Conservation of cofitness between CSW01_13865 and CSW01_04595 in Vibrio cholerae E7946 ATCC 55056

73 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_13865 nitrogen regulation protein NR(I) 1.0 CSW01_04595 DUF423 domain-containing protein 0.44 8
Enterobacter asburiae PDN3 0.73 EX28DRAFT_4350 nitrogen regulation protein NR(I) 0.26 EX28DRAFT_2882 Uncharacterized small membrane protein low > 76
Enterobacter sp. TBS_079 0.73 MPMX20_04597 DNA-binding transcriptional regulator NtrC 0.27 MPMX20_03670 hypothetical protein low > 85
Escherichia fergusonii Becca 0.72 EFB2_04748 DNA-binding transcriptional regulator NtrC 0.27 EFB2_01110 hypothetical protein low > 86
Serratia liquefaciens MT49 0.72 IAI46_24960 nitrogen regulation protein NR(I) 0.25 IAI46_20335 DUF423 domain-containing protein low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF2220 Nitrogen regulation protein NR(I) 0.28 GFF4864 COG2363 low > 78
Escherichia coli ECRC102 0.72 NIAGMN_11865 glnG nitrogen regulation protein NR(I) 0.27 NIAGMN_17895 ygdD UPF0382 inner membrane protein YgdD low > 80
Escherichia coli ECRC98 0.72 JDDGAC_17735 glnG nitrogen regulation protein NR(I) 0.27 JDDGAC_23790 ygdD UPF0382 inner membrane protein YgdD — —
Escherichia coli ECOR27 0.72 NOLOHH_06240 glnG nitrogen regulation protein NR(I) 0.27 NOLOHH_12005 ygdD UPF0382 inner membrane protein YgdD low > 76
Escherichia coli ECRC101 0.72 MCAODC_04610 glnG nitrogen regulation protein NR(I) 0.27 MCAODC_10650 ygdD UPF0382 inner membrane protein YgdD low > 87
Escherichia coli Nissle 1917 0.72 ECOLIN_RS22295 nitrogen regulation protein NR(I) 0.27 ECOLIN_RS15645 DUF423 domain-containing protein low > 55
Escherichia coli ECRC100 0.72 OKFHMN_14110 glnG nitrogen regulation protein NR(I) 0.27 OKFHMN_20125 ygdD UPF0382 inner membrane protein YgdD low > 79
Escherichia coli ECRC99 0.72 KEDOAH_14040 glnG nitrogen regulation protein NR(I) 0.27 KEDOAH_08005 ygdD UPF0382 inner membrane protein YgdD — —
Escherichia coli BW25113 0.72 b3868 glnG fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) 0.27 b2807 ygdD conserved inner membrane protein (NCBI) low > 76
Escherichia coli ECRC62 0.72 BNILDI_05290 glnG nitrogen regulation protein NR(I) 0.27 BNILDI_10510 ygdD UPF0382 inner membrane protein YgdD low > 75
Klebsiella pneumoniae MKP103 0.72 KDGMDA_09000 nitrogen regulation protein NR(I) 0.26 KDGMDA_03510 DUF423 domain-containing protein low > 95
Klebsiella michiganensis M5al 0.72 BWI76_RS00385 nitrogen assimilation regulatory protein 0.26 BWI76_RS22950 membrane protein low > 92
Escherichia coli BL21 0.72 ECD_03753 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein 0.27 ECD_02658 UPF0382 family inner membrane protein low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 0.72 OHPLBJKB_04184 DNA-binding transcriptional regulator NtrC 0.27 OHPLBJKB_00924 hypothetical protein low > 74
Escherichia coli ECOR38 0.72 HEPCGN_12740 glnG nitrogen regulation protein NR(I) 0.27 HEPCGN_19380 ygdD DUF423 domain-containing protein low > 88
Rahnella sp. WP5 0.72 EX31_RS15880 nitrogen regulation protein NR(I) 0.28 EX31_RS13105 DUF423 domain-containing protein low > 89
Pantoea sp. MT58 0.72 IAI47_00450 nitrogen regulation protein NR(I) 0.25 IAI47_04030 DUF423 domain-containing protein low > 76
Erwinia amylovora T8 0.72 OLJFJH_05495 nitrogen regulation protein NR(I) 0.24 OLJFJH_09175 DUF423 domain-containing protein low > 58
Pantoea agglomerans CFBP13505 P0401 0.71 PagCFBP13505_RS18895 nitrogen regulation protein NR(I) 0.25 PagCFBP13505_RS16940 DUF423 domain-containing protein low > 74
Pectobacterium carotovorum WPP14 0.71 HER17_RS21440 nitrogen regulation protein NR(I) 0.29 HER17_RS16410 DUF423 domain-containing protein low > 75
