| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Shewanella amazonensis SB2B | Sama_2267 | | response regulator receiver protein (RefSeq) | strong | 100 | 100 |
| o | Shewanella oneidensis MR-1 | SO3196 | | response regulator (NCBI ptt file) | strong | 67 | 100 |
| o | Shewanella sp. ANA-3 | Shewana3_1372 | | response regulator receiver protein (RefSeq) | strong | 66 | 100 |
| o | Shewanella loihica PV-4 | Shew_1396 | | response regulator receiver protein (RefSeq) | insig. | 66 | 100 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_1912 | | Response regulator receiver:Stage II sporulation E | no data | 29 | 78 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_1912 | | Response regulator receiver:Stage II sporulation E | no data | 29 | 78 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01676 | | Regulator of RpoS | no data | 31 | 78 |
| | Pseudomonas orientalis W4I3 | QF045_RS10365 | | SpoIIE family protein phosphatase | no data | 31 | 78 |
| | Pseudomonas sp. SVBP6 | COO64_RS09545 | rssB | two-component system response regulator RssB | no data | 30 | 78 |
| | Pseudomonas simiae WCS417 | PS417_07720 | | chemotaxis protein CheY | no data | 31 | 78 |
| | Pseudomonas putida KT2440 | PP_2165 | | Response regulator | no data | 31 | 78 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_00320 | | chemotaxis protein CheY | no data | 31 | 78 |
| | Pseudomonas sp. BP01 | JOY50_RS25185 | rssB | two-component system response regulator RssB | no data | 31 | 78 |
| | Pseudomonas sp. S08-1 | OH686_22730 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 30 | 76 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4011 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 30 | 78 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 31 | 78 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS07795 | | SpoIIE family protein phosphatase | no data | 31 | 78 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_60 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 31 | 78 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_02185 | | chemotaxis protein CheY | no data | 31 | 78 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2260 | | Serine phosphatase RsbU, regulator of sigma subunit | no data | 31 | 78 |
| | Pseudomonas sp. DMC3 | GFF1302 | | Regulator of RpoS | no data | 30 | 78 |
| | Pseudomonas sp. RS175 | PFR28_01140 | | Regulator of RpoS | no data | 30 | 78 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS03060 | | SpoIIE family protein phosphatase | no data | 29 | 76 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS32530 | rssB;go_process=phosphorelay | two-component system response regulator RssB | no data | 29 | 76 |
| o | Pseudomonas stutzeri RCH2 | Psest_2710 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | no data | 28 | 88 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_14160 | | fused response regulator/phosphatase | no data | 29 | 76 |
| | Pseudomonas segetis P6 | ACVTMO_RS09490 | rssB | two-component system response regulator RssB | no data | 30 | 69 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_05345 | | two-component system response regulator | insig. | 29 | 62 |
| | Rahnella sp. WP5 | EX31_RS10100 | | two-component system response regulator RssB | insig. | 28 | 71 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0408 | | response regulator/sensory box/GGDEF domain/EAL domain protein (TIGR) | sig. | 35 | 43 |
| | Dickeya dianthicola 67-19 | HGI48_RS10350 | | two-component system response regulator RssB | cofit | 29 | 53 |
| | Dickeya dianthicola ME23 | DZA65_RS10825 | | two-component system response regulator RssB | sig. | 29 | 53 |
| | Erwinia amylovora T8 | OLJFJH_13285 | | two-component system response regulator RssB | strong | 32 | 56 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_0064 | | histidine kinase (RefSeq) | sig. | 41 | 32 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_22690 | rssB | two-component system response regulator RssB | strong | 27 | 71 |
| | Erwinia tracheiphila SCR3 | LU632_RS12925 | rssB | two-component system response regulator RssB | cofit | 27 | 71 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1544 | | response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) (RefSeq) | insig. | 32 | 47 |
| | Pectobacterium carotovorum WPP14 | HER17_RS11050 | | two-component system response regulator RssB | cofit | 29 | 54 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2753 | | Hnr protein | strong | 35 | 47 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_3074 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | cofit | 37 | 41 |
| | Serratia liquefaciens MT49 | IAI46_14250 | | two-component system response regulator RssB | cofit | 29 | 54 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1181 | | response regulator (TIGR) | cofit | 36 | 38 |
| | Escherichia coli ECOR27 | NOLOHH_20465 | rssB | two-component system response regulator RssB | insig. | 34 | 47 |
| | Klebsiella michiganensis M5al | BWI76_RS17275 | | two-component system response regulator RssB | insig. | 33 | 47 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1419 | | signal transduction histidine kinase (RefSeq) | cofit | 31 | 43 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_24505 | | two-component system response regulator RssB | sig. | 34 | 47 |
| | Enterobacter sp. TBS_079 | MPMX20_02593 | | Regulator of RpoS | strong | 34 | 53 |
| | Escherichia fergusonii Becca | EFB2_02691 | | Regulator of RpoS | sig. | 34 | 47 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS07475 | | two-component system response regulator RssB | no data | 34 | 47 |
| | Escherichia coli BL21 | ECD_01211 | | PcnB-degradosome interaction factor; response regulator | insig. | 34 | 47 |
| | Escherichia coli ECOR38 | HEPCGN_25045 | rssB | two-component system response regulator RssB | strong | 34 | 47 |
