Conservation of cofitness between Atu3298 and Atu4017 in Agrobacterium fabrum C58

71 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu3298 C4-dicarboxylate transporter DctA 1.0 Atu4017 MFS permease 0.33 11
Castellaniella sp019104865 MT123 0.73 ABCV34_RS02715 dicarboxylate/amino acid:cation symporter 0.41 ABCV34_RS09940 MFS transporter low > 48
Xanthomonas campestris pv. campestris strain 8004 0.70 Xcc-8004.1034.1 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate, aspartate 0.42 Xcc-8004.5310.1 dicarboxylate transport protein low > 74
Sphingobium sp. HT1-2 0.69 GFF161 Na+/H+-dicarboxylate symporter 0.71 GFF5307 FIG00883918: hypothetical protein low > 95
Brevundimonas sp. GW460-12-10-14-LB2 0.68 A4249_RS04425 dicarboxylate/amino acid:cation symporter 0.63 A4249_RS02835 MFS transporter low > 48
Acinetobacter baumannii LAC-4 0.68 RR41_RS06660 dicarboxylate/amino acid:cation symporter 0.74 RR41_RS04240 MFS transporter low > 55
Sphingomonas koreensis DSMZ 15582 0.64 Ga0059261_0617 Na+/H+-dicarboxylate symporters 0.70 Ga0059261_3091 Sugar (and other) transporter
Escherichia coli ECOR27 0.61 NOLOHH_08160 dctA C4-dicarboxylate transporter DctC 0.47 NOLOHH_12970 kgtP alpha-ketoglutarate permease low > 76
Escherichia coli ECRC62 0.61 BNILDI_03395 dctA C4-dicarboxylate transporter DctC 0.47 BNILDI_11775 kgtP alpha-ketoglutarate permease low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.61 OHPLBJKB_00174 Aerobic C4-dicarboxylate transport protein 0.47 OHPLBJKB_01119 Alpha-ketoglutarate permease low > 74
Escherichia coli Nissle 1917 0.61 ECOLIN_RS20180 C4-dicarboxylate transporter DctC 0.48 ECOLIN_RS14640 alpha-ketoglutarate permease low > 55
Escherichia coli ECOR38 0.61 HEPCGN_15100 dctA C4-dicarboxylate transporter DctC 0.47 HEPCGN_20425 kgtP alpha-ketoglutarate permease low > 88
Escherichia coli BW25113 0.61 b3528 dctA C4 dicarboxylate/orotate:H+ symporter (DctA) (from data) 0.47 b2587 kgtP alpha-ketoglutarate transporter (NCBI) 0.37 7
Escherichia fergusonii Becca 0.61 EFB2_00280 Aerobic C4-dicarboxylate transport protein 0.48 EFB2_01309 Alpha-ketoglutarate permease low > 86
Escherichia coli BL21 0.61 ECD_03376 C4-dicarboxylic acid, orotate and citrate transporter 0.47 ECD_02481 alpha-ketoglutarate transporter low > 61
Escherichia coli ECRC100 0.61 OKFHMN_16195 dctA C4-dicarboxylate transporter DctC 0.48 OKFHMN_21300 kgtP alpha-ketoglutarate permease 0.58 27
Escherichia coli ECRC102 0.61 NIAGMN_13960 dctA C4-dicarboxylate transporter DctC 0.48 NIAGMN_19070 kgtP alpha-ketoglutarate permease low > 80
Escherichia coli ECRC99 0.61 KEDOAH_11955 dctA C4-dicarboxylate transporter DctC 0.48 KEDOAH_06920 kgtP alpha-ketoglutarate permease
Rahnella sp. WP5 0.61 EX31_RS05445 dicarboxylate/amino acid:cation symporter 0.47 EX31_RS13690 MFS transporter low > 89
Pseudomonas lactucae CFBP13502 0.61 GEMAOFIL_04444 C4-dicarboxylate transport protein 2 0.62 GEMAOFIL_04683 Alpha-ketoglutarate permease low > 93
Escherichia coli ECRC101 0.61 MCAODC_06710 dctA C4-dicarboxylate transporter DctC 0.48 MCAODC_11830 kgtP alpha-ketoglutarate permease low > 88
Escherichia coli ECRC98 0.61 JDDGAC_19825 dctA C4-dicarboxylate transporter DctC 0.48 JDDGAC_24965 kgtP alpha-ketoglutarate permease low > 87
Pseudomonas fluorescens SBW25 0.61 PFLU_RS23115 dicarboxylate/amino acid:cation symporter 0.62 PFLU_RS24285 MFS transporter 0.42 34
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS23115 dicarboxylate/amino acid:cation symporter 0.62 PFLU_RS24285 MFS transporter low > 109
