| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Klebsiella michiganensis M5al | 1.0 | BWI76_RS06780 | | MexE family multidrug efflux RND transporter periplasmic adaptor subunit | 1.0 | BWI76_RS25220 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.47 | 8 |
| Enterobacter sp. TBS_079 | 0.87 | MPMX20_01065 | | Multidrug efflux pump subunit AcrA | 0.76 | MPMX20_04099 | | Intermembrane phospholipid transport system binding protein MlaD | low | > 85 |
| Enterobacter asburiae PDN3 | 0.84 | EX28DRAFT_2495 | | RND family efflux transporter, MFP subunit | 0.77 | EX28DRAFT_3247 | | mce related protein | low | > 76 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.83 | OHPLBJKB_03211 | | Multidrug efflux pump subunit AcrA | 0.81 | OHPLBJKB_00507 | | putative phospholipid ABC transporter-binding protein MlaD | 0.55 | 10 |
| Escherichia coli BL21 | 0.83 | ECD_00414 | | multidrug efflux system | 0.81 | ECD_03058 | | OM lipid asymmetry maintenance protein; membrane-anchored ABC family periplasmic binding protein | low | > 61 |
| Escherichia coli ECRC102 | 0.83 | NIAGMN_06255 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | NIAGMN_15745 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | — | — |
| Escherichia coli ECRC99 | 0.83 | KEDOAH_19765 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | KEDOAH_10165 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | — | — |
| Escherichia coli ECRC62 | 0.83 | BNILDI_22550 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | BNILDI_01750 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | low | > 75 |
| Escherichia coli ECRC98 | 0.83 | JDDGAC_11850 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | JDDGAC_21610 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | low | > 86 |
| Escherichia coli ECOR27 | 0.83 | NOLOHH_01135 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | NOLOHH_09785 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | low | > 75 |
| Escherichia coli ECRC100 | 0.83 | OKFHMN_08200 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | OKFHMN_17985 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | low | > 80 |
| Escherichia coli ECRC101 | 0.83 | MCAODC_27425 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | MCAODC_08505 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | low | > 87 |
| Escherichia coli BW25113 | 0.83 | b0463 | acrA | multidrug efflux system (NCBI) | 0.81 | b3193 | yrbD | predicted ABC-type organic solvent transporter (NCBI) | 0.34 | 18 |
| Escherichia coli Nissle 1917 | 0.82 | ECOLIN_RS02755 | | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.80 | ECOLIN_RS18380 | | outer membrane lipid asymmetry maintenance protein MlaD | — | — |
| Escherichia fergusonii Becca | 0.82 | EFB2_03595 | | Multidrug efflux pump subunit AcrA | 0.81 | EFB2_00630 | | Intermembrane phospholipid transport system binding protein MlaD | low | > 86 |
| Escherichia coli ECOR38 | 0.82 | HEPCGN_06815 | acrA | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | 0.81 | HEPCGN_16860 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | low | > 87 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.78 | GFF4380 | | Membrane fusion protein of RND family multidrug efflux pump | 0.81 | GFF2937 | | Uncharacterized ABC transporter, periplasmic component YrbD | low | > 78 |
| Pantoea sp. MT58 | 0.74 | IAI47_14510 | | efflux RND transporter periplasmic adaptor subunit | 0.65 | IAI47_17135 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 76 |
| Rahnella sp. WP5 | 0.74 | EX31_RS22475 | | efflux RND transporter periplasmic adaptor subunit | 0.64 | EX31_RS12445 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 89 |
| Serratia liquefaciens MT49 | 0.74 | IAI46_05190 | | multidrug efflux RND transporter periplasmic adaptor subunit SdeX | 0.73 | IAI46_22420 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 86 |
