Conservation of cofitness between Pf1N1B4_4665 and Pf1N1B4_2718 in Pseudomonas fluorescens FW300-N1B4

63 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas fluorescens FW300-N1B4 1.0 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 1.0 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.29 8
Pseudomonas fluorescens GW456-L13 0.95 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.92 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 87
Pseudomonas fluorescens FW300-N2E3 0.92 AO353_22895 multidrug transporter 0.92 AO353_06350 hydrogenase low > 101
Pseudomonas fluorescens FW300-N2C3 0.91 AO356_25875 multidrug transporter 0.92 AO356_15435 hydrogenase low > 104
Pseudomonas fluorescens FW300-N2E2 0.91 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.91 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 103
Pseudomonas sp. RS175 0.90 PFR28_02194 Multidrug resistance protein MdtB 0.89 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 88
Pseudomonas simiae WCS417 0.89 PS417_12745 multidrug transporter 0.92 PS417_24600 hydrogenase low > 88
Pseudomonas fluorescens SBW25 0.89 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.93 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 109
Pseudomonas fluorescens SBW25-INTG 0.89 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.93 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.31 10
Pseudomonas putida KT2440 0.85 PP_3584 multidrug efflux transport system - membrane subunit 0.86 PP_4782 Phosphomethylpyrimidine kinase low > 96
Pseudomonas syringae pv. syringae B728a 0.84 Psyr_2483 Acriflavin resistance protein 0.86 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.84 Psyr_2483 Acriflavin resistance protein 0.86 Psyr_4340 phosphomethylpyrimidine kinase, putative low > 86
Pseudomonas stutzeri RCH2 0.75 Psest_2139 Cation/multidrug efflux pump 0.77 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 67
Ralstonia sp. UNC404CL21Col 0.70 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.27 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Herbaspirillum seropedicae SmR1 0.70 HSERO_RS07650 multidrug transporter 0.28 HSERO_RS02135 phosphomethylpyrimidine kinase low > 78
Ralstonia solanacearum GMI1000 0.69 RS_RS22915 multidrug transporter subunit MdtB 0.28 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum UW163 0.69 UW163_RS21010 multidrug transporter subunit MdtB 0.28 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum PSI07 0.69 RPSI07_RS05515 multidrug transporter subunit MdtB 0.28 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Ralstonia solanacearum IBSBF1503 0.69 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.28 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Cupriavidus basilensis FW507-4G11 0.65 RR42_RS03310 multidrug transporter 0.21 RR42_RS01370 phosphomethylpyrimidine kinase — —
Pectobacterium carotovorum WPP14 0.63 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.24 HER17_RS06265 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Dickeya dianthicola ME23 0.62 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.19 DZA65_RS16235 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Hydrogenophaga sp. GW460-11-11-14-LB1 0.62 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.25 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 90
Enterobacter asburiae PDN3 0.62 EX28DRAFT_0483 Cation/multidrug efflux pump 0.20 EX28DRAFT_0469 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Erwinia tracheiphila SCR3 0.62 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.19 LU632_RS08590 thiD bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Enterobacter sp. TBS_079 0.62 MPMX20_03061 Multidrug resistance protein MdtB 0.21 MPMX20_03076 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 85
Escherichia coli BW25113 0.62 b2075 mdtB multidrug efflux system, subunit B (NCBI) 0.22 b2103 thiD phosphomethylpyrimidine kinase (NCBI) low > 76
Escherichia fergusonii Becca 0.62 EFB2_01780 Multidrug resistance protein MdtB 0.21 EFB2_01754 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 86
Dickeya dadantii 3937 0.62 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.19 DDA3937_RS15335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 74
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.21 EX31_RS20390 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 89
Escherichia coli HS(pFamp)R (ATCC 700891) 0.62 OHPLBJKB_01629 Multidrug resistance protein MdtB 0.22 OHPLBJKB_01607 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase low > 73
Escherichia coli Nissle 1917 0.62 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 0.21 ECOLIN_RS12335 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC102 0.61 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 0.21 NIAGMN_22020 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Dickeya dianthicola 67-19 0.61 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.19 HGI48_RS15410 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 71
Escherichia coli BL21 0.61 ECD_01980 multidrug efflux system, subunit B 0.21 ECD_02031 hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase low > 61
Escherichia coli ECRC99 0.61 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 0.21 KEDOAH_04075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC62 0.61 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 0.22 BNILDI_14330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Escherichia coli ECRC100 0.61 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 0.21 OKFHMN_24075 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 80
Escherichia coli ECRC98 0.61 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 0.21 JDDGAC_28185 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECOR27 0.61 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 0.22 NOLOHH_15415 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 75
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.22 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Escherichia coli ECRC101 0.61 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 0.21 MCAODC_21085 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 87
Klebsiella michiganensis M5al 0.61 BWI76_RS19255 multidrug transporter subunit MdtB 0.21 BWI76_RS19375 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 92
Serratia liquefaciens MT49 0.61 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.22 IAI46_19100 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 86
Escherichia coli ECOR38 0.61 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 0.21 HEPCGN_02760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 87
Paraburkholderia bryophila 376MFSha3.1 0.61 H281DRAFT_06492 multidrug efflux pump 0.23 H281DRAFT_00587 hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase — —
Castellaniella sp019104865 MT123 0.61 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.18 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.61 GFF3854 Multidrug transporter MdtB 0.20 GFF3834 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) low > 78
Pantoea sp. MT58 0.60 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.17 IAI47_06810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 76
Paraburkholderia graminis OAS925 0.60 ABIE53_001783 multidrug efflux pump 0.21 ABIE53_002529 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Burkholderia phytofirmans PsJN 0.60 BPHYT_RS07785 multidrug transporter 0.20 BPHYT_RS12250 phosphomethylpyrimidine kinase — —
Azospirillum sp. SherDot2 0.58 MPMX19_05477 Multidrug resistance protein MdtB 0.22 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —
Magnetospirillum magneticum AMB-1 0.54 AMB_RS17370 acriflavine resistance protein B 0.23 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.22 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Rhodopseudomonas palustris CGA009 0.52 TX73_018025 multidrug efflux RND transporter permease subunit 0.23 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS16320 efflux RND transporter permease subunit 0.25 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Xanthomonas campestris pv. campestris strain 8004 0.50 Xcc-8004.4792.1 Acriflavin resistance protein 0.26 Xcc-8004.3091.1 hypothetical protein low > 74
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB 0.23 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 52
Desulfovibrio vulgaris Hildenborough JW710 0.45 DVU0438 AcrB/AcrD/AcrF family protein (TIGR) 0.20 DVU0931 thiD phosphomethylpyrimidine kinase (TIGR) — —
Azospirillum brasilense Sp245 0.45 AZOBR_RS14670 multidrug transporter 0.24 AZOBR_RS07045 phosphomethylpyrimidine kinase — —
Desulfovibrio vulgaris Miyazaki F 0.45 DvMF_1515 acriflavin resistance protein (RefSeq) 0.21 DvMF_1376 phosphomethylpyrimidine kinase (RefSeq) — —
Bosea sp. OAE506 0.44 ABIE41_RS20140 efflux RND transporter permease subunit 0.23 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase — —
Rhizobium sp. OAE497 0.38 ABIE40_RS05760 efflux RND transporter permease subunit 0.22 ABIE40_RS25930 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase low > 107
Acinetobacter radioresistens SK82 0.23 MPMX26_02516 Multidrug resistance protein MdtC 0.34 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase — —

Not shown: 5 genomes with orthologs for Pf1N1B4_4665 only; 26 genomes with orthologs for Pf1N1B4_2718 only