Conservation of cofitness between CSW01_16895 and CSW01_18075 in Vibrio cholerae E7946 ATCC 55056

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_16895 DNA-binding response regulator 1.0 CSW01_18075 nucleotide sugar dehydrogenase 0.46 12
Erwinia amylovora T8 0.49 OLJFJH_17030 two-component system response regulator KdpE 0.19 OLJFJH_13295 UDP-glucose 6-dehydrogenase — —
Enterobacter sp. TBS_079 0.49 MPMX20_01337 KDP operon transcriptional regulatory protein KdpE 0.75 MPMX20_03011 UDP-glucose 6-dehydrogenase — —
Enterobacter asburiae PDN3 0.49 EX28DRAFT_2284 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 0.74 EX28DRAFT_0530 nucleotide sugar dehydrogenase — —
Dechlorosoma suillum PS 0.48 Dsui_0271 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain 0.21 Dsui_1947 nucleotide sugar dehydrogenase low > 51
Erwinia tracheiphila HP pepo 2.2 0.48 IJEDHG_02220 kdpE two-component system response regulator KdpE 0.18 IJEDHG_22700 ugd UDP-glucose 6-dehydrogenase — —
Erwinia tracheiphila SCR3 0.48 LU632_RS16165 kdpE two-component system response regulator KdpE 0.18 LU632_RS12915 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Pseudomonas fluorescens FW300-N1B4 0.48 Pf1N1B4_311 sensor histidine kinase 0.21 Pf1N1B4_5884 UDP-glucose dehydrogenase (EC 1.1.1.22) low > 87
Pseudomonas lactucae CFBP13502 0.47 GEMAOFIL_01790 KDP operon transcriptional regulatory protein KdpE 0.18 GEMAOFIL_02974 UDP-glucose 6-dehydrogenase low > 96
Pseudomonas sp. DMC3 0.47 GFF4642 Transcriptional regulatory protein KdpE 0.21 GFF963 UDP-glucose 6-dehydrogenase low > 89
Pseudomonas sp. S08-1 0.47 OH686_01885 DNA-binding response regulator KdpE 0.68 OH686_14205 UDP-glucose 6-dehydrogenase low > 80
Pseudomonas fluorescens SBW25 0.47 PFLU_RS08245 response regulator 0.20 PFLU_RS17930 UDP-glucose/GDP-mannose dehydrogenase family protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS08245 response regulator 0.20 PFLU_RS17930 UDP-glucose/GDP-mannose dehydrogenase family protein low > 109
Dyella japonica UNC79MFTsu3.2 0.47 ABZR86_RS13215 response regulator 0.21 ABZR86_RS07210 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Pseudomonas sp. BP01 0.47 JOY50_RS07160 response regulator 0.20 JOY50_RS24545 UDP-glucose/GDP-mannose dehydrogenase family protein low > 84
Pseudomonas simiae WCS417 0.47 PS417_08305 transcriptional regulator 0.18 PS417_13820 UDP-glucose 6-dehydrogenase low > 88
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_03295 transcriptional regulator 0.21 AO356_01140 UDP-glucose 6-dehydrogenase low > 104
Pseudomonas sp. SVBP6 0.47 COO64_RS09705 response regulator 0.21 COO64_RS21115 UDP-glucose/GDP-mannose dehydrogenase family protein 0.29 82
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_2490 sensor histidine kinase 0.21 Pf6N2E2_125 UDP-glucose dehydrogenase (EC 1.1.1.22) low > 103
Methylophilus sp. DMC18 0.47 GFF2684 KDP operon transcriptional regulatory protein KdpE 0.74 GFF701 UDP-glucose 6-dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.47 OHPLBJKB_03023 KDP operon transcriptional regulatory protein KdpE 0.73 OHPLBJKB_01664 UDP-glucose 6-dehydrogenase — —
Escherichia coli Nissle 1917 0.47 ECOLIN_RS03750 two-component system response regulator KdpE 0.72 ECOLIN_RS11985 UDP-glucose 6-dehydrogenase — —
Escherichia coli ECRC62 0.47 BNILDI_21465 kdpE two-component system response regulator KdpE 0.72 BNILDI_14700 ugd UDP-glucose 6-dehydrogenase low > 75
Escherichia coli ECOR27 0.47 NOLOHH_23460 kdpE two-component system response regulator KdpE 0.72 NOLOHH_15790 ugd UDP-glucose 6-dehydrogenase low > 76
