Conservation of cofitness between GFF1491 and GFF2877 in Sphingobium sp. HT1-2

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF1491 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 1.0 GFF2877 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) 0.67 6
Hydrogenophaga sp. GW460-11-11-14-LB1 0.61 GFF2719 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 0.31 GFF4348 Enoyl-CoA hydratase (EC 4.2.1.17) — —
Shewanella loihica PV-4 0.59 Shew_1609 6-phosphogluconate dehydrogenase, NAD-binding (RefSeq) 0.28 Shew_1671 enoyl-CoA hydratase/isomerase (RefSeq) low > 60
Variovorax sp. OAS795 0.59 ABID97_RS00265 NAD(P)-dependent oxidoreductase 0.27 ABID97_RS19410 enoyl-CoA hydratase/isomerase family protein low > 91
Shewanella amazonensis SB2B 0.58 Sama_1975 2-hydroxy-3-oxopropionate reductase (RefSeq) 0.22 Sama_1379 enoyl-CoA hydratase/isomerase family protein (RefSeq) low > 62
Sinorhizobium meliloti 1021 0.58 SMc00133 oxidoreductase 0.29 SM_b20752 3-hydroxyisobutyryl-CoA hydrolase low > 103
Shewanella sp. ANA-3 0.58 Shewana3_2554 6-phosphogluconate dehydrogenase, NAD-binding (RefSeq) 0.26 Shewana3_2767 enoyl-CoA hydratase/isomerase (RefSeq) low > 73
Variovorax sp. SCN45 0.58 GFF3739 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 0.27 GFF7380 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) low > 127
Bosea sp. OAE506 0.58 ABIE41_RS21160 NAD(P)-dependent oxidoreductase 0.24 ABIE41_RS19820 enoyl-CoA hydratase/isomerase family protein low > 77
Acidovorax sp. GW101-3H11 0.57 Ac3H11_4470 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 0.34 Ac3H11_2862 Enoyl-CoA hydratase (EC 4.2.1.17) low > 79
Shewanella oneidensis MR-1 0.57 SO2771 garR 2-hydroxy-3-oxopropionate reductase (NCBI ptt file) 0.26 SO1681 enoyl-CoA hydratase/isomerase family protein (NCBI ptt file) low > 76
Pseudomonas sp. S08-1 0.57 OH686_02015 2-hydroxy-3-oxopropionate reductase 0.21 OH686_05880 3-hydroxyisobutyryl-CoA hydrolase low > 80
Pseudomonas segetis P6 0.57 ACVTMO_RS11630 NAD(P)-dependent oxidoreductase 0.22 ACVTMO_RS06840 enoyl-CoA hydratase/isomerase family protein — —
Rhodopseudomonas palustris CGA009 0.56 TX73_010170 NAD(P)-dependent oxidoreductase 0.33 TX73_017840 enoyl-CoA hydratase/isomerase family protein low > 86
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS31100 oxidoreductase 0.35 RR42_RS12795 3-hydroxyisobutyryl-CoA hydrolase low > 128
Rhizobium sp. OAE497 0.56 ABIE40_RS10680 NAD(P)-dependent oxidoreductase 0.31 ABIE40_RS02660 enoyl-CoA hydratase/isomerase family protein low > 107
Pseudomonas aeruginosa PA14 0.55 IKLFDK_07540 oxidoreductase 0.23 IKLFDK_03170 enoyl-CoA hydratase/isomerase family protein low > 98
Pseudomonas aeruginosa MRSN321 0.54 DY961_RS19525 NAD(P)-dependent oxidoreductase 0.24 DY961_RS08785 enoyl-CoA hydratase/isomerase family protein low > 100
Caulobacter crescentus NA1000 Δfur 0.54 CCNA_01645 3-hydroxyisobutyrate dehydrogenase 0.55 CCNA_01414 3-hydroxyisobutyryl-CoA hydrolase low > 67
Caulobacter crescentus NA1000 0.54 CCNA_01645 3-hydroxyisobutyrate dehydrogenase 0.55 CCNA_01414 3-hydroxyisobutyryl-CoA hydrolase low > 66
Pseudomonas aeruginosa PUPa3 0.54 DQ20_RS53640 NAD(P)-dependent oxidoreductase 0.23 DQ20_RS44065 enoyl-CoA hydratase/isomerase family protein low > 101
Marinobacter adhaerens HP15 0.54 HP15_1515 6-phosphogluconate dehydrogenase domain protein 0.27 HP15_3410 enoyl-CoA hydratase/isomerase family protein low > 73
Alteromonas macleodii MIT1002 0.52 MIT1002_01976 2-hydroxy-3-oxopropionate reductase 0.29 MIT1002_01979 Carnitinyl-CoA dehydratase low > 70
Dinoroseobacter shibae DFL-12 0.52 Dshi_3047 6-phosphogluconate dehydrogenase NAD-binding (RefSeq) 0.27 Dshi_1751 Enoyl-CoA hydratase/isomerase (RefSeq) low > 64
Brevundimonas sp. GW460-12-10-14-LB2 0.51 A4249_RS06070 NAD(P)-dependent oxidoreductase 0.57 A4249_RS03590 enoyl-CoA hydratase/isomerase family protein low > 48
Phaeobacter inhibens DSM 17395 0.51 PGA1_c14880 putative 3-hydroxyisobutyrate dehydrogenase 0.28 PGA1_c17350 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) low > 62
Xanthobacter sp. DMC5 0.29 GFF1957 2-hydroxy-3-oxopropionate reductase 0.30 GFF1075 Fatty acid oxidation complex subunit alpha — —
Ralstonia solanacearum IBSBF1503 0.29 RALBFv3_RS04620 NAD(P)-dependent oxidoreductase 0.33 RALBFv3_RS15725 enoyl-CoA hydratase/isomerase family protein — —