Pseudomonas syringae pv. syringae B728a 0.60 Psyr_3707 Sodium:dicarboxylate symporter 0.62 Psyr_3999 General substrate transporter:Major facilitator superfamily 0.25 57
Pseudomonas syringae pv. syringae B728a ΔmexB 0.60 Psyr_3707 Sodium:dicarboxylate symporter 0.62 Psyr_3999 General substrate transporter:Major facilitator superfamily low > 86
Pseudomonas simiae WCS417 0.60 PS417_21500 C4 dicarboxylate transporter DctA (from data) 0.62 PS417_22650 MFS transporter low > 88
Pseudomonas sp. DMC3 0.60 GFF4837 C4-dicarboxylate transport protein 2 0.60 GFF5042 Alpha-ketoglutarate permease low > 89
Pseudomonas aeruginosa PA14 0.60 IKLFDK_05485 C4-dicarboxylate transporter DctC 0.63 IKLFDK_25760 alpha-ketoglutarate permease low > 100
Ralstonia solanacearum GMI1000 0.60 RS_RS01625 C4-dicarboxylate transporter 1 0.57 RS_RS17230 MFS transporter low > 80
Ralstonia solanacearum PSI07 0.60 RPSI07_RS22530 dicarboxylate/amino acid:cation symporter 0.58 RPSI07_RS00035 MFS transporter low > 81
Acinetobacter radioresistens SK82 0.59 MPMX26_02024 C4-dicarboxylate transport protein 2 0.36 MPMX26_01705 Alpha-ketoglutarate permease low > 36
Pseudomonas fluorescens FW300-N1B4 0.59 Pf1N1B4_3487 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate, aspartate 0.61 Pf1N1B4_686 Dicarboxylate MFS transporter low > 87
Pseudomonas putida KT2440 0.59 PP_1188 C4-dicarboxylate transport protein 0.61 PP_1400 Alpha-ketoglutarate permease low > 96
Ralstonia solanacearum IBSBF1503 0.59 RALBFv3_RS10785 dicarboxylate/amino acid:cation symporter 0.58 RALBFv3_RS23235 MFS transporter 0.59 52
Ralstonia solanacearum UW163 0.59 UW163_RS02795 dicarboxylate/amino acid:cation symporter 0.58 UW163_RS16485 MFS transporter
Dickeya dianthicola ME23 0.59 DZA65_RS21850 dicarboxylate/amino acid:cation symporter 0.47 DZA65_RS17945 MFS transporter low > 75
Dickeya dianthicola 67-19 0.59 HGI48_RS20835 dicarboxylate/amino acid:cation symporter 0.47 HGI48_RS16870 MFS transporter low > 71
Serratia liquefaciens MT49 0.59 IAI46_00550 dicarboxylate/amino acid:cation symporter 0.48 IAI46_20040 MFS transporter low > 86
Klebsiella michiganensis M5al 0.59 BWI76_RS26760 C4-dicarboxylate transport protein DctA (from data) 0.46 BWI76_RS21415 MFS transporter low > 92
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_5707 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate 0.61 Pf6N2E2_5486 Alpha-ketoglutarate permease (from data) low > 103
Ralstonia sp. UNC404CL21Col 0.59 ABZR87_RS06625 dicarboxylate/amino acid:cation symporter 0.59 ABZR87_RS16295 MFS transporter low > 80
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_2016 C4-dicarboxylate transporter (from data) 0.60 PfGW456L13_1805 Dicarboxylate MFS transporter low > 87
Pseudomonas sp. BP01 0.59 JOY50_RS01965 dicarboxylate/amino acid:cation symporter 0.61 JOY50_RS14525 MFS transporter 0.33 31
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_18980 sodium:C4-dicarboxylate symporter (dctA) (from data) 0.61 AO356_17790 alpha-ketoglutarate permease (MHS family) (from data) low > 104
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS01365 dicarboxylate/amino acid:cation symporter 0.48 QEN71_RS07390 MFS family transporter 0.58 8
Pseudomonas sp. SVBP6 0.59 COO64_RS07410 dicarboxylate/amino acid:cation symporter 0.62 COO64_RS26190 MFS transporter low > 93
Pseudomonas sp. RS175 0.59 PFR28_03241 C4-dicarboxylate transport protein 2 0.61 PFR28_03468 Alpha-ketoglutarate permease low > 88
Paraburkholderia graminis OAS925 0.59 ABIE53_000646 aerobic C4-dicarboxylate transport protein 0.49 ABIE53_002314 MHS family alpha-ketoglutarate permease-like MFS transporter 0.26 7
