Conservation of cofitness between BWI76_RS00805 and BWI76_RS24285 in Klebsiella michiganensis M5al

61 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Klebsiella michiganensis M5al 1.0 BWI76_RS00805 5,10-methylenetetrahydrofolate reductase 1.0 BWI76_RS24285 cystathionine beta-lyase 0.91 7
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF2329 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.89 GFF3120 Cystathionine beta-lyase (EC 4.4.1.8) low > 78
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4413 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.89 EX28DRAFT_3046 cystathionine beta-lyase, bacterial 0.56 46
Escherichia coli HS(pFamp)R (ATCC 700891) 0.95 OHPLBJKB_04109 5,10-methylenetetrahydrofolate reductase 0.89 OHPLBJKB_00693 Cystathionine beta-lyase MetC low > 73
Enterobacter sp. TBS_079 0.95 MPMX20_04529 5,10-methylenetetrahydrofolate reductase 0.89 MPMX20_03852 Cystathionine beta-lyase MetC 0.79 1
Escherichia coli BW25113 0.95 b3941 metF 5,10-methylenetetrahydrofolate reductase (NCBI) 0.88 b3008 metC cystathionine beta-lyase (NCBI) 0.93 38
Escherichia coli BL21 0.95 ECD_03827 5,10-methylenetetrahydrofolate reductase 0.88 ECD_02881 cystathionine beta-lyase, PLP-dependent 0.88 30
Escherichia coli ECRC62 0.95 BNILDI_05725 metF methylenetetrahydrofolate reductase 0.89 BNILDI_00780 metC cystathionine beta-lyase 0.99 7
Escherichia coli ECOR27 0.95 NOLOHH_05810 metF methylenetetrahydrofolate reductase 0.89 NOLOHH_10735 metC cystathionine beta-lyase 0.97 12
Escherichia coli ECRC98 0.95 JDDGAC_17290 metF methylenetetrahydrofolate reductase 0.88 JDDGAC_22595 metC cystathionine beta-lyase 0.98 9
Escherichia coli ECRC102 0.95 NIAGMN_11420 metF methylenetetrahydrofolate reductase 0.88 NIAGMN_16725 metC cystathionine beta-lyase
Escherichia coli ECRC99 0.95 KEDOAH_14495 metF methylenetetrahydrofolate reductase 0.88 KEDOAH_09185 metC cystathionine beta-lyase
Escherichia coli ECRC100 0.95 OKFHMN_13665 metF methylenetetrahydrofolate reductase 0.88 OKFHMN_18960 metC cystathionine beta-lyase 0.98 23
Escherichia coli ECRC101 0.95 MCAODC_04165 metF methylenetetrahydrofolate reductase 0.88 MCAODC_09475 metC cystathionine beta-lyase 0.99 1
Escherichia coli ECOR38 0.95 HEPCGN_12310 metF methylenetetrahydrofolate reductase 0.88 HEPCGN_17825 metC cystathionine beta-lyase 0.97 5
Escherichia fergusonii Becca 0.94 EFB2_04672 5,10-methylenetetrahydrofolate reductase 0.89 EFB2_00802 Cystathionine beta-lyase MetC low > 86
Escherichia coli Nissle 1917 0.94 ECOLIN_RS22760 methylenetetrahydrofolate reductase 0.88 ECOLIN_RS17315 cystathionine beta-lyase 0.95 13
Pantoea sp. MT58 0.92 IAI47_00890 methylenetetrahydrofolate reductase 0.75 IAI47_03215 cystathionine beta-lyase low > 76
Serratia liquefaciens MT49 0.92 IAI46_24530 methylenetetrahydrofolate reductase 0.77 IAI46_21725 cystathionine beta-lyase low > 86
Dickeya dadantii 3937 0.91 DDA3937_RS00960 methylenetetrahydrofolate reductase 0.76 DDA3937_RS01815 cystathionine beta-lyase 0.43 20
Rahnella sp. WP5 0.91 EX31_RS14205 methylenetetrahydrofolate reductase 0.77 EX31_RS08025 cystathionine beta-lyase low > 89