Escherichia coli ECOR38 0.47 HEPCGN_01155 kdpE two-component system response regulator KdpE 0.72 HEPCGN_03180 ugd UDP-glucose 6-dehydrogenase low > 88
Escherichia fergusonii Becca 0.47 EFB2_03402 KDP operon transcriptional regulatory protein KdpE 0.72 EFB2_01827 UDP-glucose 6-dehydrogenase low > 86
Pseudomonas sp. RS175 0.47 PFR28_00943 KDP operon transcriptional regulatory protein KdpE 0.21 PFR28_02768 UDP-glucose 6-dehydrogenase low > 88
Escherichia coli BW25113 0.47 b0694 kdpE DNA-binding response regulator in two-component regulatory system with KdpD (NCBI) 0.72 b2028 ugd UDP-glucose 6-dehydrogenase (NCBI) low > 76
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_2051 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.19 Psyr_5105 UDP-glucose 6-dehydrogenase low > 86
Variovorax sp. SCN45 0.46 GFF3521 DNA-binding response regulator KdpE 0.19 GFF3562 UDP-glucose 6-dehydrogenase (EC 1.1.1.22) low > 127
Pseudomonas putida KT2440 0.46 PP_4157 two-component system DNA-binding response activator KdpE 0.20 PP_2926 UDP-glucose 6-dehydrogenase low > 96
Escherichia coli BL21 0.46 ECD_00651 response regulator in two-component regulatory system with KdpD 0.72 ECD_01930 UDP-glucose 6-dehydrogenase low > 61
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_2051 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.19 Psyr_5105 UDP-glucose 6-dehydrogenase low > 86
Escherichia coli ECRC102 0.46 NIAGMN_05135 kdpE two-component system response regulator KdpE 0.72 NIAGMN_22420 ugd UDP-glucose 6-dehydrogenase low > 80
Dickeya dadantii 3937 0.46 DDA3937_RS06365 two-component system response regulator KdpE 0.75 DDA3937_RS06790 nucleotide sugar dehydrogenase — —
Pectobacterium carotovorum WPP14 0.46 HER17_RS15050 two-component system response regulator KdpE 0.70 HER17_RS06515 nucleotide sugar dehydrogenase low > 75
Escherichia coli ECRC99 0.46 KEDOAH_20890 kdpE two-component system response regulator KdpE 0.72 KEDOAH_03675 ugd UDP-glucose 6-dehydrogenase — —
Escherichia coli ECRC98 0.46 JDDGAC_10730 kdpE two-component system response regulator KdpE 0.72 JDDGAC_28585 ugd UDP-glucose 6-dehydrogenase low > 87
Escherichia coli ECRC101 0.46 MCAODC_26295 kdpE two-component system response regulator KdpE 0.72 MCAODC_20465 ugd UDP-glucose 6-dehydrogenase low > 87
Escherichia coli ECRC100 0.46 OKFHMN_07080 kdpE two-component system response regulator KdpE 0.72 OKFHMN_24475 ugd UDP-glucose 6-dehydrogenase low > 79
Pantoea sp. MT58 0.46 IAI47_13830 two-component system response regulator KdpE 0.19 IAI47_09035 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Xanthomonas campestris pv. campestris strain 8004 0.46 Xcc-8004.4378.1 sensor histidine kinase 0.21 Xcc-8004.3391.1 hypothetical protein — —
Caulobacter crescentus NA1000 0.46 CCNA_01667 two-component response regulator kdpE 0.22 CCNA_02464 UDP-glucose 6-dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.46 CCNA_01667 two-component response regulator kdpE 0.22 CCNA_02464 UDP-glucose 6-dehydrogenase low > 67
Klebsiella pneumoniae MKP103 0.46 KDGMDA_16625 two-component system response regulator KdpE 0.74 KDGMDA_26170 UDP-glucose 6-dehydrogenase — —
Pantoea agglomerans CFBP13505 P0401 0.46 PagCFBP13505_RS03475 two-component system response regulator KdpE 0.19 PagCFBP13505_RS02875 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.45 GFF4606 sensor histidine kinase 0.73 GFF3904 UDP-glucose 6-dehydrogenase (EC 1.1.1.22) low > 78
