Conservation of cofitness between b4015 and b1853 in Escherichia coli BW25113

62 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b4015 aceA isocitrate lyase (NCBI) 1.0 b1853 yebK predicted DNA-binding transcriptional regulator (NCBI) 0.21 13
Escherichia coli ECOR27 1.00 NOLOHH_05410 aceA isocitrate lyase 1.00 NOLOHH_16840 hexR DNA-binding transcriptional regulator HexR low > 57
Escherichia coli BL21 1.00 ECD_03887 isocitrate lyase 1.00 ECD_01824 putative DNA-binding transcriptional regulator low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04035 Isocitrate lyase 1.00 OHPLBJKB_01875 HTH-type transcriptional regulator HexR low > 73
Escherichia coli Nissle 1917 1.00 ECOLIN_RS26870 isocitrate lyase 0.99 ECOLIN_RS10325 DNA-binding transcriptional regulator HexR
Escherichia coli ECOR38 1.00 HEPCGN_11905 aceA isocitrate lyase 1.00 HEPCGN_04730 hexR DNA-binding transcriptional regulator HexR low > 85
Escherichia coli ECRC62 1.00 BNILDI_06110 aceA isocitrate lyase 1.00 BNILDI_15635 hexR DNA-binding transcriptional regulator HexR
Escherichia fergusonii Becca 1.00 EFB2_04595 Isocitrate lyase 0.99 EFB2_02089 HTH-type transcriptional regulator HexR low > 86
Escherichia coli ECRC99 1.00 KEDOAH_14895 aceA isocitrate lyase 1.00 KEDOAH_01780 hexR DNA-binding transcriptional regulator HexR
Escherichia coli ECRC98 1.00 JDDGAC_16890 aceA isocitrate lyase 1.00 JDDGAC_00900 hexR DNA-binding transcriptional regulator HexR
Escherichia coli ECRC101 1.00 OKFHMN_13265 aceA isocitrate lyase 1.00 OKFHMN_26325 hexR DNA-binding transcriptional regulator HexR
Escherichia coli ECRC101 1.00 MCAODC_03765 aceA isocitrate lyase 1.00 MCAODC_19080 hexR DNA-binding transcriptional regulator HexR
Escherichia coli ECRC102 1.00 NIAGMN_11015 aceA isocitrate lyase 1.00 NIAGMN_01735 hexR DNA-binding transcriptional regulator HexR
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.97 GFF1352 Isocitrate lyase (EC 4.1.3.1) 0.93 GFF1632 Phosphogluconate repressor HexR, RpiR family low > 78
Klebsiella michiganensis M5al 0.96 BWI76_RS01665 Isocitrate lyase (EC 4.1.3.1) (from data) 0.90 BWI76_RS18110 transcriptional regulator HexR low > 92
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4329 isocitrate lyase 0.91 EX28DRAFT_0703 transcriptional regulator, RpiR family low > 76
Enterobacter sp. TBS_079 0.94 MPMX20_00232 Isocitrate lyase 0.90 MPMX20_02758 HTH-type transcriptional regulator HexR 0.28 13
Pectobacterium carotovorum WPP14 0.89 HER17_RS02295 isocitrate lyase 0.83 HER17_RS11785 MurR/RpiR family transcriptional regulator low > 75
Dickeya dianthicola 67-19 0.89 HGI48_RS19145 isocitrate lyase 0.80 HGI48_RS10160 MurR/RpiR family transcriptional regulator low > 71
Dickeya dadantii 3937 0.88 DDA3937_RS19055 isocitrate lyase 0.81 DDA3937_RS10130 MurR/RpiR family transcriptional regulator low > 74
Dickeya dianthicola ME23 0.88 DZA65_RS20265 isocitrate lyase 0.80 DZA65_RS10575 MurR/RpiR family transcriptional regulator low > 75
