Conservation of cofitness between CSW01_11765 and CSW01_07075 in Vibrio cholerae E7946 ATCC 55056

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11765 amino-acid N-acetyltransferase 1.0 CSW01_07075 MFS transporter 0.69 2
Serratia liquefaciens MT49 0.65 IAI46_20395 amino-acid N-acetyltransferase 0.36 IAI46_20005 multidrug efflux MFS transporter permease subunit EmrB low > 86
Erwinia tracheiphila SCR3 0.65 LU632_RS06210 argA amino-acid N-acetyltransferase 0.23 LU632_RS09490 DHA2 family efflux MFS transporter permease subunit low > 74
Erwinia tracheiphila HP pepo 2.2 0.65 IJEDHG_17225 argA amino-acid N-acetyltransferase 0.23 IJEDHG_19965 EmrB/QacA family drug resistance transporter low > 61
Pectobacterium carotovorum WPP14 0.65 HER17_RS16505 amino-acid N-acetyltransferase 0.37 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB low > 75
Erwinia amylovora T8 0.65 OLJFJH_09115 amino-acid N-acetyltransferase 0.36 OLJFJH_09800 multidrug efflux MFS transporter permease subunit EmrB low > 58
Pantoea sp. MT58 0.64 IAI47_03975 amino-acid N-acetyltransferase 0.38 IAI47_04495 multidrug efflux MFS transporter permease subunit EmrB low > 76
Pantoea agglomerans CFBP13505 P0401 0.64 PagCFBP13505_RS16990 amino-acid N-acetyltransferase 0.38 PagCFBP13505_RS14490 multidrug efflux MFS transporter permease subunit EmrB low > 74
Enterobacter asburiae PDN3 0.64 EX28DRAFT_2893 N-acetylglutamate synthase (EC 2.3.1.1) 0.53 EX28DRAFT_2615 drug resistance transporter, EmrB/QacA subfamily low > 76
Enterobacter sp. TBS_079 0.64 MPMX20_03681 Amino-acid acetyltransferase 0.39 MPMX20_03564 Multidrug export protein EmrB low > 85
Rahnella sp. WP5 0.64 EX31_RS13160 amino-acid N-acetyltransferase 0.37 EX31_RS13660 multidrug efflux MFS transporter permease subunit EmrB low > 89
Dickeya dianthicola ME23 0.64 DZA65_RS05340 amino-acid N-acetyltransferase 0.38 DZA65_RS17910 multidrug efflux MFS transporter permease subunit EmrB low > 75
Dickeya dianthicola 67-19 0.64 HGI48_RS05000 amino-acid N-acetyltransferase 0.38 HGI48_RS16835 multidrug efflux MFS transporter permease subunit EmrB low > 71
Klebsiella pneumoniae MKP103 0.64 KDGMDA_03795 amino-acid N-acetyltransferase 0.39 KDGMDA_02765 multidrug efflux MFS transporter permease subunit EmrB low > 95
Dickeya dadantii 3937 0.63 DDA3937_RS04990 amino-acid N-acetyltransferase 0.37 DDA3937_RS16765 multidrug efflux MFS transporter permease subunit EmrB low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.63 GFF1299 N-acetylglutamate synthase (EC 2.3.1.1) 0.38 GFF1593 Multidrug resistance protein B low > 78
Klebsiella michiganensis M5al 0.63 BWI76_RS23220 amino-acid N-acetyltransferase 0.39 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB low > 92
Escherichia fergusonii Becca 0.63 EFB2_01066 Amino-acid acetyltransferase 0.37 EFB2_01242 Multidrug export protein EmrB low > 86
Escherichia coli BW25113 0.63 b2818 argA N-acetylglutamate synthase (NCBI) 0.37 b2686 emrB multidrug efflux system protein (NCBI) low > 76
Escherichia coli Nissle 1917 0.63 ECOLIN_RS15820 amino-acid N-acetyltransferase 0.37 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB low > 55
Escherichia coli ECRC100 0.63 OKFHMN_20060 argA amino-acid N-acetyltransferase 0.37 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB low > 79
Escherichia coli ECRC102 0.63 NIAGMN_17830 argA amino-acid N-acetyltransferase 0.37 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB low > 80
Escherichia coli ECRC62 0.63 BNILDI_10425 argA amino-acid N-acetyltransferase 0.37 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB low > 75
