Conservation of cofitness between SMc03228 and SMc02867 in Sinorhizobium meliloti 1021

63 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc03228 YciI-like protein 1.0 SMc02867 multidrug-efflux system transmembrane protein 0.28 18
Rhizobium sp. OAE497 0.78 ABIE40_RS18050 YciI-like protein 0.50 ABIE40_RS24225 efflux RND transporter permease subunit low > 107
Agrobacterium fabrum C58 0.63 Atu2649 hypothetical protein 0.72 Atu3202 RND multidrug efflux transporter low > 89
Caulobacter crescentus NA1000 0.39 CCNA_00067 YciI-like protein 0.52 CCNA_00850 cation/multidrug efflux pump acrB2 low > 66
Caulobacter crescentus NA1000 Δfur 0.39 CCNA_00067 YciI-like protein 0.52 CCNA_00850 cation/multidrug efflux pump acrB2 low > 67
Pseudomonas stutzeri RCH2 0.39 Psest_1886 Uncharacterized protein conserved in bacteria 0.52 Psest_0310 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 67
Azospirillum brasilense Sp245 0.39 AZOBR_RS00285 hypothetical protein 0.57 AZOBR_RS05000 acriflavine resistance protein B low > 97
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS38165 YciI family protein 0.53 QEN71_RS02525 efflux RND transporter permease subunit low > 153
Pseudomonas sp. RS175 0.36 PFR28_03321 Protein YciI 0.63 PFR28_02463 Multidrug resistance protein MexB low > 88
Pseudomonas simiae WCS417 0.36 PS417_22285 hypothetical protein 0.61 PS417_12585 acriflavine resistance protein B low > 88
Alteromonas macleodii MIT1002 0.36 MIT1002_01424 YciI-like protein 0.49 MIT1002_00135 Multidrug-efflux transporter MexB 0.39 28
Dickeya dianthicola ME23 0.36 DZA65_RS10900 YciI family protein 0.51 DZA65_RS06115 multidrug efflux RND transporter permease subunit low > 75
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_18510 hypothetical protein 0.63 AO353_26845 acriflavine resistance protein B low > 101
Pseudomonas fluorescens SBW25 0.36 PFLU_RS23925 YciI family protein 0.62 PFLU_RS13280 multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.36 PFLU_RS23925 YciI family protein 0.62 PFLU_RS13280 multidrug efflux RND transporter permease subunit low > 109
Pseudomonas sp. S08-1 0.35 OH686_20785 YciL protein 0.54 OH686_16050 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) low > 80
Rahnella sp. WP5 0.35 EX31_RS10020 YciI family protein 0.54 EX31_RS22470 multidrug efflux RND transporter permease subunit low > 89
Dickeya dadantii 3937 0.35 DDA3937_RS10420 YciI family protein 0.57 DDA3937_RS07155 multidrug efflux RND transporter permease subunit low > 74
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_3549 YciL protein 0.64 Pf1N1B4_4772 RND efflux system, inner membrane transporter CmeB low > 87
Pseudomonas fluorescens FW300-N2C3 0.35 AO356_18485 hypothetical protein 0.63 AO356_28730 acriflavine resistance protein B — —
Pseudomonas syringae pv. syringae B728a 0.35 Psyr_3588 YCII-related protein 0.56 Psyr_2282 Hydrophobe/amphiphile efflux-1 HAE1 — —
Escherichia coli BL21 0.35 ECD_01225 putative DGPF domain-containing enzyme 0.53 ECD_00413 multidrug efflux system protein low > 60
Pseudomonas syringae pv. syringae B728a ΔmexB 0.35 Psyr_3588 YCII-related protein 0.56 Psyr_2282 Hydrophobe/amphiphile efflux-1 HAE1 — —
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_4407 YciL protein 0.63 PfGW456L13_2954 RND efflux system, inner membrane transporter CmeB low > 87
Escherichia coli BW25113 0.35 b1251 yciI orf, hypothetical protein (VIMSS) 0.53 b0462 acrB multidrug efflux system protein (NCBI) low > 76
Escherichia fergusonii Becca 0.35 EFB2_02674 Protein YciI 0.53 EFB2_03596 Multidrug efflux pump subunit AcrB low > 86
Escherichia coli Nissle 1917 0.35 ECOLIN_RS07555 YciI family protein 0.53 ECOLIN_RS02750 efflux RND transporter permease AcrB — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.35 OHPLBJKB_02432 Protein YciI 0.53 OHPLBJKB_03212 Multidrug efflux pump subunit AcrB — —
Shewanella loihica PV-4 0.34 Shew_2261 YciI-like protein (RefSeq) 0.51 Shew_0032 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) low > 60
Dechlorosoma suillum PS 0.34 Dsui_2887 hypothetical protein 0.58 Dsui_3182 hydrophobe/amphiphile efflux-1 (HAE1) family transporter — —
Dickeya dianthicola 67-19 0.34 HGI48_RS10425 YciI family protein 0.51 HGI48_RS05790 multidrug efflux RND transporter permease subunit low > 71
Kangiella aquimarina DSM 16071 0.34 B158DRAFT_2302 Uncharacterized protein conserved in bacteria 0.49 B158DRAFT_0733 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 40
