Conservation of cofitness between CSW01_09720 and CSW01_13635 in Vibrio cholerae E7946 ATCC 55056

64 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_09720 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 1.0 CSW01_13635 thiol:disulfide interchange protein DsbD 0.79 14
Rahnella sp. WP5 0.69 EX31_RS22835 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.46 EX31_RS08975 protein-disulfide reductase DsbD
Klebsiella michiganensis M5al 0.68 BWI76_RS07100 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.47 BWI76_RS02315 protein-disulfide reductase DsbD
Serratia liquefaciens MT49 0.68 IAI46_05400 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.45 IAI46_01465 protein-disulfide reductase DsbD
Klebsiella pneumoniae MKP103 0.68 KDGMDA_15035 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.45 KDGMDA_10805 Thiol:disulfide interchange protein DsbD
Klebsiella pneumoniae MRSN742743 0.68 KFA93_RS03235 folD;go_function=methylenetetrahydrofolate bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.46 KFA93_RS21290 protein-disulfide reductase DsbD
Enterobacter asburiae PDN3 0.68 EX28DRAFT_2449 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.46 EX28DRAFT_3333 Thiol:disulfide interchange protein
Pantoea sp. MT58 0.68 IAI47_14320 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.43 IAI47_17335 protein-disulfide reductase DsbD
Shewanella amazonensis SB2B 0.68 Sama_1222 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.42 Sama_0538 dipZ thiol:disulfide interchange protein precursor (RefSeq)
Enterobacter sp. TBS_079 0.68 MPMX20_01107 Bifunctional protein FolD protein 0.45 MPMX20_00416 Thiol:disulfide interchange protein DsbD
Shewanella sp. ANA-3 0.68 Shewana3_2663 methenyltetrahydrofolate cyclohydrolase (RefSeq) 0.43 Shewana3_3576 dipZ thiol:disulfide interchange protein precursor (RefSeq)
Escherichia fergusonii Becca 0.68 EFB2_03532 Bifunctional protein FolD protein 0.47 EFB2_04399 Thiol:disulfide interchange protein DsbD
Escherichia coli ECOR27 0.68 NOLOHH_00795 Bifunctional protein FolD 0.47 NOLOHH_04715 dsbD protein-disulfide reductase DsbD
Escherichia coli BW25113 0.68 b0529 folD bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (NCBI) 0.47 b4136 dipZ thiol:disulfide interchange protein precursor (NCBI)
Escherichia coli HS(pFamp)R (ATCC 700891) 0.68 OHPLBJKB_03152 Bifunctional protein FolD protein 0.47 OHPLBJKB_03907 Thiol:disulfide interchange protein DsbD
Escherichia coli BL21 0.68 ECD_00479 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 0.47 ECD_04006 thiol:disulfide interchange protein and activator of DsbC
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.68 GFF4447 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.46 GFF2016 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)
Escherichia coli ECRC101 0.68 MCAODC_27025 Bifunctional protein FolD 0.46 MCAODC_02960 dsbD protein-disulfide reductase DsbD
Escherichia coli Nissle 1917 0.68 ECOLIN_RS03065 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 ECOLIN_RS24030 protein-disulfide reductase DsbD
Escherichia coli ECRC100 0.68 OKFHMN_07805 Bifunctional protein FolD 0.47 OKFHMN_12450 dsbD protein-disulfide reductase DsbD
Pantoea agglomerans CFBP13505 P0401 0.68 PagCFBP13516_RS14565 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.44 PagCFBP13516_RS17630 protein-disulfide reductase DsbD
Escherichia coli ECRC99 0.68 KEDOAH_20165 Bifunctional protein FolD 0.47 KEDOAH_15715 dsbD protein-disulfide reductase DsbD
Escherichia coli ECRC98 0.68 JDDGAC_11455 Bifunctional protein FolD 0.47 JDDGAC_16085 dsbD protein-disulfide reductase DsbD
Escherichia coli ECRC102 0.68 NIAGMN_05860 Bifunctional protein FolD 0.47 NIAGMN_10295 dsbD protein-disulfide reductase DsbD
Escherichia coli ECOR38 0.67 HEPCGN_06445 Bifunctional protein FolD 0.46 HEPCGN_10675 dsbD protein-disulfide reductase DsbD
Escherichia coli ECRC62 0.67 BNILDI_22225 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 BNILDI_06775 dsbD protein-disulfide reductase DsbD
Erwinia amylovora T8 0.67 OLJFJH_17600 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 OLJFJH_02625 protein-disulfide reductase DsbD
Pectobacterium carotovorum WPP14 0.67 HER17_RS06505 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.47 HER17_RS18850 protein-disulfide reductase DsbD
Shewanella loihica PV-4 0.67 Shew_2510 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) 0.42 Shew_3266 dipZ thiol:disulfide interchange protein precursor (RefSeq)
Dickeya dadantii 3937 0.67 DDA3937_RS15075 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.43 DDA3937_RS02705 protein-disulfide reductase DsbD
Alteromonas macleodii MIT1002 0.66 MIT1002_02770 hypothetical protein 0.38 MIT1002_03939 Thiol:disulfide interchange protein DsbD precursor
Erwinia tracheiphila SCR3 0.66 LU632_RS15195 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.40 LU632_RS01840 protein-disulfide reductase DsbD
Shewanella oneidensis MR-1 0.66 SO1792 folD methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (NCBI ptt file) 0.44 SO0696 dsbD thiol:disulfide interchange protein DsbD (NCBI ptt file)
