Conservation of cofitness between ECD_03077 and ECD_03707 in Escherichia coli BL21

64 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03077 glutamate synthase, large subunit 1.0 ECD_03707 methionine biosynthesis regulon transcriptional regulator 0.75 4
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00488 Glutamate synthase [NADPH] large chain 1.00 OHPLBJKB_04223 HTH-type transcriptional regulator MetR low > 73
Escherichia coli ECRC62 1.00 BNILDI_01850 gltB glutamate synthase large subunit 1.00 BNILDI_05070 metR HTH-type transcriptional regulator MetR 0.95 15
Escherichia coli ECOR27 1.00 NOLOHH_09685 gltB glutamate synthase large subunit 1.00 NOLOHH_06460 metR HTH-type transcriptional regulator MetR 0.81 68
Escherichia coli ECRC100 1.00 OKFHMN_17885 gltB glutamate synthase large subunit 1.00 OKFHMN_14330 metR HTH-type transcriptional regulator MetR 0.94 7
Escherichia coli ECRC98 1.00 JDDGAC_21510 gltB glutamate synthase large subunit 1.00 JDDGAC_17955 metR HTH-type transcriptional regulator MetR low > 86
Escherichia coli ECRC102 1.00 NIAGMN_15645 gltB glutamate synthase large subunit 1.00 NIAGMN_12085 metR HTH-type transcriptional regulator MetR
Escherichia coli ECRC101 1.00 MCAODC_08405 gltB glutamate synthase large subunit 1.00 MCAODC_04835 metR HTH-type transcriptional regulator MetR low > 87
Escherichia coli ECOR38 1.00 HEPCGN_16760 gltB3 Glutamate synthase domain 3 1.00 HEPCGN_13030 metR HTH-type transcriptional regulator MetR 0.95 10
Escherichia fergusonii Becca 1.00 EFB2_00611 Glutamate synthase [NADPH] large chain 1.00 EFB2_04809 HTH-type transcriptional regulator MetR low > 86
Escherichia coli ECRC99 1.00 KEDOAH_10265 gltB glutamate synthase large subunit 1.00 KEDOAH_13820 metR HTH-type transcriptional regulator MetR
Escherichia coli BW25113 0.98 b3212 gltB glutamate synthase, large subunit (NCBI) 1.00 b3828 metR DNA-binding transcriptional activator, homocysteine-binding (NCBI) 0.56 9
Escherichia coli Nissle 1917 0.98 ECOLIN_RS18475 glutamate synthase large subunit 1.00 ECOLIN_RS30005 HTH-type transcriptional regulator MetR
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2956 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.92 GFF253 Transcriptional activator MetR low > 78
Klebsiella michiganensis M5al 0.93 BWI76_RS25315 glutamate synthase large subunit 0.88 BWI76_RS01275 LysR family transcriptional regulator 0.44 90
Enterobacter sp. TBS_079 0.93 MPMX20_04126 Glutamate synthase [NADPH] large chain 0.94 MPMX20_04452 HTH-type transcriptional regulator MetR 0.51 75
Enterobacter asburiae PDN3 0.93 EX28DRAFT_3275 Glutamate synthase domain 2 0.94 EX28DRAFT_4493 Transcriptional regulator 0.63 51
Serratia liquefaciens MT49 0.87 IAI46_22345 glutamate synthase large subunit 0.83 IAI46_01030 HTH-type transcriptional regulator MetR 0.78 24
Erwinia tracheiphila SCR3 0.87 LU632_RS21315 gltB glutamate synthase large subunit 0.78 LU632_RS24035 metR HTH-type transcriptional regulator MetR 0.84 26
Pectobacterium carotovorum WPP14 0.87 HER17_RS19910 glutamate synthase large subunit 0.84 HER17_RS20690 HTH-type transcriptional regulator MetR low > 75
Dickeya dadantii 3937 0.86 DDA3937_RS01665 glutamate synthase large subunit 0.87 DDA3937_RS20385 HTH-type transcriptional regulator MetR 0.95 11
