Conservation of cofitness between CSW01_02970 and CSW01_12680 in Vibrio cholerae E7946 ATCC 55056

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02970 glutamate--cysteine ligase 1.0 CSW01_12680 cytosol aminopeptidase 0.84 18
Rahnella sp. WP5 0.55 EX31_RS07750 glutamate--cysteine ligase 0.83 EX31_RS04385 leucyl aminopeptidase low > 89
Enterobacter asburiae PDN3 0.55 EX28DRAFT_2774 glutamate-cysteine ligase (EC 6.3.2.2) 0.82 EX28DRAFT_3267 Leucyl aminopeptidase low > 76
Klebsiella pneumoniae MKP103 0.55 KDGMDA_02790 glutamate--cysteine ligase 0.81 KDGMDA_11530 leucyl aminopeptidase low > 95
Enterobacter sp. TBS_079 0.55 MPMX20_03568 Glutamate--cysteine ligase 0.82 MPMX20_04118 Cytosol aminopeptidase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.54 GFF1597 Glutamate--cysteine ligase (EC 6.3.2.2) 0.82 GFF949 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 78
Serratia liquefaciens MT49 0.54 IAI46_03895 glutamate--cysteine ligase 0.83 IAI46_02360 leucyl aminopeptidase 0.46 49
Escherichia coli ECRC98 0.54 JDDGAC_24425 gshA glutamate--cysteine ligase 0.82 JDDGAC_15430 pepA leucyl aminopeptidase 0.43 43
Escherichia coli ECRC101 0.54 MCAODC_11285 gshA glutamate--cysteine ligase 0.82 MCAODC_02295 pepA leucyl aminopeptidase low > 87
Escherichia coli ECRC102 0.54 NIAGMN_18530 gshA glutamate--cysteine ligase 0.82 NIAGMN_09640 pepA leucyl aminopeptidase 0.76 5
Escherichia coli Nissle 1917 0.54 ECOLIN_RS14990 glutamate--cysteine ligase 0.82 ECOLIN_RS24695 leucyl aminopeptidase low > 55
Escherichia coli BL21 0.54 ECD_02543 glutamate-cysteine ligase 0.82 ECD_04126 multifunctional aminopeptidase A: a cyteinylglycinase, transcription regulator and site-specific recombination factor low > 61
Escherichia coli ECRC100 0.54 OKFHMN_20760 gshA glutamate--cysteine ligase 0.82 OKFHMN_11790 pepA leucyl aminopeptidase low > 79
Escherichia coli ECRC99 0.54 KEDOAH_07375 gshA glutamate--cysteine ligase 0.82 KEDOAH_16360 pepA leucyl aminopeptidase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_01045 Glutamate--cysteine ligase 0.82 OHPLBJKB_03776 Cytosol aminopeptidase low > 74
Escherichia coli BW25113 0.54 b2688 gshA glutamate--cysteine ligase (NCBI) 0.82 b4260 pepA leucyl aminopeptidase (NCBI) low > 76
Escherichia coli ECOR38 0.54 HEPCGN_19955 gshA glutamate--cysteine ligase 0.82 HEPCGN_09980 pepA leucyl aminopeptidase low > 88
Escherichia fergusonii Becca 0.54 EFB2_01238 Glutamate--cysteine ligase 0.82 EFB2_04275 Cytosol aminopeptidase low > 86
Escherichia coli ECRC62 0.54 BNILDI_11160 gshA glutamate--cysteine ligase 0.82 BNILDI_07455 pepA leucyl aminopeptidase low > 75
Escherichia coli ECOR27 0.54 NOLOHH_12600 gshA glutamate--cysteine ligase 0.82 NOLOHH_04055 pepA leucyl aminopeptidase low > 76
Erwinia amylovora T8 0.53 OLJFJH_09625 glutamate--cysteine ligase 0.84 OLJFJH_07380 leucyl aminopeptidase low > 58
Klebsiella michiganensis M5al 0.53 BWI76_RS22120 glutamate--cysteine ligase 0.81 BWI76_RS03040 leucyl aminopeptidase low > 92
Dickeya dianthicola 67-19 0.53 HGI48_RS16305 glutamate--cysteine ligase 0.83 HGI48_RS01955 leucyl aminopeptidase low > 71
Erwinia tracheiphila SCR3 0.53 LU632_RS15690 gshA glutamate--cysteine ligase 0.84 LU632_RS20855 pepA leucyl aminopeptidase low > 73