Dickeya dadantii 3937 0.71 DDA3937_RS00125 nitrogen regulation protein NR(I) 0.31 DDA3937_RS05055 DUF423 domain-containing protein low > 74
Dickeya dianthicola ME23 0.71 DZA65_RS22210 nitrogen regulation protein NR(I) 0.28 DZA65_RS05395 DUF423 domain-containing protein low > 75
Dickeya dianthicola 67-19 0.71 HGI48_RS21235 nitrogen regulation protein NR(I) 0.28 HGI48_RS05055 DUF423 domain-containing protein low > 71
Shewanella oneidensis MR-1 0.69 SO4472 ntrC nitrogen regulation protein NR(I) (NCBI ptt file) 0.34 SO1535 conserved hypothetical protein (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.69 Sama_3427 response regulator receiver protein (RefSeq) 0.34 Sama_2427 hypothetical protein (RefSeq) low > 62
Shewanella sp. ANA-3 0.69 Shewana3_0258 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) 0.34 Shewana3_2892 hypothetical protein (RefSeq) low > 73
Shewanella loihica PV-4 0.69 Shew_3561 nitrogen metabolism transcriptional regulator, NtrC, Fis family (RefSeq) 0.41 Shew_2762 hypothetical protein (RefSeq) — —
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_12145 nitrogen regulation protein NR(I) 0.33 AO353_08225 hypothetical protein low > 101
Pseudomonas fluorescens SBW25-INTG 0.66 PFLU_RS01685 nitrogen regulation protein NR(I) 0.38 PFLU_RS28430 DUF423 domain-containing protein low > 109
Pseudomonas fluorescens FW300-N2C3 0.66 AO356_09730 nitrogen regulation protein NR(I) 0.32 AO356_13365 hypothetical protein low > 104
Pseudomonas fluorescens FW300-N1B4 0.66 Pf1N1B4_1611 Nitrogen regulation protein NR(I) 0.32 Pf1N1B4_2329 COG2363 low > 87
Pseudomonas putida KT2440 0.66 PP_5048 two-component system DNA-binding transcriptional dual regulator GlnL/GlnG 0.34 PP_5106 conserved inner membrane protein low > 96
Pseudomonas fluorescens GW456-L13 0.66 PfGW456L13_347 Nitrogen regulation protein NR(I) 0.35 PfGW456L13_998 COG2363 low > 87
Pseudomonas simiae WCS417 0.66 PS417_01635 nitrogen regulation protein NR(I) 0.37 PS417_26785 membrane protein low > 88
Pseudomonas lactucae CFBP13502 0.66 GEMAOFIL_00547 DNA-binding transcriptional regulator NtrC 0.36 GEMAOFIL_05494 hypothetical protein low > 96
Pseudomonas segetis P6 0.66 MPMX49_04287 DNA-binding transcriptional regulator NtrC 0.40 MPMX49_04409 hypothetical protein low > 75
Pseudomonas fluorescens SBW25 0.66 PFLU_RS01685 nitrogen regulation protein NR(I) 0.38 PFLU_RS28430 DUF423 domain-containing protein low > 109
Pseudomonas sp. DMC3 0.66 GFF4081 DNA-binding transcriptional regulator NtrC 0.38 GFF221 hypothetical protein low > 89
Pseudomonas fluorescens FW300-N2E2 0.66 Pf6N2E2_3826 Nitrogen regulation protein NR(I) 0.34 Pf6N2E2_4588 COG2363 low > 103
Pseudomonas sp. BP01 0.66 JOY50_RS09450 ntrC nitrogen regulation protein NR(I) 0.33 JOY50_RS20850 DUF423 domain-containing protein low > 84
Pseudomonas orientalis W4I3 0.66 QF045_RS04705 nitrogen regulation protein NR(I) 0.32 QF045_RS01185 DUF423 domain-containing protein — —
Pseudomonas syringae pv. syringae B728a 0.66 Psyr_4822 Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) 0.37 Psyr_4742 Protein of unknown function DUF423 — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.66 Psyr_4822 Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) 0.37 Psyr_4742 Protein of unknown function DUF423 — —
Pseudomonas sp. SVBP6 0.66 COO64_RS13325 ntrC nitrogen regulation protein NR(I) 0.28 COO64_RS12940 DUF423 domain-containing protein low > 93
Pseudomonas sp. S08-1 0.66 OH686_10640 nitrogen regulation protein NR(I) 0.36 OH686_14275 hypothetical regulator low > 80