Escherichia coli ECRC99 0.63 KEDOAH_08070 argA amino-acid N-acetyltransferase 0.37 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB — —
Escherichia coli BL21 0.63 ECD_02666 amino acid N-acetyltransferase and inactive acetylglutamate kinase 0.37 ECD_02541 multidrug efflux system protein low > 61
Escherichia coli ECRC98 0.63 JDDGAC_23725 argA amino-acid N-acetyltransferase 0.37 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB low > 87
Escherichia coli ECOR38 0.63 HEPCGN_19315 argA amino-acid N-acetyltransferase 0.37 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB low > 88
Escherichia coli HS(pFamp)R (ATCC 700891) 0.63 OHPLBJKB_00912 Amino-acid acetyltransferase 0.37 OHPLBJKB_01047 Multidrug export protein EmrB low > 74
Escherichia coli ECOR27 0.63 NOLOHH_11945 argA amino-acid N-acetyltransferase 0.37 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB low > 76
Escherichia coli ECRC101 0.63 MCAODC_10585 argA amino-acid N-acetyltransferase 0.37 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB low > 88
Shewanella amazonensis SB2B 0.61 Sama_0330 N-acetylglutamate synthase (RefSeq) 0.21 Sama_0403 drug resistance transporter, EmrB/QacA family protein (RefSeq) low > 62
Shewanella oneidensis MR-1 0.61 SO4245 argA amino-acid acetyltransferase (NCBI ptt file) 0.21 SO0525 drug resistance transporter, EmrB/QacA family protein (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.61 Shew_3478 N-acetylglutamate synthase (RefSeq) 0.21 Shew_3405 EmrB/QacA family drug resistance transporter (RefSeq) low > 60
Acinetobacter baumannii LAC-4 0.48 RR41_RS18750 amino-acid N-acetyltransferase 0.50 RR41_RS14740 DHA2 family efflux MFS transporter permease subunit low > 55
Acinetobacter radioresistens SK82 0.47 MPMX26_00029 Amino-acid acetyltransferase 0.47 MPMX26_02394 Multidrug export protein EmrB low > 36
Pseudomonas sp. SVBP6 0.47 COO64_RS00915 argA amino-acid N-acetyltransferase 0.37 COO64_RS08900 DHA2 family efflux MFS transporter permease subunit low > 93
Pseudomonas sp. RS175 0.47 PFR28_04308 Amino-acid acetyltransferase 0.37 PFR28_02747 Multidrug export protein EmrB low > 88
Pseudomonas putida KT2440 0.47 PP_5185 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase 0.38 PP_3548 multidrug efflux transport system - permease subunit low > 96
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_4497 N-acetylglutamate synthase (EC 2.3.1.1) 0.37 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system — —
Pseudomonas sp. BP01 0.47 JOY50_RS22370 argA amino-acid N-acetyltransferase 0.38 JOY50_RS28120 DHA2 family efflux MFS transporter permease subunit — —
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_13085 N-acetylglutamate synthase 0.38 AO356_01025 multidrug resistance protein B low > 104
Pseudomonas aeruginosa PA14 0.46 IKLFDK_27450 amino-acid N-acetyltransferase 0.36 IKLFDK_27690 MFS transporter low > 100
Pseudomonas segetis P6 0.46 MPMX49_04449 Amino-acid acetyltransferase 0.38 MPMX49_02243 Multidrug export protein EmrB — —
Pseudomonas sp. S08-1 0.46 OH686_11120 amino-acid N-acetyltransferase 0.21 OH686_04570 Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system low > 80
Pseudomonas simiae WCS417 0.46 PS417_27195 N-acetylglutamate synthase 0.38 PS417_16910 multidrug resistance protein B low > 88
Pseudomonas sp. DMC3 0.46 GFF301 Amino-acid acetyltransferase 0.37 GFF1488 Multidrug export protein EmrB low > 89
Pseudomonas fluorescens SBW25-INTG 0.46 PFLU_RS28855 amino-acid N-acetyltransferase 0.38 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit — —
