Conservation of cofitness between ECD_02445 and ECD_00413 in Escherichia coli BL21

56 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_02445 regulatory protein P-II for glutamine synthetase 1.0 ECD_00413 multidrug efflux system protein low > 61
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01154 Nitrogen regulatory protein P-II 1 1.00 OHPLBJKB_03212 Multidrug efflux pump subunit AcrB low > 73
Escherichia coli Nissle 1917 1.00 ECOLIN_RS14450 nitrogen regulatory protein P-II 1.00 ECOLIN_RS02750 efflux RND transporter permease AcrB — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 1.00 GFF2454 Nitrogen regulatory protein P-II 0.94 GFF4379 RND efflux system, inner membrane transporter CmeB low > 78
Escherichia coli BW25113 1.00 b2553 glnB regulatory protein P-II for glutamine synthetase (NCBI) 1.00 b0462 acrB multidrug efflux system protein (NCBI) 0.28 49
Escherichia coli ECRC62 1.00 BNILDI_11975 glnB nitrogen regulatory protein P-II 1.00 BNILDI_22555 acrB efflux RND transporter permease AcrB low > 75
Escherichia coli ECRC99 1.00 KEDOAH_06720 glnB nitrogen regulatory protein P-II 1.00 KEDOAH_19760 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECOR27 1.00 NOLOHH_13175 glnB nitrogen regulatory protein P-II 1.00 NOLOHH_01140 acrB efflux RND transporter permease AcrB low > 75
Escherichia coli ECRC102 1.00 NIAGMN_19270 glnB nitrogen regulatory protein P-II 1.00 NIAGMN_06260 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECRC101 1.00 MCAODC_12030 glnB nitrogen regulatory protein P-II 1.00 MCAODC_27430 acrB efflux RND transporter permease AcrB low > 87
Escherichia fergusonii Becca 1.00 EFB2_01343 Nitrogen regulatory protein P-II 1 1.00 EFB2_03596 Multidrug efflux pump subunit AcrB low > 86
Escherichia coli ECRC100 1.00 OKFHMN_21500 glnB nitrogen regulatory protein P-II 1.00 OKFHMN_08205 acrB efflux RND transporter permease AcrB low > 80
Escherichia coli ECOR38 1.00 HEPCGN_20645 glnB nitrogen regulatory protein P-II 1.00 HEPCGN_06820 acrB efflux RND transporter permease AcrB low > 87
Enterobacter sp. TBS_079 0.99 MPMX20_03422 Nitrogen regulatory protein P-II 0.92 MPMX20_01064 Multidrug efflux pump subunit AcrB low > 85
Enterobacter asburiae PDN3 0.99 EX28DRAFT_0097 nitrogen regulatory protein P-II family 0.92 EX28DRAFT_2496 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 76
Klebsiella michiganensis M5al 0.99 BWI76_RS21245 nitrogen regulatory protein P-II 0.91 BWI76_RS06775 multidrug efflux RND transporter permease subunit low > 92
Dickeya dadantii 3937 0.97 DDA3937_RS15635 nitrogen regulatory protein P-II 0.78 DDA3937_RS05735 multidrug efflux RND transporter permease subunit low > 74
Dickeya dianthicola 67-19 0.96 HGI48_RS15730 nitrogen regulatory protein P-II 0.77 HGI48_RS05790 multidrug efflux RND transporter permease subunit low > 71
Erwinia tracheiphila SCR3 0.96 LU632_RS17925 glnB nitrogen regulatory protein P-II 0.82 LU632_RS18185 efflux RND transporter permease subunit — —
Dickeya dianthicola ME23 0.96 DZA65_RS16810 nitrogen regulatory protein P-II 0.77 DZA65_RS06115 multidrug efflux RND transporter permease subunit low > 75
Pectobacterium carotovorum WPP14 0.95 HER17_RS05930 nitrogen regulatory protein P-II 0.80 HER17_RS15740 multidrug efflux RND transporter permease subunit low > 75
Serratia liquefaciens MT49 0.95 IAI46_19450 nitrogen regulatory protein P-II 0.80 IAI46_05185 multidrug efflux RND transporter permease subunit SdeY low > 86
Pantoea sp. MT58 0.95 IAI47_04950 nitrogen regulatory protein P-II 0.80 IAI47_14515 multidrug efflux RND transporter permease subunit low > 76
Rahnella sp. WP5 0.94 EX31_RS20610 nitrogen regulatory protein P-II 0.85 EX31_RS22470 multidrug efflux RND transporter permease subunit low > 89
Shewanella oneidensis MR-1 0.85 SO3519 glnB-2 nitrogen regulatory protein P-II 1 (NCBI ptt file) 0.66 SO4692 AcrB/AcrD/AcrF family protein (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.85 Shewana3_3124 nitrogen regulatory protein P-II (RefSeq) 0.66 Shewana3_4045 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) low > 73
Shewanella amazonensis SB2B 0.84 Sama_0935 nitrogen regulatory protein P-II (RefSeq) 0.67 Sama_3554 AcrB/AcrD/AcrF family protein (RefSeq) low > 62
Shewanella loihica PV-4 0.83 Shew_1110 nitrogen regulatory protein P-II (RefSeq) 0.65 Shew_0032 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) low > 60
Paraburkholderia graminis OAS925 0.82 ABIE53_001346 nitrogen regulatory protein P-II 1 0.66 ABIE53_003408 multidrug efflux pump low > 113
