| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_09955 | | L-asparaginase 1 | 1.0 | CSW01_07190 | | transcriptional regulator FNR | 0.42 | 11 |
| Enterobacter sp. TBS_079 | 0.74 | MPMX20_01849 | | L-asparaginase 1 | 0.85 | MPMX20_02035 | | Fumarate and nitrate reduction regulatory protein | low | > 85 |
| Klebsiella pneumoniae MKP103 | 0.73 | KDGMDA_19250 | | asparaginase | 0.85 | KDGMDA_21005 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 95 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.73 | GFF3482 | | L-asparaginase I, cytoplasmic (EC 3.5.1.1) | 0.85 | GFF2656 | | Fumarate and nitrate reduction regulatory protein | low | > 78 |
| Enterobacter asburiae PDN3 | 0.73 | EX28DRAFT_1768 | | L-asparaginase, type I | 0.84 | EX28DRAFT_1540 | | cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases | low | > 76 |
| Escherichia coli ECRC100 | 0.73 | OKFHMN_26805 | ansA | asparaginase | 0.85 | OKFHMN_02240 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 79 |
| Pantoea sp. MT58 | 0.73 | IAI47_08965 | | asparaginase | 0.85 | IAI47_09580 | | FNR family transcription factor | low | > 76 |
| Escherichia coli ECRC99 | 0.73 | KEDOAH_01305 | ansA | asparaginase | 0.85 | KEDOAH_26530 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | — | — |
| Serratia liquefaciens MT49 | 0.73 | IAI46_14330 | | asparaginase | 0.86 | IAI46_13260 | | FNR family transcription factor | — | — |
| Escherichia coli ECRC62 | 0.73 | BNILDI_16105 | ansA | asparaginase | 0.85 | BNILDI_18090 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 75 |
| Escherichia coli ECOR38 | 0.73 | HEPCGN_05180 | ansA | asparaginase | 0.85 | HEPCGN_25925 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 88 |
| Escherichia coli ECRC101 | 0.73 | MCAODC_18605 | ansA | asparaginase | 0.85 | MCAODC_16030 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 87 |
| Escherichia coli BW25113 | 0.73 | b1767 | ansA | cytoplasmic asparaginase I (NCBI) | 0.85 | b1334 | fnr | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) | 0.15 | 23 |
| Escherichia coli ECOR27 | 0.73 | NOLOHH_17320 | ansA | asparaginase | 0.85 | NOLOHH_19940 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 76 |
| Escherichia coli ECRC102 | 0.73 | NIAGMN_01260 | ansA | asparaginase | 0.85 | NIAGMN_26410 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 80 |
| Pantoea agglomerans CFBP13505 P0401 | 0.73 | PagCFBP13505_RS02800 | | asparaginase | 0.86 | PagCFBP13505_RS06575 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 74 |
| Escherichia coli ECRC98 | 0.73 | JDDGAC_01380 | ansA | asparaginase | 0.85 | JDDGAC_04785 | fnr | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 87 |
| Klebsiella michiganensis M5al | 0.73 | BWI76_RS11580 | | L-asparaginase 1 | 0.85 | BWI76_RS16185 | | transcriptional regulator FNR | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.73 | OHPLBJKB_01965 | | L-asparaginase 1 | 0.85 | OHPLBJKB_02348 | | Fumarate and nitrate reduction regulatory protein | low | > 74 |
| Escherichia coli Nissle 1917 | 0.73 | ECOLIN_RS09860 | | asparaginase | 0.85 | ECOLIN_RS08005 | | fumarate/nitrate reduction transcriptional regulator Fnr | — | — |
| Escherichia fergusonii Becca | 0.73 | EFB2_02227 | | L-asparaginase 1 | 0.85 | EFB2_02593 | | Fumarate and nitrate reduction regulatory protein | low | > 86 |
| Rahnella sp. WP5 | 0.73 | EX31_RS06300 | | asparaginase | 0.86 | EX31_RS07200 | | FNR family transcription factor | low | > 89 |
| Erwinia tracheiphila HP pepo 2.2 | 0.72 | IJEDHG_22635 | ansA | asparaginase | 0.83 | IJEDHG_23150 | crp | transcriptional regulator FNR | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.72 | LU632_RS12975 | ansA | asparaginase | 0.83 | LU632_RS11420 | | FNR family transcription factor | low | > 73 |
| Erwinia amylovora T8 | 0.72 | OLJFJH_13240 | | asparaginase | 0.83 | OLJFJH_13925 | | transcriptional regulator FNR | low | > 58 |
| Dickeya dadantii 3937 | 0.72 | DDA3937_RS10285 | | asparaginase | 0.86 | DDA3937_RS10950 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 74 |
