| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Methanococcus maripaludis S2 | MMP_RS08110 | | tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 | no data | 100 | 100 |
| o | Methanococcus maripaludis JJ | MMJJ_RS06255 | | tRNA uridine(34) 5-carboxymethylaminomethyl modification radical SAM/GNAT enzyme Elp3 | strong | 98 | 100 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1562 | | Radical SAM domain protein (RefSeq) | no data | 27 | 38 |
| | Fusobacterium nucleatum SB010 | HUW76_02255 | | radical SAM protein | cofit | 25 | 47 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0394 | | radical SAM domain protein (TIGR) | no data | 30 | 37 |
| | Methanococcus maripaludis S2 | MMP_RS07685 | | TIGR01212 family radical SAM protein | strong | 28 | 28 |
| | Methanococcus maripaludis JJ | MMJJ_RS06675 | | TIGR01212 family radical SAM protein | strong | 27 | 28 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0790 | | radical SAM protein, TIGR01212 family (TIGR) | insig. | 27 | 27 |
| | Shewanella loihica PV-4 | Shew_1033 | | putative radical SAM protein (RefSeq) | insig. | 29 | 31 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS18470 | | TIGR01212 family radical SAM protein | insig. | 28 | 30 |
| | Escherichia fergusonii Becca | EFB2_00612 | | hypothetical protein | insig. | 28 | 30 |
| | Escherichia coli ECOR38 | HEPCGN_16765 | yhcC | TIGR01212 family radical SAM protein | insig. | 28 | 30 |
| | Escherichia coli BL21 | ECD_03076 | | putative Fe-S oxidoreductase, Radical SAM superfamily protein | insig. | 28 | 30 |
| | Escherichia coli ECOR27 | NOLOHH_09690 | yhcC | TIGR01212 family radical SAM protein | insig. | 28 | 30 |
| | Escherichia coli ECRC100 | OKFHMN_17890 | yhcC | TIGR01212 family radical SAM protein | cofit | 28 | 30 |
| | Escherichia coli ECRC101 | MCAODC_08410 | yhcC | TIGR01212 family radical SAM protein | insig. | 28 | 30 |
| | Escherichia coli ECRC102 | NIAGMN_15650 | yhcC | TIGR01212 family radical SAM protein | insig. | 28 | 30 |
| | Escherichia coli ECRC62 | BNILDI_01845 | yhcC | TIGR01212 family radical SAM protein | insig. | 28 | 30 |
| | Escherichia coli ECRC98 | JDDGAC_21515 | yhcC | TIGR01212 family radical SAM protein | insig. | 28 | 30 |
| | Escherichia coli ECRC99 | KEDOAH_10260 | yhcC | TIGR01212 family radical SAM protein | no data | 28 | 30 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00489 | | hypothetical protein | insig. | 28 | 30 |
| | Escherichia coli BW25113 | b3211 | yhcC | predicted Fe-S oxidoreductase (NCBI) | insig. | 28 | 30 |
| | Shewanella oneidensis MR-1 | SO1326 | | conserved hypothetical protein (NCBI ptt file) | insig. | 32 | 24 |
| | Enterobacter sp. TBS_079 | MPMX20_04125 | | hypothetical protein | insig. | 30 | 25 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0628 | | putative oxygen-independent coproporphyrinogen III oxidase | sig. | 32 | 24 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2819 | | conserved hypothetical radical SAM protein (RefSeq) | insig. | 29 | 25 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2955 | | COG1242: Predicted Fe-S oxidoreductase | insig. | 30 | 23 |
| | Klebsiella michiganensis M5al | BWI76_RS25305 | | TIGR01212 family radical SAM protein | insig. | 32 | 23 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3274 | | radical SAM protein, TIGR01212 family | insig. | 28 | 25 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS11035 | | radical SAM family heme chaperone HemW | cofit | 24 | 39 |
| | Dickeya dianthicola 67-19 | HGI48_RS01565 | | TIGR01212 family radical SAM protein | insig. | 31 | 25 |
| | Dickeya dianthicola ME23 | DZA65_RS01640 | | TIGR01212 family radical SAM protein | insig. | 31 | 25 |
| | Serratia liquefaciens MT49 | IAI46_22340 | | TIGR01212 family radical SAM protein | insig. | 29 | 24 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_06140 | | TIGR01212 family radical SAM protein | insig. | 29 | 26 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS06440 | | radical SAM family heme chaperone HemW | cofit | 27 | 34 |
| | Dickeya dadantii 3937 | DDA3937_RS01670 | | TIGR01212 family radical SAM protein | insig. | 32 | 23 |
| | Fusobacterium nucleatum SB010 | HUW76_06060 | | TIGR01212 family radical SAM protein | cofit | 31 | 26 |
| | Pectobacterium carotovorum WPP14 | HER17_RS19905 | | TIGR01212 family radical SAM protein | cofit | 29 | 25 |
| | Shewanella sp. ANA-3 | Shewana3_3048 | | putative radical SAM protein (RefSeq) | insig. | 29 | 25 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_12015 | | TIGR01212 family radical SAM protein | insig. | 28 | 25 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS14980 | | TIGR01212 family radical SAM protein | insig. | 27 | 34 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS04765 | | TIGR01212 family radical SAM protein | insig. | 27 | 30 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS03545 | | radical SAM family heme chaperone HemW | insig. | 28 | 32 |
| | Agrobacterium fabrum C58 | Atu0325 | | oxygen-independent coproporphyrinogen III oxidase | no data | 28 | 23 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2168 | | coproporphyrinogen III oxidase (NCBI ptt file) | sig. | 27 | 28 |
| | Sinorhizobium meliloti 1021 | SMc01147 | | coproporphyrinogen III oxidase | strong | 27 | 24 |
| | Sphingobium sp. HT1-2 | GFF2622 | | Oxygen-independent coproporphyrinogen-III oxidase-like protein YggW | cofit | 22 | 28 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS07680 | | radical SAM family heme chaperone HemW | sig. | 29 | 21 |
