| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_05825 | | transcriptional regulator HexR | 1.0 | CSW01_01485 | | transcriptional regulator | 0.77 | 19 |
| Serratia liquefaciens MT49 | 0.78 | IAI46_14580 | | MurR/RpiR family transcriptional regulator | 0.54 | IAI46_23965 | | gluconate operon transcriptional repressor GntR | low | > 87 |
| Pectobacterium carotovorum WPP14 | 0.77 | HER17_RS11785 | | MurR/RpiR family transcriptional regulator | 0.52 | HER17_RS01450 | | gluconate operon transcriptional repressor GntR | low | > 75 |
| Rahnella sp. WP5 | 0.76 | EX31_RS10635 | | MurR/RpiR family transcriptional regulator | 0.54 | EX31_RS05060 | | gluconate operon transcriptional repressor GntR | low | > 89 |
| Dickeya dianthicola ME23 | 0.75 | DZA65_RS10575 | | MurR/RpiR family transcriptional regulator | 0.55 | DZA65_RS20970 | | gluconate operon transcriptional repressor GntR | low | > 75 |
| Dickeya dianthicola 67-19 | 0.75 | HGI48_RS10160 | | MurR/RpiR family transcriptional regulator | 0.55 | HGI48_RS19900 | | gluconate operon transcriptional repressor GntR | low | > 71 |
| Dickeya dadantii 3937 | 0.75 | DDA3937_RS10130 | | MurR/RpiR family transcriptional regulator | 0.55 | DDA3937_RS19785 | | gluconate operon transcriptional repressor GntR | low | > 74 |
| Enterobacter asburiae PDN3 | 0.74 | EX28DRAFT_0703 | | transcriptional regulator, RpiR family | 0.51 | EX28DRAFT_4274 | | transcriptional regulator, LacI family | low | > 76 |
| Enterobacter sp. TBS_079 | 0.74 | MPMX20_02758 | | HTH-type transcriptional regulator HexR | 0.52 | MPMX20_04319 | | HTH-type transcriptional regulator GntR | low | > 85 |
| Escherichia coli ECRC98 | 0.73 | JDDGAC_00900 | hexR | DNA-binding transcriptional regulator HexR | 0.52 | JDDGAC_20465 | gntR | gluconate operon transcriptional repressor GntR | low | > 87 |
| Escherichia fergusonii Becca | 0.73 | EFB2_02089 | | HTH-type transcriptional regulator HexR | 0.52 | EFB2_00382 | | HTH-type transcriptional regulator GntR | low | > 86 |
| Escherichia coli ECRC102 | 0.73 | NIAGMN_01735 | hexR | DNA-binding transcriptional regulator HexR | 0.52 | NIAGMN_14605 | gntR | gluconate operon transcriptional repressor GntR | 0.51 | 50 |
| Escherichia coli ECRC101 | 0.73 | MCAODC_19080 | hexR | DNA-binding transcriptional regulator HexR | 0.52 | MCAODC_07365 | gntR | gluconate operon transcriptional repressor GntR | low | > 87 |
| Escherichia coli ECOR38 | 0.73 | HEPCGN_04730 | hexR | DNA-binding transcriptional regulator HexR | 0.52 | HEPCGN_15660 | gntR | gluconate operon transcriptional repressor GntR | low | > 88 |
| Escherichia coli ECRC62 | 0.73 | BNILDI_15635 | hexR | DNA-binding transcriptional regulator HexR | 0.52 | BNILDI_02870 | gntR | gluconate operon transcriptional repressor GntR | low | > 75 |
| Escherichia coli Nissle 1917 | 0.73 | ECOLIN_RS10325 | | DNA-binding transcriptional regulator HexR | 0.52 | ECOLIN_RS19675 | | gluconate operon transcriptional repressor GntR | low | > 55 |
| Escherichia coli ECOR27 | 0.73 | NOLOHH_16840 | hexR | DNA-binding transcriptional regulator HexR | 0.51 | NOLOHH_08635 | gntR | gluconate operon transcriptional repressor GntR | low | > 76 |
| Escherichia coli ECRC99 | 0.73 | KEDOAH_01780 | hexR | DNA-binding transcriptional regulator HexR | 0.52 | KEDOAH_11305 | gntR | gluconate operon transcriptional repressor GntR | — | — |
