaiotaomicron VPI-5482 | BT4701 | | 2-oxoglutarate decarboxylase and 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (NCBI ptt file) | no data | 28 | 97 |
| o | Bacteroides stercoris CC31F | HMPREF1181_RS15695 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | insig. | 31 | 84 |
| o | Bacteroides ovatus ATCC 8483 | BACOVA_05551 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | strong | 28 | 97 |
| o | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2344 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | no data | 26 | 94 |
| o | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS01045 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 28 | 91 |
| o | Phocaeicola dorei CL03T12C01 | ABI39_RS12140 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | strong | 28 | 97 |
| o | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS16250 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | strong | 28 | 97 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4413 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase | strong | 25 | 90 |
| o | Mycobacterium tuberculosis H37Rv | Rv0555 | | Probable bifunctional menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) + 2-oxoglutarate decarboxylase (alpha-ketoglutarate decarboxylase) (KDC) | no data | 40 | 31 |
| o | Dechlorosoma suillum PS | Dsui_2922 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 42 | 27 |
| o | Dechlorosoma suillum PS | Dsui_2922 | | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase | cofit | 37 | 34 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS11070 | | thiamine pyrophosphate-binding protein | cofit | 35 | 17 |
| | Rhodopseudomonas palustris CGA009 | TX73_010465 | | acetolactate synthase 3 large subunit | no data | 29 | 27 |
| o | Mycobacterium tuberculosis H37Rv | Rv0555 | | Probable bifunctional menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (SHCHC synthase) + 2-oxoglutarate decarboxylase (alpha-ketoglutarate decarboxylase) (KDC) | no data | 35 | 20 |
| | Shewanella loihica PV-4 | Shew_1408 | | thiamine pyrophosphate binding domain-containing protein (RefSeq) | no data | 24 | 42 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS11995 | | thiamine pyrophosphate-binding protein | insig. | 25 | 29 |
| | Sphingobium sp. HT1-2 | GFF2054 | | Acetolactate synthase large subunit (EC 2.2.1.6) | strong | 30 | 21 |
| | Dechlorosoma suillum PS | Dsui_1925 | | acetolactate synthase, large subunit, biosynthetic type | sig. | 30 | 21 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF298 | | Acetolactate synthase large subunit (EC 2.2.1.6) | insig. | 30 | 21 |
| | Caulobacter crescentus NA1000 | CCNA_02185 | | acetolactate synthase large subunit | strong | 24 | 46 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02185 | | acetolactate synthase large subunit | insig. | 24 | 46 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3954 | | acetolactate synthase, large subunit (EC 2.2.1.6) | cofit | 30 | 21 |
| | Enterobacter sp. TBS_079 | MPMX20_00031 | | Acetolactate synthase isozyme 1 large subunit | sig. | 30 | 21 |
| | Rhizobium sp. OAE497 | ABIE40_RS11495 | | acetolactate synthase 3 large subunit | strong | 27 | 27 |
| | Azospirillum sp. SherDot2 | MPMX19_01776 | | Acetolactate synthase isozyme 3 large subunit | no data | 23 | 62 |
| | Serratia liquefaciens MT49 | IAI46_03295 | | acetolactate synthase large subunit | insig. | 29 | 21 |
| | Agrobacterium fabrum C58 | Atu2036 | | acetolactate synthase III, large subunit | strong | 26 | 27 |
| | Sinorhizobium meliloti 1021 | SMc01431 | | acetolactate synthase 3 catalytic subunit | strong | 25 | 29 |
| | Dickeya dianthicola ME23 | DZA65_RS19270 | | acetolactate synthase large subunit | cofit | 28 | 21 |
| | Escherichia coli ECRC100 | OKFHMN_15150 | | Acetolactate synthase | cofit | 27 | 22 |
