| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_19520 | | chemotaxis response regulator protein-glutamate methylesterase | 1.0 | CSW01_19480 | | HlyD family type I secretion periplasmic adaptor subunit | 0.49 | 9 |
| Shewanella loihica PV-4 | 0.48 | Shew_0109 | | response regulator receiver modulated CheB methylesterase (RefSeq) | 0.51 | Shew_0311 | | HlyD family type I secretion membrane fusion protein (RefSeq) | 0.39 | 22 |
| Serratia liquefaciens MT49 | 0.45 | IAI46_16015 | | chemotaxis response regulator protein-glutamate methylesterase | 0.12 | IAI46_08100 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 87 |
| Rahnella sp. WP5 | 0.45 | EX31_RS11360 | | chemotaxis response regulator protein-glutamate methylesterase | 0.25 | EX31_RS19255 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 89 |
| Shewanella amazonensis SB2B | 0.45 | Sama_3499 | | protein-glutamate methylesterase (RefSeq) | 0.48 | Sama_3260 | | HlyD family secretion protein (RefSeq) | low | > 62 |
| Enterobacter sp. TBS_079 | 0.45 | MPMX20_02787 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.25 | MPMX20_02202 | | Type I secretion system membrane fusion protein PrsE | low | > 85 |
| Erwinia amylovora T8 | 0.44 | OLJFJH_12760 | | chemotaxis response regulator protein-glutamate methylesterase | 0.13 | OLJFJH_04725 | | hemolysin D | low | > 58 |
| Pectobacterium carotovorum WPP14 | 0.44 | HER17_RS08120 | | chemotaxis response regulator protein-glutamate methylesterase | 0.38 | HER17_RS05855 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 75 |
| Enterobacter asburiae PDN3 | 0.44 | EX28DRAFT_0673 | | Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain | 0.25 | EX28DRAFT_1343 | | type I secretion membrane fusion protein, HlyD family | low | > 76 |
| Escherichia coli ECRC101 | 0.44 | MCAODC_19255 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.22 | MCAODC_27255 | emrA | hemolysin D | low | > 87 |
| Escherichia coli ECRC99 | 0.44 | KEDOAH_01955 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.22 | KEDOAH_19930 | emrA | hemolysin D | — | — |
| Escherichia coli ECRC102 | 0.44 | NIAGMN_01910 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.22 | NIAGMN_06090 | emrA | hemolysin D | low | > 80 |
| Escherichia coli ECOR38 | 0.44 | HEPCGN_04570 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.22 | HEPCGN_06675 | emrA | hemolysin D | low | > 88 |
| Escherichia coli ECRC98 | 0.44 | JDDGAC_00725 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.22 | JDDGAC_11685 | emrA | hemolysin D | low | > 87 |
| Escherichia coli ECRC100 | 0.44 | OKFHMN_26150 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.22 | OKFHMN_08040 | emrA | hemolysin D | low | > 79 |
| Dechlorosoma suillum PS | 0.44 | Dsui_1713 | | chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain | 0.14 | Dsui_1775 | | type I secretion membrane fusion protein, HlyD family | low | > 51 |
| Escherichia coli Nissle 1917 | 0.44 | ECOLIN_RS10755 | | protein-glutamate methylesterase/protein glutamine deamidase | 0.24 | ECOLIN_RS01695 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 55 |
| Variovorax sp. SCN45 | 0.44 | GFF5767 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.22 | GFF5852 | | Type I secretion membrane fusion protein, HlyD family @ Type I secretion system, membrane fusion protein LapC | low | > 127 |
| Pantoea agglomerans CFBP13505 P0401 | 0.43 | PagCFBP13505_RS02210 | | chemotaxis response regulator protein-glutamate methylesterase | 0.26 | PagCFBP13505_RS00495 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 74 |
| Cupriavidus basilensis FW507-4G11 | 0.43 | RR42_RS35785 | | chemotaxis protein | 0.07 | RR42_RS12720 | | hemolysin D | low | > 128 |
| Burkholderia phytofirmans PsJN | 0.43 | BPHYT_RS18970 | | chemotaxis protein | 0.10 | BPHYT_RS19915 | | hemolysin D | low | > 109 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.43 | GFF1664 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.24 | GFF4153 | | Type I secretion system, membrane fusion protein LapC | low | > 78 |
| Pantoea sp. MT58 | 0.43 | IAI47_08330 | | chemotaxis response regulator protein-glutamate methylesterase | 0.26 | IAI47_06510 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 76 |
| Caulobacter crescentus NA1000 | 0.43 | CCNA_00445 | | receiver domain-glutamate methylesterase cheBI | 0.14 | CCNA_01061 | | type I secretion adaptor protein RsaE | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.43 | CCNA_00445 | | receiver domain-glutamate methylesterase cheBI | 0.14 | CCNA_01061 | | type I secretion adaptor protein RsaE | low | > 67 |
| Methylophilus sp. DMC18 | 0.42 | GFF753 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.34 | GFF461 | | Hemolysin secretion protein D, chromosomal | low | > 43 |
| Azospirillum brasilense Sp245 | 0.42 | AZOBR_RS14260 | | chemotaxis protein | 0.22 | AZOBR_RS18215 | | hypothetical protein | low | > 97 |
| Herbaspirillum seropedicae SmR1 | 0.42 | HSERO_RS10125 | | chemotaxis protein | 0.25 | HSERO_RS09005 | | type I secretion protein HlyD | low | > 78 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.42 | GFF1479 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.23 | GFF2375 | | Type I secretion system, membrane fusion protein LapC | low | > 90 |