| Escherichia coli ECRC100 | 0.73 | OKFHMN_26325 | hexR | DNA-binding transcriptional regulator HexR | 0.52 | OKFHMN_16835 | gntR | gluconate operon transcriptional repressor GntR | low | > 79 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.73 | OHPLBJKB_01875 | | HTH-type transcriptional regulator HexR | 0.52 | OHPLBJKB_00264 | | HTH-type transcriptional regulator GntR | low | > 74 |
| Escherichia coli BL21 | 0.73 | ECD_01824 | | putative DNA-binding transcriptional regulator | 0.51 | ECD_03289 | | d-gluconate inducible gluconate regulon transcriptional repressor | low | > 61 |
| Escherichia coli BW25113 | 0.73 | b1853 | yebK | predicted DNA-binding transcriptional regulator (NCBI) | 0.52 | b3438 | gntR | DNA-binding transcriptional repressor (NCBI) | low | > 76 |
| Alteromonas macleodii MIT1002 | 0.73 | MIT1002_02408 | | putative HTH-type transcriptional regulator YbbH | 0.31 | MIT1002_03475 | | Gluconate utilization system GNT-I transcriptional repressor | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.72 | GFF1632 | | Phosphogluconate repressor HexR, RpiR family | 0.49 | GFF570 | | Gluconate utilization system Gnt-I transcriptional repressor | low | > 78 |
| Klebsiella pneumoniae MKP103 | 0.72 | KDGMDA_25375 | | transcriptional regulator HexR | 0.51 | KDGMDA_07120 | | gluconate operon transcriptional repressor GntR | low | > 95 |
| Klebsiella michiganensis M5al | 0.72 | BWI76_RS18110 | | transcriptional regulator HexR | 0.51 | BWI76_RS26245 | | transcriptional regulator | low | > 92 |
| Erwinia tracheiphila HP pepo 2.2 | 0.64 | IJEDHG_22185 | | transcriptional regulator HexR | 0.54 | IJEDHG_08040 | gntR | gluconate operon transcriptional repressor GntR | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.64 | LU632_RS13365 | | MurR/RpiR family transcriptional regulator | 0.53 | LU632_RS19160 | gntR | gluconate operon transcriptional repressor GntR | low | > 73 |
| Pantoea sp. MT58 | 0.63 | IAI47_08490 | | MurR/RpiR family transcriptional regulator | 0.52 | IAI47_01650 | | gluconate operon transcriptional repressor GntR | low | > 76 |
| Pantoea agglomerans CFBP13505 P0401 | 0.61 | PagCFBP13505_RS02370 | | transcriptional regulator HexR | 0.50 | PagCFBP13505_RS18155 | | gluconate operon transcriptional repressor GntR | low | > 74 |
| Pseudomonas sp. SVBP6 | 0.58 | COO64_RS04585 | hexR | DNA-binding transcriptional regulator HexR | 0.34 | COO64_RS25590 | | LacI family DNA-binding transcriptional regulator | low | > 93 |
| Pseudomonas sp. DMC3 | 0.58 | GFF5141 | | HTH-type transcriptional regulator HexR | 0.33 | GFF5268 | | HTH-type transcriptional regulator GntR | low | > 89 |
| Pseudomonas sp. RS175 | 0.57 | PFR28_00572 | | HTH-type transcriptional regulator HexR | 0.34 | PFR28_00593 | | HTH-type transcriptional regulator GntR | low | > 88 |
| Pseudomonas fluorescens FW300-N2E2 | 0.57 | Pf6N2E2_2886 | | Phosphogluconate repressor HexR, RpiR family | 0.34 | Pf6N2E2_2865 | | Gluconate utilization system Gnt-I transcriptional repressor | low | > 103 |
| Pseudomonas fluorescens GW456-L13 | 0.57 | PfGW456L13_1900 | | Phosphogluconate repressor HexR, RpiR family | 0.34 | PfGW456L13_1925 | | Gluconate utilization system Gnt-I transcriptional repressor | low | > 87 |
| Pseudomonas fluorescens FW300-N2C3 | 0.57 | AO356_05165 | | transcriptional regulator | 0.34 | AO356_05065 | | LacI family transcriptional regulator | low | > 104 |
