Conservation of cofitness between Atu2209 and Atu2155 in Agrobacterium fabrum C58

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu2209 pyrroline-5-carboxylate reductase 1.0 Atu2155 methionine synthase 0.64 18
Sinorhizobium meliloti 1021 0.71 SMc02677 pyrroline-5-carboxylate reductase 0.79 SMc03112 B12-dependent methionine synthase 0.68 10
Rhizobium sp. OAE497 0.70 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.89 ABIE40_RS12135 methionine synthase 0.69 36
Rhodopseudomonas palustris CGA009 0.48 TX73_022630 pyrroline-5-carboxylate reductase 0.71 TX73_019180 methionine synthase — —
Azospirillum sp. SherDot2 0.48 MPMX19_01399 Pyrroline-5-carboxylate reductase 0.21 MPMX19_00637 Methionine synthase — —
Rhodospirillum rubrum S1H 0.45 Rru_A3281 Delta 1-pyrroline-5-carboxylate reductase (NCBI) 0.20 Rru_A1531 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI) — —
Magnetospirillum magneticum AMB-1 0.41 AMB_RS02820 pyrroline-5-carboxylate reductase 0.22 AMB_RS02225 methionine synthase — —
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.59 PFLU_RS13000 methionine synthase — —
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.59 PFLU_RS13000 methionine synthase — —
Pseudomonas simiae WCS417 0.36 PS417_26730 pyrroline-5-carboxylate reductase 0.59 PS417_12310 methionine synthase low > 88
Pseudomonas fluorescens FW300-N2E3 0.35 AO353_08165 pyrroline-5-carboxylate reductase 0.59 AO353_21615 methionine synthase low > 101
Pseudomonas sp. S08-1 0.35 OH686_10980 pyrroline-5-carboxylate reductase 0.60 OH686_03335 methionine synthase low > 80
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 PfGW456L13_2847 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 87
Pseudomonas sp. RS175 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase 0.60 PFR28_01369 Methionine synthase — —
Pseudomonas fluorescens FW300-N1B4 0.34 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 Pf1N1B4_5661 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) — —
Pseudomonas putida KT2440 0.34 PP_5095 pyrroline-5-carboxylate reductase 0.60 PP_2375 cobalamin-dependent methionine synthase low > 96
Pseudomonas fluorescens FW300-N2E2 0.33 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 Pf6N2E2_2068 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) — —
Pseudomonas fluorescens FW300-N2C3 0.33 AO356_13420 pyrroline-5-carboxylate reductase 0.59 AO356_00545 methionine synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.32 Psyr_0476 pyrroline-5-carboxylate reductase 0.59 Psyr_2464 methionine synthase (B12-dependent) low > 86
Pseudomonas syringae pv. syringae B728a 0.32 Psyr_0476 pyrroline-5-carboxylate reductase 0.59 Psyr_2464 methionine synthase (B12-dependent) — —
Pseudomonas stutzeri RCH2 0.32 Psest_0283 pyrroline-5-carboxylate reductase 0.61 Psest_2102 5-methyltetrahydrofolate--homocysteine methyltransferase — —
Acinetobacter radioresistens SK82 0.32 MPMX26_00572 Pyrroline-5-carboxylate reductase 0.59 MPMX26_02351 Methionine synthase low > 36
Castellaniella sp019104865 MT123 0.31 ABCV34_RS03610 pyrroline-5-carboxylate reductase 0.55 ABCV34_RS14560 methionine synthase low > 48
Dechlorosoma suillum PS 0.30 Dsui_0602 pyrroline-5-carboxylate reductase 0.57 Dsui_0779 5-methyltetrahydrofolate--homocysteine methyltransferase — —
Kangiella aquimarina DSM 16071 0.30 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.60 B158DRAFT_2466 methionine synthase (B12-dependent) (EC 2.1.1.13) low > 40
Shewanella oneidensis MR-1 0.29 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.59 SO1030 metH 5-methyltetrahydrofolate--homocysteine methyltransferase (NCBI ptt file) low > 76
Rahnella sp. WP5 0.28 EX31_RS02690 pyrroline-5-carboxylate reductase 0.60 EX31_RS11760 methionine synthase low > 89
Marinobacter adhaerens HP15 0.27 HP15_287 pyrroline-5-carboxylate reductase 0.62 HP15_1792 B12-dependent methionine synthase 0.44 55
Shewanella amazonensis SB2B 0.27 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.60 Sama_0758 metH B12-dependent methionine synthase (RefSeq) 0.87 62
Shewanella loihica PV-4 0.27 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.60 Shew_0710 metH B12-dependent methionine synthase (RefSeq) 0.89 38
Shewanella sp. ANA-3 0.27 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.59 Shewana3_3282 metH B12-dependent methionine synthase (RefSeq) low > 73