| | Fusobacterium nucleatum SB010 | HUW76_07285 | | radical SAM family heme chaperone HemW | cofit | 28 | 25 |
| | Rhizobium sp. OAE497 | ABIE40_RS01625 | | radical SAM family heme chaperone HemW | no data | 26 | 24 |
| | Cellulophaga baltica 18 | M666_RS07265 | | radical SAM family heme chaperone HemW | insig. | 30 | 24 |
| | Shewanella amazonensis SB2B | Sama_0858 | | hypothetical protein (RefSeq) | insig. | 27 | 25 |
| | Marinobacter adhaerens HP15 | HP15_280 | | putative oxygen-independent coproporphyrinogen III oxidase | insig. | 23 | 41 |
| | Methylophilus sp. DMC18 | GFF1090 | | Oxygen-independent coproporphyrinogen III oxidase | insig. | 28 | 20 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_02425 | | YggW family oxidoreductase | insig. | 27 | 21 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2753 | | putative oxygen-independent coproporphyrinogen III oxidase | insig. | 23 | 26 |
| | Rhodopseudomonas palustris CGA009 | TX73_008565 | | oxygen-independent coproporphyrinogen III oxidase | no data | 26 | 31 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_03177 | | putative oxygen-independent coproporphyrinogen III oxidase | insig. | 22 | 26 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS10115 | | TIGR01212 family radical SAM protein | insig. | 36 | 18 |
| | Bifidobacterium breve UCC2003 | BBR_RS15235 | | coproporphyrinogen III oxidase | insig. | 28 | 24 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_16765 | | coproporphyrinogen III oxidase | sig. | 24 | 23 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS00100 | | radical SAM family heme chaperone HemW | cofit | 28 | 21 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS14495 | | TIGR01212 family radical SAM protein | sig. | 36 | 18 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2374 | | oxygen-independent coproporphyrinogen III oxidase (RefSeq) | insig. | 25 | 22 |
| | Pseudomonas sp. DMC3 | GFF216 | | Heme chaperone HemW | insig. | 26 | 21 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_0201 | | coproporphyrinogen III oxidase, anaerobic (EC 1.3.99.22) | cofit | 25 | 21 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1003 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | sig. | 26 | 21 |
| | Methanococcus maripaludis S2 | MMP_RS06965 | | TIGR04014 family B12-binding domain/radical SAM domain-containing protein | strong | 35 | 13 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS28405 | | radical SAM family heme chaperone HemW | insig. | 25 | 21 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS28405 | | radical SAM family heme chaperone HemW | insig. | 25 | 21 |
| | Rhodospirillum rubrum S1H | Rru_A3639 | | Putative oxygen-independent coproporphyrinogen III oxidase (NCBI) | insig. | 26 | 22 |
| | Rhodopseudomonas palustris CGA009 | TX73_001700 | | radical SAM family heme chaperone HemW | no data | 25 | 23 |
| | Shewanella sp. ANA-3 | Shewana3_1188 | | putative oxygen-independent coproporphyrinogen III oxidase (RefSeq) | insig. | 21 | 42 |
| | Acinetobacter radioresistens SK82 | MPMX26_00308 | | Heme chaperone HemW | cofit | 26 | 21 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS18155 | | coproporphyrinogen III oxidase | sig. | 26 | 24 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_05489 | | Heme chaperone HemW | cofit | 25 | 21 |
| | Methanococcus maripaludis S2 | MMP_RS00285 | | TIGR04013 family B12-binding domain/radical SAM domain-containing protein | insig. | 32 | 19 |
| | Acinetobacter baumannii LAC-4 | RR41_RS17015 | | radical SAM family heme chaperone HemW | insig. | 27 | 21 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS12445 | | radical SAM family heme chaperone HemW | insig. | 23 | 25 |
| | Methanococcus maripaludis JJ | MMJJ_RS07390 | | TIGR04014 family B12-binding domain/radical SAM domain-containing protein | sig. | 34 | 13 |
| | Shewanella amazonensis SB2B | Sama_2483 | | oxygen-independent coproporphyrinogen III oxidase, putative (RefSeq) | insig. | 21 | 41 |
| | Fusobacterium nucleatum SB010 | HUW76_03495 | | B12-binding domain-containing radical SAM protein | strong | 28 | 26 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_08200 | | coproporphyrinogen III oxidase | strong | 25 | 21 |
| | Pseudomonas sp. SVBP6 | COO64_RS12965 | hemW | radical SAM family heme chaperone HemW | insig. | 24 | 21 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08775 | | TIGR01212 family radical SAM protein | insig. | 35 | 14 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_04040 | | oxygen-independent coproporphyrinogen-3 oxidase | sig. | 25 | 24 |
| | Methanococcus maripaludis JJ | MMJJ_RS05200 | | TIGR04013 family B12-binding domain/radical SAM domain-containing protein | insig. | 31 | 19 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS01495 | | Fe-S osidoreductase | insig. | 23 | 20 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2334 | | Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB | insig. | 23 | 21 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04934 | | radical SAM protein, TIGR01212 family | insig. | 35 | 14 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS01360 | | oxygen-independent coproporphyrinogen III oxidase | insig. | 25 | 24 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS13395 | | oxygen-independent coproporphyrinogen III oxidase | insig. | 25 | 24 |