Conservation of cofitness between HER17_RS15910 and HER17_RS05560 in Pectobacterium carotovorum WPP14

57 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS15910 2-dehydropantoate 2-reductase 1.0 HER17_RS05560 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.96 1
Dickeya dianthicola ME23 0.79 DZA65_RS05940 2-dehydropantoate 2-reductase 0.81 DZA65_RS17155 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.90 2
Dickeya dadantii 3937 0.79 DDA3937_RS05555 2-dehydropantoate 2-reductase 0.81 DDA3937_RS15955 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.95 3
Dickeya dianthicola 67-19 0.79 HGI48_RS05615 2-dehydropantoate 2-reductase 0.81 HGI48_RS16070 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.86 4
Serratia liquefaciens MT49 0.69 IAI46_04950 2-dehydropantoate 2-reductase 0.79 IAI46_21240 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Enterobacter sp. TBS_079 0.63 MPMX20_01016 2-dehydropantoate 2-reductase 0.78 MPMX20_00827 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 85
Enterobacter asburiae PDN3 0.63 EX28DRAFT_2546 2-dehydropantoate 2-reductase 0.77 EX28DRAFT_3730 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.80 6
Klebsiella michiganensis M5al 0.63 BWI76_RS06405 2-dehydropantoate 2-reductase 0.77 BWI76_RS04995 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 92
Rahnella sp. WP5 0.63 EX31_RS22180 2-dehydropantoate 2-reductase 0.80 EX31_RS03280 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 89
Escherichia coli ECOR38 0.63 HEPCGN_07025 panE 2-dehydropantoate 2-reductase 0.78 HEPCGN_08375 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.53 77
Escherichia fergusonii Becca 0.63 EFB2_03632 2-dehydropantoate 2-reductase 0.77 EFB2_03910 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Escherichia coli BW25113 0.63 b0425 panE 2-dehydropantoate 2-reductase (NCBI) 0.78 b0134 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI) low > 76
Escherichia coli Nissle 1917 0.63 ECOLIN_RS02560 2-dehydropantoate 2-reductase 0.77 ECOLIN_RS00745 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli BL21 0.63 ECD_00373 2-dehydropantoate reductase, NADPH-specific 0.78 ECD_00133 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 61
Escherichia coli ECOR27 0.62 NOLOHH_01345 panE 2-dehydropantoate 2-reductase 0.78 NOLOHH_02745 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.70 20
Escherichia coli ECRC62 0.62 BNILDI_22760 panE 2-dehydropantoate 2-reductase 0.78 BNILDI_08925 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.85 5
Escherichia coli HS(pFamp)R (ATCC 700891) 0.62 OHPLBJKB_03251 2-dehydropantoate 2-reductase 0.78 OHPLBJKB_03527 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 73
Escherichia coli ECRC100 0.61 OKFHMN_08395 panE 2-dehydropantoate 2-reductase 0.78 OKFHMN_10400 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 80
Escherichia coli ECRC99 0.61 KEDOAH_19570 panE 2-dehydropantoate 2-reductase 0.77 KEDOAH_17755 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC101 0.61 MCAODC_27620 panE 2-dehydropantoate 2-reductase 0.78 MCAODC_00915 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.68 42
Escherichia coli ECRC102 0.61 NIAGMN_06450 panE 2-dehydropantoate 2-reductase 0.78 NIAGMN_08250 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Escherichia coli ECRC98 0.61 JDDGAC_12050 panE 2-dehydropantoate 2-reductase 0.78 JDDGAC_13995 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 86
Pantoea sp. MT58 0.61 IAI47_14715 2-dehydropantoate 2-reductase 0.72 IAI47_15655 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 76
Erwinia tracheiphila SCR3 0.58 LU632_RS18455 panE 2-dehydropantoate 2-reductase 0.76 LU632_RS20100 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF4336 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.77 GFF91 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 78
Vibrio cholerae E7946 ATCC 55056 0.34 CSW01_11730 2-dehydropantoate 2-reductase 0.67 CSW01_03135 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas stutzeri RCH2 0.25 Psest_1140 2-dehydropantoate 2-reductase 0.52 Psest_0996 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Shewanella sp. ANA-3 0.25 Shewana3_0780 2-dehydropantoate 2-reductase (RefSeq) 0.62 Shewana3_3408 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) 0.78 1
Shewanella oneidensis MR-1 0.24 SO3817 panE 2-dehydropantoate 2-reductase (NCBI ptt file) 0.63 SO0870 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI ptt file) 0.86 2
