| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_06990 | | QacE family quaternary ammonium compound efflux SMR transporter | 1.0 | CSW01_18815 | | AraC family transcriptional regulator | 0.65 | 2 |
| Pseudomonas sp. BP01 | 0.65 | JOY50_RS28055 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.34 | JOY50_RS17460 | | helix-turn-helix transcriptional regulator | low | > 84 |
| Pseudomonas sp. SVBP6 | 0.65 | COO64_RS07120 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.37 | COO64_RS18105 | | helix-turn-helix transcriptional regulator | low | > 93 |
| Pseudomonas fluorescens FW300-N2E3 | 0.65 | AO353_02525 | | molecular chaperone | 0.36 | AO353_13450 | | AraC family transcriptional regulator | low | > 101 |
| Pseudomonas fluorescens FW300-N1B4 | 0.64 | Pf1N1B4_3729 | | Quaternary ammonium compound-resistance protein SugE | 0.37 | Pf1N1B4_1362 | | Transcriptional regulator, AraC family | low | > 87 |
| Pseudomonas putida KT2440 | 0.64 | PP_1701 | | transporter | 0.34 | PP_4852 | | Transcriptional regulator, AraC family | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.64 | PfGW456L13_4218 | | Quaternary ammonium compound-resistance protein SugE | 0.36 | PfGW456L13_100 | | Transcriptional regulator, AraC family | low | > 87 |
| Pseudomonas fluorescens FW300-N2E2 | 0.63 | Pf6N2E2_5766 | | Quaternary ammonium compound-resistance protein SugE | 0.34 | Pf6N2E2_475 | | Transcriptional regulator, AraC family | 0.24 | 6 |
| Pseudomonas fluorescens FW300-N2C3 | 0.63 | AO356_19255 | | molecular chaperone | 0.34 | AO356_22960 | | AraC family transcriptional regulator | low | > 104 |
| Pseudomonas sp. RS175 | 0.63 | PFR28_03184 | | Guanidinium exporter | 0.24 | PFR28_05241 | | HTH-type transcriptional regulator NimR | low | > 88 |
| Pseudomonas orientalis W4I3 | 0.63 | QF045_RS11900 | | quaternary ammonium compound efflux SMR transporter SugE | 0.39 | QF045_RS05795 | | helix-turn-helix transcriptional regulator | low | > 93 |
| Pseudomonas sp. DMC3 | 0.63 | GFF2572 | | Guanidinium exporter | 0.38 | GFF3270 | | HTH-type transcriptional regulator NimR | low | > 89 |
| Pseudomonas aeruginosa PUPa3 | 0.62 | DQ20_RS40465 | sugE;go_component=membrane|0016020||IEA;go_function=transmembrane | quaternary ammonium compound efflux SMR transporter SugE | 0.41 | DQ20_RS57520 | | helix-turn-helix transcriptional regulator | low | > 101 |
| Pseudomonas aeruginosa MRSN321 | 0.62 | DY961_RS00570 | sugE;go_component=membrane|0016020||IEA;go_function=transmembrane | quaternary ammonium compound efflux SMR transporter SugE | 0.41 | DY961_RS25065 | | helix-turn-helix transcriptional regulator | low | > 100 |
| Pseudomonas segetis P6 | 0.62 | MPMX49_01733 | | Guanidinium exporter | 0.27 | MPMX49_00356 | | HTH-type transcriptional regulator NimR | low | > 75 |
| Pseudomonas aeruginosa PA14 | 0.62 | IKLFDK_16715 | | quaternary ammonium compound efflux SMR transporter SugE | 0.41 | IKLFDK_02670 | | AraC family transcriptional regulator | low | > 98 |
| Pseudomonas fluorescens SBW25-INTG | 0.62 | PFLU_RS09245 | | quaternary ammonium compound efflux SMR transporter SugE | 0.39 | PFLU_RS02820 | | AraC family transcriptional regulator | low | > 109 |
| Pseudomonas simiae WCS417 | 0.62 | PS417_09235 | | molecular chaperone | 0.39 | PS417_02760 | | AraC family transcriptional regulator | low | > 88 |
| Pseudomonas lactucae CFBP13502 | 0.62 | GEMAOFIL_01970 | | Guanidinium exporter | 0.29 | GEMAOFIL_03519 | | HTH-type transcriptional regulator NimR | low | > 96 |
| Pseudomonas fluorescens SBW25 | 0.62 | PFLU_RS09245 | | quaternary ammonium compound efflux SMR transporter SugE | 0.39 | PFLU_RS02820 | | AraC family transcriptional regulator | low | > 109 |
| Enterobacter asburiae PDN3 | 0.59 | EX28DRAFT_3348 | | Membrane transporters of cations and cationic drugs | 0.23 | EX28DRAFT_1780 | | AraC-type DNA-binding domain-containing proteins | low | > 76 |
