Conservation of cofitness between CSW01_05685 and CSW01_06990 in Vibrio cholerae E7946 ATCC 55056

54 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_05685 FAD-dependent oxidoreductase 1.0 CSW01_06990 QacE family quaternary ammonium compound efflux SMR transporter 0.52 15
Shewanella sp. ANA-3 0.59 Shewana3_1169 amine oxidase (RefSeq) 0.51 Shewana3_1676 small multidrug resistance protein (RefSeq) — —
Shewanella oneidensis MR-1 0.57 SO3381 conserved hypothetical protein (NCBI ptt file) 0.51 SO1901 sugE sugE protein (NCBI ptt file) low > 76
Pseudomonas sp. S08-1 0.56 OH686_07865 Amine oxidase, flavin-containing 0.61 OH686_19635 small multidrug resistance family (SMR) protein low > 80
Pectobacterium carotovorum WPP14 0.56 HER17_RS10560 FAD-dependent oxidoreductase 0.46 HER17_RS09145 multidrug efflux SMR transporter low > 75
Pseudomonas syringae pv. syringae B728a 0.56 Psyr_0958 amine oxidase, flavin-containing 0.33 Psyr_0541 Small multidrug resistance protein low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.56 Psyr_0958 amine oxidase, flavin-containing 0.33 Psyr_0541 Small multidrug resistance protein low > 86
Rahnella sp. WP5 0.54 EX31_RS23985 FAD-dependent oxidoreductase 0.47 EX31_RS00585 multidrug efflux SMR transporter low > 89
Pseudomonas orientalis W4I3 0.54 QF045_RS06630 FAD-dependent oxidoreductase 0.63 QF045_RS11900 quaternary ammonium compound efflux SMR transporter SugE low > 93
Pseudomonas lactucae CFBP13502 0.54 GEMAOFIL_00936 hypothetical protein 0.62 GEMAOFIL_01970 Guanidinium exporter low > 96
Pseudomonas putida KT2440 0.54 PP_2736 conserved protein of unknown function 0.64 PP_1701 transporter — —
Enterobacter asburiae PDN3 0.54 EX28DRAFT_1373 Predicted NAD/FAD-binding protein 0.59 EX28DRAFT_3348 Membrane transporters of cations and cationic drugs low > 76
Pseudomonas segetis P6 0.54 ACVTMO_RS06665 NAD(P)/FAD-dependent oxidoreductase 0.62 ACVTMO_RS08600 sugE quaternary ammonium compound efflux SMR transporter SugE low > 75
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS03700 FAD-dependent oxidoreductase 0.62 PFLU_RS09245 quaternary ammonium compound efflux SMR transporter SugE low > 109
Pseudomonas fluorescens SBW25 0.54 PFLU_RS03700 FAD-dependent oxidoreductase 0.62 PFLU_RS09245 quaternary ammonium compound efflux SMR transporter SugE low > 109
Pseudomonas fluorescens FW300-N2E2 0.54 Pf6N2E2_1348 COG2907: Amine oxidase, flavin-containing 0.63 Pf6N2E2_5766 Quaternary ammonium compound-resistance protein SugE low > 103
Pseudomonas fluorescens FW300-N2C3 0.53 AO356_25325 FAD-dependent oxidoreductase 0.63 AO356_19255 molecular chaperone low > 104
Enterobacter sp. TBS_079 0.53 MPMX20_02175 hypothetical protein 0.58 MPMX20_00430 Guanidinium exporter low > 85
Pseudomonas sp. BP01 0.53 JOY50_RS03420 NAD(P)/FAD-dependent oxidoreductase 0.65 JOY50_RS28055 sugE quaternary ammonium compound efflux SMR transporter SugE — —
Pseudomonas sp. RS175 0.53 PFR28_02036 hypothetical protein 0.63 PFR28_03184 Guanidinium exporter low > 88
Klebsiella pneumoniae MKP103 0.53 KDGMDA_11810 FAD-dependent oxidoreductase 0.55 KDGMDA_10925 quaternary ammonium compound efflux SMR transporter SugE low > 94
Pseudomonas sp. DMC3 0.52 GFF4482 hypothetical protein 0.63 GFF2572 Guanidinium exporter low > 89
Klebsiella michiganensis M5al 0.52 BWI76_RS12575 FAD-dependent oxidoreductase 0.58 BWI76_RS02430 multidrug transporter low > 92
Pseudomonas protegens RBAN4 0.52 FABNJH_25920 Amine oxidase, flavin-containing 0.64 FABNJH_22780 sugE quaternary ammonium compound efflux SMR transporter SugE — —
Erwinia amylovora T8 0.52 OLJFJH_16590 FAD-dependent oxidoreductase 0.28 OLJFJH_08005 multidrug/spermidine efflux SMR transporter subunit MdtJ low > 58
Pseudomonas simiae WCS417 0.52 PS417_03650 FAD-dependent oxidoreductase 0.62 PS417_09235 molecular chaperone low > 88
Alteromonas macleodii MIT1002 0.51 MIT1002_02686 protoporphyrinogen oxidase 0.35 MIT1002_00131 Quaternary ammonium compound-resistance protein SugE low > 70
Marinobacter adhaerens HP15 0.51 HP15_1771 dehydrogenase 0.32 HP15_958 small multidrug resistance protein low > 73