Pectobacterium carotovorum WPP14 0.27 HER17_RS03805 pyrroline-5-carboxylate reductase 0.59 HER17_RS02310 methionine synthase — —
Dickeya dianthicola ME23 0.26 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.60 DZA65_RS20250 methionine synthase — —
Dickeya dadantii 3937 0.26 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.60 DDA3937_RS19040 methionine synthase low > 74
Serratia liquefaciens MT49 0.26 IAI46_21415 pyrroline-5-carboxylate reductase 0.60 IAI46_23155 methionine synthase low > 86
Enterobacter asburiae PDN3 0.26 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.59 EX28DRAFT_4326 methionine synthase (B12-dependent) (EC 2.1.1.13) low > 76
Dickeya dianthicola 67-19 0.26 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.59 HGI48_RS19130 methionine synthase — —
Enterobacter sp. TBS_079 0.25 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.58 MPMX20_00235 Methionine synthase low > 85
Escherichia fergusonii Becca 0.25 EFB2_03670 Pyrroline-5-carboxylate reductase 0.58 EFB2_04592 Methionine synthase low > 86
Vibrio cholerae E7946 ATCC 55056 0.25 CSW01_02450 pyrroline-5-carboxylate reductase 0.58 CSW01_02060 methionine synthase low > 62
Escherichia coli Nissle 1917 0.25 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.58 ECOLIN_RS23160 methionine synthase low > 52
Escherichia coli ECRC102 0.25 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.58 NIAGMN_10990 metH methionine synthase — —
Escherichia coli ECOR27 0.25 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.58 NOLOHH_05380 metH methionine synthase low > 57
Escherichia coli ECRC101 0.25 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.58 MCAODC_03740 metH methionine synthase — —
Escherichia coli ECRC98 0.25 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.58 JDDGAC_16865 metH methionine synthase — —
Escherichia coli ECOR38 0.25 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.58 HEPCGN_11885 metH methionine synthase low > 85
Escherichia coli ECRC101 0.25 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.58 OKFHMN_13240 metH methionine synthase — —
Escherichia coli BW25113 0.25 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.58 b4019 metH B12-dependent methionine synthase (NCBI) low > 76
Escherichia coli ECRC62 0.25 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.58 BNILDI_06140 metH methionine synthase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.25 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.58 OHPLBJKB_04030 Methionine synthase low > 73
Escherichia coli BL21 0.25 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.58 ECD_03891 homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent low > 60
Escherichia coli ECRC99 0.25 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.58 KEDOAH_14920 metH methionine synthase — —
Klebsiella michiganensis M5al 0.24 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.59 BWI76_RS01685 methionine synthase — —
Synechococcus elongatus PCC 7942 0.24 Synpcc7942_2058 proC pyrroline-5-carboxylate reductase 0.23 Synpcc7942_1372 metH methionine synthase (B12-dependent) — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.24 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.59 GFF1358 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) low > 78
Mycobacterium tuberculosis H37Rv 0.23 Rv0500 Probable pyrroline-5-carboxylate reductase ProC (P5CR) (P5C reductase) 0.22 Rv2124c 5-methyltetrahydrofolate--homocystein methyltransferase MetH (methionine synthase, vitamin-B12 dependent isozyme) (ms) — —
Pantoea sp. MT58 0.22 IAI47_14945 pyrroline-5-carboxylate reductase 0.58 IAI47_17990 methionine synthase low > 76
Pontibacter actiniarum KMM 6156, DSM 19842 0.15 CA264_07730 pyrroline-5-carboxylate reductase 0.59 CA264_16785 methionine synthase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.15 ABZR88_RS09865 pyrroline-5-carboxylate reductase 0.61 ABZR88_RS20930 methionine synthase 0.79 18
Pedobacter sp. GW460-11-11-14-LB5 0.14 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.60 CA265_RS23440 methionine synthase 0.96 4
Parabacteroides merdae CL09T00C40 0.12 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.48 HMPREF1078_RS14955 methionine synthase low > 61

Not shown: 39 genomes with orthologs for Atu2209 only; 2 genomes with orthologs for Atu2155 only