| Pectobacterium carotovorum WPP14 | 0.71 | HER17_RS11110 | | asparaginase | 0.86 | HER17_RS10525 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 75 |
| Dickeya dianthicola 67-19 | 0.71 | HGI48_RS10295 | | asparaginase | 0.86 | HGI48_RS10900 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 71 |
| Dickeya dianthicola ME23 | 0.71 | DZA65_RS10770 | | asparaginase | 0.86 | DZA65_RS11360 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 75 |
| Alteromonas macleodii MIT1002 | 0.71 | MIT1002_01844 | | L-asparaginase 1 | 0.57 | MIT1002_02137 | | Fumarate and nitrate reduction regulatory protein | low | > 70 |
| Shewanella loihica PV-4 | 0.69 | Shew_1940 | ansA | cytoplasmic asparaginase I (RefSeq) | 0.76 | Shew_1993 | | fumarate/nitrate reduction transcriptional regulator (RefSeq) | — | — |
| Shewanella amazonensis SB2B | 0.68 | Sama_1722 | ansA | cytoplasmic asparaginase I (RefSeq) | 0.76 | Sama_1799 | | fumarate/nitrate reduction transcriptional regulator (RefSeq) | low | > 62 |
| Shewanella oneidensis MR-1 | 0.68 | SO2421 | ansA | L-asparaginase I (NCBI ptt file) | 0.76 | SO2356 | etrA | electron transport regulator a (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.68 | Shewana3_1963 | ansA | cytoplasmic asparaginase I (RefSeq) | 0.77 | Shewana3_2115 | | fumarate/nitrate reduction transcriptional regulator (RefSeq) | — | — |
| Kangiella aquimarina DSM 16071 | 0.55 | B158DRAFT_1792 | | L-asparaginases, type I | 0.56 | B158DRAFT_1982 | | cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases | low | > 40 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.34 | Echvi_0080 | | L-asparaginases, type I | 0.17 | Echvi_2881 | | cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases | low | > 79 |
| Azospirillum sp. SherDot2 | 0.32 | MPMX19_00090 | | L-asparaginase 1 | 0.26 | MPMX19_00212 | | Nitrogen fixation regulation protein FixK | low | > 112 |
| Pseudomonas sp. S08-1 | 0.29 | OH686_13275 | | L-asparaginase I, cytoplasmic | 0.53 | OH686_02245 | | Fumarate and nitrate reduction regulatory protein | low | > 80 |
| Pseudomonas stutzeri RCH2 | 0.28 | Psest_4078 | | L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D | 0.53 | Psest_2538 | | cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases | low | > 67 |
| Pseudomonas fluorescens FW300-N1B4 | 0.27 | Pf1N1B4_2023 | | L-asparaginase (EC 3.5.1.1) (from data) | 0.53 | Pf1N1B4_3867 | | Fumarate and nitrate reduction regulatory protein | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.27 | AO353_09960 | | L-asparaginase (EC 3.5.1.1) (from data) | 0.53 | AO353_00660 | | transcriptional regulator | low | > 101 |
| Pseudomonas simiae WCS417 | 0.27 | PS417_28140 | | asparaginase | 0.53 | PS417_20785 | | transcriptional regulator | low | > 88 |
| Pseudomonas segetis P6 | 0.26 | MPMX49_00165 | | L-asparaginase 1 | 0.54 | MPMX49_02303 | | Transcriptional activator protein Anr | low | > 75 |
| Pseudomonas fluorescens GW456-L13 | 0.26 | PfGW456L13_740 | | L-asparaginase (EC 3.5.1.1) (from data) | 0.54 | PfGW456L13_4071 | | Fumarate and nitrate reduction regulatory protein | low | > 87 |
| Pseudomonas fluorescens FW300-N2E2 | 0.26 | Pf6N2E2_4087 | | L-asparaginase (EC 3.5.1.1) (from data) | 0.53 | Pf6N2E2_2323 | | Fumarate and nitrate reduction regulatory protein | low | > 103 |
| Pseudomonas sp. DMC3 | 0.26 | GFF490 | | L-asparaginase 1 | 0.54 | GFF711 | | Transcriptional activator protein Anr | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.26 | Psyr_5053 | | asparaginase | 0.54 | Psyr_3425 | | Cyclic nucleotide-binding:Bacterial regulatory protein, Crp | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.26 | AO356_11100 | | L-asparaginase (EC 3.5.1.1) (from data) | 0.53 | AO356_02485 | | transcriptional regulator | low | > 104 |
| Pseudomonas syringae pv. syringae B728a | 0.26 | Psyr_5053 | | asparaginase | 0.54 | Psyr_3425 | | Cyclic nucleotide-binding:Bacterial regulatory protein, Crp | low | > 86 |