| Enterobacter sp. TBS_079 | 0.58 | MPMX20_00430 | | Guanidinium exporter | 0.24 | MPMX20_01835 | | HTH-type transcriptional regulator NimR | low | > 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.58 | GFF2001 | | Quaternary ammonium compound-resistance protein SugE | 0.19 | GFF3466 | | Transcriptional regulator, AraC family | low | > 78 |
| Klebsiella michiganensis M5al | 0.58 | BWI76_RS02430 | | multidrug transporter | 0.24 | BWI76_RS11455 | | AraC family transcriptional regulator | low | > 92 |
| Azospirillum brasilense Sp245 | 0.57 | AZOBR_RS09160 | | multidrug transporter | 0.23 | AZOBR_RS31815 | | AraC family transcriptional regulator | low | > 97 |
| Rhodopseudomonas palustris CGA009 | 0.56 | TX73_011815 | | quaternary ammonium compound efflux SMR transporter SugE | 0.23 | TX73_016840 | | helix-turn-helix transcriptional regulator | low | > 86 |
| Serratia liquefaciens MT49 | 0.56 | IAI46_01525 | | quaternary ammonium compound efflux SMR transporter SugE | 0.41 | IAI46_17855 | | helix-turn-helix transcriptional regulator | low | > 87 |
| Desulfovibrio vulgaris Miyazaki F | 0.55 | DvMF_3195 | | small multidrug resistance protein (RefSeq) | 0.24 | DvMF_0808 | | transcriptional regulator, AraC family (RefSeq) | low | > 51 |
| Klebsiella pneumoniae MKP103 | 0.55 | KDGMDA_10925 | | quaternary ammonium compound efflux SMR transporter SugE | 0.23 | KDGMDA_19080 | | AraC family transcriptional regulator | low | > 95 |
| Escherichia coli ECRC102 | 0.55 | NIAGMN_10220 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.21 | NIAGMN_01385 | nimR | DNA-binding transcriptional regulator NimR | low | > 80 |
| Escherichia coli ECOR27 | 0.55 | NOLOHH_04635 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.22 | NOLOHH_17210 | nimR | DNA-binding transcriptional regulator NimR | low | > 76 |
| Escherichia fergusonii Becca | 0.55 | EFB2_04385 | | Guanidinium exporter | 0.22 | EFB2_02205 | | HTH-type transcriptional regulator NimR | low | > 86 |
| Escherichia coli ECRC100 | 0.55 | OKFHMN_12375 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.21 | OKFHMN_26680 | nimR | DNA-binding transcriptional regulator NimR | low | > 79 |
| Escherichia coli ECRC99 | 0.55 | KEDOAH_15790 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.21 | KEDOAH_01430 | nimR | DNA-binding transcriptional regulator NimR | — | — |
| Escherichia coli ECRC62 | 0.55 | BNILDI_06855 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.22 | BNILDI_15995 | nimR | DNA-binding transcriptional regulator NimR | low | > 75 |
| Escherichia coli ECRC101 | 0.55 | MCAODC_02885 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.21 | MCAODC_18730 | nimR | DNA-binding transcriptional regulator NimR | low | > 87 |
| Azospirillum sp. SherDot2 | 0.55 | MPMX19_00878 | | Guanidinium exporter | 0.22 | MPMX19_04533 | | HTH-type transcriptional regulator NimR | low | > 112 |
| Escherichia coli ECOR38 | 0.55 | HEPCGN_10600 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.22 | HEPCGN_05070 | nimR | DNA-binding transcriptional regulator NimR | low | > 88 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.55 | OHPLBJKB_03892 | | Quaternary ammonium compound-resistance protein SugE | 0.22 | OHPLBJKB_01943 | | HTH-type transcriptional regulator NimR | low | > 74 |
| Escherichia coli BL21 | 0.55 | ECD_04020 | | multidrug efflux system protein | 0.21 | ECD_01759 | | putative DNA-binding transcriptional regulator | — | — |
| Escherichia coli ECRC98 | 0.55 | JDDGAC_16010 | sugE | quaternary ammonium compound efflux SMR transporter SugE | 0.21 | JDDGAC_01255 | nimR | DNA-binding transcriptional regulator NimR | low | > 87 |
| Escherichia coli Nissle 1917 | 0.55 | ECOLIN_RS24100 | | quaternary ammonium compound efflux SMR transporter SugE | 0.22 | ECOLIN_RS09975 | | DNA-binding transcriptional regulator NimR | low | > 55 |
| Escherichia coli BW25113 | 0.55 | b4148 | sugE | suppresses groEL, may be chaperone (VIMSS) | 0.22 | b1790 | yeaM | predicted DNA-binding transcriptional regulator (NCBI) | low | > 76 |