Erwinia tracheiphila HP pepo 2.2 0.53 IJEDHG_01560 gshA glutamate--cysteine ligase 0.84 IJEDHG_14170 pepA leucyl aminopeptidase — —
Dickeya dianthicola ME23 0.53 DZA65_RS17400 glutamate--cysteine ligase 0.83 DZA65_RS02060 leucyl aminopeptidase low > 75
Pectobacterium carotovorum WPP14 0.53 HER17_RS05095 glutamate--cysteine ligase 0.81 HER17_RS19450 leucyl aminopeptidase 0.80 53
Dickeya dadantii 3937 0.52 DDA3937_RS16195 glutamate--cysteine ligase 0.83 DDA3937_RS01995 leucyl aminopeptidase low > 74
Pantoea sp. MT58 0.52 IAI47_04350 glutamate--cysteine ligase 0.83 IAI47_16795 leucyl aminopeptidase low > 76
Pantoea agglomerans CFBP13505 P0401 0.51 PagCFBP13505_RS16620 glutamate--cysteine ligase 0.83 PagCFBP13505_RS08910 leucyl aminopeptidase low > 74
Shewanella amazonensis SB2B 0.47 Sama_1058 glutamate--cysteine ligase (RefSeq) 0.81 Sama_0795 leucyl aminopeptidase (RefSeq) low > 62
Shewanella loihica PV-4 0.46 Shew_1227 glutamate--cysteine ligase (RefSeq) 0.81 Shew_0939 leucyl aminopeptidase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.46 SO3559 gshA glutamate--cysteine ligase (NCBI ptt file) 0.81 SO1368 pepA-2 cytosol aminopeptidase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.45 Shewana3_3160 glutamate-cysteine ligase (RefSeq) 0.81 Shewana3_3006 leucyl aminopeptidase (RefSeq) — —
Alteromonas macleodii MIT1002 0.44 MIT1002_01222 Glutamate--cysteine ligase 0.79 MIT1002_03197 Cytosol aminopeptidase low > 70
Pseudomonas sp. BP01 0.40 JOY50_RS18365 gshA glutamate--cysteine ligase 0.52 JOY50_RS11265 leucyl aminopeptidase — —
Pseudomonas putida KT2440 0.39 PP_0243 Glutamate--cysteine ligase 0.52 PP_0980 Probable cytosol aminopeptidase — —
Pseudomonas fluorescens FW300-N2C3 0.39 AO356_10185 glutamate--cysteine ligase 0.54 AO356_17470 aminopeptidase low > 104
Pseudomonas fluorescens FW300-N2E2 0.39 Pf6N2E2_3908 Glutamate--cysteine ligase (EC 6.3.2.2) 0.54 Pf6N2E2_5420 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 103
Kangiella aquimarina DSM 16071 0.39 B158DRAFT_2251 glutamate-cysteine ligase (EC 6.3.2.2) 0.60 B158DRAFT_1167 Leucyl aminopeptidase — —
Pseudomonas aeruginosa PUPa3 0.39 DQ20_RS50230 gshA;go_function=glutamate-cysteine glutamate--cysteine ligase 0.52 DQ20_RS49000 leucyl aminopeptidase — —
Pseudomonas aeruginosa MRSN321 0.39 DY961_RS11885 gshA;go_function=glutamate-cysteine glutamate--cysteine ligase 0.52 DY961_RS13735 leucyl aminopeptidase — —
Pseudomonas sp. RS175 0.39 PFR28_04865 Glutamate--cysteine ligase 0.53 PFR28_03528 Cytosol aminopeptidase low > 88
Pseudomonas sp. SVBP6 0.39 COO64_RS00715 gshA glutamate--cysteine ligase 0.51 COO64_RS04415 leucyl aminopeptidase — —
Pseudomonas aeruginosa PA14 0.39 IKLFDK_27455 glutamate--cysteine ligase 0.51 IKLFDK_19730 leucyl aminopeptidase — —
Pseudomonas sp. DMC3 0.38 GFF4186 Glutamate--cysteine ligase 0.54 GFF1952 Cytosol aminopeptidase low > 89
Pseudomonas fluorescens FW300-N2E3 0.38 AO353_11730 glutamate--cysteine ligase 0.54 AO353_04535 aminopeptidase low > 101
Pseudomonas simiae WCS417 0.38 PS417_01155 glutamate--cysteine ligase 0.54 PS417_05165 cytosol aminopeptidase — —