Pseudomonas sp. RS175 0.66 PFR28_04944 DNA-binding transcriptional regulator NtrC 0.33 PFR28_04254 hypothetical protein low > 88
Pseudomonas aeruginosa PUPa3 0.66 DQ20_RS50645 ntrC;inference=COORDINATES two-component system response regulator NtrC 0.38 DQ20_RS37425 DUF423 domain-containing protein low > 101
Pseudomonas aeruginosa MRSN321 0.66 DY961_RS11455 ntrC;inference=COORDINATES two-component system response regulator NtrC 0.38 DY961_RS21870 DUF423 domain-containing protein low > 100
Pseudomonas aeruginosa PA14 0.66 IKLFDK_27895 two-component system response regulator NtrC 0.38 IKLFDK_23530 DUF423 domain-containing protein low > 98
Pseudomonas stutzeri RCH2 0.65 Psest_3932 nitrogen regulation protein NR(I) 0.37 Psest_0265 Uncharacterized small membrane protein low > 67
Marinobacter adhaerens HP15 0.65 HP15_425 two-component response regulator NtrC 0.35 HP15_3276 membrane protein containing DUF423 — —
Acinetobacter radioresistens SK82 0.65 MPMX26_01292 DNA-binding transcriptional regulator NtrC 0.25 MPMX26_01109 hypothetical protein low > 36
Acinetobacter baumannii LAC-4 0.64 RR41_RS08030 nitrogen regulation protein NR(I) 0.21 RR41_RS06285 DUF423 domain-containing protein low > 55
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS15680 chemotaxis protein CheY 0.38 HSERO_RS06075 membrane protein low > 78
Castellaniella sp019104865 MT123 0.49 ABCV34_RS03540 nitrogen regulation protein NR(I) 0.24 ABCV34_RS01610 DUF423 domain-containing protein low > 48
Rhodanobacter denitrificans FW104-10B01 0.46 LRK54_RS07980 nitrogen regulation protein NR(I) 0.26 LRK54_RS14520 DUF423 domain-containing protein low > 59
Rhodanobacter denitrificans MT42 0.46 LRK55_RS07730 nitrogen regulation protein NR(I) 0.27 LRK55_RS14235 DUF423 domain-containing protein low > 63
Rhodanobacter sp000427505 FW510-R12 0.45 LRK53_RS00570 nitrogen regulation protein NR(I) 0.33 LRK53_RS14060 DUF423 domain-containing protein low > 59
Rhodanobacter sp. FW510-T8 0.45 OKGIIK_14465 ntrC nitrogen regulation protein NR(I) 0.26 OKGIIK_03370 DUF423 domain-containing protein low > 53
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS15515 nitrogen regulation protein NR(I) 0.31 ABZR86_RS21295 DUF423 domain-containing protein low > 74
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_0137 nitrogen regulation protein NR(I) 0.26 Ga0059261_0742 Uncharacterized small membrane protein low > 68
Sphingobium sp. HT1-2 0.38 GFF1148 Nitrogen regulation protein NR(I), GlnG (=NtrC) 0.24 GFF1285 FIG00018398: hypothetical regulator low > 95
Pontibacter actiniarum KMM 6156, DSM 19842 0.34 CA264_04380 response regulator 0.32 CA264_06425 DUF423 domain-containing protein low > 74
Caulobacter crescentus NA1000 0.33 CCNA_03424 AAA-family response regulator tacA 0.30 CCNA_01289 hypothetical protein low > 66
Caulobacter crescentus NA1000 Δfur 0.33 CCNA_03424 AAA-family response regulator tacA 0.30 CCNA_01289 hypothetical protein low > 67
Cellulophaga baltica 18 0.33 M666_RS19210 sigma-54 dependent transcriptional regulator 0.29 M666_RS03010 DUF423 domain-containing protein low > 67
Brevundimonas sp. GW460-12-10-14-LB2 0.32 A4249_RS09115 sigma-54 dependent transcriptional regulator 0.23 A4249_RS06690 DUF423 domain-containing protein low > 48
Mucilaginibacter yixingensis YX-36 DSM 26809 0.32 ABZR88_RS00090 sigma-54 dependent transcriptional regulator 0.34 ABZR88_RS00705 DUF423 domain-containing protein low > 71
Pedobacter sp. GW460-11-11-14-LB5 0.31 CA265_RS01040 sigma-54-dependent Fis family transcriptional regulator 0.33 CA265_RS10935 DUF423 domain-containing protein low > 88

Not shown: 41 genomes with orthologs for CSW01_13865 only; 2 genomes with orthologs for CSW01_04595 only