Conservation of cofitness between BWI76_RS17800 and BWI76_RS24105 in Klebsiella michiganensis M5al

62 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS17800 long-chain-fatty-acid--CoA ligase 1.0 BWI76_RS24105 resistance protein 0.33 3
Enterobacter sp. TBS_079 0.96 MPMX20_02711 Long-chain-fatty-acid--CoA ligase 0.91 MPMX20_03810 hypothetical protein low > 85
Enterobacter asburiae PDN3 0.95 EX28DRAFT_0753 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II 0.91 EX28DRAFT_2990 Predicted integral membrane protein low > 76
Escherichia coli ECOR27 0.94 NOLOHH_17115 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 NOLOHH_11120 yggT osmotic shock tolerance protein YggT low > 75
Escherichia coli ECRC62 0.94 BNILDI_15900 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 BNILDI_09700 yggT osmotic shock tolerance protein YggT low > 75
Escherichia coli ECOR38 0.94 HEPCGN_04985 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 HEPCGN_18555 yggT osmotic shock tolerance protein YggT low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.94 OHPLBJKB_01928 Long-chain-fatty-acid--CoA ligase 0.90 OHPLBJKB_00764 hypothetical protein 0.37 36
Escherichia fergusonii Becca 0.94 EFB2_02195 Long-chain-fatty-acid--CoA ligase 0.90 EFB2_00950 hypothetical protein low > 86
Escherichia coli ECRC102 0.94 NIAGMN_01470 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 NIAGMN_17015 yggT osmotic shock tolerance protein YggT — —
Escherichia coli ECRC101 0.94 MCAODC_18815 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 MCAODC_09770 yggT osmotic shock tolerance protein YggT low > 87
Escherichia coli ECRC100 0.94 OKFHMN_26595 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 OKFHMN_19250 yggT osmotic shock tolerance protein YggT low > 80
Escherichia coli ECRC98 0.94 JDDGAC_01170 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 JDDGAC_22880 yggT osmotic shock tolerance protein YggT low > 86
Escherichia coli ECRC99 0.94 KEDOAH_01515 fadD long-chain-fatty-acid--CoA ligase FadD 0.90 KEDOAH_08890 yggT osmotic shock tolerance protein YggT — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2820 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) 0.85 GFF3055 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) low > 78
Escherichia coli BW25113 0.93 b1805 fadD acyl-CoA synthase (NCBI) 0.90 b2952 yggT predicted inner membrane protein (NCBI) low > 76
Escherichia coli Nissle 1917 0.93 ECOLIN_RS10040 long-chain-fatty-acid--CoA ligase FadD 0.90 ECOLIN_RS16420 osmotic shock tolerance protein YggT — —
Escherichia coli BL21 0.93 ECD_01775 acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase) 0.90 ECD_02782 putative inner membrane protein; compensates for loss in K+ uptake — —
Serratia liquefaciens MT49 0.79 IAI46_14535 long-chain-fatty-acid--CoA ligase FadD 0.54 IAI46_21420 YggT family protein low > 86
Rahnella sp. WP5 0.79 EX31_RS10600 long-chain-fatty-acid--CoA ligase FadD 0.59 EX31_RS02695 YggT family protein low > 89
Pantoea sp. MT58 0.77 IAI47_08835 long-chain-fatty-acid--CoA ligase FadD 0.58 IAI47_03590 YggT family protein low > 76
Pectobacterium carotovorum WPP14 0.76 HER17_RS11275 long-chain-fatty-acid--CoA ligase FadD 0.59 HER17_RS03800 YggT family protein low > 75
Dickeya dianthicola 67-19 0.75 HGI48_RS11260 long-chain-fatty-acid--CoA ligase FadD 0.54 HGI48_RS17355 YggT family protein 0.49 40
Dickeya dianthicola ME23 0.74 DZA65_RS11605 long-chain-fatty-acid--CoA ligase FadD 0.54 DZA65_RS18445 YggT family protein low > 75
Vibrio cholerae E7946 ATCC 55056 0.70 CSW01_09905 long-chain-fatty-acid--CoA ligase FadD 0.53 CSW01_02445 hypothetical protein low > 62
Shewanella sp. ANA-3 0.68 Shewana3_2386 long-chain-fatty-acid--CoA ligase (RefSeq) 0.42 Shewana3_1192 protein of unknown function YGGT (RefSeq) low > 73
Shewanella amazonensis SB2B 0.68 Sama_1934 long-chain-fatty-acid--CoA ligase (RefSeq) 0.43 Sama_2479 protein of unknown function YGGT (RefSeq) — —
Shewanella loihica PV-4 0.66 Shew_2188 long-chain-fatty-acid--CoA ligase (RefSeq) 0.48 Shew_1135 protein of unknown function YGGT (RefSeq) — —
Shewanella oneidensis MR-1 0.66 SO2581 fadD-1 long-chain-fatty-acid--CoA ligase (NCBI ptt file) 0.44 SO3355 conserved hypothetical protein (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.61 MIT1002_02588 Long-chain-fatty-acid--CoA ligase 0.45 MIT1002_03063 YGGT family protein low > 70
Kangiella aquimarina DSM 16071 0.59 B158DRAFT_1573 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II 0.26 B158DRAFT_0198 Predicted integral membrane protein low > 40
Rhodanobacter sp. FW510-T8 0.59 OKGIIK_06445 menE,fadK long-chain-fatty-acid--CoA ligase 0.19 OKGIIK_11140 YGGT family low > 52