Rahnella sp. WP5 0.87 EX31_RS11745 isocitrate lyase 0.82 EX31_RS10635 MurR/RpiR family transcriptional regulator low > 89
Serratia liquefaciens MT49 0.87 IAI46_23190 isocitrate lyase 0.83 IAI46_14580 MurR/RpiR family transcriptional regulator low > 86
Pantoea sp. MT58 0.84 IAI47_18005 isocitrate lyase 0.67 IAI47_08490 MurR/RpiR family transcriptional regulator low > 76
Shewanella loihica PV-4 0.83 Shew_1276 Isocitrate lyase (EC 4.1.3.1) (from data) 0.74 Shew_2049 DNA-binding transcriptional regulator HexR (RefSeq) low > 60
Shewanella amazonensis SB2B 0.83 Sama_2380 Isocitrate lyase (EC 4.1.3.1) (from data) 0.74 Sama_1813 DNA-binding transcriptional regulator HexR (RefSeq) 0.39 46
Shewanella oneidensis MR-1 0.82 SO1484 aceA Isocitrate lyase (EC 4.1.3.1) (from data) 0.74 SO2490 transcriptional regulator, RpiR family (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.82 Shewana3_2942 isocitrate lyase (RefSeq) 0.74 Shewana3_2152 DNA-binding transcriptional regulator HexR (RefSeq) 0.31 59
Vibrio cholerae E7946 ATCC 55056 0.80 CSW01_03830 isocitrate lyase 0.72 CSW01_05825 transcriptional regulator HexR low > 62
Variovorax sp. OAS795 0.75 ABID97_RS11115 isocitrate lyase 0.24 ABID97_RS22860 MurR/RpiR family transcriptional regulator low > 91
Pseudomonas fluorescens SBW25-INTG 0.74 PFLU_RS18610 isocitrate lyase 0.54 PFLU_RS23730 MurR/RpiR family transcriptional regulator low > 109
Pseudomonas fluorescens SBW25 0.74 PFLU_RS18610 isocitrate lyase 0.54 PFLU_RS23730 MurR/RpiR family transcriptional regulator low > 109
Variovorax sp. SCN45 0.74 GFF4829 Isocitrate lyase (EC 4.1.3.1) 0.23 GFF6715 Transcriptional regulator of RpiR family in catabolic operon low > 127
Pseudomonas simiae WCS417 0.74 PS417_16570 isocitrate lyase 0.54 PS417_22115 transcriptional regulator low > 88
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_27735 isocitrate lyase 0.55 AO353_03365 transcriptional regulator low > 101
Hydrogenophaga sp. GW460-11-11-14-LB1 0.74 GFF4147 Isocitrate lyase (EC 4.1.3.1) 0.34 GFF1364 Phosphogluconate repressor HexR, RpiR family low > 90
Pseudomonas fluorescens GW456-L13 0.74 PfGW456L13_2633 Isocitrate lyase (EC 4.1.3.1) 0.55 PfGW456L13_1900 Phosphogluconate repressor HexR, RpiR family low > 87
Pseudomonas fluorescens FW300-N1B4 0.74 Pf1N1B4_4042 Isocitrate lyase (EC 4.1.3.1) (from data) 0.56 Pf1N1B4_590 Phosphogluconate repressor HexR, RpiR family low > 87
Pseudomonas syringae pv. syringae B728a 0.74 Psyr_3196 isocitrate lyase 0.55 Psyr_1119 Helix-turn-helix protein RpiR:Sugar isomerase (SIS) 0.40 32
Pseudomonas sp. RS175 0.74 PFR28_02625 Isocitrate lyase 0.55 PFR28_00572 HTH-type transcriptional regulator HexR 0.23 66
Pseudomonas syringae pv. syringae B728a ΔmexB 0.74 Psyr_3196 isocitrate lyase 0.55 Psyr_1119 Helix-turn-helix protein RpiR:Sugar isomerase (SIS) low > 86
Pseudomonas fluorescens FW300-N2C3 0.74 AO356_22080 isocitrate lyase 0.56 AO356_05165 transcriptional regulator 0.40 28
