Conservation of cofitness between IAI46_01035 and IAI46_03600 in Serratia liquefaciens MT49

54 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Serratia liquefaciens MT49 1.0 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1.0 IAI46_03600 GTP diphosphokinase 0.83 6
Rahnella sp. WP5 0.86 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.90 EX31_RS07955 GTP diphosphokinase low > 89
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.88 HER17_RS04115 GTP diphosphokinase low > 75
Dickeya dianthicola ME23 0.86 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.89 DZA65_RS18145 GTP diphosphokinase low > 75
Dickeya dianthicola 67-19 0.86 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.89 HGI48_RS17070 GTP diphosphokinase low > 71
Dickeya dadantii 3937 0.86 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.89 DDA3937_RS17015 GTP diphosphokinase low > 74
Escherichia coli ECOR38 0.84 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 HEPCGN_19500 relA GTP diphosphokinase 0.92 54
Klebsiella michiganensis M5al 0.84 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.86 BWI76_RS22805 GTP diphosphokinase low > 92
Escherichia fergusonii Becca 0.84 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.86 EFB2_01133 GTP pyrophosphokinase 0.31 62
Escherichia coli Nissle 1917 0.84 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.86 ECOLIN_RS15515 GTP diphosphokinase low > 55
Escherichia coli BL21 0.84 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.86 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase low > 61
Enterobacter asburiae PDN3 0.84 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.86 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.84 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.86 OHPLBJKB_00947 GTP pyrophosphokinase low > 73
Escherichia coli BW25113 0.84 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 0.86 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.84 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.86 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 low > 78
Escherichia coli ECRC62 0.84 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 BNILDI_10630 relA GTP diphosphokinase low > 75
Escherichia coli ECRC102 0.84 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 NIAGMN_18020 relA GTP diphosphokinase
Escherichia coli ECOR27 0.84 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 NOLOHH_12125 relA GTP diphosphokinase low > 75
Escherichia coli ECRC100 0.84 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 OKFHMN_20250 relA GTP diphosphokinase low > 80
Escherichia coli ECRC99 0.84 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 KEDOAH_07880 relA GTP diphosphokinase
Escherichia coli ECRC98 0.84 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 JDDGAC_23915 relA GTP diphosphokinase low > 86
Pantoea sp. MT58 0.84 IAI47_18310 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.86 IAI47_04120 GTP diphosphokinase 0.57 11
Escherichia coli ECRC101 0.84 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.86 MCAODC_10775 relA GTP diphosphokinase low > 87
Erwinia tracheiphila SCR3 0.83 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.88 LU632_RS06350 relA GTP diphosphokinase low > 74
Enterobacter sp. TBS_079 0.83 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.86 MPMX20_03653 GTP pyrophosphokinase low > 85
Pseudomonas fluorescens FW300-N2E2 0.60 Pf6N2E2_5472 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.48 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 103
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.66 CSW01_12405 GTP diphosphokinase low > 62
Pseudomonas fluorescens FW300-N1B4 0.60 Pf1N1B4_783 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.48 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 87
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_16215 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.47 AO353_02710 (p)ppGpp synthetase low > 101
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_17740 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.48 AO356_19060 (p)ppGpp synthetase low > 104
Pseudomonas sp. RS175 0.59 PFR28_03477 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.48 PFR28_03223 GTP pyrophosphokinase low > 88
Pseudomonas stutzeri RCH2 0.59 Psest_1452 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.47 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family low > 67
Pseudomonas fluorescens GW456-L13 0.58 PfGW456L13_3767 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.48 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 87
Castellaniella sp019104865 MT123 0.58 ABCV34_RS04445 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.33 ABCV34_RS08440 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 48
Pseudomonas fluorescens SBW25 0.58 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.47 PFLU_RS22095 GTP diphosphokinase low > 109
Pseudomonas fluorescens SBW25-INTG 0.58 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.47 PFLU_RS22095 GTP diphosphokinase low > 109
Pseudomonas sp. S08-1 0.58 OH686_20470 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.47 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I low > 80
Paraburkholderia sabiae LMG 24235 0.56 QEN71_RS19725 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.36 QEN71_RS05265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 153
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS20880 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.36 ABZR87_RS13745 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Shewanella oneidensis MR-1 0.56 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.59 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) 0.92 40
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.59 Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 73
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.59 Shew_1202 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 60
Marinobacter adhaerens HP15 0.55 HP15_457 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.44 HP15_791 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA low > 73
Variovorax sp. SCN45 0.55 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) 0.31 GFF403 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 127
Ralstonia solanacearum GMI1000 0.54 RS_RS20360 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.36 RS_RS07930 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Ralstonia solanacearum PSI07 0.54 RPSI07_RS02545 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.36 RPSI07_RS15685 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 81
Ralstonia solanacearum UW163 0.54 UW163_RS18855 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.36 UW163_RS15115 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum IBSBF1503 0.54 RALBFv3_RS20320 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.36 RALBFv3_RS01805 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 76
Acidovorax sp. GW101-3H11 0.54 Ac3H11_2345 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.33 Ac3H11_362 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 79
Burkholderia phytofirmans PsJN 0.53 BPHYT_RS26655 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.34 BPHYT_RS13655 GTP pyrophosphokinase low > 109
Shewanella amazonensis SB2B 0.53 Sama_2627 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.58 Sama_1033 GTP diphosphokinase (RefSeq) 0.93 46
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS30660 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.35 RR42_RS06585 GTP pyrophosphokinase low > 128
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.40 ABZR86_RS19725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 74
Rhodanobacter denitrificans FW104-10B01 0.48 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.39 LRK54_RS12725 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.61 4
Rhodanobacter denitrificans MT42 0.48 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.39 LRK55_RS12430 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 63

Not shown: 13 genomes with orthologs for IAI46_01035 only; 17 genomes with orthologs for IAI46_03600 only