| Erwinia tracheiphila SCR3 | 0.74 | LU632_RS18180 | | efflux RND transporter periplasmic adaptor subunit | 0.59 | LU632_RS21235 | mlaD | outer membrane lipid asymmetry maintenance protein MlaD | — | — |
| Dickeya dadantii 3937 | 0.71 | DDA3937_RS05740 | | efflux RND transporter periplasmic adaptor subunit | 0.73 | DDA3937_RS01575 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 74 |
| Dickeya dianthicola 67-19 | 0.69 | HGI48_RS05795 | | efflux RND transporter periplasmic adaptor subunit | 0.72 | HGI48_RS01490 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 71 |
| Dickeya dianthicola ME23 | 0.69 | DZA65_RS06120 | | efflux RND transporter periplasmic adaptor subunit | 0.72 | DZA65_RS01555 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.59 | 58 |
| Pectobacterium carotovorum WPP14 | 0.68 | HER17_RS15735 | | efflux RND transporter periplasmic adaptor subunit | 0.73 | HER17_RS20015 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 75 |
| Pseudomonas fluorescens FW300-N2E2 | 0.51 | Pf6N2E2_2823 | | Multidrug efflux RND membrane fusion protein MexC | 0.33 | Pf6N2E2_3258 | | Uncharacterized ABC transporter, periplasmic component YrbD | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.51 | AO356_04875 | | antibiotic transporter | 0.33 | AO356_06995 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.41 | 45 |
| Pseudomonas sp. RS175 | 0.51 | PFR28_00632 | | putative efflux pump periplasmic linker TtgA | 0.33 | PFR28_00181 | | Intermembrane phospholipid transport system binding protein MlaD | low | > 88 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.51 | Psyr_4007 | | Secretion protein HlyD | 0.33 | Psyr_4139 | | Mce4/Rv3499c/MTV023.06c protein | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.51 | Psyr_4007 | | Secretion protein HlyD | 0.33 | Psyr_4139 | | Mce4/Rv3499c/MTV023.06c protein | 0.35 | 29 |
| Pseudomonas sp. S08-1 | 0.50 | OH686_16045 | | Multidrug efflux system, membrane fusion component | 0.33 | OH686_08500 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 80 |
| Pseudomonas stutzeri RCH2 | 0.48 | Psest_0309 | | RND family efflux transporter, MFP subunit | 0.32 | Psest_3305 | | ABC-type transport system involved in resistance to organic solvents, periplasmic component | 0.25 | 46 |
| Pseudomonas fluorescens SBW25-INTG | 0.48 | PFLU_RS06810 | | efflux RND transporter periplasmic adaptor subunit | 0.33 | PFLU_RS04440 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.37 | 32 |
| Pseudomonas fluorescens GW456-L13 | 0.48 | PfGW456L13_4580 | | Multidrug efflux RND membrane fusion protein MexC | 0.33 | PfGW456L13_5006 | | Uncharacterized ABC transporter, periplasmic component YrbD | low | > 87 |
| Pseudomonas fluorescens SBW25 | 0.48 | PFLU_RS06810 | | efflux RND transporter periplasmic adaptor subunit | 0.33 | PFLU_RS04440 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.62 | 54 |
| Pseudomonas simiae WCS417 | 0.48 | PS417_06775 | | antibiotic transporter | 0.33 | PS417_04385 | | organic solvent ABC transporter substrate-binding protein | 0.42 | 32 |
| Pseudomonas putida KT2440 | 0.48 | PP_1386 | | Probable efflux pump periplasmic linker TtgA | 0.34 | PP_0960 | | phospholipid ABC transporter binding protein | 0.46 | 6 |
| Pseudomonas fluorescens FW300-N1B4 | 0.48 | Pf1N1B4_3247 | | Multidrug efflux RND membrane fusion protein MexC | 0.32 | Pf1N1B4_1072 | | Uncharacterized ABC transporter, periplasmic component YrbD | — | — |
| Herbaspirillum seropedicae SmR1 | 0.47 | HSERO_RS06810 | | hemolysin D | 0.37 | HSERO_RS20390 | | ABC transporter substrate-binding protein | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.47 | AO353_17300 | | antibiotic transporter | 0.34 | AO353_05140 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.45 | 27 |
| Azospirillum brasilense Sp245 | 0.46 | AZOBR_RS30180 | | hemolysin D | 0.19 | AZOBR_RS11990 | | ATPase AAA | low | > 97 |