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_279 Isocitrate lyase (EC 4.1.3.1) 0.56 Pf6N2E2_2886 Phosphogluconate repressor HexR, RpiR family 0.32 35
Acidovorax sp. GW101-3H11 0.73 Ac3H11_2831 Isocitrate lyase (EC 4.1.3.1) (from data) 0.35 Ac3H11_2055 Probable transcriptional regulator low > 79
Pseudomonas putida KT2440 0.73 PP_4116 isocitrate lyase 0.55 PP_1021 DNA-binding transcriptional regulator low > 96
Castellaniella sp019104865 MT123 0.71 ABCV34_RS06915 isocitrate lyase 0.40 ABCV34_RS08655 SIS domain-containing protein low > 48
Paraburkholderia graminis OAS925 0.69 ABIE53_002536 isocitrate lyase 0.35 ABIE53_003518 RpiR family carbohydrate utilization transcriptional regulator low > 113
Paraburkholderia bryophila 376MFSha3.1 0.69 H281DRAFT_00580 isocitrate lyase 0.35 H281DRAFT_04279 transcriptional regulator, RpiR family low > 103
Paraburkholderia sabiae LMG 24235 0.69 QEN71_RS06270 isocitrate lyase 0.33 QEN71_RS26925 MurR/RpiR family transcriptional regulator low > 153
Herbaspirillum seropedicae SmR1 0.69 HSERO_RS10565 isocitrate lyase 0.36 HSERO_RS05505 transcriptional regulator low > 78
Cupriavidus basilensis FW507-4G11 0.68 RR42_RS12200 isocitrate lyase 0.34 RR42_RS06120 transcriptional regulator low > 128
Burkholderia phytofirmans PsJN 0.68 BPHYT_RS12285 isocitrate lyase 0.35 BPHYT_RS16740 transcriptional regulator low > 109
Ralstonia solanacearum UW163 0.67 UW163_RS13480 isocitrate lyase 0.22 UW163_RS17145 MurR/RpiR family transcriptional regulator
Ralstonia solanacearum IBSBF1503 0.67 RALBFv3_RS00150 isocitrate lyase 0.22 RALBFv3_RS16405 MurR/RpiR family transcriptional regulator low > 76
Ralstonia solanacearum PSI07 0.67 RPSI07_RS17335 isocitrate lyase 0.22 RPSI07_RS07300 MurR/RpiR family transcriptional regulator low > 81
Ralstonia solanacearum GMI1000 0.66 RS_RS06810 isocitrate lyase 0.23 RS_RS24600 MurR/RpiR family transcriptional regulator low > 80
Ralstonia sp. UNC404CL21Col 0.66 ABZR87_RS11590 isocitrate lyase 0.23 ABZR87_RS03145 MurR/RpiR family transcriptional regulator low > 80
Azospirillum sp. SherDot2 0.59 MPMX19_05830 Isocitrate lyase 0.34 MPMX19_04844 HTH-type transcriptional regulator HexR low > 112
Sinorhizobium meliloti 1021 0.57 SMc00768 isocitrate lyase 0.36 SMc02460 hypothetical protein 0.36 68
Rhizobium sp. OAE497 0.57 ABIE40_RS03255 isocitrate lyase 0.27 ABIE40_RS21410 MurR/RpiR family transcriptional regulator low > 107
Agrobacterium fabrum C58 0.57 Atu0607 isocitrate lyase 0.22 Atu2598 transcriptional regulator, RpiR family low > 89
Azospirillum brasilense Sp245 0.56 AZOBR_RS02405 isocitrate lyase 0.38 AZOBR_RS30190 transcriptional regulator low > 97
Alteromonas macleodii MIT1002 0.16 MIT1002_02831 Isocitrate lyase 0.70 MIT1002_02408 putative HTH-type transcriptional regulator YbbH

Not shown: 15 genomes with orthologs for b4015 only; 4 genomes with orthologs for b1853 only