| Pseudomonas orientalis W4I3 | 0.26 | QF045_RS02500 | | asparaginase | 0.53 | QF045_RS22590 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 93 |
| Pseudomonas lactucae CFBP13502 | 0.26 | GEMAOFIL_00094 | | L-asparaginase 1 | 0.53 | GEMAOFIL_04302 | | Transcriptional activator protein Anr | — | — |
| Pseudomonas sp. RS175 | 0.25 | PFR28_04501 | | L-asparaginase 1 | 0.53 | PFR28_01079 | | Transcriptional activator protein Anr | — | — |
| Pseudomonas putida KT2440 | 0.25 | PP_0495 | | type 1 L-asparaginase | 0.52 | PP_4265 | | DNA-binding transcriptional dual regulator | low | > 96 |
| Pseudomonas aeruginosa PA14 | 0.25 | IKLFDK_11055 | | asparaginase | 0.53 | IKLFDK_07375 | | transcriptional regulator Anr | low | > 98 |
| Pseudomonas aeruginosa MRSN321 | 0.25 | DY961_RS17645 | | asparaginase | 0.53 | DY961_RS19345 | anr;inference=COORDINATES | transcriptional regulator Anr | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.25 | DQ20_RS39875 | | asparaginase | 0.53 | DQ20_RS53475 | anr;inference=COORDINATES | transcriptional regulator Anr | low | > 101 |
| Pseudomonas sp. SVBP6 | 0.25 | COO64_RS15980 | | asparaginase | 0.52 | COO64_RS18640 | fnrA | Crp/Fnr family transcriptional regulator FnrA | low | > 93 |
| Pseudomonas sp. BP01 | 0.24 | JOY50_RS20220 | | asparaginase | 0.52 | JOY50_RS00125 | fnrA | Crp/Fnr family transcriptional regulator FnrA | low | > 84 |
| Pseudomonas fluorescens SBW25 | 0.24 | PFLU_RS29825 | | asparaginase | 0.53 | PFLU_RS22395 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.24 | PFLU_RS29825 | | asparaginase | 0.53 | PFLU_RS22395 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.13 | H281DRAFT_00783 | | L-asparaginase | 0.36 | H281DRAFT_01640 | | transcriptional regulator, Crp/Fnr family | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.13 | ABIE53_001995 | | L-asparaginase | 0.35 | ABIE53_004332 | | CRP/FNR family transcriptional regulator | low | > 113 |
| Burkholderia phytofirmans PsJN | 0.12 | BPHYT_RS08815 | | L-asparaginase (EC 3.5.1.1) (from data) | 0.38 | BPHYT_RS31300 | | Crp/Fnr family transcriptional regulator | low | > 109 |
| Ralstonia solanacearum IBSBF1503 | 0.11 | RALBFv3_RS15770 | | asparaginase | 0.38 | RALBFv3_RS15650 | | fumarate/nitrate reduction transcriptional regulator Fnr | — | — |
| Ralstonia solanacearum UW163 | 0.11 | UW163_RS13215 | | asparaginase | 0.38 | UW163_RS13110 | | fumarate/nitrate reduction transcriptional regulator Fnr | — | — |
| Ralstonia sp. UNC404CL21Col | 0.11 | ABZR87_RS11340 | | asparaginase | 0.39 | ABZR87_RS11180 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 80 |
| Ralstonia solanacearum PSI07 | 0.11 | RPSI07_RS17595 | | asparaginase | 0.38 | RPSI07_RS17705 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 81 |
| Variovorax sp. SCN45 | 0.11 | GFF356 | | L-asparaginase (EC 3.5.1.1) | 0.22 | GFF6947 | | transcriptional regulator, Crp/Fnr family | low | > 127 |
| Ralstonia solanacearum GMI1000 | 0.11 | RS_RS06550 | | asparaginase | 0.38 | RS_RS06430 | | fumarate/nitrate reduction transcriptional regulator Fnr | low | > 80 |
| Paraburkholderia sabiae LMG 24235 | 0.11 | QEN71_RS22565 | | asparaginase | 0.38 | QEN71_RS17975 | | helix-turn-helix domain-containing protein | low | > 153 |
| Agrobacterium fabrum C58 | 0.10 | Atu3791 | | L-asparaginase | 0.19 | Atu1602 | | transcriptional activator, Crp family | low | > 89 |
| Cupriavidus basilensis FW507-4G11 | 0.10 | RR42_RS12610 | | glutaminase | 0.40 | RR42_RS12875 | | transcriptional regulator | low | > 128 |
| Acidovorax sp. GW101-3H11 | 0.09 | Ac3H11_2391 | | L-asparaginase (EC 3.5.1.1) | 0.38 | Ac3H11_975 | | transcriptional regulator, Crp/Fnr family | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.08 | GFF4502 | | L-asparaginase (EC 3.5.1.1) | 0.39 | GFF4142 | | transcriptional regulator, Crp/Fnr family | low | > 90 |
Not shown: 16 genomes with orthologs for CSW01_09955 only; 22 genomes with orthologs for CSW01_07190 only