| Pseudomonas fluorescens FW300-N1B4 | 0.57 | Pf1N1B4_590 | | Phosphogluconate repressor HexR, RpiR family | 0.35 | Pf1N1B4_558 | | Gluconate utilization system Gnt-I transcriptional repressor | low | > 87 |
| Pseudomonas stutzeri RCH2 | 0.57 | Psest_0851 | | Transcriptional regulators | 0.34 | Psest_2126 | | Transcriptional regulators | low | > 67 |
| Pseudomonas fluorescens FW300-N2E3 | 0.57 | AO353_03365 | | transcriptional regulator | 0.33 | AO353_03255 | | LacI family transcriptional regulator | low | > 101 |
| Pseudomonas orientalis W4I3 | 0.57 | QF045_RS24250 | | MurR/RpiR family transcriptional regulator | 0.34 | QF045_RS24095 | | LacI family DNA-binding transcriptional regulator | low | > 93 |
| Pseudomonas putida KT2440 | 0.57 | PP_1021 | | DNA-binding transcriptional regulator | 0.31 | PP_3415 | | Transcriptional regulator, LacI family | 0.40 | 1 |
| Pseudomonas segetis P6 | 0.57 | MPMX49_02832 | | HTH-type transcriptional regulator HexR | 0.33 | MPMX49_02373 | | HTH-type transcriptional regulator GntR | low | > 75 |
| Pseudomonas simiae WCS417 | 0.57 | PS417_22115 | | transcriptional regulator | 0.33 | PS417_21990 | | LacI family transcriptional regulator | low | > 88 |
| Pseudomonas lactucae CFBP13502 | 0.57 | GEMAOFIL_04559 | | HTH-type transcriptional regulator HexR | 0.34 | GEMAOFIL_04536 | | HTH-type transcriptional regulator GntR | low | > 96 |
| Pseudomonas fluorescens SBW25 | 0.57 | PFLU_RS23730 | | MurR/RpiR family transcriptional regulator | 0.34 | PFLU_RS23595 | | LacI family DNA-binding transcriptional regulator | 0.55 | 27 |
| Pseudomonas sp. BP01 | 0.57 | JOY50_RS11445 | hexR | DNA-binding transcriptional regulator HexR | 0.31 | JOY50_RS23605 | | LacI family DNA-binding transcriptional regulator | low | > 84 |
| Pseudomonas fluorescens SBW25-INTG | 0.57 | PFLU_RS23730 | | MurR/RpiR family transcriptional regulator | 0.34 | PFLU_RS23595 | | LacI family DNA-binding transcriptional regulator | 0.40 | 6 |
| Pseudomonas syringae pv. syringae B728a | 0.56 | Psyr_1119 | | Helix-turn-helix protein RpiR:Sugar isomerase (SIS) | 0.32 | Psyr_3336 | | transcriptional regulator, LacI family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.56 | Psyr_1119 | | Helix-turn-helix protein RpiR:Sugar isomerase (SIS) | 0.32 | Psyr_3336 | | transcriptional regulator, LacI family | low | > 86 |
| Pseudomonas aeruginosa PA14 | 0.55 | IKLFDK_16180 | | HTH-type transcriptional regulator HexR | 0.36 | IKLFDK_11375 | | LacI family DNA-binding transcriptional regulator GntR | low | > 98 |
| Pseudomonas aeruginosa MRSN321 | 0.55 | DY961_RS01015 | | MurR/RpiR family transcriptional regulator | 0.36 | DY961_RS17990 | gntR;inference=COORDINATES | LacI family DNA-binding transcriptional regulator GntR | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.55 | DQ20_RS34520 | | MurR/RpiR family transcriptional regulator | 0.36 | DQ20_RS59230 | gntR;inference=COORDINATES | LacI family DNA-binding transcriptional regulator GntR | low | > 101 |
| Castellaniella sp019104865 MT123 | 0.39 | ABCV34_RS08655 | | SIS domain-containing protein | 0.26 | ABCV34_RS12285 | | LacI family DNA-binding transcriptional regulator | low | > 48 |
| Sinorhizobium meliloti 1021 | 0.38 | SMc02460 | | hypothetical protein | 0.29 | SM_b20667 | | LacI family transcriptional regulator | low | > 103 |
| Azospirillum brasilense Sp245 | 0.35 | AZOBR_RS30190 | | transcriptional regulator | 0.31 | AZOBR_RS15720 | | LacI family transcription regulator | — | — |