| Variovorax sp. OAS795 | 0.54 | ABID97_RS10520 | | quaternary ammonium compound efflux SMR transporter SugE | 0.20 | ABID97_RS28450 | | helix-turn-helix transcriptional regulator | low | > 91 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.52 | H281DRAFT_04535 | | quaternary ammonium compound-resistance protein SugE | 0.22 | H281DRAFT_06000 | | transcriptional regulator, AraC family | low | > 103 |
| Shewanella sp. ANA-3 | 0.51 | Shewana3_1676 | | small multidrug resistance protein (RefSeq) | 0.55 | Shewana3_0925 | | AraC family transcriptional regulator (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.51 | SO1901 | sugE | sugE protein (NCBI ptt file) | 0.54 | SO1092 | | transcriptional regulator, AraC/XylS family (NCBI ptt file) | low | > 76 |
| Rhodospirillum rubrum S1H | 0.50 | Rru_A0272 | | Small multidrug resistance protein (NCBI) | 0.24 | Rru_A2490 | | Transcriptional Regulator, AraC family (NCBI) | — | — |
| Paraburkholderia graminis OAS925 | 0.50 | ABIE53_001558 | | quaternary ammonium compound-resistance protein SugE | 0.22 | ABIE53_001863 | | AraC-like DNA-binding protein | low | > 113 |
| Acinetobacter baumannii LAC-4 | 0.47 | RR41_RS15715 | | multidrug efflux SMR transporter | 0.33 | RR41_RS02400 | | helix-turn-helix transcriptional regulator | low | > 55 |
| Rahnella sp. WP5 | 0.47 | EX31_RS00585 | | multidrug efflux SMR transporter | 0.46 | EX31_RS19615 | | helix-turn-helix transcriptional regulator | low | > 89 |
| Pseudomonas stutzeri RCH2 | 0.46 | Psest_0857 | | Membrane transporters of cations and cationic drugs | 0.25 | Psest_4208 | | AraC-type DNA-binding domain-containing proteins | low | > 67 |
| Sphingomonas koreensis DSMZ 15582 | 0.45 | Ga0059261_0749 | | Membrane transporters of cations and cationic drugs | 0.22 | Ga0059261_2138 | | transcriptional regulator, AraC family | low | > 68 |
| Acinetobacter radioresistens SK82 | 0.45 | MPMX26_02568 | | Guanidinium exporter | 0.23 | MPMX26_00111 | | HTH-type transcriptional regulator NimR | — | — |
| Ralstonia sp. UNC404CL21Col | 0.41 | ABZR87_RS21585 | | multidrug efflux SMR transporter | 0.35 | ABZR87_RS23255 | | helix-turn-helix transcriptional regulator | low | > 80 |
| Dickeya dianthicola 67-19 | 0.34 | HGI48_RS06305 | | multidrug efflux SMR transporter | 0.17 | HGI48_RS03820 | | helix-turn-helix domain-containing protein | low | > 71 |
| Pseudomonas syringae pv. syringae B728a | 0.33 | Psyr_0541 | | Small multidrug resistance protein | 0.24 | Psyr_0649 | | transcriptional regulator, AraC family | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.33 | Psyr_0541 | | Small multidrug resistance protein | 0.24 | Psyr_0649 | | transcriptional regulator, AraC family | low | > 86 |
| Dickeya dianthicola ME23 | 0.32 | DZA65_RS06650 | | multidrug transporter | 0.16 | DZA65_RS08670 | | helix-turn-helix transcriptional regulator | low | > 75 |
| Pantoea agglomerans CFBP13505 P0401 | 0.31 | PagCFBP13505_RS02465 | | multidrug/spermidine efflux SMR transporter subunit MdtI | 0.39 | PagCFBP13505_RS00185 | | helix-turn-helix transcriptional regulator | low | > 74 |
| Variovorax sp. SCN45 | 0.30 | GFF2129 | | small multidrug resistance family (SMR) protein | 0.38 | GFF4545 | | Transcriptional regulator, AraC family | low | > 127 |
| Pantoea sp. MT58 | 0.28 | IAI47_08635 | | multidrug/spermidine efflux SMR transporter subunit MdtI | 0.19 | IAI47_10240 | | helix-turn-helix transcriptional regulator | low | > 76 |
| Erwinia amylovora T8 | 0.28 | OLJFJH_08005 | | multidrug/spermidine efflux SMR transporter subunit MdtJ | 0.45 | OLJFJH_11225 | | AraC family transcriptional regulator | low | > 58 |
| Herbaspirillum seropedicae SmR1 | 0.28 | HSERO_RS23145 | | multidrug transporter | 0.23 | HSERO_RS21185 | | transcriptional regulator | low | > 78 |
| Cupriavidus basilensis FW507-4G11 | 0.27 | RR42_RS14705 | | multidrug transporter | 0.36 | RR42_RS35075 | | AraC family transcriptional regulator | low | > 128 |
Not shown: 35 genomes with orthologs for CSW01_06990 only; 6 genomes with orthologs for CSW01_18815 only