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_0254 N-acetylglutamate synthase 0.37 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_0254 N-acetylglutamate synthase 0.37 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily — —
Pseudomonas fluorescens SBW25 0.46 PFLU_RS28855 amino-acid N-acetyltransferase 0.38 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit — —
Pseudomonas lactucae CFBP13502 0.46 GEMAOFIL_05578 Amino-acid acetyltransferase 0.37 GEMAOFIL_03697 Multidrug export protein EmrB low > 93
Pseudomonas fluorescens FW300-N1B4 0.45 Pf1N1B4_2243 N-acetylglutamate synthase (EC 2.3.1.1) 0.37 Pf1N1B4_4002 Inner membrane component of tripartite multidrug resistance system — —
Pseudomonas fluorescens GW456-L13 0.45 PfGW456L13_913 N-acetylglutamate synthase (EC 2.3.1.1) 0.37 PfGW456L13_2606 Inner membrane component of tripartite multidrug resistance system low > 87
Pseudomonas fluorescens FW300-N2E3 0.45 AO353_08685 N-acetylglutamate synthase 0.37 AO353_27840 multidrug resistance protein B low > 101
Variovorax sp. SCN45 0.44 GFF249 N-acetylglutamate synthase (EC 2.3.1.1) 0.43 GFF4771 Multidrug efflux system EmrAB-OMF, inner-membrane proton/drug antiporter EmrB (MFS type) — —
Variovorax sp. OAS795 0.43 ABID97_RS16620 amino-acid N-acetyltransferase 0.42 ABID97_RS20390 DHA2 family efflux MFS transporter permease subunit — —
Methylophilus sp. DMC18 0.43 GFF2486 Amino-acid acetyltransferase 0.10 GFF1957 Riboflavin transporter RibZ — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.42 GFF4300 N-acetylglutamate synthase (EC 2.3.1.1) 0.41 GFF3757 Inner membrane component of tripartite multidrug resistance system low > 90
Acidovorax sp. GW101-3H11 0.42 Ac3H11_900 N-acetylglutamate synthase (EC 2.3.1.1) 0.40 Ac3H11_2352 Inner membrane component of tripartite multidrug resistance system — —
Ralstonia solanacearum PSI07 0.40 RPSI07_RS17870 amino-acid N-acetyltransferase 0.40 RPSI07_RS17660 MFS transporter low > 81
Cupriavidus basilensis FW507-4G11 0.40 RR42_RS13035 amino acid acetyltransferase 0.39 RR42_RS12830 multidrug resistance protein B — —
Ralstonia solanacearum GMI1000 0.40 RS_RS06265 amino-acid N-acetyltransferase 0.55 RS_RS09355 MFS transporter — —
Ralstonia solanacearum UW163 0.40 UW163_RS12945 amino-acid N-acetyltransferase 0.17 UW163_RS07870 MFS transporter — —
Ralstonia solanacearum IBSBF1503 0.40 RALBFv3_RS15485 amino-acid N-acetyltransferase 0.41 RALBFv3_RS15695 MFS transporter low > 76
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS17320 amino acid acetyltransferase 0.64 HSERO_RS16355 DSBA oxidoreductase — —
Ralstonia sp. UNC404CL21Col 0.39 ABZR87_RS11015 amino-acid N-acetyltransferase 0.41 ABZR87_RS11225 DHA2 family efflux MFS transporter permease subunit low > 80
Paraburkholderia sabiae LMG 24235 0.39 QEN71_RS05620 amino-acid N-acetyltransferase 0.38 QEN71_RS23085 DHA2 family efflux MFS transporter permease subunit — —
Castellaniella sp019104865 MT123 0.38 ABCV34_RS02415 amino-acid N-acetyltransferase 0.40 ABCV34_RS05950 DHA2 family efflux MFS transporter permease subunit — —
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_00444 N-acetylglutamate synthase 0.41 H281DRAFT_02341 MFS transporter, DHA2 family, multidrug resistance protein low > 103
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS12985 amino acid acetyltransferase 0.42 BPHYT_RS19670 DSBA oxidoreductase low > 109
Paraburkholderia graminis OAS925 0.37 ABIE53_002814 amino-acid N-acetyltransferase 0.42 ABIE53_000311 DHA2 family multidrug resistance protein — —

Not shown: 5 genomes with orthologs for CSW01_11765 only; 31 genomes with orthologs for CSW01_07075 only