Conservation of cofitness between CSW01_01380 and CSW01_01420 in Vibrio cholerae E7946 ATCC 55056

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_01380 D-2-hydroxyacid dehydrogenase 1.0 CSW01_01420 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase 0.70 15
Shewanella sp. ANA-3 0.40 Shewana3_0583 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.77 Shewana3_0441 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 73
Shewanella amazonensis SB2B 0.39 Sama_3039 Phosphoglycerate dehydrogenase (EC 1.1.1.95) (from data) 0.78 Sama_0395 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 62
Shewanella loihica PV-4 0.39 Shew_0553 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (RefSeq) 0.79 Shew_3412 purH bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.38 SO0585 D-isomer specific 2-hydroxyacid dehydrogenase family protein (NCBI ptt file) 0.76 SO0442 purH phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.29 MIT1002_03160 Glyoxylate/hydroxypyruvate reductase A 0.77 MIT1002_03959 Bifunctional purine biosynthesis protein PurH — —
Pectobacterium carotovorum WPP14 0.27 HER17_RS02495 D-2-hydroxyacid dehydrogenase 0.78 HER17_RS20335 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Pseudomonas fluorescens GW456-L13 0.26 PfGW456L13_4494 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.69 PfGW456L13_57 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Pseudomonas fluorescens FW300-N2E3 0.26 AO353_17865 hydroxyacid dehydrogenase 0.68 AO353_13650 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas simiae WCS417 0.26 PS417_07385 2-hydroxyacid dehydrogenase 0.69 PS417_02940 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas sp. SVBP6 0.26 COO64_RS26160 D-2-hydroxyacid dehydrogenase 0.69 COO64_RS18305 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 93
Pseudomonas fluorescens SBW25 0.26 PFLU_RS07475 D-2-hydroxyacid dehydrogenase 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH low > 109
Pseudomonas fluorescens SBW25-INTG 0.26 PFLU_RS07475 D-2-hydroxyacid dehydrogenase 0.69 PFLU_RS03015 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas sp. BP01 0.26 JOY50_RS01545 D-2-hydroxyacid dehydrogenase 0.69 JOY50_RS17625 purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas lactucae CFBP13502 0.25 GEMAOFIL_01611 Glyoxylate/hydroxypyruvate reductase A 0.69 GEMAOFIL_00820 Bifunctional purine biosynthesis protein PurH — —
Pseudomonas orientalis W4I3 0.25 QF045_RS10040 D-2-hydroxyacid dehydrogenase 0.69 QF045_RS05975 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 93
Pseudomonas sp. DMC3 0.25 GFF2313 Glyoxylate/hydroxypyruvate reductase A 0.69 GFF3308 Bifunctional purine biosynthesis protein PurH low > 89
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_3347 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.69 Pf1N1B4_1315 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.25 Psyr_1565 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein 0.67 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.25 Psyr_1565 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein 0.67 Psyr_4406 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Dickeya dadantii 3937 0.25 DDA3937_RS18695 D-2-hydroxyacid dehydrogenase 0.79 DDA3937_RS01220 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 74
Pseudomonas fluorescens FW300-N2E2 0.25 Pf6N2E2_2725 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.68 Pf6N2E2_3519 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Dickeya dianthicola 67-19 0.25 HGI48_RS18625 D-2-hydroxyacid dehydrogenase 0.79 HGI48_RS01215 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 71
Pseudomonas putida KT2440 0.25 PP_4589 D-isomer specific 2-hydroxyacid dehydrogenase family protein 0.69 PP_4822 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas sp. RS175 0.25 PFR28_00714 Glyoxylate/hydroxypyruvate reductase A 0.69 PFR28_05214 Bifunctional purine biosynthesis protein PurH — —
Dickeya dianthicola ME23 0.24 DZA65_RS19760 D-2-hydroxyacid dehydrogenase 0.79 DZA65_RS01260 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 75
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_04410 hydroxyacid dehydrogenase 0.68 AO356_08225 phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Pseudomonas segetis P6 0.24 MPMX49_01840 Glyoxylate/hydroxypyruvate reductase A 0.69 MPMX49_04108 Bifunctional purine biosynthesis protein PurH — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.24 CA264_03335 glyoxylate/hydroxypyruvate reductase A 0.33 CA264_18630 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase low > 74
Pseudomonas aeruginosa PA14 0.24 IKLFDK_06150 D-2-hydroxyacid dehydrogenase 0.67 IKLFDK_29290 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 98
Pseudomonas aeruginosa MRSN321 0.24 DY961_RS18815 D-2-hydroxyacid dehydrogenase 0.67 DY961_RS10050 purH;go_function=catalytic bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 100