Klebsiella pneumoniae MRSN742743 0.50 GJGHJB_04416 ppro0129 Amine oxidase domain-containing protein 0.55 GJGHJB_04596 sugE quaternary ammonium compound efflux SMR transporter SugE low > 83
Methylophilus sp. DMC18 0.48 GFF718 hypothetical protein 0.57 GFF97 Guanidinium exporter low > 43
Rhodanobacter denitrificans FW104-10B01 0.45 LRK54_RS07525 FAD-dependent oxidoreductase 0.54 LRK54_RS00480 quaternary ammonium compound efflux SMR transporter SugE low > 59
Rhodanobacter denitrificans MT42 0.45 LRK55_RS07265 FAD-dependent oxidoreductase 0.54 LRK55_RS00220 quaternary ammonium compound efflux SMR transporter SugE low > 63
Xanthomonas campestris pv. campestris strain 8004 0.42 Xcc-8004.3604.1 COG2907: Amine oxidase, flavin-containing 0.44 Xcc-8004.627.1 Quaternary ammonium compound-resistance protein SugE — —
Lysobacter sp. OAE881 0.42 ABIE51_RS02530 FAD-dependent oxidoreductase 0.57 ABIE51_RS07490 quaternary ammonium compound efflux SMR transporter SugE — —
Acidovorax sp. GW101-3H11 0.42 Ac3H11_1216 COG2907: Amine oxidase, flavin-containing 0.34 Ac3H11_2948 Ethidium bromide-methyl viologen resistance protein EmrE low > 79
Ralstonia sp. UNC404CL21Col 0.42 ABZR87_RS21065 FAD-dependent oxidoreductase 0.41 ABZR87_RS21585 multidrug efflux SMR transporter low > 80
Bosea sp. OAE506 0.41 ABIE41_RS10275 NAD(P)/FAD-dependent oxidoreductase 0.56 ABIE41_RS19675 quaternary ammonium compound efflux SMR transporter SugE low > 77
Burkholderia phytofirmans PsJN 0.41 BPHYT_RS05115 NADH-ubiquinone oxidoreductase subunit 6 0.49 BPHYT_RS06470 membrane protein low > 109
Paraburkholderia bryophila 376MFSha3.1 0.40 H281DRAFT_01466 Predicted NAD/FAD-binding protein 0.52 H281DRAFT_04535 quaternary ammonium compound-resistance protein SugE low > 103
Rhizobium sp. OAE497 0.39 ABIE40_RS08315 FAD-dependent oxidoreductase 0.59 ABIE40_RS09885 quaternary ammonium compound efflux SMR transporter SugE low > 107
Herbaspirillum seropedicae SmR1 0.39 HSERO_RS05275 NADH-ubiquinone oxidoreductase subunit 6 0.28 HSERO_RS23145 multidrug transporter low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.39 GFF2528 COG2907: Amine oxidase, flavin-containing 0.32 GFF4245 Ethidium bromide-methyl viologen resistance protein EmrE low > 90
Variovorax sp. SCN45 0.39 GFF5437 Amine oxidase, flavin-containing 0.30 GFF2129 small multidrug resistance family (SMR) protein low > 127
Cupriavidus basilensis FW507-4G11 0.38 RR42_RS29225 NADH-ubiquinone oxidoreductase subunit 6 0.27 RR42_RS14705 multidrug transporter low > 128
Paraburkholderia sabiae LMG 24235 0.38 QEN71_RS19695 FAD-dependent oxidoreductase 0.50 QEN71_RS24335 quaternary ammonium compound efflux SMR transporter SugE low > 153
Pedobacter sp. GW460-11-11-14-LB5 0.38 CA265_RS01010 NADP transhydrogenase subunit alpha 0.43 CA265_RS21580 QacE family quaternary ammonium compound efflux SMR transporter low > 88
Rhodospirillum rubrum S1H 0.38 Rru_A0723 Amine oxidase (NCBI) 0.50 Rru_A0272 Small multidrug resistance protein (NCBI) — —
Brevundimonas sp. GW460-12-10-14-LB2 0.36 A4249_RS05840 FAD-dependent oxidoreductase 0.43 A4249_RS15980 multidrug efflux SMR transporter low > 48
Dinoroseobacter shibae DFL-12 0.36 Dshi_0367 amine oxidase (RefSeq) 0.29 Dshi_1638 small multidrug resistance protein (RefSeq) low > 64
Azospirillum sp. SherDot2 0.36 MPMX19_05741 hypothetical protein 0.55 MPMX19_00878 Guanidinium exporter low > 112
Variovorax sp. OAS795 0.35 ABID97_RS21860 FAD-dependent oxidoreductase 0.54 ABID97_RS10520 quaternary ammonium compound efflux SMR transporter SugE 0.24 17
Caulobacter crescentus NA1000 0.35 CCNA_02683 FAD dependent oxidoreductase 0.56 CCNA_03556 multidrug efflux system protein low > 66
Caulobacter crescentus NA1000 Δfur 0.35 CCNA_02683 FAD dependent oxidoreductase 0.56 CCNA_03556 multidrug efflux system protein low > 67
Acinetobacter baumannii LAC-4 0.34 RR41_RS06580 FAD-dependent oxidoreductase 0.47 RR41_RS15715 multidrug efflux SMR transporter low > 55
Rhodopseudomonas palustris CGA009 0.34 TX73_013295 NAD/FAD-binding protein 0.56 TX73_011815 quaternary ammonium compound efflux SMR transporter SugE low > 86

Not shown: 10 genomes with orthologs for CSW01_05685 only; 45 genomes with orthologs for CSW01_06990 only