| | Escherichia coli ECRC101 | MCAODC_05660 | | Acetolactate synthase | sig. | 27 | 22 |
| | Escherichia coli ECRC102 | NIAGMN_12910 | | Acetolactate synthase | cofit | 27 | 22 |
| | Escherichia coli ECRC98 | JDDGAC_18775 | | Acetolactate synthase | insig. | 27 | 22 |
| | Escherichia coli ECRC99 | KEDOAH_13000 | | Acetolactate synthase | no data | 27 | 22 |
| | Klebsiella michiganensis M5al | BWI76_RS27815 | | acetolactate synthase catalytic subunit | strong | 27 | 21 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS11995 | | thiamine pyrophosphate-binding protein | insig. | 31 | 20 |
| | Dickeya dianthicola 67-19 | HGI48_RS18120 | | acetolactate synthase large subunit | insig. | 28 | 21 |
| | Pectobacterium carotovorum WPP14 | HER17_RS03015 | | acetolactate synthase large subunit | cofit | 28 | 21 |
| | Escherichia coli ECOR38 | HEPCGN_13885 | | Acetolactate synthase | insig. | 28 | 21 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_08515 | | acetolactate synthase large subunit | insig. | 27 | 21 |
| | Escherichia coli BL21 | ECD_03555 | | acetolactate synthase 2 large subunit | strong | 28 | 21 |
| | Escherichia fergusonii Becca | EFB2_00027 | | Acetolactate synthase isozyme 1 large subunit | insig. | 28 | 21 |
| | Escherichia coli ECOR27 | NOLOHH_07325 | | Acetolactate synthase | insig. | 28 | 21 |
| | Escherichia coli ECRC62 | BNILDI_04200 | | Acetolactate synthase | cofit | 28 | 21 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00029 | | Acetolactate synthase isozyme 1 large subunit | insig. | 28 | 21 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS21180 | | acetolactate synthase large subunit | insig. | 28 | 21 |
| | Escherichia coli BW25113 | b3671 | ilvB | acetolactate synthase large subunit (NCBI) | strong | 28 | 21 |
| | Dickeya dadantii 3937 | DDA3937_RS18170 | | acetolactate synthase large subunit | cofit | 28 | 21 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0360 | ilvB-1 | acetolactate synthase, large subunit, biosynthetic type (TIGR) | strong | 27 | 22 |
| | Pseudomonas sp. BP01 | JOY50_RS08100 | | 5-guanidino-2-oxopentanoate decarboxylase | insig. | 24 | 94 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1883 | | acetolactate synthase catalytic subunit (RefSeq) | strong | 28 | 21 |
| | Pseudomonas putida KT2440 | PP_3723 | | putative 2-ketoarginine decarboxylase AruI | sig. | 28 | 24 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS13010 | | acetolactate synthase 3 large subunit | strong | 29 | 25 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0603 | | Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] | insig. | 25 | 58 |
| | Shewanella oneidensis MR-1 | SO3262 | ilvB | acetolactate synthase isozyme I, large subunit (NCBI ptt file) | strong | 30 | 21 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c20210 | | acetolactate synthase isozyme 3 large subunit | strong | 28 | 28 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS21705 | | sulfoacetaldehyde acetyltransferase | strong | 26 | 50 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS33685 | | sulfoacetaldehyde acetyltransferase | no data | 25 | 42 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS33775 | | sulfoacetaldehyde acetyltransferase | no data | 25 | 42 |
| | Bosea sp. OAE506 | ABIE41_RS12890 | | acetolactate synthase 3 large subunit | no data | 29 | 24 |
| | Serratia liquefaciens MT49 | IAI46_03375 | | acetolactate synthase 3 large subunit | insig. | 29 | 25 |
| | Shewanella loihica PV-4 | Shew_1776 | | acetolactate synthase 3 catalytic subunit (RefSeq) | strong | 28 | 24 |
| | Pantoea sp. MT58 | IAI47_15990 | | acetolactate synthase 3 large subunit | cofit | 29 | 25 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_05990 | ilvI | acetolactate synthase 3 large subunit | cofit | 27 | 25 |
| | Erwinia tracheiphila SCR3 | LU632_RS02885 | ilvI | acetolactate synthase 3 large subunit | insig. | 27 | 25 |