Pseudomonas sp. S08-1 0.24 OH686_05305 D-3-phosphoglycerate dehydrogenase 0.71 OH686_07620 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Pseudomonas aeruginosa PUPa3 0.24 DQ20_RS52955 D-2-hydroxyacid dehydrogenase 0.67 DQ20_RS52005 purH;go_function=catalytic bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Paraburkholderia sabiae LMG 24235 0.23 QEN71_RS32025 glyoxylate/hydroxypyruvate reductase A 0.59 QEN71_RS26780 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 153
Paraburkholderia graminis OAS925 0.21 ABIE53_005027 glyoxylate/hydroxypyruvate reductase A 0.60 ABIE53_003491 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.21 Echvi_3471 Phosphoglycerate dehydrogenase and related dehydrogenases 0.33 Echvi_1469 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) — —
Acinetobacter radioresistens SK82 0.20 MPMX26_01500 Glyoxylate/hydroxypyruvate reductase A 0.67 MPMX26_01141 Bifunctional purine biosynthesis protein PurH — —
Serratia liquefaciens MT49 0.20 IAI46_09955 glyoxylate/hydroxypyruvate reductase GhrA 0.80 IAI46_01365 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 87
Bifidobacterium breve UCC2003 0.20 BBR_RS17310 D-2-hydroxyacid dehydrogenase 0.35 BBR_RS15690 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Pseudomonas stutzeri RCH2 0.20 Psest_2788 Phosphoglycerate dehydrogenase and related dehydrogenases 0.68 Psest_1014 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Lysobacter sp. OAE881 0.20 ABIE51_RS10035 glyoxylate/hydroxypyruvate reductase A 0.56 ABIE51_RS17760 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 62
Paraburkholderia bryophila 376MFSha3.1 0.20 H281DRAFT_06341 glyoxylate/hydroxypyruvate reductase A 0.59 H281DRAFT_04251 IMP cyclohydrolase /phosphoribosylaminoimidazolecarboxamide formyltransferase — —
Klebsiella michiganensis M5al 0.20 BWI76_RS21910 glyoxylate/hydroxypyruvate reductase A 0.80 BWI76_RS01615 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase low > 92
Variovorax sp. OAS795 0.20 ABID97_RS25925 glyoxylate/hydroxypyruvate reductase A 0.55 ABID97_RS24725 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Azospirillum sp. SherDot2 0.19 MPMX19_00078 Glyoxylate/hydroxypyruvate reductase A 0.50 MPMX19_02325 Bifunctional purine biosynthesis protein PurH — —
Ralstonia solanacearum UW163 0.19 UW163_RS20235 glyoxylate/hydroxypyruvate reductase A 0.58 UW163_RS01900 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Herbaspirillum seropedicae SmR1 0.19 HSERO_RS05655 D-2-hydroxyacid dehydrogenase 0.57 HSERO_RS02060 purine biosynthesis protein purH — —
Ralstonia solanacearum IBSBF1503 0.19 RALBFv3_RS18895 glyoxylate/hydroxypyruvate reductase A 0.58 RALBFv3_RS11685 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Ralstonia solanacearum PSI07 0.19 RPSI07_RS04655 glyoxylate/hydroxypyruvate reductase A 0.58 RPSI07_RS21530 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH — —
Enterobacter sp. TBS_079 0.19 MPMX20_01715 Glyoxylate/hydroxypyruvate reductase A 0.79 MPMX20_00226 Bifunctional purine biosynthesis protein PurH low > 85
Klebsiella pneumoniae MKP103 0.19 KDGMDA_18520 glyoxylate/hydroxypyruvate reductase GhrA 0.80 KDGMDA_10100 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 95
Ralstonia sp. UNC404CL21Col 0.18 ABZR87_RS21550 glyoxylate/hydroxypyruvate reductase A 0.58 ABZR87_RS07640 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Variovorax sp. SCN45 0.18 GFF2017 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) 0.56 GFF2146 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) — —
Azospirillum brasilense Sp245 0.18 AZOBR_RS03790 D-2-hydroxyacid dehydrogenase 0.49 AZOBR_RS00225 purine biosynthesis protein purH — —
Castellaniella sp019104865 MT123 0.18 ABCV34_RS06730 glyoxylate/hydroxypyruvate reductase A 0.56 ABCV34_RS07970 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Agrobacterium fabrum C58 0.17 Atu5474 2-hydroxyacid dehydrogenase 0.45 Atu2823 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase — —
Phaeobacter inhibens DSM 17395 0.17 PGA1_c26570 putative glyoxylate/hydroxypyruvate reductase A 0.50 PGA1_c32860 bifunctional purine biosynthesis protein PurH — —
Sinorhizobium meliloti 1021 0.17 SMc02828 hydroxyacid dehydrogenase 0.45 SMc04088 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 103
Pantoea agglomerans CFBP13505 P0401 0.17 PagCFBP13505_RS01525 glyoxylate/hydroxypyruvate reductase A 0.80 PagCFBP13505_RS22575 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 74
Dinoroseobacter shibae DFL-12 0.16 Dshi_0590 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding (RefSeq) 0.49 Dshi_0358 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (RefSeq) — —
Rhizobium sp. OAE497 0.16 ABIE40_RS00635 glyoxylate/hydroxypyruvate reductase A 0.46 ABIE40_RS19130 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase low > 107

Not shown: 0 genomes with orthologs for CSW01_01380 only; 59 genomes with orthologs for CSW01_01420 only