Conservation of cofitness between ECD_03708 and ECD_03650 in Escherichia coli BL21

55 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 1.0 ECD_03650 l-threonine dehydratase, biosynthetic; also known as threonine deaminase 0.93 18
Escherichia coli Nissle 1917 1.00 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.99 ECOLIN_RS21670 threonine ammonia-lyase, biosynthetic low > 55
Escherichia fergusonii Becca 1.00 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.99 EFB2_04864 L-threonine dehydratase biosynthetic IlvA low > 86
Escherichia coli BW25113 1.00 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 1.00 b3772 ilvA threonine dehydratase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 OHPLBJKB_04281 L-threonine dehydratase biosynthetic IlvA low > 73
Escherichia coli ECOR27 0.99 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 NOLOHH_06770 ilvA threonine ammonia-lyase, biosynthetic 0.79 65
Escherichia coli ECRC62 0.99 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 BNILDI_04755 ilvA threonine ammonia-lyase, biosynthetic 0.98 15
Escherichia coli ECOR38 0.99 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 HEPCGN_13345 ilvA threonine ammonia-lyase, biosynthetic 0.93 50
Escherichia coli ECRC100 0.99 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 OKFHMN_14635 ilvA threonine ammonia-lyase, biosynthetic 0.99 7
Escherichia coli ECRC101 0.99 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 MCAODC_05140 ilvA threonine ammonia-lyase, biosynthetic 0.94 20
Escherichia coli ECRC99 0.99 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 KEDOAH_13515 ilvA threonine ammonia-lyase, biosynthetic
Escherichia coli ECRC98 0.99 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 JDDGAC_18255 ilvA threonine ammonia-lyase, biosynthetic low > 86
Escherichia coli ECRC102 0.99 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 NIAGMN_12390 ilvA threonine ammonia-lyase, biosynthetic
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.92 EX28DRAFT_4444 threonine ammonia-lyase, biosynthetic, long form 0.74 25
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.93 GFF2900 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.94 BWI76_RS00980 PLP-dependent threonine dehydratase low > 92
Enterobacter sp. TBS_079 0.94 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.93 MPMX20_04498 L-threonine dehydratase biosynthetic IlvA 0.31 55
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.83 HER17_RS01080 threonine ammonia-lyase, biosynthetic 0.63 40
Dickeya dadantii 3937 0.85 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.86 DDA3937_RS20150 threonine ammonia-lyase, biosynthetic 0.47 56
Dickeya dianthicola ME23 0.85 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.85 DZA65_RS21330 threonine ammonia-lyase, biosynthetic 0.53 17
Dickeya dianthicola 67-19 0.85 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.87 HGI48_RS20290 threonine ammonia-lyase, biosynthetic 0.81 41
Erwinia tracheiphila SCR3 0.84 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.83 LU632_RS24395 ilvA threonine ammonia-lyase, biosynthetic low > 74
Serratia liquefaciens MT49 0.84 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.84 IAI46_24340 threonine ammonia-lyase, biosynthetic low > 86
Rahnella sp. WP5 0.83 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.81 EX31_RS15010 threonine ammonia-lyase, biosynthetic low > 89
Pantoea sp. MT58 0.83 IAI47_18310 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.83 IAI47_01040 threonine ammonia-lyase, biosynthetic low > 76
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_5472 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.50 Pf6N2E2_3938 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 103
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_783 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.49 Pf1N1B4_2280 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 87
Pseudomonas sp. RS175 0.61 PFR28_03477 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.49 PFR28_04834 L-threonine dehydratase biosynthetic IlvA low > 88
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_16215 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.50 AO353_08485 threonine dehydratase low > 101
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_17740 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.49 AO356_10330 threonine dehydratase low > 104
Pseudomonas stutzeri RCH2 0.60 Psest_1452 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.51 Psest_3866 threonine ammonia-lyase, biosynthetic, long form 0.35 51
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.67 CSW01_00135 threonine ammonia-lyase, biosynthetic low > 62
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_3767 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.49 PfGW456L13_949 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 87
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.49 PFLU_RS28665 threonine ammonia-lyase, biosynthetic low > 109
Pseudomonas fluorescens SBW25 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.49 PFLU_RS28665 threonine ammonia-lyase, biosynthetic low > 109
Castellaniella sp019104865 MT123 0.59 ABCV34_RS04445 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.50 ABCV34_RS14460 threonine ammonia-lyase, biosynthetic low > 48
Pseudomonas sp. S08-1 0.59 OH686_20470 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.51 OH686_11400 threonine ammonia-lyase, biosynthetic low > 80
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS19725 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.49 QEN71_RS01985 threonine ammonia-lyase, biosynthetic 0.66 9
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS20880 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.47 ABZR87_RS07360 threonine ammonia-lyase, biosynthetic low > 80
Ralstonia solanacearum PSI07 0.55 RPSI07_RS02545 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.50 RPSI07_RS21810 threonine ammonia-lyase, biosynthetic low > 81
Ralstonia solanacearum GMI1000 0.55 RS_RS20360 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.49 RS_RS02225 threonine ammonia-lyase, biosynthetic
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2345 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.50 Ac3H11_2042 Threonine dehydratase biosynthetic (EC 4.3.1.19) 0.75 49
Ralstonia solanacearum UW163 0.55 UW163_RS18855 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.47 UW163_RS02190 threonine ammonia-lyase, biosynthetic
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS20320 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.47 RALBFv3_RS11395 threonine ammonia-lyase, biosynthetic low > 76
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.56 Shewana3_0359 threonine dehydratase (RefSeq) low > 73
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.54 Shew_0293 threonine dehydratase (RefSeq) low > 60
Variovorax sp. SCN45 0.55 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) 0.50 GFF5246 Threonine dehydratase biosynthetic (EC 4.3.1.19) low > 127
Shewanella oneidensis MR-1 0.55 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.57 SO4344 ilvA threonine dehydratase (NCBI ptt file) 0.85 70
Marinobacter adhaerens HP15 0.54 HP15_457 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.53 HP15_3213 threonine dehydratase biosynthetic 0.70 47
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS30660 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.46 RR42_RS02315 threonine dehydratase low > 128
Shewanella amazonensis SB2B 0.53 Sama_2627 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.57 Sama_3278 threonine dehydratase (RefSeq) 0.94 42
Variovorax sp. OAS795 0.52 ABID97_RS19395 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.50 ABID97_RS07000 threonine ammonia-lyase, biosynthetic low > 91
Burkholderia phytofirmans PsJN 0.52 BPHYT_RS26655 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.49 BPHYT_RS11065 threonine dehydratase
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.49 ABZR86_RS15925 threonine ammonia-lyase, biosynthetic low > 74
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.45 LRK54_RS10300 threonine ammonia-lyase, biosynthetic low > 59
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.45 LRK55_RS09940 threonine ammonia-lyase, biosynthetic low > 63

Not shown: 12 genomes with orthologs for ECD_03708 only; 14 genomes with orthologs for ECD_03650 only