Conservation of cofitness between CSW01_02060 and CSW01_01810 in Vibrio cholerae E7946 ATCC 55056

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02060 methionine synthase 1.0 CSW01_01810 tRNA epoxyqueuosine(34) reductase QueG 0.75 8
Klebsiella michiganensis M5al 0.76 BWI76_RS01685 methionine synthase 0.66 BWI76_RS02505 tRNA epoxyqueuosine(34) reductase QueG low > 92
Klebsiella pneumoniae MKP103 0.76 KDGMDA_10165 methionine synthase 0.66 KDGMDA_11005 tRNA epoxyqueuosine(34) reductase QueG low > 95
Pectobacterium carotovorum WPP14 0.76 HER17_RS02310 methionine synthase 0.68 HER17_RS02555 tRNA epoxyqueuosine(34) reductase QueG low > 75
Pantoea agglomerans CFBP13505 P0401 0.76 PagCFBP13505_RS22305 methionine synthase 0.70 PagCFBP13505_RS11155 tRNA epoxyqueuosine(34) reductase QueG low > 74
Escherichia coli BL21 0.76 ECD_03891 homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent 0.67 ECD_04033 epoxyqueuosine reductase, cobalamine-stimulated; queosine biosynthesis low > 61
Escherichia coli BW25113 0.76 b4019 metH B12-dependent methionine synthase (NCBI) 0.67 b4166 yjeS predicted Fe-S electron transport protein (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.76 OHPLBJKB_04030 Methionine synthase 0.67 OHPLBJKB_03876 Epoxyqueuosine reductase low > 74
Escherichia coli ECOR27 0.76 NOLOHH_05380 metH methionine synthase 0.67 NOLOHH_04550 queG tRNA epoxyqueuosine(34) reductase QueG low > 76
Escherichia coli ECRC62 0.76 BNILDI_06140 metH methionine synthase 0.67 BNILDI_06940 queG tRNA epoxyqueuosine(34) reductase QueG low > 75
Dickeya dadantii 3937 0.76 DDA3937_RS19040 methionine synthase 0.69 DDA3937_RS18645 tRNA epoxyqueuosine(34) reductase QueG low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.76 GFF1358 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.67 GFF819 Epoxyqueuosine (oQ) reductase QueG low > 78
Escherichia coli ECOR38 0.76 HEPCGN_11885 metH methionine synthase 0.67 HEPCGN_10515 queG tRNA epoxyqueuosine(34) reductase QueG low > 88
Escherichia coli ECRC101 0.76 MCAODC_03740 metH methionine synthase 0.67 MCAODC_02800 queG tRNA epoxyqueuosine(34) reductase QueG low > 87
Escherichia coli ECRC99 0.76 KEDOAH_14920 metH methionine synthase 0.67 KEDOAH_15870 queG tRNA epoxyqueuosine(34) reductase QueG — —
Escherichia coli ECRC102 0.76 NIAGMN_10990 metH methionine synthase 0.67 NIAGMN_10135 queG tRNA epoxyqueuosine(34) reductase QueG low > 80
Escherichia coli ECRC100 0.76 OKFHMN_13240 metH methionine synthase 0.67 OKFHMN_12285 queG tRNA epoxyqueuosine(34) reductase QueG low > 79
Enterobacter asburiae PDN3 0.76 EX28DRAFT_4326 methionine synthase (B12-dependent) (EC 2.1.1.13) 0.66 EX28DRAFT_3363 epoxyqueuosine reductase low > 76
Serratia liquefaciens MT49 0.75 IAI46_23155 methionine synthase 0.67 IAI46_01595 tRNA epoxyqueuosine(34) reductase QueG low > 87
Escherichia coli ECRC98 0.75 JDDGAC_16865 metH methionine synthase 0.67 JDDGAC_15925 queG tRNA epoxyqueuosine(34) reductase QueG low > 87
Escherichia fergusonii Becca 0.75 EFB2_04592 Methionine synthase 0.67 EFB2_04369 Epoxyqueuosine reductase low > 86
Pantoea sp. MT58 0.75 IAI47_17990 methionine synthase 0.70 IAI47_02560 tRNA epoxyqueuosine(34) reductase QueG low > 76
Escherichia coli Nissle 1917 0.75 ECOLIN_RS23160 methionine synthase 0.67 ECOLIN_RS24200 tRNA epoxyqueuosine(34) reductase QueG low > 55
