Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Acidovorax sp. GW101-3H11 | Ac3H11_2287 | | HD-GYP domain | insig. | 100 | 100 |
| Shewanella amazonensis SB2B | Sama_1539 | | putative metal dependent phosphohydrolase (RefSeq) | strong | 33 | 90 |
o | Vibrio cholerae E7946 ATCC 55056 | CSW01_12655 | | HD-GYP domain-containing protein | insig. | 37 | 90 |
| Acidovorax sp. GW101-3H11 | Ac3H11_979 | | HD-GYP domain | insig. | 34 | 90 |
| Dechlorosoma suillum PS | Dsui_1868 | | HD-GYP domain-containing protein | insig. | 35 | 90 |
| Shewanella loihica PV-4 | Shew_2351 | | metal dependent phosphohydrolase (RefSeq) | no data | 33 | 90 |
| Shewanella sp. ANA-3 | Shewana3_1721 | | metal dependent phosphohydrolase (RefSeq) | sig. | 33 | 90 |
| Shewanella oneidensis MR-1 | SO1942 | | HDIG domain protein (NCBI ptt file) | insig. | 34 | 90 |
| Pseudomonas sp. S08-1 | OH686_09770 | | Metal-dependent phosphohydrolase | insig. | 33 | 90 |
| Shewanella oneidensis MR-1 | SO2862 | | HDIG domain protein (NCBI ptt file) | sig. | 31 | 89 |
| Shewanella sp. ANA-3 | Shewana3_1571 | | metal dependent phosphohydrolase (RefSeq) | insig. | 31 | 89 |
| Shewanella amazonensis SB2B | Sama_1519 | | putative metal dependent phosphohydrolase (RefSeq) | sig. | 27 | 90 |
| Shewanella loihica PV-4 | Shew_2375 | | metal dependent phosphohydrolase (RefSeq) | no data | 26 | 91 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS08200 | | HD-GYP domain-containing protein | sig. | 30 | 79 |
| Cupriavidus basilensis FW507-4G11 | RR42_RS11195 | | phosphohydrolase | insig. | 28 | 79 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS12275 | | HD-GYP domain-containing protein | insig. | 29 | 79 |
| Ralstonia solanacearum UW163 | UW163_RS01330 | | HD-GYP domain-containing protein | insig. | 29 | 79 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU0491 | | HDIG domain protein (TIGR) | insig. | 25 | 87 |
| Ralstonia solanacearum PSI07 | RPSI07_RS21040 | | HD-GYP domain-containing protein | insig. | 28 | 79 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_0128 | | uncharacterized domain HDIG | insig. | 25 | 64 |
| Ralstonia solanacearum GMI1000 | RS_RS02965 | | HD-GYP domain-containing protein | insig. | 28 | 79 |
| Alteromonas macleodii MIT1002 | MIT1002_04107 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 30 | 65 |
| Pantoea sp. MT58 | IAI47_01225 | | HD-GYP domain-containing protein | insig. | 29 | 79 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_1796 | | uncharacterized domain HDIG | cofit | 28 | 53 |
| Dechlorosoma suillum PS | Dsui_0757 | | HD-GYP domain-containing protein | insig. | 25 | 87 |
| Dechlorosoma suillum PS | Dsui_0643 | | HD-GYP domain-containing protein | insig. | 26 | 79 |
| Dechlorosoma suillum PS | Dsui_2393 | | uncharacterized domain HDIG-containing protein | cofit | 28 | 75 |
| Marinobacter adhaerens HP15 | HP15_3532 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 30 | 48 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_0130 | | uncharacterized domain HDIG | insig. | 25 | 58 |
| Kangiella aquimarina DSM 16071 | B158DRAFT_0129 | | uncharacterized domain HDIG | insig. | 25 | 60 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_1719 | | metal dependent phosphohydrolase (RefSeq) | sig. | 25 | 86 |
| Marinobacter adhaerens HP15 | HP15_4049 | | HD-GYP domain protein | insig. | 32 | 47 |
