Conservation of cofitness between HEPCGN_02885 and HEPCGN_00770 in Escherichia coli ECOR38

61 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 HEPCGN_00770 ahpC alkyl hydroperoxide reductase subunit C 0.68 4
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_20460 ahpC alkyl hydroperoxide reductase subunit C — —
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 JDDGAC_11155 ahpC alkyl hydroperoxide reductase subunit C low > 86
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 OKFHMN_07510 ahpC alkyl hydroperoxide reductase subunit C low > 80
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NIAGMN_05565 ahpC alkyl hydroperoxide reductase subunit C — —
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NOLOHH_23885 ahpC alkyl hydroperoxide reductase subunit C low > 75
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 1.00 ECOLIN_RS03320 alkyl hydroperoxide reductase subunit C low > 55
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 1.00 EFB2_03486 Alkyl hydroperoxide reductase C low > 86
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b0605 ahpC alkyl hydroperoxide reductase, C22 subunit (NCBI) low > 76
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_26725 ahpC alkyl hydroperoxide reductase subunit C low > 87
Escherichia coli ECRC62 0.99 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 BNILDI_21895 ahpC alkyl hydroperoxide reductase subunit C low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01629 Multidrug resistance protein MdtB 1.00 OHPLBJKB_03100 Alkyl hydroperoxide reductase C low > 73
Escherichia coli BL21 0.99 ECD_01980 multidrug efflux system, subunit B 1.00 ECD_00574 alkyl hydroperoxide reductase, C22 subunit low > 61
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.99 BWI76_RS07940 alkyl hydroperoxide reductase subunit C low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3854 Multidrug transporter MdtB 0.99 GFF4513 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) low > 78
Enterobacter sp. TBS_079 0.90 MPMX20_03061 Multidrug resistance protein MdtB 0.99 MPMX20_01271 Alkyl hydroperoxide reductase C low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0483 Cation/multidrug efflux pump 0.99 EX28DRAFT_2350 peroxiredoxin low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.33 IAI46_04825 peroxiredoxin C low > 86
Pantoea sp. MT58 0.81 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.93 IAI47_06790 alkyl hydroperoxide reductase subunit C low > 76
Erwinia tracheiphila SCR3 0.79 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.33 LU632_RS18475 peroxiredoxin C low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.90 HER17_RS02545 alkyl hydroperoxide reductase subunit C low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.90 DDA3937_RS02515 alkyl hydroperoxide reductase subunit C low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.90 DZA65_RS02565 alkyl hydroperoxide reductase subunit C low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.90 HGI48_RS02460 alkyl hydroperoxide reductase subunit C low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.72 HSERO_RS21540 alkyl hydroperoxide reductase subunit C low > 78
Ralstonia solanacearum UW163 0.65 UW163_RS21010 multidrug transporter subunit MdtB 0.61 UW163_RS22815 peroxiredoxin — —
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.61 RALBFv3_RS22270 peroxiredoxin low > 76
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.61 RPSI07_RS00930 peroxiredoxin low > 81
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.62 ABZR87_RS17235 alkyl hydroperoxide reductase subunit C low > 80
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.62 RS_RS18335 peroxiredoxin low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.28 RR42_RS07870 alkyl hydroperoxide reductase low > 128
Pseudomonas sp. RS175 0.62 PFR28_02194 Multidrug resistance protein MdtB 0.74 PFR28_02482 Alkyl hydroperoxide reductase C low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.74 AO356_22805 alkyl hydroperoxide reductase low > 104
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.32 EX31_RS22080 peroxiredoxin C low > 89
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.74 Pf6N2E2_447 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) low > 103
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.74 PP_2439 peroxiredoxin, alkylhydroperoxide reductase - small subunit low > 96
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.64 OH686_18680 peroxiredoxin low > 80
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.74 PfGW456L13_2927 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.74 AO353_26965 alkyl hydroperoxide reductase low > 101
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.74 PFLU_RS14570 peroxiredoxin low > 109
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.74 PFLU_RS14570 peroxiredoxin low > 109
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.74 Pf1N1B4_5011 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) — —
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.74 PS417_14045 alkyl hydroperoxide reductase 0.35 9
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.71 QEN71_RS13380 alkyl hydroperoxide reductase subunit C low > 153
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.72 H281DRAFT_02890 peroxiredoxin (alkyl hydroperoxide reductase subunit C) low > 103
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.60 Ac3H11_233 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) — —
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.74 Psyr_2975 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.74 Psyr_2975 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.65 Psest_1133 peroxiredoxin — —
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.71 BPHYT_RS26845 alkyl hydroperoxide reductase subunit C — —
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.72 ABIE53_005904 peroxiredoxin low > 113
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.74 ABCV34_RS09920 alkyl hydroperoxide reductase subunit C low > 48
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.61 GFF2826 Alkyl hydroperoxide reductase protein C (EC 1.11.1.15) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.60 GFF3914 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) low > 90
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.61 ABID97_RS10800 alkyl hydroperoxide reductase subunit C low > 91
Azospirillum sp. SherDot2 0.53 MPMX19_05477 Multidrug resistance protein MdtB 0.75 MPMX19_05835 Alkyl hydroperoxide reductase C low > 112
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS09845 efflux RND transporter permease subunit 0.77 LRK54_RS00705 alkyl hydroperoxide reductase subunit C low > 59
Rhodanobacter denitrificans MT42 0.50 LRK55_RS09505 efflux RND transporter permease subunit 0.77 LRK55_RS00480 alkyl hydroperoxide reductase subunit C low > 63
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS16320 efflux RND transporter permease subunit 0.76 ABZR86_RS08490 alkyl hydroperoxide reductase subunit C low > 74
Rhodanobacter sp. FW510-T8 0.49 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB 0.77 OKGIIK_06555 ahpC alkyl hydroperoxide reductase subunit C low > 52
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4792.1 Acriflavin resistance protein 0.61 Xcc-8004.4221.1 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) low > 74
Parabacteroides merdae CL09T00C40 0.24 HMPREF1078_RS05470 efflux RND transporter permease subunit 0.68 HMPREF1078_RS04205 alkyl hydroperoxide reductase subunit C low > 61

Not shown: 3 genomes with orthologs for HEPCGN_02885 only; 30 genomes with orthologs for HEPCGN_00770 only