Enterobacter sp. TBS_079 0.59 MPMX20_04413 Aerobic C4-dicarboxylate transport protein 0.49 MPMX20_03456 Alpha-ketoglutarate permease low > 85
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_02039 aerobic C4-dicarboxylate transport protein 0.46 H281DRAFT_05236 MFS transporter, MHS family, alpha-ketoglutarate permease low > 103
Pantoea agglomerans CFBP13505 P0401 0.59 PagCFBP13505_RS15580 dicarboxylate/amino acid:cation symporter 0.50 PagCFBP13505_RS14455 MFS transporter low > 74
Burkholderia phytofirmans PsJN 0.59 BPHYT_RS02510 C4-dicarboxylate ABC transporter 0.46 BPHYT_RS11175 alpha-ketoglutarate transporter low > 109
Cupriavidus basilensis FW507-4G11 0.58 RR42_RS01695 C4-dicarboxylate transporter 0.47 RR42_RS21430 alpha-ketoglutarate permease low > 128
Enterobacter asburiae PDN3 0.58 EX28DRAFT_4049 Na+/H+-dicarboxylate symporters 0.49 EX28DRAFT_0060 metabolite-proton symporter low > 76
Klebsiella pneumoniae MKP103 0.58 KDGMDA_07500 C4-dicarboxylate transport protein 0.46 KDGMDA_28540 alpha-ketoglutarate transporter low > 95
Variovorax sp. OAS795 0.58 ABID97_RS26560 dicarboxylate/amino acid:cation symporter 0.48 ABID97_RS08005 MFS family transporter
Pectobacterium carotovorum WPP14 0.58 HER17_RS00400 dicarboxylate/amino acid:cation symporter 0.49 HER17_RS04420 MFS transporter low > 75
Pantoea sp. MT58 0.58 IAI47_18585 dicarboxylate/amino acid:cation symporter 0.49 IAI47_04465 MFS transporter low > 76
Erwinia amylovora T8 0.57 OLJFJH_04805 C4-dicarboxylate transport protein 0.48 OLJFJH_09770 alpha-ketoglutarate transporter low > 58
Dickeya dadantii 3937 0.57 DDA3937_RS00555 dicarboxylate/amino acid:cation symporter 0.47 DDA3937_RS16800 MFS transporter low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.57 GFF495 Aerobic C4-dicarboxylate transporter for fumarate, L-malate, D-malate, succunate 0.50 GFF2093 Alpha-ketoglutarate permease low > 78
Herbaspirillum seropedicae SmR1 0.57 HSERO_RS13105 C4-dicarboxylate ABC transporter 0.46 HSERO_RS16820 2-oxoglutarate:H+ symporter (from data) low > 78
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_02800 C4-dicarboxylate transporter 0.62 AO353_03810 Alpha-ketoglutarate permease, MFS superfamily (from data) low > 101
Variovorax sp. SCN45 0.57 GFF1694 Na+/H+-dicarboxylate symporter 0.49 GFF5985 dicarboxylic acid transporter PcaT low > 127
Dyella japonica UNC79MFTsu3.2 0.56 ABZR86_RS08515 dicarboxylate/amino acid:cation symporter 0.59 ABZR86_RS08525 MFS transporter low > 74
Caulobacter crescentus NA1000 Δfur 0.56 CCNA_00664 C4-dicarboxylate transport protein 0.55 CCNA_01071 alpha-ketoglutarate permease low > 67
Caulobacter crescentus NA1000 0.56 CCNA_00664 C4-dicarboxylate transport protein 0.55 CCNA_01071 alpha-ketoglutarate permease low > 66
Pedobacter sp. GW460-11-11-14-LB5 0.47 CA265_RS15560 glutamate/aspartate:proton symporter GltP 0.58 CA265_RS22390 alpha-ketoglutarate transporter low > 88
Mucilaginibacter yixingensis YX-36 DSM 26809 0.45 ABZR88_RS20325 C4-dicarboxylate transporter DctA 0.57 ABZR88_RS05955 MFS transporter low > 71
Mycobacterium tuberculosis H37Rv 0.35 Rv2443 Probable C4-dicarboxylate-transport transmembrane protein DctA 0.43 Rv3476c Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) low > 58
Pseudomonas segetis P6 0.25 MPMX49_00162 Proton/glutamate-aspartate symporter 0.22 MPMX49_00464 Proline/betaine transporter low > 75

Not shown: 29 genomes with orthologs for Atu3298 only; 3 genomes with orthologs for Atu4017 only