Pseudomonas sp. S08-1 0.24 OH686_08220 2-dehydropantoate 2-reductase 0.56 OH686_17245 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Shewanella amazonensis SB2B 0.22 Sama_2559 2-dehydropantoate 2-reductase (RefSeq) 0.63 Sama_0776 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Pseudomonas fluorescens GW456-L13 0.21 PfGW456L13_1839 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.55 PfGW456L13_1521 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 87
Pseudomonas simiae WCS417 0.21 PS417_22515 2-dehydropantoate 2-reductase 0.55 PS417_23910 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 88
Pseudomonas fluorescens FW300-N2C3 0.21 AO356_17955 2-dehydropantoate 2-reductase 0.56 AO356_16060 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.29 30
Pseudomonas fluorescens FW300-N2E3 0.21 AO353_03645 2-dehydropantoate 2-reductase 0.56 AO353_14385 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 101
Pseudomonas fluorescens FW300-N2E2 0.21 Pf6N2E2_5521 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.56 Pf6N2E2_5153 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) 0.29 31
Pseudomonas fluorescens SBW25 0.21 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.54 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 109
Shewanella loihica PV-4 0.21 Shew_2895 2-dehydropantoate 2-reductase (RefSeq) 0.64 Shew_3133 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Pseudomonas fluorescens FW300-N1B4 0.21 Pf1N1B4_651 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.55 Pf1N1B4_2854 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 87
Pseudomonas fluorescens SBW25-INTG 0.21 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.54 PFLU_RS25750 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.36 25
Alteromonas macleodii MIT1002 0.20 MIT1002_01217 2-dehydropantoate 2-reductase 0.64 MIT1002_03694 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Pseudomonas sp. RS175 0.20 PFR28_03426 2-dehydropantoate 2-reductase 0.57 PFR28_03721 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.39 21
Pseudomonas putida KT2440 0.20 PP_1351 putative 2-dehydropantoate 2-reductase 0.56 PP_4699 3-methyl-2-oxobutanoate hydroxymethyltransferase 0.31 7
Pseudomonas syringae pv. syringae B728a ΔmexB 0.19 Psyr_4088 ketopantoate reductase 0.55 Psyr_0828 ketopantoate hydroxymethyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.19 Psyr_4088 ketopantoate reductase 0.55 Psyr_0828 ketopantoate hydroxymethyltransferase — —
Marinobacter adhaerens HP15 0.19 HP15_1312 2-dehydropantoate 2-reductase 0.56 HP15_324 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Herbaspirillum seropedicae SmR1 0.14 HSERO_RS09230 2-dehydropantoate 2-reductase 0.52 HSERO_RS03085 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 78
Variovorax sp. OAS795 0.14 ABID97_RS24580 2-dehydropantoate 2-reductase 0.36 ABID97_RS07435 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 91
Cupriavidus basilensis FW507-4G11 0.13 RR42_RS32960 2-dehydropantoate 2-reductase 0.45 RR42_RS17250 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Variovorax sp. SCN45 0.12 GFF3590 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.37 GFF2579 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) low > 127
Ralstonia sp. UNC404CL21Col 0.12 ABZR87_RS15450 2-dehydropantoate 2-reductase 0.51 ABZR87_RS00950 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Dinoroseobacter shibae DFL-12 0.11 Dshi_1216 2-dehydropantoate 2-reductase (RefSeq) 0.30 Dshi_2966 3-methyl-2-oxobutanoate hydroxymethyltransferase (RefSeq) — —
Rhodanobacter denitrificans FW104-10B01 0.10 LRK54_RS03070 2-dehydropantoate 2-reductase 0.47 LRK54_RS15115 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodanobacter denitrificans MT42 0.10 LRK55_RS02820 2-dehydropantoate 2-reductase 0.47 LRK55_RS14830 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 63
Burkholderia phytofirmans PsJN 0.10 BPHYT_RS21975 2-dehydropantoate 2-reductase 0.49 BPHYT_RS03605 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Paraburkholderia graminis OAS925 0.09 ABIE53_004184 2-dehydropantoate 2-reductase 0.51 ABIE53_000867 3-methyl-2-oxobutanoate hydroxymethyltransferase — —
Rhodanobacter sp. FW510-T8 0.09 OKGIIK_09940 panE 2-dehydropantoate 2-reductase 0.46 OKGIIK_03885 panB 3-methyl-2-oxobutanoate hydroxymethyltransferase low > 52
Ralstonia solanacearum GMI1000 0.08 RS_RS00860 2-dehydropantoate 2-reductase 0.53 RS_RS13180 3-methyl-2-oxobutanoate hydroxymethyltransferase — —

Not shown: 3 genomes with orthologs for HER17_RS15910 only; 41 genomes with orthologs for HER17_RS05560 only