Dickeya dianthicola 67-19 0.86 HGI48_RS01560 glutamate synthase large subunit 0.87 HGI48_RS00815 HTH-type transcriptional regulator MetR 0.81 35
Dickeya dianthicola ME23 0.86 DZA65_RS01635 glutamate synthase large subunit 0.87 DZA65_RS00870 HTH-type transcriptional regulator MetR 0.90 12
Rahnella sp. WP5 0.85 EX31_RS12515 glutamate synthase large subunit 0.88 EX31_RS25370 HTH-type transcriptional regulator MetR low > 89
Vibrio cholerae E7946 ATCC 55056 0.74 CSW01_12030 glutamate synthase large subunit 0.55 CSW01_08580 HTH-type transcriptional regulator MetR low > 62
Alteromonas macleodii MIT1002 0.68 MIT1002_03139 Glutamate synthase [NADPH] large chain precursor 0.29 MIT1002_01119 HTH-type transcriptional regulator GltC low > 70
Shewanella loihica PV-4 0.66 Shew_1032 gltB glutamate synthase subunit alpha (RefSeq) 0.35 Shew_2987 LysR family transcriptional regulator (RefSeq) low > 60
Shewanella sp. ANA-3 0.65 Shewana3_3050 gltB glutamate synthase subunit alpha (RefSeq) 0.38 Shewana3_3470 LysR family transcriptional regulator (RefSeq) low > 73
Shewanella amazonensis SB2B 0.65 Sama_0857 gltB glutamate synthase subunit alpha (RefSeq) 0.37 Sama_2628 transcriptional activator protein MetR (RefSeq) 0.84 18
Shewanella oneidensis MR-1 0.65 SO1325 gltB glutamate synthase, large subunit (NCBI ptt file) 0.38 SO0817 metR transcriptional activator protein MetR (NCBI ptt file) 0.85 44
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_3752 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.42 Pf6N2E2_5471 Transcriptional activator MetR low > 103
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_09375 glutamate synthase 0.43 AO356_17735 XRE family transcriptional regulator low > 104
Pseudomonas sp. RS175 0.59 PFR28_05015 Glutamate synthase [NADPH] large chain 0.43 PFR28_03478 HTH-type transcriptional regulator MetR low > 88
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_12515 glutamate synthase 0.42 AO353_16210 XRE family transcriptional regulator low > 101
Pseudomonas stutzeri RCH2 0.59 Psest_3711 Glutamate synthase domain 2 0.43 Psest_1450 Transcriptional regulator
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_272 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.42 PfGW456L13_4778 Transcriptional activator MetR low > 87
Pseudomonas putida KT2440 0.59 PP_5076 L-glutamate synthase(NADPH) alpha subunit 0.42 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding 0.24 67
Pseudomonas fluorescens SBW25 0.59 PFLU_RS02045 glutamate synthase large subunit 0.42 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS02045 glutamate synthase large subunit 0.42 PFLU_RS05540 LysR family transcriptional regulator low > 109
Pseudomonas sp. S08-1 0.59 OH686_10005 Glutamate synthase [NADPH] large chain 0.43 OH686_20465 Transcriptional activator MetR low > 80
Pseudomonas simiae WCS417 0.59 PS417_02000 glutamate synthase 0.42 PS417_05455 XRE family transcriptional regulator 0.42 76
Marinobacter adhaerens HP15 0.58 HP15_482 glutamate synthase subunit alpha 0.33 HP15_458 transcriptional regulator, LysR family protein
Pseudomonas syringae pv. syringae B728a ΔmexB 0.58 Psyr_0411 glutamate synthase (NADPH) large subunit 0.43 Psyr_3917 transcriptional regulator, LysR family low > 86
Pseudomonas syringae pv. syringae B728a 0.58 Psyr_0411 glutamate synthase (NADPH) large subunit 0.43 Psyr_3917 transcriptional regulator, LysR family low > 86