Ralstonia sp. UNC404CL21Col 0.29 ABZR87_RS00230 NAD(P)-dependent oxidoreductase 0.34 ABZR87_RS11295 enoyl-CoA hydratase/isomerase family protein low > 80
Ralstonia solanacearum UW163 0.29 UW163_RS09050 NAD(P)-dependent oxidoreductase 0.33 UW163_RS13170 enoyl-CoA hydratase/isomerase family protein — —
Ralstonia solanacearum PSI07 0.29 RPSI07_RS12755 NAD(P)-dependent oxidoreductase 0.33 RPSI07_RS17635 enoyl-CoA hydratase/isomerase family protein — —
Ralstonia solanacearum GMI1000 0.29 RS_RS12190 NAD(P)-dependent oxidoreductase 0.33 RS_RS06505 enoyl-CoA hydratase/isomerase family protein low > 80
Pseudomonas orientalis W4I3 0.28 QF045_RS11500 2-hydroxy-3-oxopropionate reductase 0.33 QF045_RS16115 enoyl-CoA hydratase/isomerase family protein low > 93
Pseudomonas simiae WCS417 0.28 PS417_08800 tartronate semialdehyde reductase 0.34 PS417_13835 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) — —
Pseudomonas lactucae CFBP13502 0.28 GEMAOFIL_01891 2-hydroxy-3-oxopropionate reductase 0.34 GEMAOFIL_02970 Carnitinyl-CoA dehydratase low > 96
Azospirillum brasilense Sp245 0.28 AZOBR_RS07955 tartronate semialdehyde reductase 0.35 AZOBR_RS08460 enoyl-CoA hydratase low > 97
Pseudomonas fluorescens SBW25 0.28 PFLU_RS08860 2-hydroxy-3-oxopropionate reductase 0.35 PFLU_RS14785 enoyl-CoA hydratase/isomerase family protein — —
Pseudomonas fluorescens SBW25-INTG 0.28 PFLU_RS08860 2-hydroxy-3-oxopropionate reductase 0.35 PFLU_RS14785 enoyl-CoA hydratase/isomerase family protein low > 109
Castellaniella sp019104865 MT123 0.28 ABCV34_RS12130 2-hydroxy-3-oxopropionate reductase 0.25 ABCV34_RS03990 enoyl-CoA hydratase/isomerase family protein — —
Pseudomonas sp. BP01 0.27 JOY50_RS00360 2-hydroxy-3-oxopropionate reductase 0.34 JOY50_RS06085 enoyl-CoA hydratase/isomerase family protein low > 84
Pseudomonas putida KT2440 0.27 PP_4299 tartronate semialdehyde reductase 0.34 PP_3491 Enoly-coenzyme A hydratase/isomerase family protein — —
Pseudomonas stutzeri RCH2 0.27 Psest_1179 2-hydroxy-3-oxopropionate reductase 0.31 Psest_2439 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) low > 67
Pseudomonas sp. RS175 0.27 PFR28_03112 2-hydroxy-3-oxopropionate reductase 0.33 PFR28_01887 1,4-dihydroxy-2-naphthoyl-CoA synthase — —
Burkholderia phytofirmans PsJN 0.26 BPHYT_RS08825 tartronate semialdehyde reductase 0.30 BPHYT_RS08630 3-hydroxyisobutyryl-CoA hydrolase low > 109
Pseudomonas fluorescens FW300-N2E2 0.26 Pf6N2E2_5837 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 0.33 Pf6N2E2_1149 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) — —
Pseudomonas sp. SVBP6 0.26 COO64_RS25875 2-hydroxy-3-oxopropionate reductase 0.34 COO64_RS23810 enoyl-CoA hydratase/isomerase family protein low > 93
Paraburkholderia graminis OAS925 0.26 ABIE53_006511 2-hydroxy-3-oxopropionate reductase 0.29 ABIE53_001964 enoyl-CoA hydratase/carnithine racemase — —
Pseudomonas fluorescens FW300-N2C3 0.26 AO356_19610 2-hydroxy-3-oxopropionate reductase 0.32 AO356_26370 crotonase low > 104
Pseudomonas sp. DMC3 0.26 GFF2501 2-hydroxy-3-oxopropionate reductase 0.33 GFF2724 1,4-dihydroxy-2-naphthoyl-CoA synthase low > 89
Paraburkholderia bryophila 376MFSha3.1 0.26 H281DRAFT_00785 2-hydroxy-3-oxopropionate reductase 0.28 H281DRAFT_00756 Enoyl-CoA hydratase/carnithine racemase low > 103
Paraburkholderia sabiae LMG 24235 0.26 QEN71_RS32505 2-hydroxy-3-oxopropionate reductase 0.30 QEN71_RS22700 enoyl-CoA hydratase/isomerase family protein low > 153
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_4297 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 0.34 PfGW456L13_2986 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) low > 87
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_01930 2-hydroxy-3-oxopropionate reductase 0.33 AO353_25665 3-hydroxy-isobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) low > 101
Agrobacterium fabrum C58 0.25 Atu2737 oxidoredutase 0.29 Atu3505 3-hydroxyisobutyryl-CoA hydrolase low > 89
Azospirillum sp. SherDot2 0.23 MPMX19_05813 2-hydroxy-3-oxopropionate reductase 0.33 MPMX19_01209 Carnitinyl-CoA dehydratase low > 112
Pseudomonas fluorescens FW300-N1B4 0.23 Pf1N1B4_3659 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60) 0.31 Pf1N1B4_4790 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) (from data) — —

Not shown: 33 genomes with orthologs for GFF1491 only; 10 genomes with orthologs for GFF2877 only