| Paraburkholderia sabiae LMG 24235 | 0.46 | QEN71_RS29870 | | efflux RND transporter periplasmic adaptor subunit | 0.38 | QEN71_RS27910 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.48 | 134 |
| Burkholderia phytofirmans PsJN | 0.46 | BPHYT_RS34600 | | hemolysin D | 0.39 | BPHYT_RS17755 | | ABC transporter substrate-binding protein | low | > 109 |
| Cupriavidus basilensis FW507-4G11 | 0.45 | RR42_RS32415 | | hemolysin D | 0.39 | RR42_RS18960 | | ABC transporter substrate-binding protein | low | > 128 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.45 | H281DRAFT_01000 | | membrane fusion protein, multidrug efflux system | 0.38 | H281DRAFT_05643 | | phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein | low | > 103 |
| Shewanella amazonensis SB2B | 0.44 | Sama_3553 | | multidrug resistance protein AcrA/AcrE family (RefSeq) | 0.40 | Sama_3079 | | mce-related protein (RefSeq) | low | > 62 |
| Ralstonia solanacearum IBSBF1503 | 0.44 | RALBFv3_RS19790 | | efflux RND transporter periplasmic adaptor subunit | 0.39 | RALBFv3_RS06890 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 76 |
| Ralstonia solanacearum UW163 | 0.44 | UW163_RS19385 | | efflux RND transporter periplasmic adaptor subunit | 0.39 | UW163_RS06725 | | outer membrane lipid asymmetry maintenance protein MlaD | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.44 | DVU2817 | acrA | multidrug resistance protein (TIGR) | 0.20 | DVU1244 | | conserved hypothetical protein (TIGR) | low | > 55 |
| Ralstonia sp. UNC404CL21Col | 0.44 | ABZR87_RS05310 | | efflux RND transporter periplasmic adaptor subunit | 0.38 | ABZR87_RS02545 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 80 |
| Ralstonia solanacearum GMI1000 | 0.44 | RS_RS21035 | | efflux RND transporter periplasmic adaptor subunit | 0.39 | RS_RS14835 | | outer membrane lipid asymmetry maintenance protein MlaD | low | > 80 |
| Shewanella oneidensis MR-1 | 0.44 | SO4693 | | multidrug resistance protein, AcrA/AcrE family (NCBI ptt file) | 0.38 | SO3952 | | mce-related protein (NCBI ptt file) | low | > 76 |
| Ralstonia solanacearum PSI07 | 0.44 | RPSI07_RS23900 | | efflux RND transporter periplasmic adaptor subunit | 0.39 | RPSI07_RS10345 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.53 | 31 |
| Shewanella sp. ANA-3 | 0.44 | Shewana3_4046 | | RND family efflux transporter MFP subunit (RefSeq) | 0.38 | Shewana3_0680 | | hypothetical protein (RefSeq) | low | > 73 |
| Acinetobacter radioresistens SK82 | 0.40 | MPMX26_00690 | | Multidrug efflux pump subunit AcrA | 0.24 | MPMX26_02739 | | Intermembrane phospholipid transport system binding protein MlaD | low | > 36 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.38 | GFF5686 | | RND efflux system, membrane fusion protein CmeA | 0.39 | GFF1323 | | Uncharacterized ABC transporter, periplasmic component YrbD | low | > 90 |
| Variovorax sp. OAS795 | 0.38 | ABID97_RS00320 | | efflux RND transporter periplasmic adaptor subunit | 0.38 | ABID97_RS23205 | | outer membrane lipid asymmetry maintenance protein MlaD | 0.48 | 26 |
| Acidovorax sp. GW101-3H11 | 0.34 | Ac3H11_4449 | | RND efflux system, membrane fusion protein CmeA | 0.39 | Ac3H11_4714 | | Uncharacterized ABC transporter, periplasmic component YrbD | low | > 79 |
| Castellaniella sp019104865 MT123 | 0.33 | ABCV34_RS04230 | | efflux RND transporter periplasmic adaptor subunit | 0.42 | ABCV34_RS11190 | | outer membrane lipid asymmetry maintenance protein MlaD | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.28 | DvMF_2164 | | efflux transporter, RND family, MFP subunit (RefSeq) | 0.21 | DvMF_0854 | | Mammalian cell entry related domain protein (RefSeq) | low | > 51 |
Not shown: 14 genomes with orthologs for BWI76_RS06780 only; 11 genomes with orthologs for BWI76_RS25220 only