Conservation of cofitness between ABZR87_RS18635 and ABZR87_RS19025 in Ralstonia sp. UNC404CL21Col

60 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS18635 multidrug transporter subunit MdtD 1.0 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.51 1
Ralstonia solanacearum UW163 0.78 UW163_RS21465 MFS transporter 0.91 UW163_RS21010 multidrug transporter subunit MdtB — —
Ralstonia solanacearum IBSBF1503 0.78 RALBFv3_RS17685 MFS transporter 0.91 RALBFv3_RS18120 multidrug transporter subunit MdtB low > 76
Ralstonia solanacearum PSI07 0.78 RPSI07_RS05895 MFS transporter 0.91 RPSI07_RS05515 multidrug transporter subunit MdtB low > 81
Ralstonia solanacearum GMI1000 0.75 RS_RS23315 MFS transporter 0.92 RS_RS22915 multidrug transporter subunit MdtB low > 80
Paraburkholderia graminis OAS925 0.62 ABIE53_003336 EmrB/QacA subfamily drug resistance transporter 0.65 ABIE53_001783 multidrug efflux pump low > 113
Paraburkholderia sabiae LMG 24235 0.61 QEN71_RS02875 multidrug transporter subunit MdtD 0.67 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 153
Burkholderia phytofirmans PsJN 0.61 BPHYT_RS15825 major facilitator transporter 0.65 BPHYT_RS07785 multidrug transporter low > 109
Paraburkholderia bryophila 376MFSha3.1 0.61 H281DRAFT_04102 drug resistance transporter, EmrB/QacA subfamily 0.66 H281DRAFT_06492 multidrug efflux pump low > 103
Cupriavidus basilensis FW507-4G11 0.60 RR42_RS32075 EmrB/QacA subfamily drug resistance transporter 0.78 RR42_RS03310 multidrug transporter low > 128
Variovorax sp. OAS795 0.60 ABID97_RS24975 multidrug transporter subunit MdtD 0.57 ABID97_RS20855 efflux RND transporter permease subunit low > 91
Xanthomonas campestris pv. campestris strain 8004 0.58 Xcc-8004.1610.1 MFS transporter 0.50 Xcc-8004.4792.1 Acriflavin resistance protein low > 74
Variovorax sp. SCN45 0.57 GFF2063 Uncharacterized MFS-type transporter 0.59 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) low > 127
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_4674 Permeases of the major facilitator superfamily 0.68 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein low > 103
Pseudomonas fluorescens FW300-N2C3 0.54 AO356_13775 EmrB/QacA subfamily drug resistance transporter 0.68 AO356_25875 multidrug transporter low > 104
Pseudomonas fluorescens GW456-L13 0.54 PfGW456L13_1079 Permeases of the major facilitator superfamily 0.68 PfGW456L13_3266 Acriflavin resistance plasma membrane protein low > 87
Pseudomonas sp. RS175 0.54 PFR28_04171 putative transport protein HsrA 0.68 PFR28_02194 Multidrug resistance protein MdtB low > 88
Pseudomonas fluorescens FW300-N1B4 0.54 Pf1N1B4_2413 Permeases of the major facilitator superfamily 0.67 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein low > 87
Pseudomonas fluorescens FW300-N2E3 0.53 AO353_07845 EmrB/QacA subfamily drug resistance transporter 0.68 AO353_22895 multidrug transporter low > 101
Pseudomonas stutzeri RCH2 0.51 Psest_0847 drug resistance transporter, EmrB/QacA subfamily 0.64 Psest_2139 Cation/multidrug efflux pump low > 67
Pseudomonas fluorescens SBW25 0.49 PFLU_RS28015 DHA2 family efflux MFS transporter permease subunit 0.67 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.49 PFLU_RS28015 DHA2 family efflux MFS transporter permease subunit 0.67 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 109
Pseudomonas putida KT2440 0.49 PP_4951 Drug resistance transporter, EmrB/QacA family 0.68 PP_3584 multidrug efflux transport system - membrane subunit low > 96
Pseudomonas simiae WCS417 0.48 PS417_26365 EmrB/QacA subfamily drug resistance transporter 0.67 PS417_12745 multidrug transporter low > 88
Serratia liquefaciens MT49 0.47 IAI46_18985 MFS transporter 0.65 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_4769 Major facilitator superfamily 0.65 Psyr_2483 Acriflavin resistance protein low > 86
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_4769 Major facilitator superfamily 0.65 Psyr_2483 Acriflavin resistance protein low > 86
Pectobacterium carotovorum WPP14 0.45 HER17_RS06310 MFS transporter 0.65 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 75
Rahnella sp. WP5 0.44 EX31_RS20305 DHA2 family efflux MFS transporter permease subunit 0.65 EX31_RS13380 MMPL family transporter low > 89
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.44 GFF3852 Multidrug transporter MdtD 0.63 GFF3854 Multidrug transporter MdtB 0.53 19
