Conservation of cofitness between Pf6N2E2_5045 and Pf6N2E2_5723 in Pseudomonas fluorescens FW300-N2E2

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas fluorescens FW300-N2E2 1.0 Pf6N2E2_5045 Permease of the drug/metabolite transporter (DMT) superfamily 1.0 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.28 19
Pseudomonas fluorescens FW300-N2C3 0.98 AO356_15525 hypothetical protein 1.00 AO356_19060 (p)ppGpp synthetase low > 104
Pseudomonas sp. RS175 0.97 PFR28_03826 putative inner membrane transporter YedA 0.99 PFR28_03223 GTP pyrophosphokinase low > 88
Pseudomonas fluorescens FW300-N1B4 0.88 Pf1N1B4_2735 Permease of the drug/metabolite transporter (DMT) superfamily 0.98 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 87
Pseudomonas fluorescens GW456-L13 0.88 PfGW456L13_1408 Permease of the drug/metabolite transporter (DMT) superfamily 0.96 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 87
Pseudomonas simiae WCS417 0.84 PS417_24505 membrane protein 0.97 PS417_20150 (p)ppGpp synthetase
Pseudomonas fluorescens FW300-N2E3 0.84 AO353_06270 hypothetical protein 0.97 AO353_02710 (p)ppGpp synthetase low > 101
Pseudomonas fluorescens SBW25 0.84 PFLU_RS26430 drug/metabolite exporter YedA 0.97 PFLU_RS22095 GTP diphosphokinase low > 109
Pseudomonas fluorescens SBW25-INTG 0.84 PFLU_RS26430 drug/metabolite exporter YedA 0.97 PFLU_RS22095 GTP diphosphokinase low > 109
Pseudomonas putida KT2440 0.72 PP_4767 amino acid exporter for phenylalanine, threonine 0.91 PP_1656 ATP:GTP 3'-pyrophosphotransferase low > 96
Pseudomonas syringae pv. syringae B728a 0.69 Psyr_4298 Protein of unknown function DUF6 0.94 Psyr_3695 RelA/SpoT protein low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.69 Psyr_4298 Protein of unknown function DUF6 0.94 Psyr_3695 RelA/SpoT protein low > 86
Rahnella sp. WP5 0.56 EX31_RS23955 drug/metabolite exporter YedA 0.48 EX31_RS07955 GTP diphosphokinase low > 89
Serratia liquefaciens MT49 0.53 IAI46_07395 drug/metabolite exporter YedA 0.47 IAI46_03600 GTP diphosphokinase low > 86
Klebsiella michiganensis M5al 0.49 BWI76_RS18410 drug/metabolite exporter YedA 0.47 BWI76_RS22805 GTP diphosphokinase low > 92
Escherichia coli ECRC62 0.49 BNILDI_15030 yedA drug/metabolite exporter YedA 0.47 BNILDI_10630 relA GTP diphosphokinase low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF3998 Permease of the drug/metabolite transporter (DMT) superfamily 0.46 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 low > 78
Escherichia coli ECOR38 0.48 HEPCGN_03970 yedA drug/metabolite exporter YedA 0.47 HEPCGN_19500 relA GTP diphosphokinase low > 87
Escherichia coli ECOR27 0.46 NOLOHH_16240 yedA drug/metabolite exporter YedA 0.47 NOLOHH_12125 relA GTP diphosphokinase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.46 OHPLBJKB_01769 putative inner membrane transporter YedA 0.47 OHPLBJKB_00947 GTP pyrophosphokinase low > 73
Escherichia coli ECRC100 0.46 OKFHMN_25610 yedA drug/metabolite exporter YedA 0.47 OKFHMN_20250 relA GTP diphosphokinase low > 80
Escherichia coli Nissle 1917 0.46 ECOLIN_RS11140 drug/metabolite exporter YedA 0.47 ECOLIN_RS15515 GTP diphosphokinase low > 55
Escherichia coli ECRC99 0.46 KEDOAH_02485 yedA drug/metabolite exporter YedA 0.47 KEDOAH_07880 relA GTP diphosphokinase
Escherichia coli BW25113 0.46 b1959 yedA predicted inner membrane protein (NCBI) 0.47 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) low > 76
Escherichia coli ECRC102 0.46 NIAGMN_02445 yedA drug/metabolite exporter YedA 0.47 NIAGMN_18020 relA GTP diphosphokinase
Escherichia coli ECRC98 0.46 JDDGAC_00195 yedA drug/metabolite exporter YedA 0.47 JDDGAC_23915 relA GTP diphosphokinase low > 86
Escherichia coli ECRC101 0.46 MCAODC_19785 yedA drug/metabolite exporter YedA 0.47 MCAODC_10775 relA GTP diphosphokinase low > 87
Escherichia fergusonii Becca 0.46 EFB2_01988 putative inner membrane transporter YedA 0.47 EFB2_01133 GTP pyrophosphokinase low > 86