| | Escherichia coli ECRC100 | OKFHMN_28585 | rssB | two-component system response regulator RssB | cofit | 34 | 47 |
| | Escherichia coli ECRC101 | MCAODC_21675 | rssB | two-component system response regulator RssB | strong | 34 | 47 |
| | Escherichia coli ECRC102 | NIAGMN_27650 | rssB | two-component system response regulator RssB | no data | 34 | 47 |
| | Escherichia coli ECRC62 | BNILDI_18620 | rssB | two-component system response regulator RssB | strong | 34 | 47 |
| | Escherichia coli ECRC98 | JDDGAC_05990 | rssB | two-component system response regulator RssB | sig. | 34 | 47 |
| | Escherichia coli ECRC99 | KEDOAH_25580 | rssB | two-component system response regulator RssB | no data | 34 | 47 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_02450 | | Regulator of RpoS | strong | 34 | 47 |
| | Escherichia coli BW25113 | b1235 | rssB | response regulator of RpoS (NCBI) | strong | 34 | 47 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0888 | | response regulator (TIGR) | sig. | 32 | 43 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS02865 | | two-component system response regulator RssB | no data | 27 | 56 |
| | Pantoea sp. MT58 | IAI47_09025 | | two-component system response regulator RssB | no data | 27 | 56 |
| | Cellulophaga baltica 18 | M666_RS19210 | | sigma-54 dependent transcriptional regulator | insig. | 35 | 31 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_0861 | | Response regulator receiver domain | strong | 32 | 53 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS20270 | | chemotaxis response regulator CheY | insig. | 34 | 34 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3381 | ntrC | transcriptional regulatory protein zraR (TIGR) | strong | 34 | 33 |
| | Rhizobium sp. OAE497 | ABIE40_RS16175 | | sigma-54 dependent transcriptional regulator | strong | 39 | 28 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0482 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 37 | 31 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_1146 | | Serine phosphatase RsbU, regulator of sigma subunit | insig. | 23 | 94 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0732 | | two-component system response regulator (NCBI ptt file) | no data | 36 | 29 |
| | Fusobacterium nucleatum SB010 | HUW76_03950 | | response regulator transcription factor | strong | 38 | 28 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS12005 | | response regulator transcription factor | insig. | 35 | 29 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1730 | | multi-sensor signal transduction histidine kinase (RefSeq) | insig. | 38 | 32 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_1292 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 33 | 28 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c07670 | | two component regulatory sytem | insig. | 37 | 35 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS04815 | | response regulator transcription factor | insig. | 34 | 29 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02438 | | response regulator receiver domain protein | insig. | 34 | 29 |
| | Rahnella sp. WP5 | EX31_RS20615 | | two-component system response regulator GlrR | insig. | 34 | 42 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS15005 | | two-component system response regulator | insig. | 37 | 34 |
| | Acinetobacter radioresistens SK82 | MPMX26_00655 | | Transcriptional regulatory protein QseB | no data | 35 | 28 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS14455 | | two-component system response regulator GlrR | strong | 33 | 41 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2149 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | strong | 29 | 36 |
| | Escherichia coli ECOR38 | HEPCGN_20640 | qseF | two-component system response regulator QseF/GlrR | strong | 33 | 41 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0196 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 34 | 32 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_10090 | | sigma-54-dependent response regulator transcription factor ZraR | insig. | 33 | 34 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3215 | drrA | response regulator (TIGR) | insig. | 36 | 28 |
| | Rhodospirillum rubrum S1H | Rru_A1385 | | Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family (NCBI) | cofit | 34 | 32 |
| | Pseudomonas simiae WCS417 | PS417_16365 | | transcriptional regulator | no data | 41 | 31 |
| | Pseudomonas sp. DMC3 | GFF4822 | | Transcriptional regulatory protein OmpR | insig. | 39 | 31 |
| | Pectobacterium carotovorum WPP14 | HER17_RS05925 | | two-component system response regulator GlrR | cofit | 32 | 41 |
| | Escherichia fergusonii Becca | EFB2_04606 | | Transcriptional regulatory protein ZraR | insig. | 34 | 29 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_04045 | | Transcriptional regulatory protein ZraR | insig. | 34 | 29 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS23090 | | sigma-54-dependent response regulator transcription factor ZraR | insig. | 34 | 29 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3601 | | Flagellar regulatory protein FleQ | insig. | 33 | 34 |
| | Escherichia coli BL21 | ECD_02446 | | response regulator regulating glmY sRNA in two-component system with sensor protein GlrK | sig. | 32 | 41 |
| | Escherichia fergusonii Becca | EFB2_01342 | | Transcriptional regulatory protein QseF | insig. | 32 | 41 |
| | Escherichia coli ECOR27 | NOLOHH_13170 | qseF | two-component system response regulator QseF/GlrR | cofit | 32 | 41 |
| | Escherichia coli ECRC100 | OKFHMN_21495 | qseF | two-component system response regulator QseF/GlrR | cofit | 32 | 41 |
| | Escherichia coli ECRC101 | MCAODC_12025 | qseF | two-component system response regulator QseF/GlrR | cofit | 32 | 41 |
| | Escherichia coli ECRC102 | NIAGMN_19265 | qseF | two-component system response regulator QseF/GlrR | cofit | 32 | 41 |