| Marinobacter adhaerens HP15 | HP15_4053 | | metal-dependent phosphohydrolase, HD subdomain protein | insig. | 27 | 59 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS13405 | | phosphodiesterase | insig. | 25 | 84 |
| Marinobacter adhaerens HP15 | HP15_p187g147 | | HD-GYP domain protein | insig. | 25 | 83 |
| Pseudomonas stutzeri RCH2 | Psest_4130 | | uncharacterized domain HDIG | insig. | 26 | 75 |
| Acidovorax sp. GW101-3H11 | Ac3H11_780 | | HDIG domain protein | insig. | 26 | 76 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS04735 | | phosphodiesterase | insig. | 25 | 82 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS04880 | | phosphodiesterase | insig. | 23 | 83 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS19965 | | phosphodiesterase | insig. | 27 | 80 |
| Pseudomonas stutzeri RCH2 | Psest_2721 | | HD-GYP domain | insig. | 28 | 55 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.460.1 | | HDIG domain protein | insig. | 26 | 79 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_29890 | | phosphodiesterase | insig. | 27 | 79 |
| Shewanella sp. ANA-3 | Shewana3_4069 | | metal dependent phosphohydrolase (RefSeq) | strong | 28 | 49 |
| Acidovorax sp. GW101-3H11 | Ac3H11_895 | | HDIG domain protein | insig. | 32 | 42 |
| Marinobacter adhaerens HP15 | HP15_1459 | | metal dependent phosphohydrolase | insig. | 24 | 52 |
| Ralstonia solanacearum PSI07 | RPSI07_RS12300 | | HD-GYP domain-containing protein | insig. | 26 | 75 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS23735 | | phosphodiesterase | insig. | 25 | 78 |
| Shewanella amazonensis SB2B | Sama_0136 | | putative metal dependent phosphohydrolase (RefSeq) | cofit | 29 | 49 |
| Shewanella oneidensis MR-1 | SO4711 | | HD domain protein (NCBI ptt file) | strong | 28 | 49 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS00610 | | HD-GYP domain-containing protein | insig. | 31 | 43 |
| Shewanella loihica PV-4 | Shew_3670 | | metal dependent phosphohydrolase (RefSeq) | insig. | 29 | 49 |
| Pseudomonas sp. S08-1 | OH686_14780 | | HD-GYP domain | insig. | 25 | 79 |
| Ralstonia solanacearum GMI1000 | RS_RS12610 | | HD-GYP domain-containing protein | insig. | 26 | 75 |
| Ralstonia solanacearum IBSBF1503 | RALBFv3_RS04990 | | HD-GYP domain-containing protein | insig. | 30 | 48 |
| Ralstonia solanacearum UW163 | UW163_RS08635 | | HD-GYP domain-containing protein | insig. | 30 | 48 |
| Pseudomonas syringae pv. syringae B728a | Psyr_0994 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 27 | 49 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0994 | | Metal-dependent phosphohydrolase, HD subdomain protein | insig. | 27 | 49 |
| Pseudomonas sp. RS175 | PFR28_01424 | | Cyclic di-GMP phosphodiesterase | insig. | 28 | 49 |
| Marinobacter adhaerens HP15 | HP15_3910 | | metal dependent phosphohydrolase | insig. | 28 | 49 |
| Marinobacter adhaerens HP15 | HP15_3421 | | metal-dependent phosphohydrolase, HD subdomain protein | insig. | 26 | 57 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1785 | | HDIG domain protein | insig. | 27 | 79 |
| Pseudomonas fluorescens SBW25 | PFLU_RS26120 | | HD domain-containing protein | insig. | 26 | 53 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS26120 | | HD domain-containing protein | insig. | 26 | 53 |
| Castellaniella sp019104865 MT123 | ABCV34_RS14075 | | HD-GYP domain-containing protein | cofit | 29 | 49 |
| Alteromonas macleodii MIT1002 | MIT1002_00945 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 25 | 65 |
| Shewanella loihica PV-4 | Shew_2259 | | metal dependent phosphohydrolase (RefSeq) | sig. | 27 | 51 |