Pectobacterium carotovorum WPP14 0.90 HER17_RS00950 methylenetetrahydrofolate reductase 0.77 HER17_RS19690 cystathionine beta-lyase low > 75
Dickeya dianthicola 67-19 0.90 HGI48_RS20415 methylenetetrahydrofolate reductase 0.75 HGI48_RS01710 cystathionine beta-lyase low > 71
Dickeya dianthicola ME23 0.90 DZA65_RS21460 methylenetetrahydrofolate reductase 0.75 DZA65_RS01785 cystathionine beta-lyase 0.75 11
Erwinia tracheiphila SCR3 0.87 LU632_RS19630 metF methylenetetrahydrofolate reductase 0.74 LU632_RS20545 metC cystathionine beta-lyase low > 74
Vibrio cholerae E7946 ATCC 55056 0.78 CSW01_13560 methylenetetrahydrofolate reductase 0.60 CSW01_08400 cystathionine beta-lyase low > 62
Shewanella oneidensis MR-1 0.76 SO4054 metF 5,10-methylenetetrahydrofolate reductase (NCBI ptt file) 0.50 SO2191 metC cystathionine beta-lyase (NCBI ptt file) 0.98 7
Shewanella amazonensis SB2B 0.76 Sama_3169 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.50 Sama_2008 cystathionine beta-lyase (RefSeq) low > 62
Shewanella sp. ANA-3 0.76 Shewana3_3612 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.50 Shewana3_2414 cystathionine beta-lyase (RefSeq) 0.92 39
Shewanella loihica PV-4 0.75 Shew_0522 metF 5,10-methylenetetrahydrofolate reductase (RefSeq) 0.52 Shew_1789 cystathionine beta-lyase (RefSeq) 0.98 26
Azospirillum brasilense Sp245 0.55 AZOBR_RS09540 5 10-methylenetetrahydrofolate reductase 0.43 AZOBR_RS08650 cystathionine beta-lyase 0.76 10
Magnetospirillum magneticum AMB-1 0.55 AMB_RS02230 methylenetetrahydrofolate reductase 0.40 AMB_RS06585 cystathionine beta-lyase
Azospirillum sp. SherDot2 0.55 MPMX19_00635 5,10-methylenetetrahydrofolate reductase 0.39 MPMX19_01339 Cystathionine beta-lyase MetC low > 112
Sphingomonas koreensis DSMZ 15582 0.54 Ga0059261_0992 5,10-methylenetetrahydrofolate reductase, prokaryotic form 0.44 Ga0059261_1388 cystathionine beta-lyase, bacterial low > 68
Bosea sp. OAE506 0.52 ABIE41_RS12475 methylenetetrahydrofolate reductase [NAD(P)H] 0.28 ABIE41_RS01480 cystathionine beta-lyase low > 77
Rhodospirillum rubrum S1H 0.52 Rru_A1530 5,10-methylenetetrahydrofolate reductase (NCBI) 0.39 Rru_A1613 Cystathionine beta-lyase (NCBI) low > 58
Caulobacter crescentus NA1000 Δfur 0.48 CCNA_02224 methylenetetrahydrofolate reductase 0.37 CCNA_01491 cystathionine beta-lyase low > 67
Caulobacter crescentus NA1000 0.48 CCNA_02224 methylenetetrahydrofolate reductase 0.37 CCNA_01491 cystathionine beta-lyase low > 66
Rhodopseudomonas palustris CGA009 0.46 TX73_019175 methylenetetrahydrofolate reductase [NAD(P)H] 0.40 TX73_013235 cystathionine beta-lyase low > 86
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS07925 methylenetetrahydrofolate reductase [NAD(P)H] 0.29 A4249_RS05585 cystathionine beta-lyase low > 48
Rhizobium sp. OAE497 0.41 ABIE40_RS11950 methylenetetrahydrofolate reductase [NAD(P)H] 0.39 ABIE40_RS08820 cystathionine beta-lyase low > 107