Rahnella sp. WP5 0.45 EX31_RS23330 two-component system response regulator KdpE 0.19 EX31_RS10095 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Brevundimonas sp. GW460-12-10-14-LB2 0.45 A4249_RS15625 response regulator 0.20 A4249_RS02200 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Klebsiella michiganensis M5al 0.45 BWI76_RS08300 DNA-binding response regulator 0.74 BWI76_RS19020 UDP-glucose 6-dehydrogenase — —
Dickeya dianthicola ME23 0.45 DZA65_RS06755 two-component system response regulator KdpE 0.75 DZA65_RS07165 nucleotide sugar dehydrogenase — —
Dickeya dianthicola 67-19 0.45 HGI48_RS06410 two-component system response regulator KdpE 0.75 HGI48_RS06825 nucleotide sugar dehydrogenase — —
Mycobacterium tuberculosis H37Rv 0.45 Rv1027c Probable transcriptional regulatory protein KdpE 0.19 Rv0322 Probable UDP-glucose 6-dehydrogenase UdgA (UDP-GLC dehydrogenase) (UDP-GLCDH) (UDPGDH) — —
Ralstonia solanacearum PSI07 0.45 RPSI07_RS09645 two-component system response regulator KdpE 0.18 RPSI07_RS19665 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Ralstonia solanacearum UW163 0.45 UW163_RS06015 two-component system response regulator KdpE 0.18 UW163_RS16005 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS07605 two-component system response regulator KdpE 0.18 RALBFv3_RS13805 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Ralstonia solanacearum GMI1000 0.45 RS_RS15505 two-component system response regulator KdpE 0.18 RS_RS04540 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Lysobacter sp. OAE881 0.44 ABIE51_RS10000 response regulator transcription factor 0.20 ABIE51_RS09065 UDP-glucose/GDP-mannose dehydrogenase family protein low > 62
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS03270 two-component system response regulator KdpE 0.18 ABZR87_RS09495 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.43 GFF4475 sensor histidine kinase 0.19 GFF4731 UDP-glucose dehydrogenase (EC 1.1.1.22) low > 90
Acinetobacter baumannii LAC-4 0.42 RR41_RS06945 response regulator transcription factor 0.12 RR41_RS18535 nucleotide sugar dehydrogenase low > 55
Magnetospirillum magneticum AMB-1 0.42 AMB_RS09660 DNA-binding response regulator 0.22 AMB_RS02980 UDP-glucose/GDP-mannose dehydrogenase family protein — —
Sphingomonas koreensis DSMZ 15582 0.40 Ga0059261_3886 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 0.21 Ga0059261_4043 UDP-glucose dehydrogenase — —
Sphingobium sp. HT1-2 0.39 GFF2987 DNA-binding response regulator KdpE 0.64 GFF4211 UDP-glucose 6-dehydrogenase (EC 1.1.1.22) low > 95
Shewanella sp. ANA-3 0.35 Shewana3_0059 two component transcriptional regulator (RefSeq) 0.74 Shewana3_1387 UDP-glucose/GDP-mannose dehydrogenase (RefSeq) low > 73
Shewanella oneidensis MR-1 0.34 SO0059 kdpE transcriptional regulatory protein KdpE (NCBI ptt file) 0.69 SO4687 ugd UDP-glucose 6-dehydrogenase (NCBI ptt file) low > 76
Alteromonas macleodii MIT1002 0.32 MIT1002_01389 KDP operon transcriptional regulatory protein KdpE 0.72 MIT1002_03556 UDP-glucose 6-dehydrogenase — —
Bacteroides thetaiotaomicron VPI-5482 0.28 BT0732 two-component system response regulator (NCBI ptt file) 0.58 BT0379 UDP-glucose 6-dehydrogenase (NCBI ptt file) — —
Parabacteroides merdae CL09T00C40 0.28 HMPREF1078_RS02085 response regulator transcription factor 0.20 HMPREF1078_RS17435 UDP-glucose/GDP-mannose dehydrogenase family protein low > 61

Not shown: 26 genomes with orthologs for CSW01_16895 only; 17 genomes with orthologs for CSW01_18075 only