Conservation of cofitness between Rv0374c and Rv3313c in Mycobacterium tuberculosis H37Rv

54 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Mycobacterium tuberculosis H37Rv 1.0 Rv0374c Probable carbon monoxyde dehydrogenase (small chain) 1.0 Rv3313c Probable adenosine deaminase Add (adenosine aminohydrolase) 0.18 16
Cupriavidus basilensis FW507-4G11 0.58 RR42_RS02370 carbon monoxide dehydrogenase 0.14 RR42_RS05325 adenine deaminase — —
Dinoroseobacter shibae DFL-12 0.57 Dshi_2660 (2Fe-2S)-binding domain protein (RefSeq) 0.16 Dshi_0830 Adenosine deaminase (EC 3.5.4.4) (from data) low > 64
Rhodospirillum rubrum S1H 0.56 Rru_A0965 (2Fe-2S)-binding protein (NCBI) 0.14 Rru_A0766 Adenosine deaminase (NCBI) low > 58
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS12260 (2Fe-2S)-binding protein 0.11 ABZR87_RS15055 adenosine deaminase low > 80
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS00485 (2Fe-2S)-binding protein 0.15 QEN71_RS03905 adenosine deaminase low > 153
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS00710 (2Fe-2S)-binding protein 0.13 RALBFv3_RS03155 adenosine deaminase low > 76
Ralstonia solanacearum UW163 0.54 UW163_RS14040 (2Fe-2S)-binding protein 0.13 UW163_RS10570 adenosine deaminase — —
Ralstonia solanacearum GMI1000 0.54 RS_RS07395 (2Fe-2S)-binding protein 0.12 RS_RS10525 adenosine deaminase low > 80
Ralstonia solanacearum PSI07 0.54 RPSI07_RS16790 (2Fe-2S)-binding protein 0.12 RPSI07_RS14155 adenosine deaminase low > 81
Acidovorax sp. GW101-3H11 0.54 Ac3H11_3590 Carbon monoxide dehydrogenase small chain (EC 1.2.99.2) 0.13 Ac3H11_1114 Adenosine deaminase (EC 3.5.4.4) low > 79
Burkholderia phytofirmans PsJN 0.53 BPHYT_RS01770 carbon monoxide dehydrogenase 0.14 BPHYT_RS15095 adenine deaminase — —
Paraburkholderia bryophila 376MFSha3.1 0.53 H281DRAFT_02181 carbon-monoxide dehydrogenase small subunit 0.14 H281DRAFT_03964 adenosine deaminase low > 103
Rhizobium sp. OAE497 0.53 ABIE40_RS17775 (2Fe-2S)-binding protein 0.15 ABIE40_RS00830 adenosine deaminase low > 107
Variovorax sp. OAS795 0.52 ABID97_RS09395 (2Fe-2S)-binding protein 0.14 ABID97_RS22065 adenosine deaminase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.51 GFF5372 Carbon monoxide dehydrogenase small chain (EC 1.2.99.2) 0.14 GFF210 Adenosine deaminase (EC 3.5.4.4) — —
Variovorax sp. SCN45 0.51 GFF6154 Aerobic carbon monoxide dehydrogenase (quinone), small chain (EC 1.2.5.3) 0.15 GFF1862 Adenosine deaminase (EC 3.5.4.4) — —
Sinorhizobium meliloti 1021 0.51 SMc03101 carbon monoxide dehydrogenase small subunit protein 0.16 SMc04120 adenosine deaminase — —
Sphingobium sp. HT1-2 0.44 GFF3360 Aerobic carbon monoxide dehydrogenase (quinone), small chain (EC 1.2.5.3) 0.15 GFF3916 Adenosine deaminase (EC 3.5.4.4) low > 95
Pseudomonas fluorescens FW300-N2C3 0.43 AO356_26655 (2Fe-2S)-binding protein 0.15 AO356_08025 adenosine deaminase low > 104
Klebsiella michiganensis M5al 0.42 BWI76_RS17570 iron-sulfur-binding protein 0.19 BWI76_RS16325 adenosine deaminase low > 92
Pantoea agglomerans CFBP13505 P0401 0.41 PagCFBP13505_RS07680 (2Fe-2S)-binding protein 0.18 PagCFBP13505_RS05765 adenosine deaminase low > 74
Pantoea sp. MT58 0.41 IAI47_19385 (2Fe-2S)-binding protein 0.18 IAI47_10365 adenosine deaminase low > 76
Pseudomonas sp. DMC3 0.40 GFF2804 Nicotinate dehydrogenase subunit A 0.15 GFF3366 Adenine deaminase low > 89
Pseudomonas sp. RS175 0.39 PFR28_01441 Nicotinate dehydrogenase subunit A 0.15 PFR28_05253 Adenine deaminase low > 88
Pseudomonas sp. BP01 0.39 JOY50_RS03175 (2Fe-2S)-binding protein 0.15 JOY50_RS23295 adenosine deaminase low > 84
Pseudomonas putida KT2440 0.38 PP_3947 nicotinate dehydrogenase subunit A 0.14 PP_0591 Adenine deaminase low > 96
Serratia liquefaciens MT49 0.38 IAI46_11840 (2Fe-2S)-binding protein 0.19 IAI46_11540 adenosine deaminase low > 87
Agrobacterium fabrum C58 0.36 Atu5498 oxidoreductase with iron-sulfur subunit 0.16 Atu0136 adenosine deaminase low > 89