Paraburkholderia sabiae LMG 24235 0.41 QEN71_RS28715 methylenetetrahydrofolate reductase [NAD(P)H] 0.35 QEN71_RS22165 cystathionine beta-lyase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.40 H281DRAFT_05801 5,10-methylenetetrahydrofolate reductase (NAD(P)) 0.34 H281DRAFT_00859 cystathionine beta-lyase low > 103
Cupriavidus basilensis FW507-4G11 0.39 RR42_RS01385 5,10-methylenetetrahydrofolate reductase 0.34 RR42_RS07655 cystathionine beta-lyase low > 128
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS18705 5,10-methylenetetrahydrofolate reductase 0.34 BPHYT_RS09190 cystathionine beta-lyase low > 109
Agrobacterium fabrum C58 0.39 Atu2123 methylenetetrahydrofolate reductase 0.37 Atu1575 cystathionine beta lyase low > 89
Ralstonia solanacearum PSI07 0.38 RPSI07_RS23495 methylenetetrahydrofolate reductase [NAD(P)H] 0.34 RPSI07_RS02185 cystathionine beta-lyase low > 81
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS04865 methylenetetrahydrofolate reductase [NAD(P)H] 0.37 ABZR87_RS11250 cystathionine beta-lyase low > 80
Ralstonia solanacearum GMI1000 0.38 RS_RS00460 methylenetetrahydrofolate reductase [NAD(P)H] 0.32 RS_RS08260 cystathionine beta-lyase low > 80
Ralstonia solanacearum UW163 0.38 UW163_RS03705 methylenetetrahydrofolate reductase [NAD(P)H] 0.33 UW163_RS18620 cystathionine beta-lyase
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS09875 methylenetetrahydrofolate reductase [NAD(P)H] 0.33 RALBFv3_RS20555 cystathionine beta-lyase low > 76
Sinorhizobium meliloti 1021 0.37 SMc01843 5,10-methylenetetrahydrofolate reductase 0.41 SMc02117 cystathionine beta-lyase 0.65 100
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08015 5,10-methylenetetrahydrofolate reductase 0.37 AO353_24330 cystathionine beta-lyase low > 101
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS21425 5,10-methylenetetrahydrofolate reductase 0.31 HSERO_RS14995 cystathionine beta-lyase low > 78
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.33 Psyr_0607 cystathionine beta-lyase low > 86
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0459 5,10-methylenetetrahydrofolate reductase 0.33 Psyr_0607 cystathionine beta-lyase low > 86
Castellaniella sp019104865 MT123 0.35 ABCV34_RS13550 methylenetetrahydrofolate reductase [NAD(P)H] 0.32 ABCV34_RS12385 PLP-dependent aspartate aminotransferase family protein low > 48
Hydrogenophaga sp. GW460-11-11-14-LB1 0.34 GFF1692 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.41 GFF5026 Cystathionine beta-lyase (EC 4.4.1.8)
Acidovorax sp. GW101-3H11 0.34 Ac3H11_3045 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.29 Ac3H11_4146 Cystathionine beta-lyase (EC 4.4.1.8) low > 79
Variovorax sp. OAS795 0.33 ABID97_RS25015 methylenetetrahydrofolate reductase [NAD(P)H] 0.34 ABID97_RS22430 cystathionine beta-lyase low > 91
Variovorax sp. SCN45 0.32 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) 0.36 GFF1749 Cystathionine beta-lyase (EC 4.4.1.8) low > 127
Acinetobacter radioresistens SK82 0.32 MPMX26_01002 5,10-methylenetetrahydrofolate reductase 0.21 MPMX26_02724 Cystathionine beta-lyase 0.49 36

Not shown: 38 genomes with orthologs for BWI76_RS00805 only; 0 genomes with orthologs for BWI76_RS24285 only