Pseudomonas fluorescens GW456-L13 0.38 PfGW456L13_430 Glutamate--cysteine ligase (EC 6.3.2.2) 0.54 PfGW456L13_4846 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 87
Pseudomonas sp. S08-1 0.38 OH686_11110 glutamate--cysteine ligase 0.52 OH686_07810 Cytosol aminopeptidase PepA low > 80
Pseudomonas stutzeri RCH2 0.38 Psest_3998 glutamate--cysteine ligase 0.51 Psest_1235 Leucyl aminopeptidase low > 67
Pseudomonas lactucae CFBP13502 0.38 GEMAOFIL_00458 Glutamate--cysteine ligase 0.54 GEMAOFIL_01239 Cytosol aminopeptidase low > 96
Pseudomonas fluorescens SBW25 0.38 PFLU_RS01265 glutamate--cysteine ligase 0.54 PFLU_RS05235 leucyl aminopeptidase — —
Pseudomonas fluorescens SBW25-INTG 0.38 PFLU_RS01265 glutamate--cysteine ligase 0.54 PFLU_RS05235 leucyl aminopeptidase — —
Pseudomonas fluorescens FW300-N1B4 0.38 Pf1N1B4_1769 Glutamate--cysteine ligase (EC 6.3.2.2) 0.54 Pf1N1B4_898 Cytosol aminopeptidase PepA (EC 3.4.11.1) — —
Pseudomonas orientalis W4I3 0.38 QF045_RS04285 glutamate--cysteine ligase 0.54 QF045_RS08155 leucyl aminopeptidase low > 93
Pseudomonas syringae pv. syringae B728a ΔmexB 0.37 Psyr_0255 glutamate-cysteine ligase 0.54 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 — —
Burkholderia phytofirmans PsJN 0.37 BPHYT_RS00520 glutamate--cysteine ligase 0.51 BPHYT_RS04795 cytosol aminopeptidase low > 109
Pseudomonas syringae pv. syringae B728a 0.37 Psyr_0255 glutamate-cysteine ligase 0.54 Psyr_1091 aminopeptidase A, Metallo peptidase, MEROPS family M17 low > 86
Pseudomonas segetis P6 0.37 MPMX49_00768 Glutamate--cysteine ligase 0.53 MPMX49_03516 Cytosol aminopeptidase 0.65 69
Paraburkholderia bryophila 376MFSha3.1 0.37 H281DRAFT_02339 glutamate-cysteine ligase 0.51 H281DRAFT_00123 aminopeptidase A. Metallo peptidase. MEROPS family M17 low > 103
Paraburkholderia graminis OAS925 0.36 ABIE53_000313 glutamate--cysteine ligase 0.51 ABIE53_001235 leucyl aminopeptidase low > 113
Herbaspirillum seropedicae SmR1 0.35 HSERO_RS07300 glutamate--cysteine ligase 0.46 HSERO_RS15600 cytosol aminopeptidase low > 78
Paraburkholderia sabiae LMG 24235 0.34 QEN71_RS29600 glutamate--cysteine ligase 0.51 QEN71_RS25205 leucyl aminopeptidase low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF3561 Glutamate--cysteine ligase (EC 6.3.2.2) 0.36 GFF4309 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 90
Acinetobacter baumannii LAC-4 0.34 RR41_RS00545 glutamate--cysteine ligase 0.38 RR41_RS17825 leucyl aminopeptidase low > 55
Variovorax sp. OAS795 0.33 ABID97_RS20965 glutamate--cysteine ligase 0.37 ABID97_RS16580 leucyl aminopeptidase low > 91
Variovorax sp. SCN45 0.33 GFF7064 Glutamate--cysteine ligase (EC 6.3.2.2) 0.36 GFF240 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 127
Castellaniella sp019104865 MT123 0.33 ABCV34_RS10935 glutamate--cysteine ligase 0.43 ABCV34_RS08295 leucyl aminopeptidase — —
Marinobacter adhaerens HP15 0.33 HP15_217 glutamate--cysteine ligase 0.46 HP15_1315 leucyl aminopeptidase — —
Acidovorax sp. GW101-3H11 0.33 Ac3H11_3126 Glutamate--cysteine ligase (EC 6.3.2.2) 0.36 Ac3H11_2399 Cytosol aminopeptidase PepA (EC 3.4.11.1) low > 79

Not shown: 1 genomes with orthologs for CSW01_02970 only; 32 genomes with orthologs for CSW01_12680 only