Dickeya dianthicola 67-19 0.66 HGI48_RS15155 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 HGI48_RS02680 protein-disulfide reductase DsbD
Dickeya dianthicola ME23 0.66 DZA65_RS15960 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.42 DZA65_RS02835 protein-disulfide reductase DsbD
Erwinia tracheiphila HP pepo 2.2 0.66 IJEDHG_00975 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.40 IJEDHG_07065 Thiol:disulfide interchange protein DsbD
Pseudomonas simiae WCS417 0.62 PS417_17265 methenyltetrahydrofolate cyclohydrolase 0.26 PS417_19525 thiol:disulfide interchange protein
Pseudomonas orientalis W4I3 0.62 QF045_RS18930 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.26 QF045_RS21665 protein-disulfide reductase DsbD
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_2550 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.28 PfGW456L13_2298 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_01775 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.28 AO356_02870 thiol:disulfide interchange protein
Marinobacter adhaerens HP15 0.61 HP15_2187 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.30 HP15_2101 membrane protein containing cytochrome c assembly protein, transmembrane region domain
Pseudomonas sp. RS175 0.61 PFR28_01223 Bifunctional protein FolD protein 0.27 PFR28_01029 Thiol:disulfide interchange protein DsbD
Pseudomonas fluorescens FW300-N2E2 0.61 Pf6N2E2_2221 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.28 Pf6N2E2_2398 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)
Pseudomonas fluorescens SBW25 0.61 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.25 PFLU_RS21490 protein-disulfide reductase DsbD
Pseudomonas lactucae CFBP13502 0.61 GEMAOFIL_03749 Bifunctional protein FolD protein 0.25 GEMAOFIL_04105 Thiol:disulfide interchange protein DsbD
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.25 PFLU_RS21490 protein-disulfide reductase DsbD
Pseudomonas putida KT2440 0.61 PP_2265 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.25 PP_0561 thiol/disulfide interchange protein 1
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_3943 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) 0.27 Pf1N1B4_210 Cytochrome c-type biogenesis protein DsbD, protein-disulfide reductase (EC 1.8.1.8)
Pseudomonas sp. BP01 0.61 JOY50_RS25950 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.26 JOY50_RS23140 protein-disulfide reductase DsbD
Pseudomonas protegens RBAN4 0.61 FABNJH_20635 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.27 FABNJH_21580 dsbD Thiol:disulfide interchange protein DsbD
Pseudomonas sp. DMC3 0.61 GFF1441 Bifunctional protein FolD protein 0.29 GFF4549 Thiol:disulfide interchange protein DsbD
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_20145 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase 0.25 AO353_19365 thiol:disulfide interchange protein
Pseudomonas segetis P6 0.60 ACVTMO_RS11215 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.26 ACVTMO_RS20330 protein-disulfide reductase DsbD
Pseudomonas stutzeri RCH2 0.58 Psest_2301 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 0.27 Psest_1603 Thiol:disulfide interchange protein
Kangiella aquimarina DSM 16071 0.57 B158DRAFT_1028 methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)/5,10-methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) 0.32 B158DRAFT_0153 Thiol:disulfide interchange protein
Castellaniella sp019104865 MT123 0.48 ABCV34_RS04175 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.27 ABCV34_RS03205 protein-disulfide reductase DsbD
Herbaspirillum seropedicae SmR1 0.46 HSERO_RS07295 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 0.29 HSERO_RS00715 thiol:disulfide interchange protein
Cupriavidus basilensis FW507-4G11 0.46 RR42_RS07345 methenyltetrahydrofolate cyclohydrolase 0.29 RR42_RS19110 thiol:disulfide interchange protein
Dechlorosoma suillum PS 0.46 Dsui_0093 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase 0.31 Dsui_0718 thiol:disulfide interchange protein
Ralstonia solanacearum PSI07 0.45 RPSI07_RS15800 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.28 RPSI07_RS10195 protein-disulfide reductase DsbD
Ralstonia solanacearum UW163 0.45 UW163_RS14995 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.27 UW163_RS06570 protein-disulfide reductase DsbD
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS01685 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.27 RALBFv3_RS07045 protein-disulfide reductase DsbD
Ralstonia sp. UNC404CL21Col 0.45 ABZR87_RS13485 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.28 ABZR87_RS02695 protein-disulfide reductase DsbD
Ralstonia solanacearum GMI1000 0.45 RS_RS08040 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase 0.27 RS_RS14985 thiol:disulfide interchange protein DsbD
Paraburkholderia graminis OAS925 0.42 ABIE53_002796 methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase 0.26 ABIE53_000167 thiol:disulfide interchange protein DsbD

Not shown: 58 genomes with orthologs for CSW01_09720 only; 1 genomes with orthologs for CSW01_13635 only