Burkholderia phytofirmans PsJN 0.82 BPHYT_RS05485 nitrogen regulatory protein P-II 1 0.67 BPHYT_RS16170 multidrug efflux RND transporter permease subunit — —
Paraburkholderia bryophila 376MFSha3.1 0.82 H281DRAFT_00219 nitrogen regulatory protein P-II family 0.67 H281DRAFT_04170 multidrug efflux pump low > 103
Paraburkholderia sabiae LMG 24235 0.82 QEN71_RS24890 P-II family nitrogen regulator 0.68 QEN71_RS02525 efflux RND transporter permease subunit low > 153
Cupriavidus basilensis FW507-4G11 0.81 RR42_RS04300 nitrogen regulatory protein P-II 1 0.65 RR42_RS32420 multidrug efflux RND transporter permease subunit low > 128
Ralstonia solanacearum PSI07 0.80 RPSI07_RS13170 nitrogen regulatory protein P-II 1 0.65 RPSI07_RS03390 multidrug efflux RND transporter permease subunit — —
Ralstonia solanacearum GMI1000 0.80 RS_RS11770 nitrogen regulatory protein P-II 1 0.64 RS_RS21030 multidrug efflux RND transporter permease subunit low > 80
Ralstonia solanacearum UW163 0.79 UW163_RS09490 nitrogen regulatory protein P-II 1 0.64 UW163_RS19380 multidrug efflux RND transporter permease subunit — —
Ralstonia solanacearum IBSBF1503 0.79 RALBFv3_RS04180 nitrogen regulatory protein P-II 1 0.64 RALBFv3_RS19795 multidrug efflux RND transporter permease subunit low > 76
Rhodopseudomonas palustris CGA009 0.76 TX73_015385 P-II family nitrogen regulator 0.58 TX73_012255 efflux RND transporter permease subunit — —
Rhodospirillum rubrum S1H 0.75 Rru_A1130 Nitrogen regulatory protein P-II (GlnB, GlnK) (NCBI) 0.64 Rru_A2051 Hydrophobe/amphiphile efflux-1 HAE1 (NCBI) low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.74 A4249_RS05675 P-II family nitrogen regulator 0.36 A4249_RS09925 multidrug efflux RND transporter permease subunit — —
Sphingomonas koreensis DSMZ 15582 0.74 Ga0059261_3385 nitrogen regulatory protein P-II family 0.52 Ga0059261_0559 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family — —
Rhizobium sp. OAE497 0.74 ABIE40_RS09340 P-II family nitrogen regulator 0.61 ABIE40_RS24225 efflux RND transporter permease subunit — —
Caulobacter crescentus NA1000 Δfur 0.73 CCNA_02046 nitrogen regulatory protein P-II 0.64 CCNA_00850 cation/multidrug efflux pump acrB2 — —
Caulobacter crescentus NA1000 0.73 CCNA_02046 nitrogen regulatory protein P-II 0.64 CCNA_00850 cation/multidrug efflux pump acrB2 — —
Xanthomonas campestris pv. campestris strain 8004 0.73 Xcc-8004.4913.1 Nitrogen regulatory protein P-II 0.64 Xcc-8004.1794.1 RND efflux system, inner membrane transporter CmeB low > 74
Agrobacterium fabrum C58 0.73 Atu1769 nitrogen regulatory protein PII 0.55 Atu2551 RND multidrug efflux transporter — —
Azospirillum brasilense Sp245 0.73 AZOBR_RS07100 nitrogen regulatory protein P-II 1 0.69 AZOBR_RS30185 multidrug transporter — —
Sinorhizobium meliloti 1021 0.73 SMc00947 nitrogen regulatory protein PII 0.52 SMc02867 multidrug-efflux system transmembrane protein — —
Azospirillum sp. SherDot2 0.73 MPMX19_01554 Nitrogen regulatory protein P-II 0.68 MPMX19_05884 Multidrug efflux pump subunit AcrB — —
Castellaniella sp019104865 MT123 0.72 ABCV34_RS03065 P-II family nitrogen regulator 0.49 ABCV34_RS04225 efflux RND transporter permease subunit low > 48
Herbaspirillum seropedicae SmR1 0.71 HSERO_RS09460 nitrogen regulatory protein P-II 1 0.63 HSERO_RS06815 multidrug transporter — —
Desulfovibrio vulgaris Hildenborough JW710 0.66 DVU1232 glnB-1 nitrogen regulatory protein P-II (TIGR) 0.66 DVU2816 multidrug resistance protein (TIGR) low > 55
Phocaeicola dorei CL03T12C01 0.40 ABI39_RS14280 P-II family nitrogen regulator 0.36 ABI39_RS01690 multidrug efflux RND transporter permease subunit low > 72
Bacteroides ovatus ATCC 8483 0.39 BACOVA_03765 nitrogen regulatory protein P-II 0.35 BACOVA_02607 RND transporter, HAE1 family low > 94
Bacteroides thetaiotaomicron VPI-5482 0.39 BT0545 nitrogen regulatory protein P-II (NCBI ptt file) 0.34 BT0886 putative cation efflux pump (NCBI ptt file) low > 81
Phocaeicola vulgatus CL09T03C04 0.39 HMPREF1058_RS06900 P-II family nitrogen regulator 0.36 HMPREF1058_RS02440 multidrug efflux RND transporter permease subunit low > 67
Pontibacter actiniarum KMM 6156, DSM 19842 0.26 CA264_21345 transcriptional regulator 0.36 CA264_03655 multidrug efflux RND transporter permease subunit low > 74

Not shown: 22 genomes with orthologs for ECD_02445 only; 18 genomes with orthologs for ECD_00413 only