Conservation of cofitness between Atu2155 and Atu2791 in Agrobacterium fabrum C58

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu2155 methionine synthase 1.0 Atu2791 3-isopropylmalate dehydrogenase 0.86 5
Rhizobium sp. OAE497 0.89 ABIE40_RS12135 methionine synthase 0.89 ABIE40_RS19050 3-isopropylmalate dehydrogenase 0.95 6
Sinorhizobium meliloti 1021 0.79 SMc03112 B12-dependent methionine synthase 0.90 SMc04405 3-isopropylmalate dehydrogenase 0.98 6
Rhodopseudomonas palustris CGA009 0.71 TX73_019180 methionine synthase 0.72 TX73_001175 3-isopropylmalate dehydrogenase — —
Marinobacter adhaerens HP15 0.62 HP15_1792 B12-dependent methionine synthase 0.54 HP15_1832 3-isopropylmalate dehydrogenase 0.41 11
Pseudomonas stutzeri RCH2 0.61 Psest_2102 5-methyltetrahydrofolate--homocysteine methyltransferase 0.54 Psest_2589 3-isopropylmalate dehydrogenase low > 67
Mucilaginibacter yixingensis YX-36 DSM 26809 0.61 ABZR88_RS20930 methionine synthase 0.41 ABZR88_RS11605 3-isopropylmalate dehydrogenase — —
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_2466 methionine synthase (B12-dependent) (EC 2.1.1.13) 0.53 B158DRAFT_1322 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 40
Pedobacter sp. GW460-11-11-14-LB5 0.60 CA265_RS23440 methionine synthase 0.40 CA265_RS15850 3-isopropylmalate dehydrogenase 0.95 25
Pseudomonas sp. S08-1 0.60 OH686_03335 methionine synthase 0.53 OH686_04470 3-isopropylmalate dehydrogenase low > 80
Pseudomonas putida KT2440 0.60 PP_2375 cobalamin-dependent methionine synthase 0.55 PP_1988 3-isopropylmalate dehydrogenase 0.45 49
Shewanella loihica PV-4 0.60 Shew_0710 metH B12-dependent methionine synthase (RefSeq) 0.38 Shew_3471 3-isopropylmalate dehydrogenase (RefSeq) 0.93 3
Serratia liquefaciens MT49 0.60 IAI46_23155 methionine synthase 0.43 IAI46_03350 3-isopropylmalate dehydrogenase low > 86
Pseudomonas sp. RS175 0.60 PFR28_01369 Methionine synthase 0.56 PFR28_02821 3-isopropylmalate dehydrogenase low > 88
Shewanella amazonensis SB2B 0.60 Sama_0758 metH B12-dependent methionine synthase (RefSeq) 0.38 Sama_0336 3-isopropylmalate dehydrogenase (RefSeq) 0.90 14
Dickeya dianthicola ME23 0.60 DZA65_RS20250 methionine synthase 0.43 DZA65_RS19205 3-isopropylmalate dehydrogenase low > 75
Dickeya dadantii 3937 0.60 DDA3937_RS19040 methionine synthase 0.42 DDA3937_RS18120 3-isopropylmalate dehydrogenase low > 74
Rahnella sp. WP5 0.60 EX31_RS11760 methionine synthase 0.42 EX31_RS03685 3-isopropylmalate dehydrogenase 0.69 73
Pontibacter actiniarum KMM 6156, DSM 19842 0.59 CA264_16785 methionine synthase 0.35 CA264_09445 3-isopropylmalate dehydrogenase low > 74
Shewanella sp. ANA-3 0.59 Shewana3_3282 metH B12-dependent methionine synthase (RefSeq) 0.39 Shewana3_3760 3-isopropylmalate dehydrogenase (RefSeq) 0.71 47
Pseudomonas fluorescens FW300-N2E2 0.59 Pf6N2E2_2068 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.56 Pf6N2E2_66 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 103
Pseudomonas fluorescens FW300-N1B4 0.59 Pf1N1B4_5661 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.56 Pf1N1B4_12 3-isopropylmalate dehydrogenase (EC 1.1.1.85) 0.56 20
Pseudomonas fluorescens FW300-N2C3 0.59 AO356_00545 methionine synthase 0.56 AO356_21415 3-isopropylmalate dehydrogenase 0.31 63
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS13000 methionine synthase 0.57 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2464 methionine synthase (B12-dependent) 0.55 Psyr_1985 3-isopropylmalate dehydrogenase low > 86
Pseudomonas fluorescens FW300-N2E3 0.59 AO353_21615 methionine synthase 0.55 AO353_20635 3-isopropylmalate dehydrogenase 0.46 43
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_2847 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.54 PfGW456L13_3945 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2464 methionine synthase (B12-dependent) 0.55 Psyr_1985 3-isopropylmalate dehydrogenase low > 86
Dickeya dianthicola 67-19 0.59 HGI48_RS19130 methionine synthase 0.43 HGI48_RS18060 3-isopropylmalate dehydrogenase low > 71
Pseudomonas fluorescens SBW25 0.59 PFLU_RS13000 methionine synthase 0.57 PFLU_RS20565 3-isopropylmalate dehydrogenase low > 109