Dechlorosoma suillum PS 0.58 Dsui_3212 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II 0.24 Dsui_0601 putative integral membrane protein — —
Dyella japonica UNC79MFTsu3.2 0.58 ABZR86_RS02155 AMP-binding protein 0.17 ABZR86_RS10430 YggT family protein low > 74
Cupriavidus basilensis FW507-4G11 0.56 RR42_RS18150 long-chain fatty acid--CoA ligase 0.31 RR42_RS36110 membrane protein low > 128
Castellaniella sp019104865 MT123 0.55 ABCV34_RS11410 AMP-binding protein 0.27 ABCV34_RS10650 YggT family protein — —
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS19285 long-chain fatty acid--CoA ligase 0.19 HSERO_RS01900 hypothetical protein — —
Pseudomonas putida KT2440 0.55 PP_4549 long-chain-fatty-acid/CoA ligase 0.30 PP_5096 putative factor involved in shape determination low > 96
Burkholderia phytofirmans PsJN 0.55 BPHYT_RS17295 long-chain fatty acid--CoA ligase 0.27 BPHYT_RS15440 membrane protein — —
Ralstonia solanacearum UW163 0.55 UW163_RS07285 long-chain-fatty-acid--CoA ligase 0.21 UW163_RS21640 YggT family protein — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS06340 long-chain-fatty-acid--CoA ligase 0.21 RALBFv3_RS17510 YggT family protein low > 76
Paraburkholderia bryophila 376MFSha3.1 0.55 H281DRAFT_06226 long-chain acyl-CoA synthetase 0.30 H281DRAFT_04033 YggT family protein low > 103
Ralstonia sp. UNC404CL21Col 0.55 ABZR87_RS02020 long-chain fatty acid--CoA ligase 0.29 ABZR87_RS18295 YggT family protein low > 80
Marinobacter adhaerens HP15 0.55 HP15_1864 acyl-CoA synthase 0.33 HP15_286 protein of unknown function YGGT 0.36 14
Ralstonia solanacearum PSI07 0.55 RPSI07_RS10900 long-chain-fatty-acid--CoA ligase 0.27 RPSI07_RS06140 YggT family protein low > 81
Ralstonia solanacearum GMI1000 0.55 RS_RS14290 long-chain-fatty-acid--CoA ligase 0.28 RS_RS23805 YggT family protein low > 80
Paraburkholderia graminis OAS925 0.55 ABIE53_003625 long-chain acyl-CoA synthetase 0.29 ABIE53_003258 YggT family protein 0.27 25
Paraburkholderia sabiae LMG 24235 0.55 QEN71_RS22975 AMP-binding protein 0.30 QEN71_RS03230 YggT family protein low > 153
Pseudomonas syringae pv. syringae B728a ΔmexB 0.54 Psyr_3834 AMP-dependent synthetase and ligase 0.30 Psyr_0475 Protein of unknown function YGGT low > 86
Pseudomonas syringae pv. syringae B728a 0.54 Psyr_3834 AMP-dependent synthetase and ligase 0.30 Psyr_0475 Protein of unknown function YGGT low > 86
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_2872 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) 0.29 Pf6N2E2_4599 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) low > 103
Pseudomonas sp. RS175 0.54 PFR28_00585 Long-chain-fatty-acid--CoA ligase 0.29 PFR28_04244 hypothetical protein low > 88
Pseudomonas simiae WCS417 0.54 PS417_22065 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) (from data) 0.29 PS417_26735 membrane protein — —
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_1911 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) 0.28 PfGW456L13_1009 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) low > 87
Acidovorax sp. GW101-3H11 0.54 Ac3H11_663 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) 0.27 Ac3H11_1537 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.54 GFF2607 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) 0.17 GFF4919 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) — —
Pseudomonas stutzeri RCH2 0.54 Psest_1334 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II 0.34 Psest_0282 Predicted integral membrane protein — —
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_05100 long-chain fatty acid--CoA ligase 0.29 AO356_13415 hypothetical protein low > 104
Pseudomonas fluorescens SBW25 0.54 PFLU_RS23680 long-chain fatty acid--CoA ligase 0.29 PFLU_RS28380 YggT family protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS23680 long-chain fatty acid--CoA ligase 0.29 PFLU_RS28380 YggT family protein low > 109
Pseudomonas sp. S08-1 0.54 OH686_05750 Long-chain-fatty-acid--CoA ligase 0.32 OH686_10985 YggT-like protein low > 80
Variovorax sp. OAS795 0.52 ABID97_RS04445 long-chain-fatty-acid--CoA ligase 0.23 ABID97_RS08415 YggT family protein low > 91
Variovorax sp. SCN45 0.52 GFF7283 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) 0.23 GFF3880 Cell division integral membrane protein, YggT and half-length relatives low > 127
Acinetobacter radioresistens SK82 0.50 MPMX26_00141 Long-chain-fatty-acid--CoA ligase 0.18 MPMX26_00573 hypothetical protein low > 36

Not shown: 35 genomes with orthologs for BWI76_RS17800 only; 2 genomes with orthologs for BWI76_RS24105 only