Enterobacter asburiae PDN3 0.44 EX28DRAFT_0481 Arabinose efflux permease 0.65 EX28DRAFT_0483 Cation/multidrug efflux pump low > 76
Escherichia coli ECOR38 0.44 HEPCGN_13430 hsrA putative transport protein HsrA 0.63 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB low > 87
Escherichia coli BW25113 0.44 b3754 hsrA predicted multidrug or homocysteine efflux system (NCBI) 0.63 b2075 mdtB multidrug efflux system, subunit B (NCBI) low > 76
Escherichia coli ECRC98 0.44 JDDGAC_18340 hsrA putative transport protein HsrA 0.63 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB low > 86
Escherichia coli ECRC100 0.44 OKFHMN_14720 hsrA putative transport protein HsrA 0.63 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB low > 80
Escherichia coli ECRC102 0.44 NIAGMN_12475 hsrA putative transport protein HsrA 0.63 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia fergusonii Becca 0.44 EFB2_04879 putative transport protein HsrA 0.63 EFB2_01780 Multidrug resistance protein MdtB low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 0.44 OHPLBJKB_04296 putative transport protein HsrA 0.63 OHPLBJKB_01629 Multidrug resistance protein MdtB low > 73
Escherichia coli BL21 0.44 ECD_03640 putative multidrug or homocysteine efflux system 0.63 ECD_01980 multidrug efflux system, subunit B low > 61
Escherichia coli Nissle 1917 0.44 ECOLIN_RS21590 multidrug transporter subunit MdtD 0.63 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB low > 55
Escherichia coli ECRC101 0.44 MCAODC_05225 hsrA putative transport protein HsrA 0.63 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB low > 87
Escherichia coli ECRC99 0.44 KEDOAH_13430 hsrA putative transport protein HsrA 0.63 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECOR27 0.43 NOLOHH_06855 hsrA putative transport protein HsrA 0.64 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB low > 75
Klebsiella michiganensis M5al 0.43 BWI76_RS19265 multidrug transporter subunit MdtD 0.65 BWI76_RS19255 multidrug transporter subunit MdtB low > 92
Escherichia coli ECRC62 0.43 BNILDI_04670 hsrA putative transport protein HsrA 0.63 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB low > 75
Pantoea sp. MT58 0.43 IAI47_06860 multidrug transporter subunit MdtD 0.63 IAI47_16895 efflux RND transporter permease subunit low > 76
Enterobacter sp. TBS_079 0.43 MPMX20_03063 Putative multidrug resistance protein MdtD 0.65 MPMX20_03061 Multidrug resistance protein MdtB low > 85
Dickeya dianthicola ME23 0.42 DZA65_RS16175 MFS transporter 0.64 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 75
Dickeya dadantii 3937 0.42 DDA3937_RS15275 multidrug transporter subunit MdtD 0.64 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 74
Dickeya dianthicola 67-19 0.42 HGI48_RS15355 multidrug transporter subunit MdtD 0.63 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 71
Azospirillum brasilense Sp245 0.34 AZOBR_RS03675 major facilitator transporter 0.46 AZOBR_RS14670 multidrug transporter low > 97
Dyella japonica UNC79MFTsu3.2 0.34 ABZR86_RS01865 MFS transporter 0.50 ABZR86_RS16320 efflux RND transporter permease subunit low > 74
Bosea sp. OAE506 0.33 ABIE41_RS15195 MFS transporter 0.43 ABIE41_RS20140 efflux RND transporter permease subunit low > 77
Azospirillum sp. SherDot2 0.32 MPMX19_02331 putative transport protein HsrA 0.57 MPMX19_05477 Multidrug resistance protein MdtB low > 112
Rhodopseudomonas palustris CGA009 0.32 TX73_011345 MFS transporter 0.52 TX73_013310 efflux RND transporter permease subunit low > 86
Rhodanobacter denitrificans FW104-10B01 0.32 LRK54_RS17430 MFS transporter 0.51 LRK54_RS09845 efflux RND transporter permease subunit low > 59
Rhodanobacter denitrificans MT42 0.31 LRK55_RS17650 MFS transporter 0.50 LRK55_RS09505 efflux RND transporter permease subunit 0.76 42
Castellaniella sp019104865 MT123 0.31 ABCV34_RS14570 DHA2 family efflux MFS transporter permease subunit 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit low > 48
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_07515 MFS transporter 0.50 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB low > 52
Sinorhizobium meliloti 1021 0.29 SMc00813 transport transmembrane protein 0.21 SMc01457 transport transmembrane protein low > 103
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF189 MFS permease 0.59 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA low > 90

Not shown: 5 genomes with orthologs for ABZR87_RS18635 only; 11 genomes with orthologs for ABZR87_RS19025 only