Pseudomonas aeruginosa PUPa3 0.36 DQ20_RS53770 (2Fe-2S)-binding protein 0.15 DQ20_RS31560 adenosine deaminase low > 101
Caulobacter crescentus NA1000 0.36 CCNA_00022 putative aerobic-type carbon monoxide dehydrogenase, small subunit CoxS 0.15 CCNA_03284 Adenosine deaminase (EC 3.5.4.4) (from data) low > 66
Pseudomonas aeruginosa PA14 0.36 IKLFDK_07675 (2Fe-2S)-binding protein 0.15 IKLFDK_24800 adenosine deaminase low > 98
Caulobacter crescentus NA1000 Δfur 0.36 CCNA_00022 putative aerobic-type carbon monoxide dehydrogenase, small subunit CoxS 0.15 CCNA_03284 adenosine deaminase low > 67
Pseudomonas aeruginosa MRSN321 0.36 DY961_RS19660 (2Fe-2S)-binding protein 0.15 DY961_RS27020 adenosine deaminase low > 100
Pseudomonas simiae WCS417 0.36 PS417_13030 (2Fe-2S)-binding protein 0.15 PS417_03205 adenine deaminase — —
Pseudomonas fluorescens SBW25 0.36 PFLU_RS13670 (2Fe-2S)-binding protein 0.15 PFLU_RS03285 adenosine deaminase low > 109
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS13670 (2Fe-2S)-binding protein 0.15 PFLU_RS03285 adenosine deaminase low > 109
Pseudomonas orientalis W4I3 0.35 QF045_RS26665 (2Fe-2S)-binding protein 0.15 QF045_RS06245 adenosine deaminase low > 93
Shewanella amazonensis SB2B 0.35 Sama_3438 isoquinoline 1-oxidoreductase, alpha subunit, putative (RefSeq) 0.21 Sama_0085 adenosine deaminase (RefSeq) low > 62
Sphingomonas koreensis DSMZ 15582 0.35 Ga0059261_4049 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs 0.13 Ga0059261_0206 adenosine deaminase low > 68
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_23430 (2Fe-2S)-binding protein 0.15 AO353_06115 adenosine deaminase low > 101
Herbaspirillum seropedicae SmR1 0.34 HSERO_RS06620 (2Fe-2S)-binding protein 0.12 HSERO_RS21260 adenosine deaminase low > 78
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_4583 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) 0.15 Pf1N1B4_1252 Adenosine deaminase (EC 3.5.4.4) — —
Pseudomonas fluorescens GW456-L13 0.33 PfGW456L13_3353 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) 0.15 PfGW456L13_16 Adenosine deaminase (EC 3.5.4.4) — —
Shewanella loihica PV-4 0.33 Shew_2266 2Fe-2S iron-sulfur cluster binding domain-containing protein (RefSeq) 0.18 Shew_3721 adenosine deaminase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.33 SO3049 isoquinoline 1-oxidoreductase, alpha subunit, putative (NCBI ptt file) 0.19 SO4731 add Adenosine deaminase (EC 3.5.4.4) (from data) low > 76
Shewanella sp. ANA-3 0.33 Shewana3_1496 2Fe-2S iron-sulfur cluster binding domain-containing protein (RefSeq) 0.20 Shewana3_4117 adenosine deaminase (RefSeq) low > 73
Escherichia fergusonii Becca 0.32 EFB2_01033 Nicotinate dehydrogenase small FeS subunit 0.19 EFB2_02369 Adenosine deaminase low > 86
Escherichia coli Nissle 1917 0.32 ECOLIN_RS15990 xanthine dehydrogenase iron sulfur-binding subunit XdhC 0.19 ECOLIN_RS09055 adenosine deaminase — —
Pseudomonas fluorescens FW300-N2E2 0.31 Pf6N2E2_5938 Isoquinoline 1-oxidoreductase alpha subunit (EC 1.3.99.16) 0.15 Pf6N2E2_3478 Adenosine deaminase (EC 3.5.4.4) low > 103
Escherichia coli ECOR38 0.31 HEPCGN_18990 xdhC xanthine dehydrogenase iron sulfur-binding subunit XdhC 0.19 HEPCGN_05960 add adenosine deaminase low > 88
Escherichia coli HS(pFamp)R (ATCC 700891) 0.31 OHPLBJKB_00847 Nicotinate dehydrogenase small FeS subunit 0.19 OHPLBJKB_02103 Aminodeoxyfutalosine deaminase low > 74
Alteromonas macleodii MIT1002 0.31 MIT1002_01820 Isoquinoline 1-oxidoreductase subunit alpha 0.17 MIT1002_02946 Adenine deaminase low > 70
Pseudomonas lactucae CFBP13502 0.30 GEMAOFIL_05027 Aldehyde oxidoreductase iron-sulfur-binding subunit PaoA 0.15 GEMAOFIL_00856 Adenine deaminase low > 96
Cellulophaga baltica 18 0.28 M666_RS19530 (2Fe-2S)-binding protein 0.14 M666_RS18835 adenosine deaminase low > 67

Not shown: 21 genomes with orthologs for Rv0374c only; 26 genomes with orthologs for Rv3313c only