Rahnella sp. WP5 0.75 EX31_RS11760 methionine synthase 0.66 EX31_RS08850 tRNA epoxyqueuosine(34) reductase QueG low > 89
Dickeya dianthicola ME23 0.75 DZA65_RS20250 methionine synthase 0.68 DZA65_RS19710 tRNA epoxyqueuosine(34) reductase QueG low > 75
Enterobacter sp. TBS_079 0.75 MPMX20_00235 Methionine synthase 0.65 MPMX20_00447 Epoxyqueuosine reductase low > 85
Dickeya dianthicola 67-19 0.75 HGI48_RS19130 methionine synthase 0.68 HGI48_RS18575 tRNA epoxyqueuosine(34) reductase QueG low > 71
Shewanella amazonensis SB2B 0.67 Sama_0758 metH B12-dependent methionine synthase (RefSeq) 0.61 Sama_2625 iron-sulfur cluster-binding protein (RefSeq) low > 62
Shewanella sp. ANA-3 0.66 Shewana3_3282 metH B12-dependent methionine synthase (RefSeq) 0.64 Shewana3_0745 putative iron-sulfur cluster binding protein (RefSeq) low > 73
Pseudomonas stutzeri RCH2 0.66 Psest_2102 5-methyltetrahydrofolate--homocysteine methyltransferase 0.57 Psest_0677 iron-sulfur cluster binding protein, putative low > 67
Kangiella aquimarina DSM 16071 0.66 B158DRAFT_2466 methionine synthase (B12-dependent) (EC 2.1.1.13) 0.48 B158DRAFT_0486 iron-sulfur cluster binding protein, putative low > 40
Pseudomonas aeruginosa PA14 0.66 IKLFDK_08975 methionine synthase 0.55 IKLFDK_28790 tRNA epoxyqueuosine(34) reductase QueG low > 98
Shewanella oneidensis MR-1 0.66 SO1030 metH 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI ptt file) 0.63 SO3861 iron-sulfur cluster-binding protein (NCBI ptt file) low > 76
Pseudomonas aeruginosa MRSN321 0.66 DY961_RS20955 metH;go_function=zinc methionine synthase 0.55 DY961_RS10540 queG;go_function=4 tRNA epoxyqueuosine(34) reductase QueG low > 100
Pseudomonas aeruginosa PUPa3 0.66 DQ20_RS55030 metH;go_function=zinc methionine synthase 0.56 DQ20_RS51515 queG;go_function=4 tRNA epoxyqueuosine(34) reductase QueG low > 101
Pseudomonas putida KT2440 0.65 PP_2375 cobalamin-dependent methionine synthase 0.54 PP_4900 epoxyqueuosine reductase low > 96
Pseudomonas sp. S08-1 0.65 OH686_03335 methionine synthase 0.55 OH686_09500 epoxyqueuosine reductase low > 80
Pseudomonas segetis P6 0.65 ACVTMO_RS12855 metH methionine synthase 0.55 ACVTMO_RS20630 queG tRNA epoxyqueuosine(34) reductase QueG low > 75
Shewanella loihica PV-4 0.65 Shew_0710 metH B12-dependent methionine synthase (RefSeq) 0.64 Shew_2979 putative iron-sulfur cluster binding protein (RefSeq) low > 60
Pseudomonas sp. BP01 0.65 JOY50_RS10720 metH methionine synthase 0.54 JOY50_RS17200 queG tRNA epoxyqueuosine(34) reductase QueG low > 84
Pseudomonas fluorescens SBW25-INTG 0.65 PFLU_RS13000 methionine synthase 0.55 PFLU_RS02540 tRNA epoxyqueuosine(34) reductase QueG low > 109
Pseudomonas fluorescens SBW25 0.65 PFLU_RS13000 methionine synthase 0.55 PFLU_RS02540 tRNA epoxyqueuosine(34) reductase QueG low > 109
Pseudomonas sp. DMC3 0.65 GFF3687 Methionine synthase 0.55 GFF3214 Epoxyqueuosine reductase low > 89
Pseudomonas sp. RS175 0.64 PFR28_01369 Methionine synthase 0.54 PFR28_05115 Epoxyqueuosine reductase low > 88
Pseudomonas sp. SVBP6 0.64 COO64_RS24910 metH methionine synthase 0.54 COO64_RS17870 queG tRNA epoxyqueuosine(34) reductase QueG low > 93
Pseudomonas fluorescens FW300-N2C3 0.64 AO356_00545 methionine synthase 0.54 AO356_08685 epoxyqueuosine reductase low > 104
Pseudomonas fluorescens FW300-N2E2 0.64 Pf6N2E2_2068 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.54 Pf6N2E2_3620 Epoxyqueuosine (oQ) reductase QueG low > 103