| Agrobacterium fabrum C58 | Atu2291 | | hypothetical protein | insig. | 26 | 47 |
| Rhizobium sp. OAE497 | ABIE40_RS28400 | | HD-GYP domain-containing protein | insig. | 30 | 47 |
| Shewanella sp. ANA-3 | Shewana3_2820 | | metal dependent phosphohydrolase (RefSeq) | insig. | 29 | 43 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS15775 | | phosphohydrolase | insig. | 36 | 29 |
| Rhodanobacter denitrificans MT42 | LRK55_RS15530 | | HD domain-containing phosphohydrolase | cofit | 33 | 41 |
| Magnetospirillum magneticum AMB-1 | AMB_RS04305 | | HD domain-containing protein | cofit | 27 | 47 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU0129 | | sensory box/HDIG domain protein (TIGR) | insig. | 28 | 36 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU1181 | | response regulator (TIGR) | cofit | 27 | 53 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU0667 | | HD domain protein (TIGR) | insig. | 33 | 35 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_3074 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | cofit | 26 | 43 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU2515 | | HD domain protein (TIGR) | strong | 30 | 35 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4953 | | hypothetical protein | insig. | 28 | 44 |
| Lysobacter sp. OAE881 | ABIE51_RS11560 | | two-component system response regulator | strong | 26 | 50 |
| Magnetospirillum magneticum AMB-1 | AMB_RS23530 | | HD domain-containing protein | cofit | 31 | 34 |
| Acidovorax sp. GW101-3H11 | Ac3H11_3168 | | Response regulator | insig. | 32 | 36 |
| Pseudomonas sp. S08-1 | OH686_00410 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 30 | 35 |
| Dechlorosoma suillum PS | Dsui_0938 | | HD-GYP domain-containing protein | insig. | 28 | 43 |
| Dechlorosoma suillum PS | Dsui_3001 | | putative domain HDIG-containing protein | insig. | 28 | 34 |
| Rhizobium sp. OAE497 | ABIE40_RS13525 | | HD-GYP domain-containing protein | insig. | 21 | 72 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01775 | | HD-GYP domain-containing protein | insig. | 30 | 33 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_0966 | | metal dependent phosphohydrolase (RefSeq) | strong | 31 | 33 |
| Rhodanobacter denitrificans MT42 | LRK55_RS17470 | | HD domain-containing phosphohydrolase | cofit | 31 | 34 |
| Rhodanobacter denitrificans FW104-10B01 | LRK54_RS17245 | | HD domain-containing protein | insig. | 31 | 34 |
| Rhodanobacter sp. FW510-T8 | OKGIIK_07645 | | Phosphohydrolase | insig. | 29 | 41 |
| Dechlorosoma suillum PS | Dsui_2629 | | HD-GYP domain-containing protein | cofit | 28 | 43 |
| Bosea sp. OAE506 | ABIE41_RS20055 | | HD domain-containing phosphohydrolase | insig. | 27 | 33 |
| Dechlorosoma suillum PS | Dsui_1886 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 28 | 34 |
| Herbaspirillum seropedicae SmR1 | HSERO_RS23505 | | transcriptional regulator | strong | 29 | 33 |
| Magnetospirillum magneticum AMB-1 | AMB_RS06150 | | HD-GYP domain-containing protein | cofit | 27 | 45 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.2900.1 | | response regulator | strong | 27 | 44 |
| Azospirillum sp. SherDot2 | MPMX19_05263 | | hypothetical protein | insig. | 27 | 34 |
| Rhodopseudomonas palustris CGA009 | TX73_000745 | | response regulator | insig. | 31 | 34 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU1020 | | HD domain/sensory box protein (TIGR) | insig. | 27 | 34 |