| Shewanella oneidensis MR-1 | 0.41 | SO2126 | cheB-1 | protein-glutamate methylesterase CheB (NCBI ptt file) | 0.47 | SO4319 | | HlyD family secretion protein (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.41 | Shewana3_2213 | | response regulator receiver modulated CheB methylesterase (RefSeq) | 0.47 | Shewana3_0380 | | HlyD family type I secretion membrane fusion protein (RefSeq) | low | > 73 |
| Ralstonia solanacearum GMI1000 | 0.41 | RS_RS23895 | | chemotaxis response regulator protein-glutamate methylesterase | 0.21 | RS_RS22840 | | secretion protein HlyD | low | > 80 |
| Acidovorax sp. GW101-3H11 | 0.40 | Ac3H11_1425 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.33 | Ac3H11_2110 | | Type I secretion system, membrane fusion protein LapC | low | > 79 |
| Rhizobium sp. OAE497 | 0.40 | ABIE40_RS02890 | | protein-glutamate O-methylesterase CheB | 0.30 | ABIE40_RS22050 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 107 |
| Agrobacterium fabrum C58 | 0.40 | Atu0519 | | protein-glutamate methylesterase | 0.16 | Atu4414 | | bacteriocin ABC transporter permease | low | > 89 |
| Azospirillum sp. SherDot2 | 0.40 | MPMX19_01953 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.22 | MPMX19_03373 | | Type I secretion system membrane fusion protein PrsE | low | > 112 |
| Pseudomonas aeruginosa PA14 | 0.40 | IKLFDK_24680 | | Protein-glutamate methylesterase/protein-glutamine glutaminase 2 | 0.26 | IKLFDK_09155 | | hemolysin D | low | > 98 |
| Rhodospirillum rubrum S1H | 0.40 | Rru_A1406 | | Two component CheB methylesterase (NCBI) | 0.19 | Rru_B0040 | | Type I secretion membrane fusion protein, HlyD (NCBI) | low | > 58 |
| Pseudomonas aeruginosa PUPa3 | 0.39 | DQ20_RS31680 | | chemotaxis response regulator protein-glutamate methylesterase | 0.26 | DQ20_RS55205 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 101 |
| Pseudomonas aeruginosa MRSN321 | 0.39 | DY961_RS27150 | | chemotaxis response regulator protein-glutamate methylesterase | 0.26 | DY961_RS21135 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 100 |
| Sphingomonas koreensis DSMZ 15582 | 0.39 | Ga0059261_1084 | | Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain | 0.25 | Ga0059261_0542 | | type I secretion membrane fusion protein, HlyD family | low | > 68 |
| Pseudomonas fluorescens SBW25-INTG | 0.38 | PFLU_RS24965 | | chemotaxis response regulator protein-glutamate methylesterase | 0.15 | PFLU_RS15325 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.38 | PFLU_RS24965 | | chemotaxis response regulator protein-glutamate methylesterase | 0.15 | PFLU_RS15325 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 109 |
| Pseudomonas fluorescens FW300-N2E2 | 0.38 | Pf6N2E2_1775 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.37 | Pf6N2E2_2652 | | HlyD family secretion protein | low | > 103 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.37 | DVU1596 | cheB-1 | protein-glutamate methylesterase CheB (TIGR) | 0.34 | DVU1018 | rtxD | type I secretion membrane fusion protein, HlyD family (TIGR) | low | > 55 |
| Pseudomonas syringae pv. syringae B728a | 0.37 | Psyr_0781 | | Protein-glutamate methylesterase | 0.18 | Psyr_0934 | | Type I secretion membrane fusion protein, HlyD | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.37 | Psyr_0781 | | Protein-glutamate methylesterase | 0.18 | Psyr_0934 | | Type I secretion membrane fusion protein, HlyD | low | > 86 |
| Pseudomonas fluorescens FW300-N2C3 | 0.37 | AO356_29840 | | chemotaxis protein CheY | 0.37 | AO356_04080 | | hemolysin secretion protein D | low | > 104 |
| Bosea sp. OAE506 | 0.37 | ABIE41_RS01665 | | chemotaxis response regulator protein-glutamate methylesterase | 0.14 | ABIE41_RS08105 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 77 |
| Pseudomonas stutzeri RCH2 | 0.37 | Psest_0653 | | Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain | 0.35 | Psest_1861 | | type I secretion membrane fusion protein, HlyD family | — | — |
| Pseudomonas sp. RS175 | 0.37 | PFR28_01434 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.37 | PFR28_00781 | | Type I secretion system membrane fusion protein PrsE | low | > 88 |
| Pseudomonas lactucae CFBP13502 | 0.36 | GEMAOFIL_03221 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.34 | GEMAOFIL_00509 | | Type I secretion system membrane fusion protein PrsE | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.36 | DvMF_0465 | | response regulator receiver modulated CheB methylesterase (RefSeq) | 0.33 | DvMF_1159 | | type I secretion membrane fusion protein, HlyD family (RefSeq) | low | > 51 |
| Pseudomonas sp. S08-1 | 0.35 | OH686_21840 | | Chemotaxis response regulator protein-glutamate methylesterase CheB | 0.37 | OH686_20620 | | Type I secretion membrane fusion protein, HlyD family | low | > 80 |
| Magnetospirillum magneticum AMB-1 | 0.29 | AMB_RS01635 | | chemotaxis response regulator protein-glutamate methylesterase | 0.24 | AMB_RS15920 | | HlyD family type I secretion periplasmic adaptor subunit | low | > 64 |
| Phaeobacter inhibens DSM 17395 | 0.18 | PGA1_262p02160 | | putative chemotaxis response regulator protein-glutamate methylesterase | 0.20 | PGA1_c02430 | | type I secretion membrane fusion protein, HlyD family | low | > 62 |
Not shown: 31 genomes with orthologs for CSW01_19520 only; 17 genomes with orthologs for CSW01_19480 only