Escherichia coli ECRC99 0.34 KEDOAH_25665 yciI YciI family protein 0.53 KEDOAH_19760 acrB efflux RND transporter permease AcrB — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.34 GFF2737 YciL protein 0.54 GFF4379 RND efflux system, inner membrane transporter CmeB low > 78
Escherichia coli ECOR38 0.34 HEPCGN_25135 yciI YciI family protein 0.53 HEPCGN_06820 acrB efflux RND transporter permease AcrB 0.63 75
Escherichia coli ECRC98 0.34 JDDGAC_05905 yciI YciI family protein 0.52 JDDGAC_25915 acrD multidrug efflux RND transporter permease AcrD — —
Escherichia coli ECRC101 0.34 MCAODC_21590 yciI YciI family protein 0.53 MCAODC_27430 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECRC101 0.34 OKFHMN_28670 yciI YciI family protein 0.53 OKFHMN_08205 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECRC102 0.34 NIAGMN_27565 yciI YciI family protein 0.53 NIAGMN_06260 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECOR27 0.34 NOLOHH_20380 yciI YciI family protein 0.53 NOLOHH_01140 acrB efflux RND transporter permease AcrB — —
Pseudomonas fluorescens FW300-N2E2 0.33 Pf6N2E2_5623 YciL protein 0.63 Pf6N2E2_1661 RND efflux system, inner membrane transporter CmeB low > 103
Acinetobacter radioresistens SK82 0.33 MPMX26_02640 Protein YciI 0.47 MPMX26_00689 Multidrug resistance protein MexB low > 36
Pectobacterium carotovorum WPP14 0.33 HER17_RS10975 YciI family protein 0.54 HER17_RS15740 multidrug efflux RND transporter permease subunit low > 75
Rhodanobacter denitrificans FW104-10B01 0.32 LRK54_RS00280 YciI family protein 0.48 LRK54_RS02100 multidrug efflux RND transporter permease subunit low > 59
Rhodanobacter denitrificans MT42 0.32 LRK55_RS18180 YciI family protein 0.48 LRK55_RS01875 multidrug efflux RND transporter permease subunit low > 63
Rhodospirillum rubrum S1H 0.32 Rru_A3572 YCII-related (NCBI) 0.68 Rru_A1118 Hydrophobe/amphiphile efflux-1 HAE1 (NCBI) low > 58
Erwinia tracheiphila SCR3 0.32 LU632_RS12835 YciI family protein 0.53 LU632_RS18185 efflux RND transporter permease subunit — —
Serratia liquefaciens MT49 0.32 IAI46_14115 YciI family protein 0.52 IAI46_18690 multidrug efflux RND transporter permease AcrD — —
Enterobacter sp. TBS_079 0.32 MPMX20_02577 Protein YciI 0.54 MPMX20_01064 Multidrug efflux pump subunit AcrB low > 85
Pseudomonas putida KT2440 0.31 PP_4502 putative enzyme 0.61 PP_3456 Multidrug resistance protein MexB low > 96
Klebsiella michiganensis M5al 0.31 BWI76_RS17195 hypothetical protein 0.54 BWI76_RS06775 multidrug efflux RND transporter permease subunit low > 92
Shewanella amazonensis SB2B 0.31 Sama_2138 YciI-like protein (RefSeq) 0.52 Sama_3554 AcrB/AcrD/AcrF family protein (RefSeq) low > 62
Rhodanobacter sp. FW510-T8 0.31 OKGIIK_07030 YciI family protein 0.49 OKGIIK_09170 Efflux pump membrane transporter low > 52
Pantoea sp. MT58 0.30 IAI47_09125 YciI family protein 0.52 IAI47_14515 multidrug efflux RND transporter permease subunit low > 76
Enterobacter asburiae PDN3 0.30 EX28DRAFT_0921 Uncharacterized protein conserved in bacteria 0.54 EX28DRAFT_2496 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 76
Shewanella sp. ANA-3 0.30 Shewana3_1504 YciI-like protein (RefSeq) 0.53 Shewana3_4045 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.30 SO3036 conserved hypothetical protein (NCBI ptt file) 0.53 SO4692 AcrB/AcrD/AcrF family protein (NCBI ptt file) low > 76
Xanthomonas campestris pv. campestris strain 8004 0.29 Xcc-8004.2360.1 YciL protein 0.52 Xcc-8004.1794.1 RND efflux system, inner membrane transporter CmeB low > 74
Paraburkholderia graminis OAS925 0.29 ABIE53_006363 uncharacterized protein YciI 0.53 ABIE53_003408 multidrug efflux pump low > 113
Dyella japonica UNC79MFTsu3.2 0.29 ABZR86_RS02840 YciI family protein 0.51 ABZR86_RS18285 efflux RND transporter permease subunit low > 74
Azospirillum sp. SherDot2 0.29 MPMX19_02041 Protein YciI 0.55 MPMX19_05884 Multidrug efflux pump subunit AcrB low > 112
Variovorax sp. OAS795 0.29 ABID97_RS29000 YciI family protein 0.59 ABID97_RS00325 efflux RND transporter permease subunit low > 91
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF1577 YciL protein 0.60 GFF3840 RND efflux system, inner membrane transporter CmeB low > 90
Cupriavidus basilensis FW507-4G11 0.27 RR42_RS32875 hypothetical protein 0.58 RR42_RS20650 multidrug efflux RND transporter permease subunit low > 128

Not shown: 5 genomes with orthologs for SMc03228 only; 17 genomes with orthologs for SMc02867 only