Dyella japonica UNC79MFTsu3.2 0.45 ABZR86_RS11675 drug/metabolite exporter YedA 0.41 ABZR86_RS19725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 74
Enterobacter sp. TBS_079 0.45 MPMX20_02955 putative inner membrane transporter YedA 0.46 MPMX20_03653 GTP pyrophosphokinase low > 85
Enterobacter asburiae PDN3 0.44 EX28DRAFT_0595 Predicted permease, DMT superfamily 0.46 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family low > 76
Rhodanobacter sp. FW510-T8 0.40 OKGIIK_11930 yedA drug/metabolite exporter YedA 0.40 OKGIIK_02170 relA GTP diphosphokinase low > 52
Rhodanobacter denitrificans MT42 0.39 LRK55_RS11680 drug/metabolite exporter YedA 0.41 LRK55_RS12430 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 63
Rhodanobacter denitrificans FW104-10B01 0.39 LRK54_RS11955 drug/metabolite exporter YedA 0.41 LRK54_RS12725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 59
Xanthomonas campestris pv. campestris strain 8004 0.38 Xcc-8004.4970.1 Permease of the drug/metabolite transporter (DMT) superfamily 0.38 Xcc-8004.1489.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 74
Lysobacter sp. OAE881 0.37 ABIE51_RS03200 drug/metabolite exporter YedA 0.36 ABIE51_RS05170 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 62
Cupriavidus basilensis FW507-4G11 0.31 RR42_RS31400 GntR family transcriptional regulator 0.38 RR42_RS06585 GTP pyrophosphokinase low > 128
Ralstonia solanacearum GMI1000 0.30 RS_RS21045 GntR family transcriptional regulator 0.39 RS_RS07930 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Variovorax sp. SCN45 0.30 GFF940 Permease of the drug/metabolite transporter (DMT) superfamily 0.34 GFF403 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 127
Ralstonia sp. UNC404CL21Col 0.29 ABZR87_RS20410 EamA family transporter 0.39 ABZR87_RS13745 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Ralstonia solanacearum PSI07 0.28 RPSI07_RS03405 GntR family transcriptional regulator 0.39 RPSI07_RS15685 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 81
Ralstonia solanacearum UW163 0.27 UW163_RS19390 GntR family transcriptional regulator 0.39 UW163_RS15115 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum IBSBF1503 0.27 RALBFv3_RS19785 GntR family transcriptional regulator 0.39 RALBFv3_RS01805 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 76
Acidovorax sp. GW101-3H11 0.27 Ac3H11_4554 Permease of the drug/metabolite transporter (DMT) superfamily 0.35 Ac3H11_362 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 79
Paraburkholderia sabiae LMG 24235 0.25 QEN71_RS05485 EamA family transporter 0.39 QEN71_RS05265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.42 31
Paraburkholderia graminis OAS925 0.23 ABIE53_002851 drug/metabolite transporter (DMT)-like permease 0.38 ABIE53_002905 GTP pyrophosphokinase low > 113
Burkholderia phytofirmans PsJN 0.23 BPHYT_RS13190 membrane protein 0.38 BPHYT_RS13655 GTP pyrophosphokinase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.23 H281DRAFT_00402 Permease of the drug/metabolite transporter (DMT) superfamily 0.38 H281DRAFT_04499 GTP pyrophosphokinase low > 103
Bacteroides thetaiotaomicron VPI-5482 0.22 BT1397 putative membrane protein (NCBI ptt file) 0.24 BT0700 GTP pyrophosphokinase (NCBI ptt file) low > 81
Phocaeicola dorei CL03T12C01 0.20 ABI39_RS19240 EamA family transporter 0.23 ABI39_RS14150 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 72
Pseudomonas sp. S08-1 0.17 OH686_04575 hypothetical protein 0.88 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I low > 80
Synechococcus elongatus PCC 7942 0.15 Synpcc7942_1917 permease of the drug/metabolite transporter 0.34 Synpcc7942_1377 metal dependent phosphohydrolase low > 38
Dechlorosoma suillum PS 0.11 Dsui_1370 putative permease, DMT superfamily 0.41 Dsui_2816 (p)ppGpp synthetase, RelA/SpoT family low > 51
Shewanella loihica PV-4 0.09 Shew_3337 hypothetical protein (RefSeq) 0.46 Shew_1202 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 60

Not shown: 5 genomes with orthologs for Pf6N2E2_5045 only; 25 genomes with orthologs for Pf6N2E2_5723 only