Pseudomonas fluorescens FW300-N1B4 0.58 Pf1N1B4_1534 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.42 Pf1N1B4_784 Transcriptional activator MetR low > 87
Acinetobacter radioresistens SK82 0.56 MPMX26_02808 Glutamate synthase [NADPH] large chain 0.35 MPMX26_01201 HTH-type transcriptional regulator MetR low > 36
Xanthomonas campestris pv. campestris strain 8004 0.50 Xcc-8004.44.1 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.32 Xcc-8004.400.1 Transcriptional activator MetR low > 74
Agrobacterium fabrum C58 0.40 Atu3784 glutamate synthase large subunit 0.29 Atu3827 LysR family transcriptional regulator low > 89
Herbaspirillum seropedicae SmR1 0.40 HSERO_RS19595 glutamate synthase 0.33 HSERO_RS22770 LysR family transcriptional regulator low > 78
Castellaniella sp019104865 MT123 0.40 ABCV34_RS11150 glutamate synthase-related protein 0.38 ABCV34_RS04450 LysR substrate-binding domain-containing protein low > 48
Ralstonia solanacearum UW163 0.40 UW163_RS06700 glutamate synthase subunit alpha 0.35 UW163_RS18860 LysR family transcriptional regulator
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS06915 glutamate synthase subunit alpha 0.35 RALBFv3_RS20315 LysR family transcriptional regulator low > 76
Ralstonia solanacearum PSI07 0.40 RPSI07_RS10320 glutamate synthase subunit alpha 0.36 RPSI07_RS02550 LysR family transcriptional regulator low > 81
Ralstonia sp. UNC404CL21Col 0.40 ABZR87_RS02570 glutamate synthase-related protein 0.35 ABZR87_RS20875 LysR family transcriptional regulator low > 80
Ralstonia solanacearum GMI1000 0.40 RS_RS14860 glutamate synthase subunit alpha 0.36 RS_RS20365 LysR family transcriptional regulator 0.59 18
Mucilaginibacter yixingensis YX-36 DSM 26809 0.40 ABZR88_RS06905 glutamate synthase large subunit 0.20 ABZR88_RS03450 LysR family transcriptional regulator low > 71
Variovorax sp. OAS795 0.39 ABID97_RS23225 glutamate synthase-related protein 0.33 ABID97_RS19400 LysR family transcriptional regulator
Variovorax sp. SCN45 0.39 GFF5332 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.33 GFF4176 Transcriptional activator MetR low > 127
Azospirillum sp. SherDot2 0.39 MPMX19_02657 Glutamate synthase [NADPH] large chain 0.29 MPMX19_00645 HTH-type transcriptional regulator MetR low > 112
Cupriavidus basilensis FW507-4G11 0.39 RR42_RS18990 glutamate synthase 0.34 RR42_RS30655 LysR family transcriptional regulator 0.62 25
Acidovorax sp. GW101-3H11 0.39 Ac3H11_4710 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.35 Ac3H11_2344 Transcriptional activator MetR 0.78 26
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS17855 glutamate synthase 0.36 BPHYT_RS26650 LysR family transcriptional regulator
Paraburkholderia sabiae LMG 24235 0.39 QEN71_RS28010 glutamate synthase-related protein 0.31 QEN71_RS19730 LysR family transcriptional regulator low > 153
Dinoroseobacter shibae DFL-12 0.37 Dshi_0002 Glutamate synthase (ferredoxin) (RefSeq) 0.37 Dshi_2079 transcriptional regulator, LysR family (RefSeq) low > 64
Phaeobacter inhibens DSM 17395 0.37 PGA1_c36100 glutamate synthase [NADPH] large chain 0.37 PGA1_c11710 transcriptional regulator, LysR family 0.72 10

Not shown: 28 genomes with orthologs for ECD_03077 only; 2 genomes with orthologs for ECD_03707 only