| Burkholderia phytofirmans PsJN | 0.34 | BPHYT_RS16740 | | transcriptional regulator | 0.32 | BPHYT_RS00410 | | LacI family transcription regulator | low | > 109 |
| Acidovorax sp. GW101-3H11 | 0.34 | Ac3H11_2055 | | Probable transcriptional regulator | 0.29 | Ac3H11_3230 | | Gluconate utilization system Gnt-I transcriptional repressor | low | > 79 |
| Cupriavidus basilensis FW507-4G11 | 0.34 | RR42_RS06120 | | transcriptional regulator | 0.26 | RR42_RS22645 | | GntR family transcriptional regulator | low | > 128 |
| Azospirillum sp. SherDot2 | 0.33 | MPMX19_05117 | | HTH-type transcriptional regulator HexR | 0.29 | MPMX19_05332 | | HTH-type transcriptional regulator GntR | low | > 112 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.33 | H281DRAFT_04279 | | transcriptional regulator, RpiR family | 0.30 | H281DRAFT_05920 | | transcriptional regulator, LacI family | low | > 103 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.33 | GFF1364 | | Phosphogluconate repressor HexR, RpiR family | 0.30 | GFF5509 | | Gluconate utilization system Gnt-I transcriptional repressor | low | > 90 |
| Herbaspirillum seropedicae SmR1 | 0.32 | HSERO_RS05505 | | transcriptional regulator | 0.34 | HSERO_RS05460 | | LacI family transcription regulator | low | > 78 |
| Paraburkholderia sabiae LMG 24235 | 0.30 | QEN71_RS26925 | | MurR/RpiR family transcriptional regulator | 0.29 | QEN71_RS13585 | | LacI family DNA-binding transcriptional regulator | low | > 153 |
| Rhizobium sp. OAE497 | 0.25 | ABIE40_RS21410 | | MurR/RpiR family transcriptional regulator | 0.25 | ABIE40_RS04445 | | LacI family DNA-binding transcriptional regulator | low | > 107 |
| Agrobacterium fabrum C58 | 0.25 | Atu2598 | | transcriptional regulator, RpiR family | 0.28 | Atu4685 | | LacI family transcriptional regulator | low | > 89 |
| Ralstonia solanacearum GMI1000 | 0.23 | RS_RS22855 | | MurR/RpiR family transcriptional regulator | 0.26 | RS_RS24865 | | LacI family DNA-binding transcriptional regulator | low | > 80 |
| Ralstonia sp. UNC404CL21Col | 0.22 | ABZR87_RS03145 | | MurR/RpiR family transcriptional regulator | 0.26 | ABZR87_RS18255 | | LacI family DNA-binding transcriptional regulator | low | > 80 |
| Ralstonia solanacearum IBSBF1503 | 0.22 | RALBFv3_RS18180 | | MurR/RpiR family transcriptional regulator | 0.24 | RALBFv3_RS16125 | | GntR family transcriptional regulator | low | > 76 |
| Ralstonia solanacearum PSI07 | 0.22 | RPSI07_RS05455 | | MurR/RpiR family transcriptional regulator | 0.26 | RPSI07_RS07575 | | LacI family DNA-binding transcriptional regulator | low | > 81 |
| Ralstonia solanacearum UW163 | 0.22 | UW163_RS20950 | | MurR/RpiR family transcriptional regulator | 0.24 | UW163_RS16860 | | GntR family transcriptional regulator | — | — |
| Variovorax sp. OAS795 | 0.20 | ABID97_RS22860 | | MurR/RpiR family transcriptional regulator | 0.29 | ABID97_RS01205 | | LacI family DNA-binding transcriptional regulator | low | > 91 |
| Variovorax sp. SCN45 | 0.20 | GFF6715 | | Transcriptional regulator of RpiR family in catabolic operon | 0.30 | GFF7257 | | KEGG: LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor | low | > 127 |
| Phaeobacter inhibens DSM 17395 | 0.10 | PGA1_c27130 | | putative HTH-type transcriptional regulator | 0.28 | PGA1_c33870 | | putative HTH-type transcriptional regulator GntR | low | > 62 |
Not shown: 7 genomes with orthologs for CSW01_05825 only; 3 genomes with orthologs for CSW01_01485 only