Pseudomonas fluorescens GW456-L13 0.64 PfGW456L13_2847 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.54 PfGW456L13_160 Epoxyqueuosine (oQ) reductase QueG low > 87
Pseudomonas simiae WCS417 0.64 PS417_12310 methionine synthase 0.54 PS417_02460 epoxyqueuosine reductase low > 88
Pseudomonas lactucae CFBP13502 0.64 GEMAOFIL_02709 Methionine synthase 0.54 GEMAOFIL_00730 Epoxyqueuosine reductase low > 96
Pseudomonas fluorescens FW300-N2E3 0.64 AO353_21615 methionine synthase 0.54 AO353_13115 epoxyqueuosine reductase low > 101
Pseudomonas syringae pv. syringae B728a ΔmexB 0.64 Psyr_2464 methionine synthase (B12-dependent) 0.56 Psyr_0566 4Fe-4S cluster binding protein low > 86
Pseudomonas syringae pv. syringae B728a 0.64 Psyr_2464 methionine synthase (B12-dependent) 0.56 Psyr_0566 4Fe-4S cluster binding protein low > 86
Pseudomonas fluorescens FW300-N1B4 0.64 Pf1N1B4_5661 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.54 Pf1N1B4_1418 Epoxyqueuosine (oQ) reductase QueG low > 87
Dechlorosoma suillum PS 0.63 Dsui_0779 5-methyltetrahydrofolate--homocysteine methyltransferase 0.47 Dsui_3502 iron-sulfur cluster binding protein, putative — —
Marinobacter adhaerens HP15 0.63 HP15_1792 B12-dependent methionine synthase 0.50 HP15_2505 iron-sulfur cluster binding protein low > 73
Acinetobacter baumannii LAC-4 0.62 RR41_RS08790 methionine synthase 0.46 RR41_RS11805 tRNA epoxyqueuosine(34) reductase QueG low > 55
Acinetobacter radioresistens SK82 0.62 MPMX26_02351 Methionine synthase 0.47 MPMX26_01783 Epoxyqueuosine reductase low > 36
Xanthobacter sp. DMC5 0.61 GFF4146 Methionine synthase 0.32 GFF3718 Epoxyqueuosine reductase — —
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS21740 methionine synthase 0.52 HSERO_RS04220 epoxyqueuosine reductase low > 78
Mucilaginibacter yixingensis YX-36 DSM 26809 0.61 ABZR88_RS20930 methionine synthase 0.30 ABZR88_RS07975 tRNA epoxyqueuosine(34) reductase QueG low > 71
Pontibacter actiniarum KMM 6156, DSM 19842 0.60 CA264_16785 methionine synthase 0.29 CA264_19810 epoxyqueuosine reductase low > 74
Pedobacter sp. GW460-11-11-14-LB5 0.60 CA265_RS23440 methionine synthase 0.33 CA265_RS07695 tRNA epoxyqueuosine(34) reductase QueG low > 88
Sinorhizobium meliloti 1021 0.59 SMc03112 B12-dependent methionine synthase 0.31 SMc00406 4Fe-4S ferredoxin low > 103
Rhizobium sp. OAE497 0.59 ABIE40_RS12135 methionine synthase 0.32 ABIE40_RS01310 tRNA epoxyqueuosine(34) reductase QueG low > 107
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14560 methionine synthase 0.48 ABCV34_RS13905 tRNA epoxyqueuosine(34) reductase QueG low > 48
Methylophilus sp. DMC18 0.57 GFF2281 Methionine synthase 0.52 GFF1249 Epoxyqueuosine reductase low > 43
Parabacteroides merdae CL09T00C40 0.49 HMPREF1078_RS14955 methionine synthase 0.26 HMPREF1078_RS06835 tRNA epoxyqueuosine(34) reductase QueG low > 61
Synechococcus elongatus PCC 7942 0.23 Synpcc7942_1372 metH methionine synthase (B12-dependent) 0.29 Synpcc7942_0530 4Fe-4S cluster binding — —
Magnetospirillum magneticum AMB-1 0.21 AMB_RS02225 methionine synthase 0.32 AMB_RS03995 tRNA epoxyqueuosine(34) reductase QueG — —
Rhodospirillum rubrum S1H 0.21 Rru_A1531 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI) 0.33 Rru_A0279 4Fe-4S ferredoxin, iron-sulfur binding (NCBI) — —

Not shown: 6 genomes with orthologs for CSW01_02060 only; 33 genomes with orthologs for CSW01_01810 only