Enterobacter asburiae PDN3 0.59 EX28DRAFT_4326 methionine synthase (B12-dependent) (EC 2.1.1.13) 0.44 EX28DRAFT_3669 3-isopropylmalate dehydrogenase low > 76
Pseudomonas simiae WCS417 0.59 PS417_12310 methionine synthase 0.57 PS417_18585 3-isopropylmalate dehydrogenase 0.51 54
Shewanella oneidensis MR-1 0.59 SO1030 metH 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI ptt file) 0.39 SO4235 leuB 3-isopropylmalate dehydrogenase (NCBI ptt file) 0.75 14
Klebsiella michiganensis M5al 0.59 BWI76_RS01685 methionine synthase 0.44 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.60 24
Pectobacterium carotovorum WPP14 0.59 HER17_RS02310 methionine synthase 0.43 HER17_RS03080 3-isopropylmalate dehydrogenase low > 75
Acinetobacter radioresistens SK82 0.59 MPMX26_02351 Methionine synthase 0.54 MPMX26_00348 3-isopropylmalate dehydrogenase low > 36
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.59 GFF1358 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) 0.44 GFF165 3-isopropylmalate dehydrogenase (EC 1.1.1.85) low > 78
Enterobacter sp. TBS_079 0.58 MPMX20_00235 Methionine synthase 0.44 MPMX20_00768 3-isopropylmalate dehydrogenase 0.44 72
Pantoea sp. MT58 0.58 IAI47_17990 methionine synthase 0.41 IAI47_16005 3-isopropylmalate dehydrogenase 0.51 44
Escherichia coli ECRC62 0.58 BNILDI_06140 metH methionine synthase 0.44 BNILDI_08545 leuA 2-isopropylmalate synthase — —
Escherichia coli BW25113 0.58 b4019 metH B12-dependent methionine synthase (NCBI) 0.44 b0073 leuB 3-isopropylmalate dehydrogenase (VIMSS) 0.46 35
Escherichia coli ECRC102 0.58 NIAGMN_10990 metH methionine synthase 0.44 NIAGMN_08570 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli BL21 0.58 ECD_03891 homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent 0.44 ECD_00075 3-isopropylmalate dehydrogenase, NAD(+)-dependent low > 60
Escherichia coli ECRC101 0.58 MCAODC_03740 metH methionine synthase 0.44 MCAODC_01235 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC99 0.58 KEDOAH_14920 metH methionine synthase 0.44 KEDOAH_17435 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC101 0.58 OKFHMN_13240 metH methionine synthase 0.44 OKFHMN_10720 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECRC98 0.58 JDDGAC_16865 metH methionine synthase 0.44 JDDGAC_14315 leuB 3-isopropylmalate dehydrogenase — —
Escherichia coli ECOR38 0.58 HEPCGN_11885 metH methionine synthase 0.44 HEPCGN_08700 leuB 3-isopropylmalate dehydrogenase low > 85
Escherichia coli HS(pFamp)R (ATCC 700891) 0.58 OHPLBJKB_04030 Methionine synthase 0.44 OHPLBJKB_03584 3-isopropylmalate dehydrogenase low > 73
Escherichia coli ECOR27 0.58 NOLOHH_05380 metH methionine synthase 0.44 NOLOHH_03065 leuA 2-isopropylmalate synthase low > 57
Escherichia coli Nissle 1917 0.58 ECOLIN_RS23160 methionine synthase 0.44 ECOLIN_RS00395 3-isopropylmalate dehydrogenase low > 52
Escherichia fergusonii Becca 0.58 EFB2_04592 Methionine synthase 0.44 EFB2_03972 3-isopropylmalate dehydrogenase low > 86
Herbaspirillum seropedicae SmR1 0.58 HSERO_RS21740 methionine synthase 0.48 HSERO_RS16500 3-isopropylmalate dehydrogenase low > 78
Vibrio cholerae E7946 ATCC 55056 0.58 CSW01_02060 methionine synthase 0.43 CSW01_12600 3-isopropylmalate dehydrogenase low > 62
Dechlorosoma suillum PS 0.57 Dsui_0779 5-methyltetrahydrofolate--homocysteine methyltransferase 0.52 Dsui_3198 3-isopropylmalate dehydrogenase — —
Castellaniella sp019104865 MT123 0.55 ABCV34_RS14560 methionine synthase 0.46 ABCV34_RS04280 3-isopropylmalate dehydrogenase low > 48
Parabacteroides merdae CL09T00C40 0.48 HMPREF1078_RS14955 methionine synthase 0.33 HMPREF1078_RS16640 3-isopropylmalate dehydrogenase low > 61
Synechococcus elongatus PCC 7942 0.23 Synpcc7942_1372 metH methionine synthase (B12-dependent) 0.45 Synpcc7942_1505 leuB 3-isopropylmalate dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.22 AMB_RS02225 methionine synthase 0.55 AMB_RS20570 3-isopropylmalate dehydrogenase — —
Azospirillum sp. SherDot2 0.21 MPMX19_00637 Methionine synthase 0.64 MPMX19_00607 3-isopropylmalate dehydrogenase — —
Rhodospirillum rubrum S1H 0.20 Rru_A1531 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI) 0.57 Rru_A1191 3-isopropylmalate dehydrogenase (NCBI) — —

Not shown: 2 genomes with orthologs for Atu2155 only; 38 genomes with orthologs for Atu2791 only